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                    <fullName>Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.</fullName>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL</sequence>
            </interactor>
            <interactor id="1234739">
                <names>
                    <shortLabel>2aaa_human</shortLabel>
                    <fullName>Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform</fullName>
                    <alias typeAc="MI:0301" type="gene name">PPP2R1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PP2A subunit A isoform PR65-alpha</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PP2A subunit A isoform R1-alpha</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Medium tumor antigen-associated 61 kDa protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P30153" version="SP_83" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DW8" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975957" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358749" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019888" secondary="protein phosphatase regulator activity" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5W0W" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008380" secondary="RNA splicing" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2465910" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NPP" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2467813" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR021133" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380270" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_218"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29394N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6NTS" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96DH3" version="SP_83" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8854518" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042532" secondary="negative regulation of tyrosine phosphorylation of STAT protein" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69273" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-196299" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0065003" secondary="protein-containing complex assembly" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000188" secondary="inactivation of MAPK activity" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5467340" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-432142" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045595" secondary="regulation of cell differentiation" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000322088" version="SP_218" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2995383" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007059" secondary="chromosome segregation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" secondary="protein heterodimerization activity" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PKG" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68877" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13773" version="SP_83" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030155" secondary="regulation of cell adhesion" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198753" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380320" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0040008" secondary="regulation of growth" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5467348" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-113501" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006470" secondary="protein dephosphorylation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019932" secondary="second-messenger-mediated signaling" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K7V" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-163767" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5620912" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006672" secondary="ceramide metabolic process" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000324804" version="SP_218" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358751" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" secondary="regulation of transcription, DNA-templated" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7K36" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NYM" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-180024" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6ICQ3" version="SP_83" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358747" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5467337" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4641262" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-141444" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000105568" version="SP_218" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380259" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015630" secondary="microtubule cytoskeleton" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IE3" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2500257" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-195253" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031090" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IE4" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9634600" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5339716" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016328" secondary="lateral plasma membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000775" secondary="chromosome, centromeric region" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I5N" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NYL" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016024" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-163685" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5663220" version="SP_218"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-302388" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7CUN" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2565942" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1B3U" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202670" version="SP_218"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P30153" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380284" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I5L" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3C5W" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006275" secondary="regulation of DNA replication" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000159" secondary="protein phosphatase type 2A complex" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030425" secondary="dendrite" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990405" secondary="protein antigen binding" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358752" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-389513" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011989" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5675221" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LAC" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69231" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K7W" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030111" secondary="regulation of Wnt signaling pathway" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5673000" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648025" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6IUR" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030308" secondary="negative regulation of cell growth" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_055040.2"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000357" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804757" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010033" secondary="response to organic substance" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1295596" version="SP_218"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA</sequence>
            </interactor>
            <interactor id="1234740">
                <names>
                    <shortLabel>pp2ab_human</shortLabel>
                    <fullName>Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform</fullName>
                    <alias typeAc="MI:0301" type="gene name">PPP2CB</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P62714" version="SP_44" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-42325N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070262" secondary="peptidyl-serine dephosphorylation" version="SP_171"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P62714" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004722" secondary="protein serine/threonine phosphatase activity" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_171"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P11082" version="SP_44" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904528" secondary="positive regulation of microtubule binding" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" secondary="protein C-terminus binding" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-195253" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358747" version="SP_171"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DSV4" version="SP_77" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043161" secondary="proteasome-mediated ubiquitin-dependent protein catabolic process" version="SP_171"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1044367" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202670" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008637" secondary="apoptotic mitochondrial changes" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2467813" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_171"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000221138" version="SP_171" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000775" secondary="chromosome, centromeric region" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046677" secondary="response to antibiotic" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-163685" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042542" secondary="response to hydrogen peroxide" version="SP_171"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004843" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69273" version="SP_171"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001009552.1"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5467340" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-196299" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2465910" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9634600" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-180024" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-389513" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034976" secondary="response to endoplasmic reticulum stress" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5675221" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048156" secondary="tau protein binding" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69231" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-163767" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358751" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" secondary="regulation of gene expression" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68877" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046580" secondary="negative regulation of Ras protein signal transduction" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5673000" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106307" secondary="protein threonine phosphatase activity" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000922" secondary="spindle pole" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198753" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5467337" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-432142" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-113501" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358752" version="SP_171"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006186" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035970" secondary="peptidyl-threonine dephosphorylation" version="SP_171"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000104695" version="SP_171" refType="gene"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5339716" version="SP_171"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000221138" version="SP_171" refType="transcript"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6FHK5" version="SP_66" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029052" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2500257" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010288" secondary="response to lead ion" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648025" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000159" secondary="protein phosphatase type 2A complex" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1295596" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106306" secondary="protein serine phosphatase activity" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358749" version="SP_171"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006470" secondary="protein dephosphorylation" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804757" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-141444" version="SP_171"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4641262" version="SP_171"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL</sequence>
            </interactor>
            <interactor id="1234741">
                <names>
                    <shortLabel>foxo3_human</shortLabel>
                    <fullName>Forkhead box protein O3</fullName>
                    <alias typeAc="MI:0301" type="gene name">FOXO3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKHRL1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FOXO3A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Forkhead in rhabdomyosarcoma-like 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">AF6q21 protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O43524" version="SP_89" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000385824" version="SP_224" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1644164" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011533930.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006390" secondary="mitochondrial transcription" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1181150" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030456" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6MNL" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001547" secondary="antral ovarian follicle growth" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001221" secondary="transcription coregulator binding" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9615017" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001544" secondary="initiation of primordial ovarian follicle growth" version="SP_224"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BZ04" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097192" secondary="extrinsic apoptotic signaling pathway in absence of ligand" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034246" secondary="mitochondrial transcription factor activity" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000353" secondary="positive regulation of endothelial cell apoptotic process" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032067" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8952158" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9634638" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097150" secondary="neuronal stem cell population maintenance" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071548" secondary="response to dexamethasone" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_224"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DVZ6" version="SP_158" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LQI" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903428" secondary="positive regulation of reactive oxygen species biosynthetic process" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9617629" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005266925.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034599" secondary="cellular response to oxidative stress" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045665" secondary="negative regulation of neuron differentiation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" secondary="tumor necrosis factor-mediated signaling pathway" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030330" secondary="DNA damage response, signal transduction by p53 class mediator" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014737" secondary="positive regulation of muscle atrophy" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9617828" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001766" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9614657" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001556" secondary="oocyte maturation" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9614399" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000406360" version="SP_224" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042149" secondary="cellular response to glucose starvation" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2K86" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902895" secondary="positive regulation of pri-miRNA transcription by RNA polymerase II" version="SP_224"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29723N"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5674400" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001446.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000118689" version="SP_224" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000343882" version="SP_224" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" secondary="aging" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9607240" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" secondary="beta-catenin binding" version="SP_224"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5T2I7" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042594" secondary="response to starvation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010508" secondary="positive regulation of autophagy" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090090" secondary="negative regulation of canonical Wnt signaling pathway" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030336" secondary="negative regulation of cell migration" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901300" secondary="positive regulation of hydrogen peroxide-mediated programmed cell death" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990090" secondary="cellular response to nerve growth factor stimulus" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001542" secondary="ovulation from ovarian follicle" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032068" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000339527" version="SP_224" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005759" secondary="mitochondrial matrix" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" secondary="DNA-binding transcription factor activity" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000177" secondary="regulation of neural precursor cell proliferation" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011533931.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E1P5E6" version="SP_118" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198693" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785807" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005741" secondary="mitochondrial outer membrane" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5687128" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2UZK" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043525" secondary="positive regulation of neuron apoptotic process" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LQH" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071386" secondary="cellular response to corticosterone stimulus" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" secondary="sequence-specific double-stranded DNA binding" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031490" secondary="chromatin DNA binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990785" secondary="response to water-immersion restraint stress" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_963853.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048854" secondary="brain morphogenesis" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045648" secondary="positive regulation of erythrocyte differentiation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070542" secondary="response to fatty acid" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001227" secondary="DNA-binding transcription repressor activity, RNA polymerase II-specific" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006417" secondary="regulation of translation" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8862803" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_224"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O15171" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016866075.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071333" secondary="cellular response to glucose stimulus" version="SP_224"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG</sequence>
                <attributeList>
                    <attribute name="crc64">E5B4E830665A9982</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="1234742">
                <names>
                    <shortLabel>foxo3-ppp2ca</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288927" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771615" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1234736</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1234743">
                        <names>
                            <shortLabel>pp2aa_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288931" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771626" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234738</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1234744">
                        <names>
                            <shortLabel>2aaa_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288930" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771624" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234739</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1234745">
                        <names>
                            <shortLabel>pp2ab_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288932" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771622" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234740</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1234746">
                        <names>
                            <shortLabel>foxo3_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288929" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771620" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234741</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f2a f2b</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction id="1234747">
                <names>
                    <shortLabel>foxo3-ppp2r1a</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288942" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771654" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1234737</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1234748">
                        <names>
                            <shortLabel>2aaa_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288945" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771661" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234739</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1234749">
                        <names>
                            <shortLabel>foxo3_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8288944" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7771659" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1234741</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">f2e f2c f2d</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
