mpidb The Microbial Protein Interaction Database kutter-2008-1 Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Kutter S., Buhrdorf R., Haas J., Schneider-Brachert W., Haas R., Fischer W. J. Bacteriol. (0021-9193) 2008 Only protein-protein interactions imex curation kutter-2008-2 Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. helpy Helicobacter pylori Campylobacter pylori anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kutter S., Buhrdorf R., Haas J., Schneider-Brachert W., Haas R., Fischer W. J. Bacteriol. (0021-9193) 2008 Only protein-protein interactions imex curation e0whx5_helpx Type IV secretion system protein D2C88_07850 F7214_07700 G3M67_01650 G3M68_02165 virB11 BB390_07385 BB399_06580 BB400_06565 BB408_03415 BB409_06940 BB413_00305 BB414_01925 BB425_07095 BB432_04770 BB447_03415 BB457_02875 BB458_07415 BB459_01845 D2C71_01285 D2C72_01830 D2C73_05755 D2C77_01800 D2C79_04640 D2C81_06585 D2C82_03020 D2C83_06175 D2C87_02690 G3M69_06130 EPC73_04595 EPC76_07865 EPC81_06110 EPC84_06070 B0X24_06635 B0X38_06500 B0X41_06920 B0X44_06825 B0X46_00385 B0X55_08345 B0X66_06525 cagAlpha BB456_03380 BB450_01410 BB464_01490 NCTC13094_00155 BB465_01035 DD741_03450 DD763_02555 DD767_02220 DD773_01955 DD774_02235 DD776_02915 DD794_03195 BB467_03295 BB468_07040 BB479_00320 BB482_02255 BB483_03555 BCM300_00547 BGL56_08125 BGL58_06750 BGL61_01890 BGL62_00535 BGL69_06470 BGL71_04855 BGL73_03525 BGL83_04980 BGL85_01790 BZK17_00420 BZK18_00380 BZK20_03360 BZK22_01120 BZK23_01125 BZK25_05690 BZK27_07230 C2R50_00720 C2R69_03570 C2R71_01915 C2R76_06890 C2R81_06955 C2R88_00960 C2R92_04375 HP0525 HP525 HPY1198_03775 cagalpha F7190_06260 F7195_05360 F7212_07765 EGW01_00990 EC516_05795 EC549_02620 D2C86_05370 F7204_05345 EGV97_03120 F7221_05960 F7223_05905 F7209_03795 protein protein helpx Helicobacter pylori Campylobacter pylori MTEDRLSAEDKKFLEVERALKEAALNPLRHATEELFGDFLKMENITEICYNGDKVVWVLKNNGEWQPFDVRNKKAFSLSRLMHFARCCASFKKKTIDNYENPILSSNLANGERVQIVLSPVTVNDETISISIRIPSKTTYPHSFFEEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKTTYIKSIMEFIPKEERIISIEDTEEIVFKHHKNYTQLFFGGNITSADCLKSCLRMRPDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLANMSSSNSAARNIKFESLIEGFKDLIDIIVHINHHKQCDEFYIKHR caga_helpy Cytotoxicity-associated immunodominant antigen 120 kDa protein CAG pathogenicity island protein 26 cai HP_0547 cagA cag26 protein protein helpy Helicobacter pylori Campylobacter pylori MTNETIDQTRTPDQTQSQTAFDPQQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFIFNKKQSSDVKEAINQEPVPHVQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYAGNGGFGDKHDWNATVGYKDQQGNNVATLINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRNKVDFMEFLAQNNTKLDNLSEKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFNNGDLSYTLKDYGKKADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLEAGFNKVAVFNLPDLNNLAITSFVRRNLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKRELSDKLEKISKDLKDFSKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSVAKAMGDFSRVEQVLADLKNFSKEQLAQQAQKNEDFNTGKNSELYQSVKNSVNKTLVGNGLSGIEATALAKNFSDIKKELNEKFKNFNNNNNGLKNSTEPIYAKVNKKKTGQVASPEEPIYTQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKRHDKVDDLSKVGLSASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDKLKDSTKKNVMNLYVESAKKVPASLSAKLDNYAINSHTRINSNIQNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVSLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDIKSGFTHFLANAFSTGYYCLARENAEHGIKNVNTKGGFQKS e0wih3_helpx cagY HP0527 protein protein helpx Helicobacter pylori Campylobacter pylori MNEENDKLETSKKTQQHSPQDLSNEETTEANHFEDSSKESKESSDHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEDDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETTEANHFEDSSKESKESSDHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEDDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETTEANRFEDSSKESKESSDHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEYDQENNGYQEETQMDLIDDEASKKTQQHSPQDLSNEETTKANRFEDSSKESKESSDHHLDNSTETKTNFDGEKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESVKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSKARNEKEKKECEKLLTPEARKKLEEAKKSVKAYLDCVSQARTEAEKKECEKLLTPEARKLLEQEALDCLKNAKTEAEKKKCIKDLPKDLQKKVLAKKSVKAYLDCVSQARTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQARTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSRARNEKEKKECEKLLTPEAKKKLEEAKKSVKAYLDCISQAKTEAEKKECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEARKFLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSRARNEREKQECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKQVLSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSGLIQEIQNKRTQSKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERVLILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKSGEFVDENGNPIDDKKKAEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVVASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN e0wi26_helpx cagF HP543 protein protein helpx Helicobacter pylori Campylobacter pylori MKQSLREQKLLKILENDVLTILDSFSNYLFELKEELDFIEEEMEGEITEQNLTALYDFSNFLEDHVNVFYENVLNIDDVKTEHLYSGLIDSLNANLHFVKSFLSNQDLDFRFFKEINDGQDPQKTLSRLIPLQSGKNDANSFKANNSFVSLVYVYAYFMLETIKQSYRILRLLEKPINNNISEDMQSDIENFFVQANFLEYYVQNKIYPTNHAYDFTHLIMDSIIPNWIQIDMSVEAKKKELFEKYFQNIDEVTNKMLDQENQNKNSD a4gmu0_helpx HP0528 cag8 protein protein helpx Helicobacter pylori Campylobacter pylori MEQAFFKKIVNCFCLGYLFLSGVIEAAPDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWNIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEETIKQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK e0wk28_helpx cagBeta HP524 protein protein helpx Helicobacter pylori Campylobacter pylori MEDFLYNTLYFIENYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQAILLLSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITFFVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPTRSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVYIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQIDTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNERDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTMFFIGSMASGINLIDENTNMEKVVSLMEFFGGEEDKSGDNLKVLSPATRNMWNNFKTMGGARETYSSVQGVYTSAFAPYNNAMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLETFVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRSIDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQATFYDDLQAAKTRGELSYDKSLVPVGSSEL e0wi24_helpx cagH HP541 protein protein helpx Helicobacter pylori Campylobacter pylori MAGTQAIYESSSAGFLSEISSIISSTSGVAGPFAGIVAGAMSAAIIPIVVGFTNPQMTAIMTQYNQSIAEAVSMPMKAANQQYNQLYQGFNDQSMAVGNNILNISKLTGEFNAQGNTQSAQIGAVNSQIASILASNTTPKNPSAIEAYATNQIAVPSVPTTVEMMSGILGNITSAAPKYALALQEQLRSQASNSSMNNTADSLDSCTALGALVGSSKVFFSCMQISMTPMSVSMPTVYAKYQALATNALTSGVNPMTTPACPIGDKVLAVYCYAEKVAEILREYYIEFVKNNTNLLQNASQMILGQSGLATSTYDTQAISNISSLYNYNIIANKSFLKSHLTYLDYIKDKLKGQKDSYLTERVQTKIIVK a0fds9_helpx HP0539 cag18 AEY55_04700 CV726_04970 NCTC12823_00667 protein protein helpx Helicobacter pylori Campylobacter pylori MKTLVKNTISSFLLLSVLMAEDITSGLKQLDNTYKETNQQVLKNLDEIFSTTSPSANNEIGQEDALNIKKAAIALRGDLALLKANFEANELFFISEDVIFKTYMSSPELLLTYMKINPLDQNTAEQQCGISDKVLVLYCEGKLKIEQEKQNIRERLETSLKAYQSNIGGTASLITASQTLVESLKNKNFIKGIRKLMLAHNKVFLNYLEELDALERSLEQSKRQYLQERQSSKIIVK a0fds8_helpx HP0537 cag16 cagM AEY52_04155 AEY53_01525 ECC33_03325 protein protein helpx Helicobacter pylori Campylobacter pylori MLAKIVFSSLVAFGVLSANVEQFGSFFNEIKKEQEEVAAKEDALKARKKLLNNTHDFLEDLVFRKQKIKELMDHRAKVLSDLENKYKKEKEALEKETRGKILTAKSKAYGDLEQALKDNPLYKKLLPNPYAYVLNQETFTKEDKERLSYYYPQVKTSSIFKKTTATTKDKAQALLQMGVFSLDEEQNKKASRLALSYKQAIEEYSNNVSNLLSRKELDNIDYYLQLERNKFDSKAKDIAQKATNTLIFNSERLAFSMAIDKINEKYLRGYEAFSNLLKNVKDDVELNTLTKNFTNQKLSFAQKQKLCLLVLDSFNFDTQSKKSILKKTNEYNIFVDSDPMMHDKTTMQKEHYKIFNFFKTVVSAYRNNVAKNNPFE e0wi15_helpx cagT HP532 protein protein helpx Helicobacter pylori Campylobacter pylori MKLRASVLIGVAILCLILSACSNYAKKVVKQKNHVYTPVYNELIEKYSEIPLNDKLKDTPFMVQVKLPNYKDYLLDNKQVVLTFKLVHHSKKITLIGDANKILQYKNYFQANGARSDIDFYLQPTLNQKGVVMIASNYNDNPNNKEQPQTFDVLQGSQPMLGANTKNLHGYDVSGANNKQVINEVAREKAQLEKINQYYKTLLQDKEQEYTTRKNNQREILETLSNRAGYQMRQNVISSEIFKNGNLNMQTREEEVREKLQEERENEYLRNQIRSLLSGK e0wi14_helpx D2C82_03050 BGL56_05570 cagU HP531 protein protein helpx Helicobacter pylori Campylobacter pylori MNDTTEHHGSNPLNAPPPSNSQSNDLLNLLDSLYPKGSLGEQRFHEALKNQEELKNILIEIEKLPQEKRYELLMQIGQAKQRIMEAYAHSFLGYIGGLEHLLGLCMGGIFVLFAIYFVFLRTSKNTELVESLKTRLKLQYFYYAFGVGAVLFFGLETIRSIYELYILGIGSTNDKVLFVLKNICFIGMGYLIYKVIKVIGIKNFINGLFASKKQGGAE e0wi21_helpx cagN HP538 protein protein helpx Helicobacter pylori Campylobacter pylori MKSIFKKLGSVALYSLVIYGGLNAINTALLPSEYKKLVALGFKKITTLYQRHDDKEITKEEKEFATNALREKLRNDRARAEQIQKNIEAFEKKNNSSVQKKAAKHRGLQELNETNANPLNDNPNGNSPTETKSNKDDNFDEMINKVNESFVKPADPLVPDKWRTPEIEIIINECIISSNDYDGLRKCLIKDIKDQKILAPLLEKIQEIETENNKFSRQHLSGLKLALNNSNNRTFLIASCAICEKRKKEMEQENNYQDTTNASEFGATDTKENEAKDATSSNNRSKSELPNSVINQIEQSIAHGKNSDPNY e0wif9_helpx cagV HP0530 HP530 EC548_05175 protein protein helpx Helicobacter pylori Campylobacter pylori MLGKKNEEVLIDENLVGGVIALDRLAKLNKANRTFKRAFYLSMALNIAAVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSDARQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQFVDKVRAEAIISSNIQREKVKNSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFARGNSSQENLIINPFGFKVFDIQITDLQNEQTVSEILRKIKEVESKNKALKK e0wif7_helpx cagX HP0528 HP528 protein protein helpx Helicobacter pylori Campylobacter pylori MEQAFFKKIVGCFCLGYLFLSSVIEAAAPDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEETVKQRAKDKINIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEGELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK e0wk31_helpx cagY HP527 protein protein helpx Helicobacter pylori Campylobacter pylori MNEENDKLETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSDHHLDNSTETETNFDGDKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEYDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSDHHLDNSTETETNFDGDKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEYDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSDHHLDNSTETETNFDEYKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQNDILAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQARTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECGKLLTPEARKLLEQQVLDCLKSAKTDEERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKNEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSRARNEKEKKECEKLLTPEARKLLEEAKESLKAYKDCLSQARNEEERKACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKQVLSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYKNCLSQARNEEERKACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKRTQSKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKSGEFVDENGNPIDDKKKTEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPVMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN cagalpha-cagalpha 1332851 n/a 1332853 unspecified role unspecified role bait bait n/a 1332853 unspecified role unspecified role prey prey physical association physical association false false false Table 2 caga-cagy 1332851 not-defined-567218194 1332854 unspecified role unspecified role bait bait n/a 1332855 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 caga-cag22-1 1332851 n/a 1332856 unspecified role unspecified role prey prey not-defined-849041031 1332854 unspecified role unspecified role bait bait physical association physical association false false false Table 2 cag22-cagf-1 1332851 n/a 1332856 unspecified role unspecified role bait bait not-defined-2093807934 1332857 unspecified role unspecified role prey prey physical association physical association false false false Table 2 cag22-cagf 1332851 not-defined-1112705315 1332854 unspecified role unspecified role prey prey n/a 1332856 unspecified role unspecified role bait bait physical association physical association false false false Table 2 cagh-cagbeta 1332851 n/a 1332858 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332859 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false 1332888 1332886 physical association physical association false false false Table 2 cag18-cagbeta 1332851 n/a 1332858 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false not-defined-146799938 1332860 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false 1332893 1332891 physical association physical association false false false Table 2 cag16-cag16 1332851 not-defined-1555216370 1332861 unspecified role unspecified role bait bait not-defined-1730753775 1332861 unspecified role unspecified role prey prey physical association physical association false false false Table 2 cag12-cagt 1332851 n/a 1332862 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332858 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 cagu-caga 1332851 not-defined-478168965 1332854 unspecified role unspecified role prey prey n/a 1332863 unspecified role unspecified role bait bait physical association physical association false false false Table 2 cag10-cagv 1332851 n/a 1332864 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332865 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false 1332909 1332907 physical association physical association false false false Table 2 cag8-cagx 1332851 n/a 1332866 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false not-defined-741116052 1332861 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false 1332914 1332912 physical association physical association false false false Table 2 cag16-cagx 1332851 n/a 1332866 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false not-defined-741116052 1332861 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 cag7-cagf 1332851 n/a 1332856 unspecified role unspecified role bait bait n/a 1332855 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 caga-caga 1332851 n/a 1332854 unspecified role unspecified role prey prey n/a 1332854 unspecified role unspecified role bait bait physical association physical association false false false Table 2 cagbeta-cagy-3 1332851 n/a 1332855 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332858 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 cagy-cagf 1332851 n/a 1332856 unspecified role unspecified role prey prey n/a 1332855 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 cagy-cagn 1332851 n/a 1332855 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332864 unspecified role unspecified role prey prey physical association physical association false false false Table 2 cagy-cagy 1332851 n/a 1332855 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332855 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false 1332944 1332942 physical association physical association false false false Table 2 cagy-cagy-1 1332851 n/a 1332855 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1332855 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false 1332949 1332947 physical association physical association false false false Table 2 cagn-cagy 1332851 n/a 1332864 unspecified role unspecified role bait bait n/a 1332855 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 2 cagx-cag16 1332852 n/a 1332867 unspecified role unspecified role prey prey n/a 1332866 unspecified role unspecified role bait bait n/a 1332862 unspecified role unspecified role prey prey n/a 1332861 unspecified role unspecified role prey prey association association false false false Fig 6A cagy-cag16 1332852 n/a 1332862 unspecified role unspecified role prey prey n/a 1332866 unspecified role unspecified role prey prey n/a 1332867 unspecified role unspecified role bait bait n/a 1332861 unspecified role unspecified role prey prey association association false false false Fig 6B cag16-cagt 1332852 n/a 1332866 unspecified role unspecified role prey prey n/a 1332862 unspecified role unspecified role prey prey n/a 1332867 unspecified role unspecified role prey prey n/a 1332861 unspecified role unspecified role bait bait association association false false false Fig 6C cag16-cagx-1 1332852 n/a 1332866 unspecified role unspecified role prey prey n/a 1332861 unspecified role unspecified role bait bait physical association physical association false false false Fig 7A Interaction observed in CagT and CagY -/- cells cagx-cag16-1 1332852 n/a 1332866 unspecified role unspecified role bait bait n/a 1332861 unspecified role unspecified role prey prey physical association physical association false false false Fig 7A Interaction observed in CagT and CagY -/- cells cagx-cag16-2 1332852 n/a 1332867 unspecified role unspecified role prey prey n/a 1332866 unspecified role unspecified role bait bait physical association physical association false false false Fig 7B Interaction observed in CagM and CagT -/- cells cagy-cagx 1332852 n/a 1332866 unspecified role unspecified role prey prey n/a 1332867 unspecified role unspecified role bait bait physical association physical association false false false Fig 7B Interaction observed in CagM and CagT -/- cells cag16-cagy 1332852 n/a 1332866 unspecified role unspecified role ancillary ancillary n/a 1332867 unspecified role unspecified role prey prey n/a 1332861 unspecified role unspecified role bait bait association association false false false Fig 7C cag16-cagt-1 1332852 n/a 1332862 unspecified role unspecified role prey prey n/a 1332861 unspecified role unspecified role bait bait physical association physical association false false false Fig 7D Interaction observed in CagX and CagY -/- cells cagx-cagt 1332852 n/a 1332862 unspecified role unspecified role prey prey n/a 1332866 unspecified role unspecified role bait bait n/a 1332861 unspecified role unspecified role ancillary ancillary association association false false false Fig 7E