UniProt UniProt http://www.uniprot.org minami-1994-1 The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. mouse-lymphoblast Mus musculus lymphoblast Transformed lymphocytes; Blast cell; Lymphoblastoid bn-page blue native page bn-page edman degradation edman degradation Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp Mol. Cell. Biol. (0270-7306) 1994 Only protein-protein interactions imex curation minami-1994-2 The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. in vitro In vitro bn-page blue native page bn-page autoradiography autoradiography Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp Mol. Cell. Biol. (0270-7306) 1994 Only protein-protein interactions imex curation minami-1994-3 The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. in vitro In vitro crosslink cross-linking study crosslink autoradiography autoradiography Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. Cross-linking agent 0.002% glutaraldehyde yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp Mol. Cell. Biol. (0270-7306) 1994 Only protein-protein interactions imex curation hs90a_mouse Heat shock protein HSP 90-alpha Hsp90aa1 Hsp86 Hsp86-1 Hspca Heat shock 86 kDa Tumor-specific transplantation 86 kDa antigen protein protein mouse Mus musculus Mouse MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMPPLEGDDDTSRMEEVD hs90a_human Heat shock protein HSP 90-alpha HSP90AA1 HSP90A HSPC1 Heat shock 86 kDa Renal carcinoma antigen NY-REN-38 HSPCA Lipopolysaccharide-associated protein 2 protein protein human Homo sapiens Human MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD hsp90aa1-hsp90aa1-3 1136418 n/a 1136421 unspecified role unspecified role neutral component neutral component Stoichiometry: 2.0 physical association physical association false false false fig1 and table 1 hsp90aa1-4 1136419 n/a 1136422 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro Stoichiometry: 2.0 physical association physical association false false false Fig. 2 hsp90aa1-4 1136420 n/a 1136422 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 2.0 physical association physical association false false false Fig. 2