<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1231232">
                <names>
                    <shortLabel>validandi-2011-1</shortLabel>
                    <fullName>Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22085609" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8283285" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="d-11-01644" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542587" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1016/j.febslet.2011.10.049" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16716" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-8283283" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>molecular sieving</shortLabel>
                        <fullName>molecular sieving</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Gel Filtration</alias>
                        <alias typeAc="MI:0303" type="go synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Gel Filtration</alias>
                        <alias typeAc="MI:1041" type="synonym">Sizing column</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0071" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1175" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Validandi V., Reddy VS., Srinivas PN., Mueller NH., Bhagyalaxmi SG., Padma T., Petrash JM., Reddy GB.</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2011</attribute>
                    <attribute name="imex-exported"/>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1231233">
                <names>
                    <shortLabel>cryaa_human</shortLabel>
                    <fullName>Alpha-crystallin A chain</fullName>
                    <alias typeAc="MI:0301" type="gene name">CRYAA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CRYA1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HSPB4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Heat shock protein beta-4</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P02489" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005198" secondary="structural molecule activity" version="SP_220"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000160202" version="SP_220" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008978" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051082" secondary="unfolded protein binding" version="SP_220"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001436" version="SP_220"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001300979.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007601" secondary="visual perception" version="SP_220"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-41265N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002068" version="SP_220"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-25838900" refType="intact-secondary"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003090" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050896" secondary="response to stimulus" version="SP_220"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P02489" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_220"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000291554" version="SP_220" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000291554" version="SP_220" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6T1R" version="SP_220"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A0A140G945" version="SP_220" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032387" secondary="negative regulation of intracellular transport" version="SP_220"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53X53" version="SP_147" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_220"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000385.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005212" secondary="structural constituent of eye lens" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" secondary="protein stabilization" version="SP_220"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E9PHE4" version="SP_220" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_220"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6875961" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_220"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012274" version="SP_220"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS</sequence>
            </interactor>
            <interactor id="1231234">
                <names>
                    <shortLabel>cryab_human</shortLabel>
                    <fullName>Alpha-crystallin B chain</fullName>
                    <alias typeAc="MI:0301" type="gene name">CRYAB</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CRYA2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Renal carcinoma antigen NY-REN-27</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Alpha(B)-crystallin</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rosenthal fiber component</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Heat shock protein beta-5</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HSPB5</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P02511" version="SP_98" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032432" secondary="actin filament bundle" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000533475" version="SP_239" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032355" secondary="response to estradiol" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014069" secondary="postsynaptic density" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043204" secondary="perikaryon" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SGS" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3L1G" version="SP_239"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC40" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043197" secondary="dendritic spine" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4M5T" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007517" secondary="muscle organ development" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097512" secondary="cardiac myofibril" version="SP_239"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-35017N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000433560" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000531198" version="SP_239" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005198" secondary="structural molecule activity" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" secondary="protein stabilization" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SGN" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031430" secondary="M band" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032387" secondary="negative regulation of intracellular transport" version="SP_239"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC39" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_239"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B0YIX0" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006457" secondary="protein folding" version="SP_239"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC38" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000435931" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_239"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43416" version="SP_98" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000498735" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005212" secondary="structural constituent of eye lens" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000434247" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000109846" version="SP_239" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051403" secondary="stress-activated MAPK cascade" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SGO" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000437149" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000227251" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008978" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000650687" version="SP_239" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071480" secondary="cellular response to gamma radiation" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Y22" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000436051" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4M5S" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Y1Z" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042542" secondary="response to hydrogen peroxide" version="SP_239"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003090" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007021" secondary="tubulin complex assembly" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_239"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3371571" version="SP_239"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037882" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905907" secondary="negative regulation of amyloid fibril formation" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043154" secondary="negative regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060561" secondary="apoptotic process involved in morphogenesis" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" secondary="amyloid-beta binding" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BP9" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2YGD" version="SP_239"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC41" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011540910.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010941" secondary="regulation of cell death" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030308" secondary="negative regulation of cell growth" version="SP_239"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-739060" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008017" secondary="microtubule binding" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000227251" version="SP_239" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WJ7" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2KLR" version="SP_239"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001276736.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015630" secondary="microtubule cytoskeleton" version="SP_239"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002068" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SGM" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3J07" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002088" secondary="lens development in camera-type eye" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Y1Y" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000527899" version="SP_239" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000533879" version="SP_239" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SGP" version="SP_239"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001876.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC37" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P02511" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010259" secondary="multicellular organism aging" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VVV" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000483554" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031333" secondary="negative regulation of protein-containing complex assembly" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000616970" version="SP_239" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097060" secondary="synaptic membrane" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000378" secondary="negative regulation of reactive oxygen species metabolic process" version="SP_239"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SGR" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000526180" version="SP_239" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000651164" version="SP_239" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N0K" version="SP_239"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000436089" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000499082" version="SP_239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000527950" version="SP_239" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_239"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001276737.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031109" secondary="microtubule polymerization or depolymerization" version="SP_239"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051082" secondary="unfolded protein binding" version="SP_239"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001436" version="SP_239"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK</sequence>
                <attributeList>
                    <attribute name="crc64">AE08BED46B7849CB</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-16716-1" id="1231235">
                <names>
                    <shortLabel>cryaa-cryaa-5</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8283288" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16716-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542598" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1231232</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1231236">
                        <names>
                            <shortLabel>cryaa_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">alphaA crystallin</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8283291" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542608" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1231233</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1231237">
                        <names>
                            <shortLabel>cryaa_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">alphaA crystallin</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8283290" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542605" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1231233</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f2a</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-16716-2" id="1231238">
                <names>
                    <shortLabel>cryaa-cryab-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8286941" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16716-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542611" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1231232</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1231239">
                        <names>
                            <shortLabel>cryab_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">alphaB crystallin</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8286945" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542621" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1231234</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1231240">
                        <names>
                            <shortLabel>cryaa_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">alphaA crystallin</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8286943" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7542618" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1231233</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f2b</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
