IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ cuppen-2003-2 Proteins interacting with Caenorhabditis elegans Galpha subunits. caeel-mixed_stage Caenorhabditis elegans mixed stage organisms mixed_stage C. elagans mixed stage organisms 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Cuppen E., van der Linden A.M., Jansen G., Plasterk R.H. plasterk@niob.knaw.nl C. elegans prey cDNA library, gift of R. Barstead. Comp. Funct. Genomics (1531-6912) 2003 Only protein-protein interactions imex curation cuppen-2003-1 Proteins interacting with Caenorhabditis elegans Galpha subunits. caeel-mixed_stage Caenorhabditis elegans mixed stage organisms mixed_stage C. elagans mixed stage organisms 2h fragment pooling two hybrid fragment pooling approach 2h fragment pooling nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Cuppen E., van der Linden A.M., Jansen G., Plasterk R.H. For interactions involving GOA-1/C05D2.6 and also T22A3.3/GPA-6: the amino acid numbers given for the "fragment" exceed the length of any of the molecules involved in the interaction. plasterk@niob.knaw.nl C. elegans prey cDNA library, gift of R. Barstead. Comp. Funct. Genomics (1531-6912) 2003 Only protein-protein interactions imex curation nhr22_caeel Nuclear hormone receptor family member nhr-22 nhr-22 K06A1.4 protein protein caeel Caenorhabditis elegans MSTDLLYEYFYPPTDLFKNTFEDVPPSPESLDVGDSLGSSPSYDLGFQPSFDIDFCIWKEGSSSPPPESNHLPEIVNKASTSPRGMPSPLTDSRSCHVCSSPTANTLHFGGRSCKACAAFFRRSVSMSMTYECIGTGDDTNPCRTHYELRMICRHCRFIKCLDAGMRRELVQARKEETRVAKRRSKGLVVSKKEDDDVESSYDEYVNTYTNVQDSSPKMESGINEMTIPESYLSPDPSSSQPLDMTVTPPPLHRSTPSILLTPATGDRMHCQRVLSNSPPFDIHQASTSHAGFIQHVQFYPVVEVENKIFELVDHYVRTEASLNDRRKIMYTDTQIRDVFDTTCECPYENHQLKPFNYKSFCGFVKHDFVMILDYVNQFPEFQALHKNDKNVVYRMACAVDSMLASAYYSYKVGIEKERLILFNGDYINMNPIPISGDEPGAGTEFQTPQEHEKYKTLMPLKLKQYFDLAIPFARLEVSFEEYVLLKALIIWQISNYRLLEEGRAICARQRDTIVQALHKVVEERGDEDPAIRVGQLLLSMSYITEQVQAMTNSYLVMTFFDVVSCDSIMYDLLSFRDD gpa7_caeel Guanine nucleotide-binding protein alpha-7 subunit gpa-7 R10H10.5 protein protein caeel Caenorhabditis elegans MGHCTSKDQKEGKRLNRRIDEQIKKDQSMSLRIIKLLLLGAGESGKSTILKQMRILHKDGFSQQDLEMIRPVVYSNCIHSMLSILRAMFHLQIEYGEPDRVRDSQLVFATVHANKEELTEELAAAMQRLWHDPGVRECYRRSNEYQIDDSAKYFLDNLPRLSSPNYVPSEQDLLRTRIKTTGITEVLFELKGLTFRVIDVGGQRSERKKWIHCFDNVNAIIFISSLSEYDQTLREDNCTNRMQESLKLFDSICNSPWFADIHFILFLNKKDLFAEKIVRSPLTVCFPEYKGQQNQTECINYIQWKFEQLNRSSQREIYCHHTCATDTNNVQFVLDACLDMIIAKNLKSMGLC nh114_caeel Nuclear hormone receptor 114 Y45G5AM.1 nhr-114 protein protein caeel Caenorhabditis elegans MTPQSSPSSSRDHVCLVCQDFASGYHYGVPSCVGCKTFFRRTIMKKQKYICQFEGNCPVDKTIRCACRYCRFEKCLSVGMDRNALQQNRDPIGYTKRTRRPKKELKTTSDCSSDEGASTPPSVSPLQLSPPPISPLLFQAAPLKPRRCILQTLAEREKCANDLRLSEYLPIRSLHEALCSKALLNDTAFLEKWGQPSERHQIFDLRFVNHDDYHYWHERDWFLLTEYAKTFDVFEALDYQDKAELVRHAAITVPVLVQVWNSPDYGPDTIVFPDGAYFDRTPEPTRPAGLNRKKYQMLDLVLKPFRDLQLDATEFAAFKAVTFLNPDADISLPARKLVNNERVRITKQLYGYMAMKDDVDTAIERFARLVLMGTSMSKMACESKEAVWIADFFENIGFSAFARQLFFGDTTSVVAHKL gpa13_caeel Guanine nucleotide-binding protein alpha-13 subunit gpa-13 F18E2.5 protein protein caeel Caenorhabditis elegans MGCNFSSQSKLQVPEIRASRSITPASQKSEDPYSHIRLLLLGSAESGKTTVLEQVRLLYKQHFTESEYFHRRAFIYHNIFKSIKALCRAMRMSDIQFADPINMGRAQSIIADEHGHYGLFSKDLAEKIKHIWNDKSMQKLYARRSQFNLNDSASYFLNNIDKINMVDYKPSERDLIMAYVPTCGVQNVIFTACNQSFQLFDIGGQKIDRRKWALQYEGIDAIFFCIAISEYDQVMSEDMVTNRLDDALNLLQSISEDPAFATTPIYLFLNEIDVFCEKLSVIPLSKYKPDFKGGDQDDAIDFMENLACEALGKRDRSLYRVYRCIAIDTQMMAELLSTVFKDIAKRKK gpa6_caeel Guanine nucleotide-binding protein alpha-6 subunit gpa-6 F48C11.1 protein protein caeel Caenorhabditis elegans MGAGATGLRGARLSPEERANSSKSRAIDRALSKDHTDDLNRFKILLLGTAESGKSTIFKQMRVLHLDGYAKEDALEYLSIIHSNCMEALTQLVDACTAFGINHDITVQEDVNRFEDFKRKLRDPEGLVIPVVIGRCMDRVWHSPSLQLCYDTRRFRFALLDSAKYFMDNIVRLTEDNYVPSIQDIVHCRISTTGINELAFNYKKMDFKMVDVGGQRSERRKWIHCFDNVDMILFIVSMSDYDQLDPEDNKYNRMKQSYEIFKTIVHSDLFRHASIVLFLNKYDVFVEKLKTSPLRRSFKNYEGDNSEESAREFIKKLFRRCITDRHKFFVFETTATDTGNIDLVFGSAVAHIVNENLRSAGLHE q86rt0_caeel protein protein caeel Caenorhabditis elegans RNNCNKSSSTIAYSKSQHEAPKQLLQLRSEIKPLIPLNQPSNFWESSQDSGVLSSLSSSPQQRSGLRSQKLHLTYIEKNKRVRAMIPQQQHYHAFDRPTHYNSRKTSGPPPLMRTPSSGFSSASSSENMFSGLTLSDNENKIHEIMDPSVDVDLDMFLLPDCRYKQPVQPSTSTSRNNVSQISGSSRLNGSTRHVAPIVPKVAMPSELSYANVKRSSGYVDYMPTTYNSNVTSNSSAASVPMSPGTWVRCHYCWESYVKLCQRVANLEPLISCDGPWNWHTLYDMQGRVTCPRLWFAQLDRAGSEMVEQMGHARNVPV gnao_caeel Guanine nucleotide-binding protein G(o) subunit alpha goa-1 C26C6.2 protein protein caeel Caenorhabditis elegans MGCTMSQEERAALERSRMIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDYKQYKPVVYSNTVQSLVAILRAMSNLGVSFGSADREVDAKLVMDVVARMEDTEPFSEELLSSMKRLWGDAGVQDCFSRSNEYQLNDSAKYFLDDLERLGEAIYQPTEQDILRTRVKTTGIVEVHFTFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPEYSGRQDYHEASAYIQAQFEAKNKSANKEIYCHMTCATDTTNIQFVFDAVTDVIIANNLRGCGLY q86rs9_caeel protein protein caeel Caenorhabditis elegans DWIYSWKDSIFYGMCSCSGSPSYHEKDVPHPHDRLDMPLQLKAYRRNSLNAEGYYRDLERMHERGLFTTGINYNAEKSEDFLNMIERMQSNRLDDQRCEMPERTHNPTSGHQNEQTHQKTNGSAVHNQLTRNIMNEVLTKVGPYPQIVLPSNGFWMDGVNQQHHMDDQVNNMNVNSCARFKLETDETSHCYRRHFFGREHHDFFANDPIVGPLVLSVRTEVISSCDHFRIILRTRKGTIHEIVSATGLADRPSASRMAKLLCEEITTEQFSPVAFPGGSELIVQYDEHVLTNTYKFGVIYQKGGQTTEEQLFGNPHGSPAFDEFLSMIGDSVQLNGFQKYRGGLDTAHNQTGHQSVFSEFKNREIMFHVSTMLPYTIGDAQQLQRKRHIGNDIVAIIFQEANTPFAPDMIASNFLHAYVVVQPIDALTDRVRYRVSVAARDDVPFFGPTLPTPSIFKRGQDFRNFLLTKLINAENAAYKSSKFAKLAERTRSSLLDGLHATLRERAEFYATPLLESTSSGGESAATTSSSSNSYGGGILSSVKKAFIGRSRSVSQEASHVPHRAATINVTSRPKKSISSTSSSTSARTHSPIRDEEVVKPYRKEWEISSQESPDNEHDSDTGMESMSSTEMSGQTRASSCTFCVDDFHVAANHQSSDAKRLETLCVDVTRLQNEKHDLLRQNVSCKTDIKKLKDRQSVLSEELERANDEISRLRRMLKKPSNSDMAPVHQHFERSYSDVSV q19955_caeel ags-3 F32A6.4 CELE_F32A6.4 protein protein caeel Caenorhabditis elegans MQDRSCYKLTQEGERLFRMQKYEKGIDLLKKALEVGTDDFSLLSAIYCQLGNAHTMLKDYEQALKFHTYDILVERLLGNKEGEAKSCANLGNIFKMKGAYNDALTFTFKQLDFAEELGDRVLKSRAYYNIATIYVERGRCTKLEAAEEKNDAKNAEATSDFENAAKYFMLNLEMSEKSEDALTMGRCYGSLGNTYYCLGDYDQSIHFHKLRLELSQQYGDRASMRRAHANIANCHALKSNMPLAIQHYKLAYNLAIEIGNKTEEAQMAYSLANALYIGKEVQKAITYFQRHLKIARSLEDISGQLRSYYSLALSFNNLCERRKALYFLVLAKRSSLQVNDTSALTDIDNLLNEILEAGQEDVLVDDIELIIDESADPAPADIEHRELRLTYFQKRNIHDKPVNTPEDPLAEDRYEKEEFFDMLAKLQSKRMNDQRVDASVLSSNLDFRVRQVDTEPDNSSTDGSEVLIDLLLNAQGRRMDDQRAPFLPGLNPNGQIILRRLNTDPGNEELDEHLVEWLMRVQGERLDEQRSELPPIKPEGQEEVDKKKEEDVTAIVMRMQAGRLEDQRAHLPNIPTSKN gbas1_caeel G-protein alpha subunit activating protein gbas-1 gbas-1 F59H5.1 protein protein caeel Caenorhabditis elegans MRSVRSSSRTPKPVKRFVFDEDEDLEEIDLDEVDNADFEREDDEEEVLSEPSESPYTSTPKSSKRVNKTRGTKDFFKKDESLQLFRFVLNECRSQKPGRVGRVAKKRVGVNSMKYWERYKREIQGYRLPKQYRYHYSFYSKCFYKVLGLTPEEKVDLYYACEMPVVTDAEKQWLVEQFHVEFDEFGVIIGSDVCTHWDEEHSDSEDDSGKKEEKAREVSRYTEYHDDMMWKFIVDKISEGAQPIIDKHPIWDEFVKLNEENDVISKKSGRNHYDRFRRILVPNLHFMPYDDFTKAVLYERLEYPIPEEYRKILFTTTGADINESGFIEYLPPSTIHQISPIVPIPCHKSNPKFSQLKEPKDLILWSERKKFTPREDSQIWEFVRRKCVDSAGIFVKNDVLRGRGTLFFKDFRNTERKYESITQRFVVLRKLIMDTDYSLKQKLEIYYAISQPVDEDALDAFKSIACLVLNPDGTIRFAISKSFLIGRISDEPAKLEAENYSYVYDLFIFNETFGTAENPEPLCSVSQNRAEKFMLVSQLVFRFISRFEALEDRRIAWITPNAQVAPKEPVPAPSKKKSAFEAYQSSPQTFDTIQRFSTKRPFFCGDNFQIPPKKPFLAEEDVKLEPMEYENSEQIVENAEIKLEPAEELLDAETVTVEEFLMNSYSTAAPSTSTAPAPPKAPVTAPPAPQKSAQLLGKIDFAIGKMRENFDRFLQFAQQNSADLTVVQRYRYDAQMQQMTEKFTKDVSKVLSGDSIKR g5ee25_caeel Non-specific serine/threonine protein kinase hasp-1 C01H6.9 CELE_C01H6.9 protein protein caeel Caenorhabditis elegans MPPKPRIKVPISPGKKARNNFARRNRQLSSVIITECPIDFPEYEFSKNPALFKSFNDNPEFKPSKKKNKPKPVFPPSPNVSDVEISSDEEDAGQFKVPDADADEEEKIKKIKEAFDSLDDVSLEVFNNDGIRVKIENGKHIIHDKQPEEAWRPGIREYHDGNFPMMNKPAKKIDFAKKMEQRQKKPVKQVPEMNSKANQVQCPTNYASFCGSILADHMRQNKKASLAAPSLFRVFGTPQRSKMIVPAKHVQCQDERLAIYSYTPIRVNKTAKQLDDTIGSIVFSPKTQNASTPIEKQTAGRRPKSFPVFDVSLNDSCENITKKEEQIAQKSANSDQKETTINNIPIEEEYSGRVHESSLAGSIQQPQQDLEETAISENRLSHSTLKTTPIESRNESHQNSKIMTQQVSDSEDVEDVTFNRKAETSVTELLHEEDEHERCSDLNLEESKYSKKRQRTKSPETMCQGMSTVMTMQDDQDDLEALFEIEKENEIRKRTTLQPQQRQRDRESRVSRLSVMSAASSRHDSINSAMEEMSLQQFLEDTMGEEFGKTQYSESRAESRNIPTGMTIHNEDPSILPFYLEDLTSEIDPSPMMQLLHVVGQKESKTWDSLPKSALDGRRVKKLGEGAYGEVFSTIWDGKPVAIKIVPFEKDGCNRQYFGEYHSEEMQTSDVVLPEVIVMKELSALRDEDAWNSTPNFIEMISAEVVMGKYPKGLLSAWDSYDKLKESENTRPDVYSSIDQNFILFVSANGGIALEDFVLESENELFSIIHQLVLSMNAAEAALEFEHRDLHLGNVLIDRNGVKELYYTVHGQKVPLSTHGIKVNIIDFTLSRISKGATTVYWDLENDPAIFEGQDDPQFEVYREMRKNCKSNWKKFSRRTNLMWIVYIANRLIDTKICPKGLLTEKRRMELKVLFDRFAEFGSCGESLTNEEFFSDFYEGPIGMSTTRQ lin36_caeel Protein lin-36 lin-36 F44B9.6 Abnormal cell lineage protein 36 protein protein caeel Caenorhabditis elegans MSEELLSTRPSKRDYNDIEEPEDSHVTVHSVEQDSQHSGEESSTVDALQETEGDVDVIGEDEDEHDIPVMPTVTSSGEVLDESQVTPTKQASSSQPREEIIHGKGESVYSSFPCQVIPETLSRMTRTPPDGEHLEVYRMSNGRLRIYVVDHFKKFSPYSNLTHKPCTVCNRVMKSGEMHLNFPADLDRRRIWANLLGFKYKDILRSKMGPVSFSIAAGPICTEHFAEECFRNHNFNKSAIEAFGVPVAISPDVKTTPSKKSSRVPWVCTVCEFHSCSVVELQTHLLNHTEEMLKKKDNVLDVPEAGFMCPFCRKCTYGYKTISGYRRHLNAGPIHHCHLRRIYEFAKMNCRATELDPAESWDNWTRRNVYVAYHGCEPPANEIVLTPSPTKKAYVQNPEERTKMVHDEEKRKKAVRTLSFVGKEGGTSVNDLNVMQRQVFLQLRREAEINTKAEESAQGTKEQESSQKKHAEEESDDVSELTSHQSPQAPMGSGERRKATRLATSATNSPIKKVAKHEVPATAPSTPAKKRKISHEEEHDPTPESVEREPTVSPNDPRERLRLKERDEQFAKMVQKRSQQVKRLINAKQFKKQEAATKKPRKALAYNLAKGIAATSSTEPEDKVTSSEQTPEPTTSQKFIARNTRSKTKESAVQKVEKPATPVAKPAPVEKEPEERPLKSMLARSFVAGVRPSMAKYQIPLESFTATASLGGGRSLSSGVISRPPTSSSPGGIFSQRVMGAVAQEKGPAKRPSVLSRRPLILSPRKKTSTPRPTLSHHESSPNFSASSPVVVSDEYLIPATDMEVEMVEEVIDSMGNSSSEDVATSSTSSERQPMLTLAEALEMDGSSGTVKDQDMEEISKEMMKDAHYYRAMEDAIKCRTVTKMRADMRLSRHCIRQIEAARARARLFGERTEDYQIFYSNDGAQVLTKKDPKWRELQQQQQQQQQQQEQFPGQGSSDSQQ q86rt5_caeel protein protein caeel Caenorhabditis elegans DKDFYNDVPLAEDVLEPGQSLGNSESMKFDYVVIQPHVRPHQQIPTSSYSRRKSPQSRETEAIVRTYPLSPKRIVQQHRMPQKNNPDQQHQMNEVKKEVNPFGRQGVLVEVEPSPSYAQSNTKIYKMVSAHRSATPQPAVTVASSRRLVHMPHRTNSLVYDSMPELIDSSNMPSEPPKKKIHLEVGHRNSEMVGVSTSSNAPCLPKEILTDGVPIADDEIILEADGECKIGSGMLLESQQSSSQNHEMDMPSTSMDHYHHQDIDDGGVGDDIEQQVVVGGPSDEMAIQYDEDLAFQQHINSVLNRLSDDEKSVMKFNMQKIILDARFGLGTARNMLKHDEMLEVESHVEIDPNHEVPEEI q86rt3_caeel protein protein caeel Caenorhabditis elegans FEIMIKPLVIIAVLLVNDVVCPPPLRQQAEQAQAQDNVQHQPATGDAQQGQGQAQNTEQQGEYDGRHPGYQFAYTKYLEEVVKILESDPKFNERLKNMKEEDIKAGNIADHIDDLPQEVFDKLHKAKFDEIERLRKQIEEQIKADGGAHNIKMPDHLDVQELEKFHKEDLRKLIQKTVADMNVMDEQRKDDFKQYEMKKQAEEDHKLAQMTPEEREKAKSEHEESLKRHNDHEKLKHPGSKDQLQEVWEESDHLEKDQYDPKTFFALHDLNGDGFWNDFELESLFQLELEKMYNETNPDDDMKERAEEMYRMREHVMKQIDVNQDRMISMQEFLNDSDNQNSNPPKQEEWEDLGQKKVYTDEELQQFEREYAQKQEQQHPQEAVQQPPQAQQQVHPAQQPIQPVNANPPPVQNAQPPVQQQQQPPQQPPQQPPQQNLPPVHHEPIQDHTKDPTYGI dmd_caeel Dystrophin-1 F15D3.1 dys-1 protein protein caeel Caenorhabditis elegans MLFSGASTAKPKKDEKKDKKSDRDPKNELQEWVFVRWANHLLGTERLTDYKSLQDGSNAIFVYQAIIGQTMAVLGNPSDDWPNVLQNIGDSKTNPQEVMEGQQKAVLSAWWQLVQFFWKNNAPVQLREEKLSEAIKQWCIEVMKSYEEIDVYDFTSSFRDGHAFNYLIHSYDRKLINLTKTAEMSAIDRIENAFAVAEKTWNVPRLLNPKDLHSDQLDSHSVLCYLMSLYLAMISTSKIETELEAQQIQQQKVAALLASHKMLSSQPSTSSSSALQIPPQTPPTAHHQAMLDRGKSFEQSAEGEVRSRKSSSSSQKSGKSKKARREEQLAEFKSCIEQVLTWLLEAEDELTTLTQMPRVELASVRSQFSDFESFMSSLTDSQDTVGRVLLRGQMLSNKSESEEEKESIGANLHLVNTRWEALREQAMQEQAVLQQQIHLLQQSELDTISQWLDAAELEIESFGPLAADSSQALRQIELHTKFQQKLNDFQETIDKLESFVAVVDEENDASVATLEDALSAVSVRWGHVCEWAEKRATKLDGLADLLDKTNEVFENLSGWLAERENELMTGLKSAHHLENEEQVAQQVRRLQKTEEQLEQEHASFVRLSQLSCELVGRLDDSNGAAANAVRLSLDSITQRWDNLVARIEEHGKTLVKSGKADVKQVQESQNEQKEQPASSEGLSTDTEGEEQKNQLVDKFLLHISKLSHELEPLQDWSEKFEVSRKKDDIRKMMNTCQEKLIQIKEQEARVNRLQLELEHLHVAKLNARQLKRANDAFEQFAKGWARIVTKISEAMNVLTGQEAGGNGNGSEEAAVAAKIEQWIEAVDKVINELSQLPVNERRSRIDKLEQQLQVQDKNVGFIEKDLLKKAILKKGLEIAGKRLAALKVEEKPVEKEEQLVLSNSEEPEAEKHVTFVQETTEKPAPLQEPTSEAQLLEELDGPWSRVGDVVAIEHDLLRAKRAVDTARNSQMSNETVEKAETRKAEMEEKRRVTMSARSKFRMAEETLEEIERNLDRLQVSDLEIADLVRGLEQEAAKLGERVSQRKEAERTAEKILSMDDDEISQEIVIKTKDSTEKLIKRWNQLELDLEENLRKAKRDQDVFIQKRLREGEEALNEIKTAIEGKRESLDAETAAENLDHLESSLDNISSLFGEIGSLPMDDNSREKLSKLAKAKDQITARANEALAALTRTVSECEDFEKQIMLFQNWSARIGFLLQARKSADISAFDIPHEYHEDLGNEAELIPKLSREFEEWTVKLNEMNSTATEKDDSARMREQLNHANETMAELKRKFNEFKRPKGFEEKLEKVITTLSNVEMGLDDTTGIDGSECGGALMEVRALVRMLDGAQEKWKDLAENREQLVKDRVLDEETSKETLQKLQYAKTKSKELYERSSTCIERLEDCVEMYQRLKMESDEIERFLEEMEGKLDQYAASDRPEEAEIVNELISEWNRNEAAMKNAEHLQRQLNERAIKIPDDVLSLKRLRADALKNRLNSWCRTIQEMSEDDESALLEIDELHQNLEKELKLVSDKEPSKIAEKLRFLRADRDRLSSRTRKLAAKNPRLAATSSDVLAGLNQKWKELEVKASAEKAPAPELRDARLSSPSEQPFDKRVQELCDLFENLEAQLDFNGSPVSMVTEYQKRVENLDEYLDEYRPALDDTIEEGRKIAETGRLELQTHSAIEKLDELTNRIEQVEVELDKHRDKVPSLVEQHEQLKKDIDSFLLVLDVFTDRNLDDVDIAKSTRKELAERDSHIVSLTSRATAIHCALPGKGPQLHDVTLDKLRDRIEKLEARLSATEKKPVETVKSTIPDRPEVPEEPEKSSPDRTSRSSLQLAMEAYGTATEDDSVISEAVTVGQKSVDQVDPVEQLEPVEPVEPKLEVKQLKDEATEEEEKRTIILPDETEKVIETIPAARPSAGPSEGTVAEVSTSEILKARPAQESIERTVREVPVDEYEETANISSGDELQDHKISSAVPDSESEIASMFEVLDSIEDSHTNFEEFPFDYLDSADDDLKKTLLKLESCEKTLAKNEMTINIAQAENARERITMLRQMALQRKDKLPKFNEEWNAMQELIQLADALVDEAERYESDQIPQMDRKSAPNVLGELRKRVANAEGPVIDLVKKLSQLVPRMQEDSPKSQDIRQKVYGIEDRFRRVGQAEGAAISKALSSALTEPELKLELDEVVRWCEMAEKEAAQNVNSLDGDGLEKLDGRLAQFTKELQERKDDMVQLEMAKNMIIPSLKGDAHHDLRRNFSDTAKRVAMVRDELSDAHKWVATSRDTCDTFWADIDSLEQLARDVVRRANGIRMAVIYTPSRENVEGVLRDVQRLKMSIGDVKKRVQTANLPPAIKLAGKNAKRVVQVLTETATTIADCHDIPTYLIDEMNDSGGDTTESRSTVVEMTSVHTKQSSSSSSNKTPSAGGESDDAHTLNGDDEQSEEDQKIYSRESSSTLPRGVSSLGSTGSSGVLDPVAVQLTHTRHWLHDVERDASITVDLAQWQPARELWQSIQGIIDEIRLRSVHVTGAHDASPNRQVRQQAAQLLTEMRRTIENCEKRCLILNQISDIARQNEASRNEMELWLKSASDVIGERRVEELSEEVVRQELQVLERVVEQLTERKDKMAEINSQANKIVDTYTKDEAHNLSHLLSRLNMSWTKFNDNIRIRRAVLEASLRSRRDFHSALSEFEKWLSRQEDNCSKLSADTSNHQAIKDTSKRKNWTQSFKTLNAELNAHEDVMKSVEKMGKMLAESLESGNEKVELLKRVGETTRRWTALRKTTNEIGERLEKAEQEWEKLSDGLADLLSWVEAKKQAIMDEQPTGGSLSAVMQQASFVKGLQREIESKTANYKSTVEEAHSFLMQHDLRPKLHSPHVLDDDYEKEELANLEQRRRGLEINANCERLKKNWAELGIEVESWDKLVQHAMQRLQELERNLAECQLHLTSSENEIETMKAVEKIHLEDLKIAREETDQISKRIDEVRLFVDDVNDAAARLLAEDLKLDEHAKGQIEHVNKRYSTLKRAIRIRQAAVRNAASDFGPTSEHFLNQSVTLPWQRAISKSNLLPYYIEQTSEKTQWEHPVWVEIVKELSQFNRVKFLAYRTAMKLRALQKRLCLDLVDLTLLEKAFVRLKGLSAEECPGLEGMVCALLPMYEALHAKYPNQVQSVSLAVDICINFLLNLFDQSRDGIMRVLSFKIAMIVFSNIPLEEKYRYLFKLVSQDGHATQKQIALLLYDLIHIPRLVGESAAFGGTNVEPSVRSCFETVRLAPTISEGAFIDWVKKEPQSIVWLAVMHRLVISESTKHASKCNVCKMFPIIGIRYRCLTCFNCDLCQNCFFSQRTAKSHRTNHPMQEYCEKTTSSDDARDFAKMIRNKFRASKRQKGYLPIDVAEEGIPLTCPPAKVTNQATEQMNADTSQMTAHLAKLSAEHGGGAEHMEPVQSPLQIINQVEQLQRDEMDQMLHRLQFENKQLRKELEWKRGAASTMEIDRSSKRHQERHQSESRGGTLPLRNGRSVVSLKSTQSQNDVMDEAKALRLHKQRLEHRSRILEQQNEQLEMQLQRLKKVIDAQKQQAPLSTNSLLRGSHHQPWSPERARSGSASTLDRGLIVSSRHQEQAEAAGGGAEDSSDEAGGAGGGPRGSSVGQMQNLMTACDDLGKAMESLVVSVVYDSDDEEND gpa_7-nhr22-1 1284528 n/a 1284530 unspecified role unspecified role prey prey n/a 1284531 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 gpa_13-1 1284528 n/a 1284532 unspecified role unspecified role prey prey n/a 1284533 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GPA-13. gpa_6-q86rt0-1 1284528 n/a 1284534 unspecified role unspecified role bait bait n/a 1284535 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 q86rt0-nhr_22 1284528 n/a 1284530 unspecified role unspecified role prey prey n/a 1284535 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 gpa_13-nhr_114 1284528 n/a 1284532 unspecified role unspecified role prey prey n/a 1284533 unspecified role unspecified role bait bait Q9XTB2:p.Gln205Leu mutation mutation certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GPA-13. The mutation has been entered for the GPA-13 constitutively active GTPase-deficient mutant as "gln205leu" - as the most likely mutation site, because the actual mutation site is not stated in this paper. gpa_7-nhr_22 1284528 n/a 1284531 unspecified role unspecified role bait bait Q21917:p.Gln203Leu mutation mutation certain certain sequence position certain certain certain sequence position certain false n/a 1284530 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GPA-7. goa_1-rapgap-1 1284528 n/a 1284536 unspecified role unspecified role bait bait n/a 1284537 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 goa_1-f32a6.4-1 1284528 n/a 1284538 unspecified role unspecified role prey prey n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 goa_1-f59h5.1-1 1284528 n/a 1284539 unspecified role unspecified role prey prey n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 goa_1-c01h6.9-1 1284528 n/a 1284536 unspecified role unspecified role bait bait n/a 1284540 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 goa_1-lin36-1 1284528 n/a 1284536 unspecified role unspecified role bait bait n/a 1284541 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 goa_1-q86rt5-1 1284528 n/a 1284542 unspecified role unspecified role prey prey n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 goa_1-q86rs9-1 1284528 n/a 1284543 unspecified role unspecified role prey prey n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 rapgap-goa_1 1284528 n/a 1284537 unspecified role unspecified role bait bait n/a 1284536 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GOA-1. ags_3-goa_1 1284528 n/a 1284536 unspecified role unspecified role prey prey n/a 1284538 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GOA-1. q9tzi4-goa_1 1284528 n/a 1284536 unspecified role unspecified role prey prey n/a 1284539 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 lin_36-goa_1 1284528 n/a 1284541 unspecified role unspecified role bait bait n/a 1284536 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 lin_36-lin36 1284528 n/a 1284541 unspecified role unspecified role bait bait n/a 1284541 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 q86rs9-q86rs9 1284528 n/a 1284537 unspecified role unspecified role prey prey n/a 1284537 unspecified role unspecified role bait bait physical association physical association false false false Fig 1 goa_1ql-ags_3 1284528 n/a 1284536 unspecified role unspecified role bait bait P51875:p.Gln205Leu mutation mutation certain certain sequence position certain certain certain sequence position certain false n/a 1284538 unspecified role unspecified role prey prey physical association physical association false false false Fig 1 Only two (AGS3.1 and Rap1GAP) out of the seven candidates, interact with the constitutively active GTPase-deficient mutant of GOA-1, as Bait. goa_1-rapgap 1284528 n/a 1284537 unspecified role unspecified role prey prey n/a 1284536 unspecified role unspecified role bait bait P51875:p.Gln205Leu mutation mutation certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig 1 Only two (AGS3.1 and Rap1GAP) out of the seven candidates, interact with the constitutively active GTPase-deficient mutant of GOA-1, as Bait. gpa_6-q86rt0 1284529 n/a 1284534 unspecified role unspecified role bait bait n/a 1284535 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain undetermined undetermined sequence position undetermined false physical association physical association false false false Table 2 gpa_7-nhr22 1284529 n/a 1284530 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1284531 unspecified role unspecified role bait bait physical association physical association false false false Table 2 gpa_13 1284529 n/a 1284533 unspecified role unspecified role bait bait n/a 1284532 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 2 gpa_13-dys1 1284529 n/a 1284544 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1284533 unspecified role unspecified role bait bait physical association physical association false false false Table 2 goa_1-q86rt5 1284529 n/a 1284542 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Table 2 goa_1-c01h6.9 1284529 n/a 1284536 unspecified role unspecified role bait bait n/a 1284540 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 2 goa_1-lin36 1284529 n/a 1284541 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Table 2 goa_1-f59h5.1 1284529 n/a 1284539 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1284536 unspecified role unspecified role bait bait physical association physical association false false false Table 2 goa_1-f32a6.4 1284529 n/a 1284536 unspecified role unspecified role bait bait n/a 1284538 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 2 goa_1-rapgap 1284529 n/a 1284536 unspecified role unspecified role bait bait n/a 1284537 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 2 goa_1-q86rs9 1284529 n/a 1284536 unspecified role unspecified role bait bait n/a 1284543 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 2