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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
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            <attributeList>
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                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1234712">
                <names>
                    <shortLabel>zhou-2012b-1</shortLabel>
                    <fullName>Cu(I)- and proton-binding properties of the first N-terminal soluble domain of Bacillus subtilis CopA.</fullName>
                </names>
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                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>molecular sieving</shortLabel>
                        <fullName>molecular sieving</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Gel Filtration</alias>
                        <alias typeAc="MI:0303" type="go synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Gel Filtration</alias>
                        <alias typeAc="MI:1041" type="synonym">Sizing column</alias>
                    </names>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Zhou L., Singleton C., Hecht O., Moore GR., Le Brun NE.</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="imex-exported"/>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="1234713">
                <names>
                    <shortLabel>zhou-2012b-2</shortLabel>
                    <fullName>Cu(I)- and proton-binding properties of the first N-terminal soluble domain of Bacillus subtilis CopA.</fullName>
                </names>
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                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
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                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>solution sedimentati</shortLabel>
                        <fullName>cosedimentation in solution</fullName>
                        <alias typeAc="MI:1041" type="synonym">solution sedimentati</alias>
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                    <names>
                        <shortLabel>predetermined</shortLabel>
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                <attributeList>
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                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="imex-exported"/>
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                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1234714">
                <names>
                    <shortLabel>copa_bacsu</shortLabel>
                    <fullName>Copper-exporting P-type ATPase</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Copper-exporting P-type ATPase A</alias>
                    <alias typeAc="MI:0301" type="gene name">copA</alias>
                    <alias typeAc="MI:0305" type="locus name">BSU33500</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">yvgX</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cu(+)-exporting ATPase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O32220" version="SP_69" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008250"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR044492"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023298"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OPZ"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023299"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_185"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RML"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_003242925.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_391230.2"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2VOY"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OQ6"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043682" secondary="P-type divalent copper transporter activity" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018303"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1P6T"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023214"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_185"/>
                    <secondaryRef db="ensemblbacteria" id="CAB15355" version="SP_185" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JWW"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OQ3"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005507" secondary="copper ion binding" version="SP_185"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017969"/>
                    <secondaryRef db="ensemblbacteria" id="BSU_33500" version="SP_185" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140581" secondary="P-type monovalent copper transporter activity" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001757"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1KQK"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006121"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036163"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
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                </interactorType>
                <organism ncbiTaxId="224308">
                    <names>
                        <shortLabel>bacsu</shortLabel>
                        <fullName>Bacillus subtilis</fullName>
                    </names>
                </organism>
                <sequence>MSEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQEKIEKLGYHVVTEKAEFDIEGMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTARLIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAYAYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEVLVNDIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQGSKAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGILFKGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPKLTRFEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARLKELGLDVIMMTGDNRRTAEAIAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTDIAMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVLNALRLQKVK</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-16734-2" id="1234715">
                <names>
                    <shortLabel>copa-copa</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288724" refType="identity" refTypeAc="MI:0356"/>
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                <experimentList>
                    <experimentRef>1234712</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1234716">
                        <names>
                            <shortLabel>copper-exporting p-t</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CopA</alias>
                        </names>
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                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288733" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7535028" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234714</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
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                                <xref>
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                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
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                        <experimentalRoleList>
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                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
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                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
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                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1234717">
                        <names>
                            <shortLabel>copper-exporting p-t</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CopA</alias>
                        </names>
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                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288726" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7535025" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234714</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
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                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
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                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f4</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-16734-1" id="1234718">
                <names>
                    <shortLabel>copa-1</shortLabel>
                </names>
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                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288784" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16734-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7535040" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1234713</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1234719">
                        <names>
                            <shortLabel>copper-exporting p-t</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CopA</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288786" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7535046" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234714</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 2.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f5</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
