MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint handler-2011-1 A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. drome-ocs cells Drosophila melanogaster ocs cells ocs cells anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Handler D., Olivieri D., Novatchkova M., Gruber FS., Meixner K., Mechtler K., Stark A., Sachidanandam R., Brennecke J. EMBO J. (0261-4189) 2011 Only protein-protein interactions imex curation handler-2011-2 A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. drome-ovary Drosophila melanogaster ovary ovary Ovary anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Handler D., Olivieri D., Novatchkova M., Gruber FS., Meixner K., Mechtler K., Stark A., Sachidanandam R., Brennecke J. EMBO J. (0261-4189) 2011 Only protein-protein interactions imex curation vret_drome Protein vreteno vret CG4771 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MESESSQDDWSAFDPMSREYYDQVGNRYTNESGQKLIMEAPLPPKDEKEQRATRQAKYPYLVVPKSSPYVTEKMLINFFGRALIKEMEFRRLSRVYFVYFENIASLETAQQRVQRYPNLIKCITGRPQKEREITSDPVTSTEPMPTPGPAISATERTPVNHNREVPISTGGQNHPEFFRPPLVTKDDYKRGSLLATNDPIQRYLNVKYEFALERHDIYKLKDETRIPQVVLHFRSGRTIPLSTVAVTEEDKTKSLLEDGVSKCVVCQNWTDTFCKLCKMPFCNASCFADVAEQHKQACGKGEILNLDEKVGRKYPKPGLPPSGSKVRITAFEQTNVVYVRSADIQIDIAYYTVLTEVMMLGKDASKLQSTPVCGQIVLYKFEGHMSRAMVLNVDNIKEIYVVFIDFGSVEVTQLERLYECSSYLAGLTCYPVAVKLRGVPRRFVGPNIREVMYELDQSLVFNIKYSSREYDTSKGMQVVVMTEIDINRSLNRLFKTILTPVEPSVSDLGYKEDCLPYIPLHCGKNINVVVMDNTFIQCGFIYCTSIDLAYEVTKMQRDIQEYGEKIAKCATYAPPINELCIAKYEGKWRRGLSVELVGDGYPSILFIDYGNIVPTHVTDIRPYPPQFIFPIMTTQLDLIGVPEKPTDEQIKWLDKNYPIGSVITCSEITFDEETNSYSTRIEKLQEFLSLD piwi_drome Protein piwi piwi CG6122 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MADDQGRGRRRPLNEDDSSTSRGSGDGPRVKVFRGSSSGDPRADPRIEASRERRALEEAPRREGGPTERKPWGDQYDYLNTRPAELVSKKGTDGVPVMLQTNFFRLKTKPEWRIVHYHVEFEPSIENPRVRMGVLSNHANLLGSGYLFDGLQLFTTRKFEQEITVLSGKSKLDIEYKISIKFVGFISCAEPRFLQVLNLILRRSMKGLNLELVGRNLFDPRAKIEIREFKMELWPGYETSIRQHEKDILLGTEITHKVMRTETIYDIMRRCSHNPARHQDEVRVNVLDLIVLTDYNNRTYRINDVDFGQTPKSTFSCKGRDISFVEYYLTKYNIRIRDHNQPLLISKNRDKALKTNASELVVLIPELCRVTGLNAEMRSNFQLMRAMSSYTRMNPKQRTDRLRAFNHRLQNTPESVKVLRDWNMELDKNVTEVQGRIIGQQNIVFHNGKVPAGENADWQRHFRDQRMLTTPSDGLDRWAVIAPQRNSHELRTLLDSLYRAASGMGLRIRSPQEFIIYDDRTGTYVRAMDDCVRSDPKLILCLVPNDNAERYSSIKKRGYVDRAVPTQVVTLKTTKNRSLMSIATKIAIQLNCKLGYTPWMIELPLSGLMTIGFDIAKSTRDRKRAYGALIASMDLQQNSTYFSTVTECSAFDVLANTLWPMIAKALRQYQHEHRKLPSRIVFYRDGVSSGSLKQLFEFEVKDIIEKLKTEYARVQLSPPQLAYIVVTRSMNTRFFLNGQNPPPGTIVDDVITLPERYDFYLVSQQVRQGTVSPTSYNVLYSSMGLSPEKMQKLTYKMCHLYYNWSGTTRVPAVCQYAKKLATLVGTNLHSIPQNALEKKFYYL armi_drome Probable RNA helicase armi armi Protein armitage CG11513 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MFTYVSKFFTNPDRNREDILESLDRENSFLDQKLMEEKMDQQLKANPNEINGVLSNKIAELTHGLSEMDVSKESSCTARKGVITSLDGDRGVIDKDVLFETKVAEDIILDLHVGCVVEYLTFTTGEAMRVVKVKSILEHSWEDTSQKEIEKAVDNLKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQLTVELDNIEMNFIPTNGDRVRLECNIQLDDGFVDKQGEILEVTKLFPTRIQEGEKCIVERVYVHMVVLGPETYILKTDLPTGTDLHLGDIVLADLIECQYSKFTRRAIKITPLEKNFGATKLTQQSSMGSSGSGKAVTVTGVNRFITAELWQKESVSLKLTNNLNRTLRLESITVCNDSESQLSVVSPLESKEISSGSEITVTFEIHTQFLGEAIEKYVLNFDLLKVRRVFTVIVCKTKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLGCFEVPKELRQICLTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQIENLAERRPSLVIGDTLRVINPWSDPDSQTTKSYEGIIHKVLFDRILLKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILFCVKNNAYFGCDLPQMVINQKDEVPVCLETFVPSLNTTDDLN q9w4w2_drome fs(1)Yb Dmel\CG2706 EG:95B7.8 YB Yb fs(1)M104 fs(1)Y[b] nov yb Dmel_CG2706 CG2706 Fs(1)Yb protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MEPIGDLQVPSFKVVSGGTTFTYASPKSGAASLDFLAHTLRKREANTEKTILICQQNFEAERLKFELAERDVNTILLPPHGAMVGQVLLLWSKGYINQALILCDGMLEHLGVVEANLVIHTTLPELNKFEERLKWLSISARNAEMLVITPCDEENEKEGKGETEPEIVQQRMPLKVDALNSMQLYEIKENTPPTSSEDYKAEADVLLSAATPATIPNDNKEQEINLSVEDATVKLLASFELGSTDSAAVDESSPAAAKFNAPVYSPFVTENPTKSLDAEFQELVKSFKVQNVFKNMNLPPPPSVSIEEPVSSASASDYRHQIDTTSLDSIRTVKDSPASLAVVPFSAGGITYNNYGVLGWSRHAVVPCYGLTEAPDISTIIRRAMQQMGVARSRARAVQRFAWPHVSLGKSVLVVGNLQIGKTWSYLPTVCQRSHEDLQRRPDVGRGPTCIFVCPNQGQGKQIERWMSTLLCLLGSASGFEDVVTHWDKTQLVDIVRRLKKPVGILLTSVDLLLQLLNHNPVGSIFDAQAVKCIALDNLNDMVRVLPNDTMKLLQRLPEMFQLTQNKCQLLVSGRIWHTDLMVQHILPLMPDVLVLFDDALEASVYGGVQLDVRVVADEPEKIEHLKALIAERRNFANEPAVMVCSNSTEVLLLRRSLQAIGVNAHICVSEACYSNVAEWLRQSPSGLLLVTDDVVPRLKCGKIPLLIHYSFASMWARFKNRFSLFYANLKSPTTRPVGQSVVFAKPTDLENIWKLCDFYMKHKLPRPGHLLGILSQRRLEEQPTSRSLCHQMAAFGDCLRHKCMYRHVMWRDEVLPPDHYPKNGLIRFLVLVCYSPAALAVRLSDQFPTAIRFLNFPMSDLGERVQRHYELEANRHMHPNPVPGEMAVVKNINRYERVHIVSVESNVMVLVQLLDTSTECFSYKTSQLYSCDKIFKDSPREAMDLRILGLQPESLDRIWPDDARNLVRKDFFRRTHNKRNRQFHAVVQSAIHRTIFVRNIYDDEGNDLLSFVINRFRSHQDECCQLKLDAMVMSSKDCPYM soyb_drome Putative ATP-dependent RNA helicase SoYb Sister of Yb CG31755 SoYb protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MEHQLDPDQEESILITHFVNPHQFSYVRCIDVENSAMLVRQIEQDLKDYCSSERTKQVYVEDERVIVRYQRWSPPKLVRGVVRRRQNEEYLVWILDYGFNLCCSVWDLWPLPDHLSRSLCDFKEGGVALIAPHSGSVWSRSAIESLDKQLEDANQLTFQVVHRGKSNRNFGLLKFRSSCQTEDAANFLIKQDQGRCKETLTMAIPYEDISFEKAEINDMAIDTRPRLRRILELVVLLSENAKESTPTPSAIQQKKLDALLQSHETYLIPNSVKLLSKVQSISESSMQTALANRSKQISKELPHKANQSEDNRKKEVKYLESENLSECLSKVKLSSYQQKNTDSSTLSGPRNLASSSTNSNSNVRKSMTLFKSSGAHLTTSLSVPLTENCTNQSNNRTVVFSMDKMEQIFNDMLGKNPSERSVQKNRSQMPNSNVSTTKRCVEKMHVCRSENMGDRKPSVCLKHLVLAHSPEPVNPVTSYKELPLGNTILNAMDDLNFQTPLPTQIYAWPHLVNRGSLVLVNPSGTGRSWSYLPVICSSVLSSFENVTSNLDTRIAPGPLAILIVDSVENAKKLASHCEFLMKDFNTQNLKVVNTHAHSMMDVYMMLLNSCGVLVTTLAHLNNILSNELPLVNPTRLEFIIFDDYDRKRLDNAELLKEVFQKVNSIGGLSKQLVLVAQQWHSERFQKLLNRTTKPLILFGDFLEAALYGGLKFNVTLRSSALKARQLLDILAEQDGSKKRTLIYCKNQMELEELSAILIEAGLQCVDISKAQNQSPNRLMLVDDSQVRKQLPVRNIQLLIHFSLPESWLRFSRRFHTMADNIRNLFTKPIGRGQDLITYILMDENNAKEWPRIMKFLQDHGLTTQSMPDSEQQLDNTLPYCPYKLSNGNCNRNQCNKRHHFLKTDLPKIGNPLLQPGTLIRCKFLKAYDPAHMAVMPMKYKSKDSTIWIDVPYPSYPSTLVFKMSFGVPRKVHNPCKINDVCFVQHKELLSRVRIVDNPARPQVTVQLMDYGTELLQVKASQLLECPEQFRDLQQLAMDIRLSGLAGSGQGGMWSTDSIQWVQDRFADINEEIMQITVDFGVLDVAYVKEIALIEECPTMLTSVYKTFLRKELLRQGFAKIDSTSILELRAIHEQWKQEMEELRANKENIVCSSTDLDNRDSKITSLQNKQATCSSGKEEDLNPVETPLIIASPNSNETLEERKHVSDKVQNKIDELNDFNKSVEIEHVQDASPLDSSTALINTLIHELNTKSPTKKKNTQEFIKNIVHEDETQSIHHEISSSTNSLKQDKTIVVGPQDPPKELFLQYLNCATKSRESVYPMVKWHQTLTHIELVVEQQMLEYKLGLDGNTLEYKVNETTPPQRFILNLLGEVRIDSVKQHGYYLHIKLTKVGLLFHWPTLLNSLYVQKHAHWLIYDSERSHGPPPSFGLVLWEGYLTHKKTKSYSDSESSEFSSTPEDFIEPGVEYCEMDSNLYED hsp27_drome Heat shock protein 27 Hsp27 CG4466 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSIIPLLHLARELDHDYRTDWGHLLEDDFGFGVHAHDLFHPRRLLLPNTLGLGRRRYSPYERSHGHHNQMSRRASGGPNALLPAVGKDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNEVVSTVSSDGVLTLKAPPPPSKEQAKSERIVQIQQTGPAHLSVKAPAPEAGDGKAENGSGEKMETSK boyb_drome Putative ATP-dependent RNA helicase BoYb Brother of Yb CG11133 BoYb protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MIKISDEKTWQSSRDSVYEVGDSYSGQNANRPLVATNCSEYAVAHANCQLRPVRRFAEVSLLPDILETMRNLGLNRLLRLQSYTWPHLAGGSGHGAMIVGSPASGRTFAYIPPVCHAVSRALMDFTGQCEDVEHDISQPDRYGPIALILVPDLRRVHQVSAMCLALLRKAHKNDSVTLALNVSSTKSSQFFLKLLNGVGCLVATPAQLVWFWQEAPGLMRFPCLQFLVYDDVDLMSREQLQDVQQVLQEILPLSHSPQVVMVSKSYCHTLMSKLRAVNDKPALVFGDILEAALYGGTRIRISIMRSEAKANAVVQMLQQCSPEEFRTVIFCSDDGDMQCLVAALEVQHYSCLPYYQTADLEVRQQVHSWQARSNGVILLCTDNCPELDIRDAHTIIHHSMSHSWSKFKLRHLKISDNLCNMVKPTASIVKKPLYSLVLLDDNNHRQLPRLVDFLQLHQKVDHRLVEVAKRIRQELGKARNDQHQLCDQILVLGKCYDPVCESRHRLSHIDRRPDYLPASGDVKVQLVKVYSPTHFCVRLLEHLPPKGTWRMMEYSAVQEFRMQLTQIKEPRRYWPPVAGAICMYHTTFTKERVRVLKVAAIKNTNIVQSDLTVKLQALDVDTRIFSTNCGKLFECPEALQQEAPLACDLRLPGWVPYFGERSWTEENIRNVNLILTQLPKDHFLQAKILFVAAGTLFVQDLVAIMYADQFKAHVRHLSLARRLVEATLVKRSENAAEMIREFFAEVIIEDDIDENVQDSKEKANSKPHEKMKGKMTDQPAKLQSQPPLSGRCLRLANMAHESVKENQLHQELQERRYETPEIPHQSNESDIPQSNEDRFSQLYECIMNCASLQLEDESKPAKHPDHVLSESVEFHKIMTNEDATPDHTQEKTALLLLPNNVARPSVTYYQTMTTLEFQVFLPEDDHDYKALLLGAQLFFRAISKSSDLILQFIMTLRFPYSSMSHNIRGRTVYISVKKLLALIDPLAFREYRFLKPNHDLFDKVDKQLQETQNRLVRFLEDMNYVKRNFEGQEKRETSEDEEVNVEGIERPDCHKIWDL q9vxr5_drome Dmel\CG9281 BEST:LD38280 CG9281 Dmel_CG9281 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSSAAKKREAQKKKDARNKKIQQIPSTKKANGVPERELTEEEKLCAKLEEEARISAEARSCTGSLAVHPRSRDVKIANFSITFFGSELLQDTMLELNCGRRYGLIGLNGCGKSSLLAVLGGREVPVPPHIDIFHLTREIPASSKSALQCVMEVDEERIKLEKLAEELAMSEEDDAQEQLIDIYERLDDMSADLAEVKAARILHGLGFDKAMQQKQAKDFSGGWRMRIALARALFVKPHLLLLDEPTNHLDLDACVWLEEELKTYKRILVLISHSQDFLNGVCTNIIHLTGKRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQISHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDKVLNFYFPSCGKVPPPVIMVQNVNFRYNDETPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPTSGMIRKNSHLRIARYHQHLHELLDLDASPLEYMMRAFPDVKEKEEMRKIIGRYGLTGRQQVCPIRQLSDGQRCRVVFAWLAWQVPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRLINQVAEEIWVCEKETVTKWKGGILDYKDHLKNKITSENEKKAKAGK armi-fs_1_yb 1233520 q9vcu7_drome Vreteno 1233522 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level piwi_drome piwi 1233523 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level armi_drome Armitage 1233524 western blot western blot Immuno blot Immuno blot unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level q9w4w2_drome Yb 1233525 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level association association false false false f7e mint vret-armi 1233520 armi_drome Armitage 1233524 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level q9vcu7_drome Vreteno 1233522 western blot western blot Immuno blot Immuno blot unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level q9w4w2_drome Yb 1233525 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level piwi_drome piwi 1233523 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level association association false false false f7e mint vret-boyb 1233521 cg31755 CG31755 1233526 ms participant Identification by mass spectrometry ms participant unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level q9vcu7_drome CG4771 1233522 ms participant Identification by mass spectrometry ms participant unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level hsp27_drome Hsp27 1233527 ms participant Identification by mass spectrometry ms participant unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level q9vcu7_drome Vreteno 1233522 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell gfp tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false q9vnp5_drome CG11133 1233528 ms participant Identification by mass spectrometry ms participant unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level q9vxr5_drome CG9281 1233529 ms participant Identification by mass spectrometry ms participant unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level association association false false false mint st3