IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ rosenkranz-2006-1 Functional association of the AAA complex and the peroxisomal importomer. yeast Saccharomyces cerevisiae Baker's yeast pull down pull down western blot western blot Immuno blot Immuno blot Rosenkranz K., Birschmann I., Grunau S., Girzalsky W., Kunau W.H., Erdmann R. Ralf.Erdmann@rub.de FEBS J. (1742-464X) 2006 Only protein-protein interactions imex curation rosenkranz-2006-2 Functional association of the AAA complex and the peroxisomal importomer. yeast Saccharomyces cerevisiae Baker's yeast bn-page blue native page bn-page western blot western blot Immuno blot Immuno blot Rosenkranz K., Birschmann I., Grunau S., Girzalsky W., Kunau W.H., Erdmann R. Complexes isolated by anti-protein A pull down, 2D separation - the second dimension was SDS-PAGE Ralf.Erdmann@rub.de FEBS J. (1742-464X) 2006 Only protein-protein interactions imex curation rosenkranz-2006-3 Functional association of the AAA complex and the peroxisomal importomer. yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Rosenkranz K., Birschmann I., Grunau S., Girzalsky W., Kunau W.H., Erdmann R. 2D separation - the second dimension was SDS-PAGE Ralf.Erdmann@rub.de FEBS J. (1742-464X) 2006 Only protein-protein interactions imex curation pex6_yeast Peroxisomal ATPase PEX6 PEX6 PAS8 YNL329C N0310 Peroxin-6 Peroxisome biosynthesis protein PAS8 Peroxisomal assembly protein 8 protein protein yeast Saccharomyces cerevisiae Baker's yeast MKASLTFSLSGIYAPCSISRDIYLEYGDKKAECLYGTIRLPQYGPGCTPGKIVHCVLDDSLPFCSIVVPSKLFGFMPTQPTMDFCYFEPILDNVVPVLDSVTFLINEQLYSKLMDLPQEMQQIQFLHYKYNINSMETVVHSRDILTSGLCQILNCSPFPQGLVDFTETQLILVNDTEQKLSALKYANEDEEYALPKIGTNSALSIDLESLPCTISRDLLRPAPHINDDNSIYAFTDAETLLRLDVTSGSFITVSNMGCVRLVKLFVLLLPNGFKKRTIYAPPKIIASFPDCSVVTISKSNIGHTDIPIANQVFISRVGGWLQSQKCFQNIILTTLKKFFSESKRILCQNDLIPIAFDSSMADLNIAEENDESDDEDELGQYYKNDSLVWFFVTSAELDCFSKDNSHFIIDPNRTKLITTNITNRRPLPLSRSNLQRYYGFAETFYYDLHIFPYVRQLVNILETSFNCSQRGITLNASVLLHSTTNNVGKATMVRFASKYLGIHLLEIDCLSLTSNSRQLDSTSKIIGYIRAKCENVLPYASPAVIFLAHLDSILLDVNANQDPEAIKLQKSINFEMSKLLDDFTFKFPGTTFVGSVNNIDNVPSSFRSHMRFEILVPVPSEAQRLRIFQWYLSSHELNRDVQQKVPVSYMDNISFSSLSSYSAGLTPLDIKSIVETARMTATARFYQESKKCGWLPQSILITQEDLSKATSKARNEFSVSIGAPQIPNVTWDDIGGIDFVKGEILDTIDMPLKHPELFTSGMKKRSGILFYGPPGTGKTLMAKAIATNFSLNFFSVKGPELLNMYIGESEANVRRVFQKAREAKPCVIFFDEIDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSTDADGVFVIGATNRPDLLDEALLRPGRFDKLLYLGIPDTDTKQLNILEALTRKFVLDNDVKLIELAKLCPFNYTGADFYALCSDAMLNAMSRIARMVEKKVSQHNELTGENISTRRWFDKIATKEDTKVVVKMEDFLKAQEQLTPSVSRAELNHYEAVRANFEGA 736FECB57BBFF8F8 pex1_yeast Peroxisomal ATPase PEX1 YKL197C PEX1 PAS1 Peroxin-1 Peroxisome biogenesis protein PAS1 Peroxisomal assembly protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQEFGIAVHSHNSDIPIVHLGWDGHDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYDHTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEGIVTKFKIDRVEPSMKSARITDGSLVVVAPKVNKTRLVKAEYGHSNKTILKNGAIQLLKKVILRSTVCKMDFPKDNLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIGVFIKCDSQIPENHIALSSHLWDAFFTHPMNGAKIKLEFLQMNQANIISGRNATVNIKYFGKDVPTKSGDQYSKLLGGSLLTNNLILPTEQIIIEIKKGESEQQLCNLNEISNESVQWKVTQMGKEEVKDIIERHLPKHYHVKETGEVSRTSKDEDDFITVNSIKKEMVNYLTSPIIATPAIILDGKQGIGKTRLLKELINEVEKDHHIFVKYADCETLHETSNLDKTQKLIMEWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFNKDNKRIRVLFSGKQKTQINPLLFDKHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKLNRDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDNVVTRELFSKSLSAFTPSALRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRLDKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQGLCYNAYLKSVHRWLSAADQSEVVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVHETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNGENSIDIGSRLSLM pex5_yeast Peroxisomal targeting signal receptor PEX5 PAS10 YDR244W YD8419.11 Peroxisomal protein PAS10 Peroxin-5 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDVGSCSVGNNPLAQLHKHTQQNKSLQFNQKNNGRLNESPLQGTNKPGISEAFISNVNAISQENMANMQRFINGEPLIDDKRRMEIGPSSGRLPPFSNVHSLQTSANPTQIKGVNDISHWSQEFQGSNSIQNRNADTGNSEKAWQRGSTTASSRFQYPNTMMNNYAYASMNSLSGSRLQSPAFMNQQQSGRSKEGVNEQEQQPWTDQFEKLEKEVSENLDINDEIEKEENVSEVEQNKPETVEKEEGVYGDQYQSDFQEVWDSIHKDAEEVLPSELVNDDLNLGEDYLKYLGGRVNGNIEYAFQSNNEYFNNPNAYKIGCLLMENGAKLSEAALAFEAAVKEKPDHVDAWLRLGLVQTQNEKELNGISALEECLKLDPKNLEAMKTLAISYINEGYDMSAFTMLDKWAETKYPEIWSRIKQQDDKFQKEKGFTHIDMNAHITKQFLQLANNLSTIDPEIQLCLGLLFYTKDDFDKTIDCFESALRVNPNDELMWNRLGASLANSNRSEEAIQAYHRALQLKPSFVRARYNLAVSSMNIGCFKEAAGYLLSVLSMHEVNTNNKKGDVGSLLNTYNDTVIETLKRVFIAMNRDDLLQEVKPGMDLKRFKGEFSF pex14_yeast Peroxisomal membrane protein PEX14 PEX14 YGL153W G1870 Peroxin-14 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSDVVSKDRKALFDSAVSFLKDESIKDAPLLKKIEFLKSKGLTEKEIEIAMKEPKKDGIVGDEVSKKIGSTENRASQDMYLYEAMPPTLPHRDWKDYFVMATATAGLLYGAYEVTRRYVIPNILPEAKSKLEGDKKEIDDQFSKIDTVLNAIEAEQAEFRKKESETLKELSDTIAELKQALVQTTRSREKIEDEFRIVKLEVVNMQNTIDKFVSDNDGMQELNNIQKEMESLKSLMNNRMESGNAQDNRLFSISPNGIPGIDTIPSASEILAKMGMQEESDKEKENGSDANKDDNAVPAWKKAREQTIDSNASIPEWQKNTAANEISVPDWQNGQVEDSIP B714D7DA045E2DCB pex15_yeast Peroxisomal membrane protein PEX15 Peroxisome biosynthesis protein PAS21 PEX15 Peroxin-15 PAS21 YOL044W protein protein yeast Saccharomyces cerevisiae Baker's yeast MAASEIMNNLPMHSLDSSLRDLLNDDLFIESDESTKSVNDQRSEVFQECVNLFIKRDIKDCLEKMSEVGFIDITVFKSNPMILDLFVSACDIMPSFTKLGLTLQSEILNIFTLDTPQCIETRKIILGDLSKLLVINKFFRCCIKVIQFNLTDHTEQEEKTLELESIMSDFIFVYITKMRTTIDVVGLQELIEIFIFQVKVKLHHKKPSPNMYWALCKTLPKLSPTLKGLYLSKDVSIEDAILNSIDNKIQKDKAKSKGKQRGVKQKIHHFHEPMLHNSSEEQVKVEDAFNQRTSTDSRLQSTGTAPRKKNNDITVLAGSFWAVLKHHFTRSVLNKNGLLLTGLLLLLCLKKYKSLMAIFKHVPAAFHTVYPQIVGLLKLLASI B575A8D4B0DAC0B8 pex13_yeast Peroxisomal membrane protein PAS20 PEX13 PAS20 YLR191W L9470.1 Peroxin-13 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSSTAVPRPKPWETSASLEEPQRNAQSLSAMMTSNQQDSRPTEESNNSNSASESAPEVLPRPAALNSSGTYGESNTIPGIYGNSNYGIPYDNNPYSMNSIYGNSIGRYGYGGSYYGNNYGSFYGGGYGAGAGYGMNNGSGLGESTKATFQLIESLIGAVTGFAQMLESTYMATHNSFFTMISVAEQFGNLKEMLGSFFGIFAIMKFLKKILYRATKGRLGIPPKNFAESEGSKNKLIEDFQKFNDSGTINSNEKATRRKISWKPLLFFLMAVFGFPYLLNKFITKLQTSGTIRASQGNGSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEIIKRRKKIEHVDDETRTH DBEA9A2372185860 pex17_yeast Peroxisomal membrane protein PEX17 PEX17 PAS9 YNL214W N1319 Peroxin-17 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTSINSFPRNIDWPSNIGIKKIEGTNPTVNAIKGLLYNGGSIYAFLYFVIAMFVEPTLQKQYQQRNDFSLFVLLRLRRIIAQLQKRLVMTPVSSLGFNEQNNFVERSTQTSDDNIIREDNSHWAEMIYQLQNMKQELQYFNRSSGQPSESIDDFVFQIKMVTDQVELTDRSRAFSNKSRNIIQGIREIKGWFVNGQVPR pex8_yeast Peroxisomal biogenesis factor 8 YGR077C PEX8 PAS6 Peroxin-8 Peroxisomal protein PAS6 protein protein yeast Saccharomyces cerevisiae Baker's yeast MFDHDVEYLITALSSETRIQYDQRLLDEIAANVVYYVPRVKSPDTLYRLVGALFRSQFIVQLPPLRLLHIVKDVFLWKLEVSEPTLPISKFYLVWNAVFESHRATWNLSQLMVLDGVLVTYPSFKQLNNAYFIDESSNKTALYYRNWKLQLFSPIWAQLWNTAIVRANLSIQHCLLIALALLFNQSNRSALLHGVDVSWNLVTEKLLDLLEEYVHGIVQPMEIFSTDSVLSTNLNHLASCLTSSITRSNEATLVNSVRKLERICRYLSDTVASLKEQQLDFKFQNVFILIILALKELSAMNMTILPNHKDTFYSMICLSLFHVHVLTQKIGTVGFPSYDYVYDNLVTYFIVMDDLSKITTVLELMKRNNTKQDPNKLVFYINFLNKITNYYGCRIRLPFITEFIEPLLHFDVFFSGKTGNTLDIEIKESIHTLTITVLSIDSSYSSQVAQWQVSRILVYLKMSMDQFIAGKLSANQILLIFGHLSTQLPSLHNYNKHLLRDSLHETYIRIVNVKNPEKKNVLIECLIVQIAFINNPHHLIGWLNICLQLINTHNKKLLQQLWEMVSSLESSLAIDWWYTTVLSSQSSKL pex10_yeast Peroxisome biogenesis factor 10 PAS4 YDR265W D9954.8 PEX10 Peroxin-10 Peroxisome assembly protein 10 Peroxisomal biogenesis factor 10 protein protein yeast Saccharomyces cerevisiae Baker's yeast MKNDNKLQKEALMRLSQLRFPFADAPSIVQAHQKDEQIQGLLIMKVTELCKLIKSQLFVNSYPKELSIFAKLLYLLFTTGRRGRTLGEEYVDLTYTNRKGTRLAGRLKMIVFAFAYPLCPYFITKLYKKIMKNNKESKIEDTESVAAFCKGLLDFILDVHMTLFYFKGAFYSISKRIFGMRYVFKHILSKNEANFREEGSQKYKVLGYILLAQNVMKWYPVLTSTLGSWIYGRKRTNDSITRSSVGLQERSEHESIEGIPKESQLTHINLSDKNQLPFIPEASRKCILCLMNMSDPSCAPCGHLFCWSCLMSWCKERPECPLCRQHCQPQEILVLRQ pex1-pex6-5 1287395 n/a 1287398 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 1A, 1B Low levels of PEX5 were also observed. pex6-pex1-3 1287395 n/a 1287399 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 1A pex1-pex13 1287395 n/a 1287400 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287401 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey association association false false false Fig. 1B pex1-pex10 1287395 n/a 1287404 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287402 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287405 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287398 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287406 unspecified role unspecified role prey prey association association false false false Fig. 3A pex6-pex1-1 1287395 n/a 1287406 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287404 unspecified role unspecified role prey prey n/a 1287405 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287402 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287400 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey association association false false false Figs. 3A pex15-pex1-1 1287395 n/a 1287404 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287405 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287400 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role prey prey n/a 1287406 unspecified role unspecified role prey prey association association false false false Fig. 3A pex15-pex10-1 1287395 n/a 1287400 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287404 unspecified role unspecified role prey prey n/a 1287406 unspecified role unspecified role prey prey association association false false false Fig. 4 Pulldown performed in PEX1-/- cells. pex15-pex10 1287395 n/a 1287406 unspecified role unspecified role prey prey n/a 1287404 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 4 Pulldown performed in PEX6-/- cells. pex6-pex1-1 1287395 n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287400 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey association association false false false Figs. 5A Observed in PEX13-/- cells. Levels of PEX5 and PEX14 are very low. pex15-pex1-2 1287395 n/a 1287401 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287406 unspecified role unspecified role prey prey n/a 1287404 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287403 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role prey prey association association false false false Fig. 4, 5B Observed in wild type cells, PEX4-/- and PEX8-/- pex6-pex1-1 1287395 n/a 1287403 unspecified role unspecified role prey prey n/a 1287404 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287399 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287406 unspecified role unspecified role prey prey association association false false false Figs. 5A Observed in wild-type cells and PEX4-/- pex6-pex1-1 1287395 n/a 1287401 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287403 unspecified role unspecified role prey prey association association false false false Figs. 5A Observed in PEX8-/-, PEX10-/- and PEX12-/- cells - levels of PEX5, PEX13 and PEX14 are very low. pex6-pex1-1 1287395 n/a 1287402 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287400 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey association association false false false Figs. 5A Observed in PEX14-/- cells - levels of PEX5 and PEX13 are very low. pex6-pex1-1 1287395 n/a 1287399 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role prey prey n/a 1287401 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287403 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey association association false false false Figs. 5A Observed in PEX8-/-, PEX10-/- and PEX12-/- cells. Levels of PEX5, PEX13 and PEX14 are very low. pex15-pex1-2 1287395 n/a 1287398 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287406 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287400 unspecified role unspecified role prey prey association association false false false Fig. 5B Interaction observed in PEX13-/- cells. pex15-pex1-2 1287395 n/a 1287406 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287399 unspecified role unspecified role prey prey n/a 1287398 unspecified role unspecified role prey prey association association false false false Fig. 5B Interaction observed in PEX14-/- cells. pex15-pex1-2 1287395 n/a 1287398 unspecified role unspecified role prey prey n/a 1287403 unspecified role unspecified role prey prey n/a 1287400 unspecified role unspecified role prey prey n/a 1287399 unspecified role unspecified role prey prey n/a 1287402 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 5B Interaction observed in PEX10-/- and PEX12-/- cells. pex1-pex6-6 1287396 n/a 1287399 unspecified role unspecified role neutral component neutral component region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287398 unspecified role unspecified role neutral component neutral component physical association physical association false false false Fig. 1C pex1-pex15-2 1287396 n/a 1287398 unspecified role unspecified role neutral component neutral component n/a 1287399 unspecified role unspecified role neutral component neutral component region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1287402 unspecified role unspecified role neutral component neutral component physical association physical association false false false Fig. 3B pex14-pex17-1 1287396 n/a 1287401 unspecified role unspecified role neutral component neutral component n/a 1287400 unspecified role unspecified role neutral component neutral component n/a 1287404 unspecified role unspecified role neutral component neutral component physical association physical association false false false Fig. 3B pex6-pex15 1287397 n/a 1287402 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1287398 unspecified role unspecified role bait bait physical association physical association false false false pex1-pex15-1 1287397 n/a 1287399 unspecified role unspecified role bait bait n/a 1287402 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1287398 unspecified role unspecified role ancillary ancillary physical association physical association false false false Fig. 2