mpidb The Microbial Protein Interaction Database harriff-2009-1 Mycobacterium avium genes MAV_5138 and MAV_3679 are transcriptional regulators that play a role in invasion of epithelial cells, in part by their regulation of CipA, a putative surface protein interacting with host cell signaling pathways. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Harriff M.J., Danelishvili L., Wu M., Wilder C., McNamara M., Kent M.L., Bermudez L.E. J. Bacteriol. (0021-9193) 2009 Only protein-protein interactions imex curation cdc42_human Cell division control protein 42 homolog CDC42 G25K GTP-binding protein protein protein human Homo sapiens Human MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL a0a0h2ztm2_myca1 MAV_4139 protein protein strain 104 Mycobacterium avium MADLPFGFSSGEDPDKPGKKDPDSGSNPSDPFAAFGISGEFGMGDLGQIFTQLGQMFSSAGSASAGGSDSGPVNYELARRVASNSIGFVAPIPATTNSAIADAVHLAETWLDGATALPAGTAKAVGWTPADWVDNTLGTWKRLCDPMAQQISTVWAASLPEEAKSMAGPLLQMMSQMGGMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGIAAILPDAVESFASGLERPRSEILTFLAAREAAHHRLFSHVPWLASQLLGAVEAYAMGMQIDMSGIEELARDFNPASLSDPAAIENLLGQGVFEPKATPAQTQALERLETLLALIEGWVQVVVAAALGDRIPGAAALAETLRRRRASGGPAEQTFATLVGLELRPRKMREAAALWERLTEAAGVDARDGIWQHPDLLPDADDLDDPAAFIDRVIGGDTSGIDEAIARLEQEGPDSPGSGGGDT a0a0h3a2t3_myca1 MAV_1190 protein protein strain 104 Mycobacterium avium MALALGSGGARGYAHIGVIEALQARGYDIVGVAGSSMGALVGGLQAAGRLDEFAEWAKSLTQRTILRLLDPSISAAGVMRAGKILDAVRDILGPVAIEDLRIPYTAVATDLLAGKSVWFQRGPLDEAIRASIAIPGVIAPHTLDGRLLADGGILDPLPMAPLSAVNADLTIAVNLSGSEAITRREAEPAATAEWLTRMMRSTSALFDTAAARSLLDRPTARAVLSRLGGPSGDADAWPDNPEEPDQPVLADDDDEAVELPGAATDVPKLGSFEVMNRTIDIAQAALARHTLAVYPPDLLIEVPRSICRGLEFHRAVEVIDAGRALADQALDALEDGDDDRPAVER a0a0h3a1l5_myca1 MAV_4671 protein protein strain 104 Mycobacterium avium MTNPQGPPKQDPSTWGRPANQGPYGQPPTERPTERINTGGPGQAPGQVPPPPPAPAPPPPGQTERFGTPRPQMQQPGYPPPPTPPAGPTERLATAPNPDNGPAKKKRRFLRDPVSVLLIFIIVFALIIAGFIGAELYVRHVADTKVAQAVACEVKDQATASFGVTPLMLWQQATKHYTNISVQTAGNNIRDAKGMKLSININDVRLKDNGNSKGTIGALDATIDWTTDGIKQSVQNAIPVLGPFVTNTVTTHPADGTIELKGMLDNITAKPVISGTGLQLQIVSFNALGFTMPKESVQSTLDDFTSNLTKNYPLGIHADSVQVTDKGVTSHFSTRNAAIPTGNNNDPCFANL a0a0h2ztd1_myca1 Diacylglycerol O-acyltransferase MAV_4952 protein protein strain 104 Mycobacterium avium MKRLSGWDSVLLYSEAPNVHMHTIKAAVIELDADRRSLDVAAFRQVIAGRLNKLDPFCYQLVEVPFSFHHPMWRENCEIDLDYHIRPWRVSPPGGRRELDEAIGQIASTPLDRSRPLWEMYFVEGLANNRIAVVGKIHHALADGVASANLLARGMDLQPGPEAGPYVCDPPPTTRQLMVSAFADHLRHVGRLPHTIRYTAQGLGRVRRSARKLSPELTRPFEPPPTFMNHKLTPERRFATATLALADVKETGKRLGATINDMVLAMSTGALRTLLLRYDGQAQPLLASVPVSFDFSPERISGNRFTGMLVALPVDHDDPLERVAACHQNAISAKESHQLMGPELVSRWAAYMPPAPTRAFFQWASARDGHNKILNLNISNVPGPRERGRVGGALVTEIYSVGPLTAGSGLNITVWSYVDQLNISVLTDGATCKDPHEVTEAMVQDFIEIRRAAGFSEDLTVVEAAMAPA a0a0h2zzs9_myca1 MAV_1043 protein protein strain 104 Mycobacterium avium MPARRHLYFAYGSNLCARQMAQRCPDAADPRPAVLADHDWLINQRGVATVEPLAGNQVHGVVWRISDGDLATLDSAEGVPVRYRRDRLTVHTDDGPAPAWVYIDHRVTPGPPRPGYLPKIVDGATQHGLPQRWIDFLRRWDPAGWPSPRATSPSNRIGPQSLSALLRVTGVTESSQLRSGFGFLAIHGGGLEEMTDVIAERAAAAAGASVYVVRHPAAYPHHLPSARFDPAESPRLAEFLDHVDVAVSLHGYGRDGRSTQLLAGGRNRALADHLARHVRLAGYRVITDLEDIPAELRGLHPANPVNRVRDGGVQLELSARVRGLSPRSPLPGDDGLSPVTGALIQGLADAARCWSMSDH a0a0h3a2d0_myca1 MAV_1300 protein protein strain 104 Mycobacterium avium MITEPATAFSRVFRGYDPAAVDAYVEALLAKQKLLIDEVQNLRAQRNESGDQLAALRIEVACLKDEVAHLSDTSPTPYAIQHRMTKMLRRTLEEISRMQAEAQAEAESMIAAAAAQVEASHREHQELLADMAAQREALETEREEAKKELEAELATMRAEARASIDEARREAERECARLLAEAKQKADDLDERARRTVEEANQQRIMILEELMDVARDLQGLPASLESAYQERTSPSEASVVVPLDPKNQAPGPAVAS a0a0h2zxu9_myca1 MAV_3034 protein protein strain 104 Mycobacterium avium MDRFAGRRAIVTGAGSGIGAATAARLLDEGATIVAYDISAEGLARTRAAADDAGTGKRLTTAVLDISVEGDVIAAVDAAVADLGGLEVLVNVAAIQTCSHTHQTTLADWNRTLAVNLTGTFLMTRQALPALLDSGRGVVVNFTSTAASFAHPYMAAYAASKGGILSFTHSLALEYAKQGLRAVNIQPGGVSTALANSTLDKMPDGYDVGLWAKQTPLLHGKDSEILGDPSAVASVIAMVASDDGAFITGTEIRVDGGAHA a0a0h3a355_myca1 Mutator family transposase MAV_2074 MAV_4319 protein protein strain 104 Mycobacterium avium MVKRPRITTERNIAMALDQSALLEVLDALRNADAADRIKQAAETIYQALIDAELTAVIGAGPHERSASRTNQRNGSRPRTLSTIAGDLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHGTSTRKVDDLVKALGADAGISKSEVSRICADLDTEVGAFRDRPLSEQHFPYVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFDVGDSEDGAFWTAFLRSLKTRGLSGVQLVISDAHTGLRSAIEAILIGASWQRCRVHFLRNVLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQLPKVETMLREAADDITAFADFPVLHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPAALLRLAGSVLVEAHDEWQVAEKRYLSETTLALLHPRSDSADQSVAVPAAITA a0a0h3a0j9_myca1 RNA polymerase sigma factor SigA sigA MAV_3595 protein protein strain 104 Mycobacterium avium MKRTATKSPSSPAKRPAAKAANGSAPAKRATKTASRSAKSEAGAAAEPAKKTRSSAKGADAKAPSGRGTKAAKGGPADPDALDTDGAVEDLDTEPDLEGEPGEDLDIDTDLNLDDLEEDVAADDADIEPGDAEEGEDEEAAAPKAAGATAADEDDEIAEPSEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKVALLNAEEEVELAKRIEAGLYATQLMSEMAERGEKLPAAQRRDMMWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD a0a0h3a069_myca1 MAV_0876 protein protein strain 104 Mycobacterium avium MTGSGTGSQTLARGLTALQMVADAPAGLTVQQLADQVGVHRTIAYRLLTTLAEFRLVAKGEDGRYRPAAGLAVLGASFDRNVRQLCLPTLRALADELGTTVSLLVAEGDQQVAIAVIVPSHVAYQLSFHEGSRYPLDRGAAGIALLACMPPRPGERELVSRARERGWVTTYGEIEPNTYGLAVGVRRPAPSPPTCINLISHREDVVMRGKDAVMRAAEQLSKLLS cdc42-a0qk49 1334956 not-defined-560706829 1334957 unspecified role unspecified role bait bait not-defined-334375585 1334958 unspecified role unspecified role prey prey physical association physical association false false false cdc42-a0qbz8 1334956 not-defined-594387335 1334957 unspecified role unspecified role bait bait not-defined-375010804 1334959 unspecified role unspecified role prey prey physical association physical association false false false Table 3 cdc42-a0qll1 1334956 not-defined-1705401841 1334957 unspecified role unspecified role bait bait not-defined-1730320469 1334960 unspecified role unspecified role prey prey physical association physical association false false false Table 3 a0qll1-a0qmd5 1334956 not-defined-907973147 1334961 unspecified role unspecified role prey prey not-defined-164952978 1334960 unspecified role unspecified role bait bait physical association physical association false false false Table 3 a0qll1-a0qbl0 1334956 not-defined-1354927521 1334960 unspecified role unspecified role bait bait not-defined-1681389850 1334962 unspecified role unspecified role prey prey physical association physical association false false false Table 3 a0qll1-a0qca7 1334956 not-defined-1640320206 1334963 unspecified role unspecified role prey prey not-defined-1685408771 1334960 unspecified role unspecified role bait bait physical association physical association false false false Table 3 a0qll1-a0qh32 1334956 not-defined-783108540 1334960 unspecified role unspecified role bait bait not-defined-984907890 1334964 unspecified role unspecified role prey prey physical association physical association false false false Table 3 a0qll1-a0qef2 1334956 not-defined-1355523359 1334960 unspecified role unspecified role bait bait not-defined-1724177048 1334965 unspecified role unspecified role prey prey physical association physical association false false false Table 3 a0qll1-a0qin4 1334956 not-defined-1669320869 1334960 unspecified role unspecified role bait bait not-defined-1082809182 1334966 unspecified role unspecified role prey prey physical association physical association false false false Table 3 a0qll1-a0qb55 1334956 not-defined-1938773407 1334960 unspecified role unspecified role bait bait not-defined-1131077075 1334967 unspecified role unspecified role prey prey physical association physical association false false false Table 3