IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ basu-2011-5 The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Basu U., Meng FL., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman CR., Wesemann DR., Januszyk K., Gregory RI., Deng H., Lima CD., Alt FW. Origin of constructs confirmed by the author. alt@enders.tch.harvard.edu, ub2121@columbia.edu Cell (0092-8674) 2011 Only protein-protein interactions imex curation basu-2011-1 The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. human-ramos Human Caucasian Burkitt's lymphoma ramos Human Caucasian Burkitt's lymphoma anti bait coip anti bait coimmunoprecipitation anti bait coip sequence tag sequence tag identification sequence tag Basu U., Meng FL., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman CR., Wesemann DR., Januszyk K., Gregory RI., Deng H., Lima CD., Alt FW. DNA-protein complexes were purified via chromatographic steps that would enrich for DNA binding (CM-sepharose, DEAE cellulose) and macromolecular complex formation (gel-filtration chromatography), followed by heparin sepharose chromatography and anti-AID antibody-mediated affinity purification to enrich complexes containing AID alt@enders.tch.harvard.edu, ub2121@columbia.edu Cell (0092-8674) 2011 Only protein-protein interactions imex curation basu-2011-2 The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. mouse-b-cell Mus musculus B-cell b-cell B-cell [B lymphocyte; B-lymphocyte; B cell; B-cells] anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Basu U., Meng FL., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman CR., Wesemann DR., Januszyk K., Gregory RI., Deng H., Lima CD., Alt FW. Cells treated with anti-CD40 plus IL-4 alt@enders.tch.harvard.edu, ub2121@columbia.edu Cell (0092-8674) 2011 Only protein-protein interactions imex curation basu-2011-3 The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. mouse-b-cell lymphoma Mus musculus B-cell lymphoma b-cell lymphoma B-cell lymphoma anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Basu U., Meng FL., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman CR., Wesemann DR., Januszyk K., Gregory RI., Deng H., Lima CD., Alt FW. alt@enders.tch.harvard.edu, ub2121@columbia.edu Cell (0092-8674) 2011 Only protein-protein interactions imex curation basu-2011-4 The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. human-ramos Human Caucasian Burkitt's lymphoma ramos Human Caucasian Burkitt's lymphoma anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Basu U., Meng FL., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman CR., Wesemann DR., Januszyk K., Gregory RI., Deng H., Lima CD., Alt FW. DNA-protein complexes were purified via chromatographic steps that would enrich for DNA binding (CM-sepharose, DEAE cellulose) and macromolecular complex formation (gel-filtration chromatography), followed by heparin sepharose chromatography and anti-AID antibody-mediated affinity purification to enrich complexes containing AID alt@enders.tch.harvard.edu, ub2121@columbia.edu Cell (0092-8674) 2011 Only protein-protein interactions imex curation exos3_human Exosome complex component RRP40 EXOSC3 RRP40 CGI-102 Ribosomal RNA-processing protein 40 Exosome component 3 p10 protein protein human Homo sapiens Human MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES exosx_human Exosome component 10 PMSCL2 EXOSC10 PMSCL Polymyositis/scleroderma autoantigen 2 Autoantigen PM/Scl 2 Polymyositis/scleroderma autoantigen 100 kDa P100 polymyositis-scleroderma overlap syndrome-associated autoantigen RRP6 protein protein human Homo sapiens Human MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVILERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNIIRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR aicda_mouse Single-stranded DNA cytosine deaminase Aicda Aid Cytidine aminohydrolase Activation-induced cytidine deaminase protein protein mouse Mus musculus Mouse MDSLLMKQKKFLYHFKNVRWAKGRHETYLCYVVKRRDSATSCSLDFGHLRNKSGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAEFLRWNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIGIMTFKDYFYCWNTFVENRERTFKAWEGLHENSVRLTRQLRRILLPLYEVDDLRDAFRMLGF exos1_human Exosome complex component CSL4 CSL4 EXOSC1 CGI-108 Exosome component 1 protein protein human Homo sapiens Human MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT exos2_human Exosome complex component RRP4 EXOSC2 RRP4 Ribosomal RNA-processing protein 4 Exosome component 2 protein protein human Homo sapiens Human MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG exos5_human Exosome complex component RRP46 EXOSC5 CML28 RRP46 Ribosomal RNA-processing protein 46 Exosome component 5 p12B Chronic myelogenous leukemia tumor antigen 28 protein protein human Homo sapiens Human MEEETHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVLQVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAVLTFALDSVERKLLMSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKS exos4_human Exosome complex component RRP41 EXOSC4 RRP41 SKI6 Ribosomal RNA-processing protein 41 Exosome component 4 p12A protein protein human Homo sapiens Human MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQIDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAAGGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREASILLGD exos6_human Exosome complex component MTR3 EXOSC6 MTR3 Exosome component 6 mRNA transport regulator 3 homolog p11 protein protein human Homo sapiens Human MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPVLNQVAGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP exos7_human Exosome complex component RRP42 KIAA0116 RRP42 EXOSC7 Ribosomal RNA-processing protein 42 Exosome component 7 p8 protein protein human Homo sapiens Human MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG exos8_human Exosome complex component RRP43 OIP2 RRP43 EXOSC8 Ribosomal RNA-processing protein 43 Exosome component 8 p9 Opa-interacting protein 2 protein protein human Homo sapiens Human MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK rrp44_human Exosome complex exonuclease RRP44 DIS3 Ribosomal RNA-processing protein 44 Protein DIS3 homolog KIAA1008 RRP44 protein protein human Homo sapiens Human MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK aicda_human Single-stranded DNA cytosine deaminase AICDA AID Cytidine aminohydrolase Activation-induced cytidine deaminase protein protein human Homo sapiens Human MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL exos5_mouse Exosome complex component RRP46 Ribosomal RNA-processing protein 46 Exosome component 5 Exosc5 D7Wsu180e Rrp46 protein protein mouse Mus musculus Mouse MEGAKRADANLLTDTGTESSPRSPVCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLVRNTCEAVVLGALHPRTSITVVLQVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVTCALDSDGNLVLDPTTKQEKEARAILTFALDSAEQKLLMSTTKGLYSDAELQQCLAAAQAASQHIFRFYRESLQRRYSKS exos3_mouse Exosome complex component RRP40 Exosc3 Rrp40 Exosome component 3 Ribosomal RNA-processing protein 40 protein protein mouse Mus musculus Mouse MAEVLSAGPESVAGCRARAVHKVLNQVVLPGEELVLPDHEDVDGLGGAGEQPLRLNAGARPRLRVVCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARLAES exos6_mouse Exosome complex component MTR3 Exosc6 Mtr3 Exosome component 6 mRNA transport regulator 3 homolog protein protein mouse Mus musculus Mouse MPGDHRRIRGPEESQPPQLYAAEDDETPAARDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGSGPAGAGGEAPAALRGRLLCDFRRAPFSGRRRRAPQGGGGEDRELGLALQEALEPAVRLGRYPRAQLEVSALLLEDGGCALAAALTAAALALADAGVEMYDLVVGCGLSLTPGPSPTWLLDPTRLEEEHSAAGLTVALMPVLNQVAGLLGSGEGGQTESWTDAVRLGLEGCQRLYPVLQQCLVRAARRRGAAAPP exosc1-exosc9 1129633 n/a 1129638 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129641 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 2C exosc2-aicda 1129633 n/a 1129642 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role prey prey association association false false false Fig. 2C exosc5-aicda 1129633 n/a 1129639 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129643 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 2C exosc4-aicda 1129633 n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role prey prey n/a 1129644 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 2C exosc3-aicda-2 1129633 n/a 1129638 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role prey prey association association false false false Fig. 2C exosc6-aicda 1129633 n/a 1129645 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1129639 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey association association false false false Fig. 2C exosc7-aicda 1129633 n/a 1129639 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129646 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 2C exosc8-aicda 1129633 n/a 1129647 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1129640 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey association association false false false Fig. 2C exosc10-aicda 1129633 n/a 1129639 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 2C exosc9-aicda-1 1129633 n/a 1129639 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey association association false false false Fig. 2C dis3-exosc10 1129633 n/a 1129638 unspecified role unspecified role prey prey n/a 1129639 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role prey prey n/a 1129648 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false association association false false false Fig. 2C aicda-exosc1 1129634 n/a 1129649 unspecified role unspecified role bait bait n/a 1129641 unspecified role unspecified role prey prey n/a 1129646 unspecified role unspecified role prey prey n/a 1129647 unspecified role unspecified role prey prey n/a 1129645 unspecified role unspecified role prey prey n/a 1129638 unspecified role unspecified role prey prey n/a 1129642 unspecified role unspecified role prey prey n/a 1129643 unspecified role unspecified role prey prey n/a 1129644 unspecified role unspecified role prey prey association association false false false Fig 1A, 1B, Supp. Table 1 aicda-exos3 1129635 n/a 1129650 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role bait bait n/a 1129651 unspecified role unspecified role prey prey n/a 1129652 unspecified role unspecified role prey prey association association false false false Fig. 2A aicda-exos3-1 1129636 n/a 1129651 unspecified role unspecified role prey prey n/a 1129652 unspecified role unspecified role prey prey n/a 1129640 unspecified role unspecified role bait bait n/a 1129650 unspecified role unspecified role prey prey association association false false false Fig. 2B anti-CD40, IL-4, and TGF-beta aicda-exosc3 1129637 n/a 1129638 unspecified role unspecified role prey prey n/a 1129643 unspecified role unspecified role prey prey n/a 1129649 unspecified role unspecified role bait bait n/a 1129645 unspecified role unspecified role prey prey association association false false false Fig 1A, 1B, Supp. Table 1