<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2013-02-01Z">
            <names>
                <shortLabel>mpidb</shortLabel>
                <fullName>The Microbial Protein Interaction Database</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0903" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6390654" refType="identity" refTypeAc="MI:0356"/>
            </xref>
        </source>
        <experimentList>
            <experimentDescription id="1333968">
                <names>
                    <shortLabel>agari-2008-1</shortLabel>
                    <fullName>Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18699868" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6403968" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-18223" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Agari Y., Kashihara A., Yokoyama S., Kuramitsu S., Shinkai A.</attribute>
                    <attribute name="journal" nameAc="MI:0885">Mol. Microbiol. (0950-382X)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1333969">
                <names>
                    <shortLabel>sdrp_thet8</shortLabel>
                    <fullName>Transcriptional regulator SdrP</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein SdrP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Oxidative stress-responsive transcriptional activator SdrP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Stationary phase-dependent regulatory protein</alias>
                    <alias typeAc="MI:0305" type="locus name">TTHA1359</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q5SIL0" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblbacteria" id="BAD71182" version="SP_115" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390"/>
                    <secondaryRef db="ensemblbacteria" id="BAD71182" version="SP_115" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001216" secondary="DNA-binding transcription activator activity" version="SP_115"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018490"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_011173413.1"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6403973" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_115"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014710"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006979" secondary="response to oxidative stress" version="SP_115"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ZCW"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012318"/>
                    <secondaryRef db="ensemblbacteria" id="BAD71182" version="SP_115" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000595"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="YP_144625.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_115"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_115"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="300852">
                    <names>
                        <shortLabel>thet8</shortLabel>
                        <fullName>Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)</fullName>
                    </names>
                </organism>
                <sequence>MTQVRETVSFKAGDVILYPGVPGPRDRAYRVLEGLVRLEAVDEEGNALTLRLVRPGGFFGEEALFGQERIYFAEAATDVRLEPLPENPDPELLKDLAQHLSQGLAEAYRRIERLATQRLKNRMAAALLELSETPLAHEEEGKVVLKATHDELAAAVGSVRETVTKVIGELAREGYIRSGYGKIQLLDLKGLKELAESRGQGR</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-18223-1" id="1333970">
                <names>
                    <shortLabel>q5sil0-q5sil0</shortLabel>
                </names>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="2ZCW" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-18223-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6403977" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mpidb" dbAc="MI:0903" id="MPIDB-INT-53" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1333968</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1333971">
                        <names>
                            <shortLabel>not-defined-1603380912</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6403981" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1333969</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1333972">
                        <names>
                            <shortLabel>not-defined-763616317</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6403980" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1333969</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="3d-resolution" nameAc="MI:0632">1.5A</attribute>
                    <attribute name="3d-r-factors" nameAc="MI:0631">Rworking = 0.22 Rfree = 0.23</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">Table 1</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
