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<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2011-03-03Z">
            <names>
                <shortLabel>UniProt</shortLabel>
                <fullName>UniProt</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0486" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3989247" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1021583">
                <names>
                    <shortLabel>petersen-2003-1</shortLabel>
                    <fullName>S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="12676091" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-3647412" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16942" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="4896">
                        <names>
                            <shortLabel>schpm</shortLabel>
                            <fullName>Schizosaccharomyces pombe (fission yeast)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Petersen J., Hagan IM.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">jpetersen@picr.man.ac.uk, ihagan@picr.man.ac.uk</attribute>
                    <attribute name="journal" nameAc="MI:0885">Curr. Biol. (0960-9822)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2003</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1021584">
                <names>
                    <shortLabel>mad2_schpo</shortLabel>
                    <fullName>Mitotic spindle checkpoint component mad2</fullName>
                    <alias typeAc="MI:0301" type="gene name">mad2</alias>
                    <alias typeAc="MI:0306" type="orf name">SPBC20F10.06</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O14417" version="SP_54" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003511" version="SP_145"/>
                    <secondaryRef db="ensemblfungi" id="SPBC20F10.06.1:pep" version="SP_145" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036570" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034399" secondary="nuclear periphery" version="SP_145"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-38037N"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SPO-141405"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045841" secondary="negative regulation of mitotic metaphase/anaphase transition" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990498" secondary="mitotic spindle microtubule" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033316" secondary="meiotic spindle assembly checkpoint signaling" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007094" secondary="mitotic spindle assembly checkpoint signaling" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044732" secondary="mitotic spindle pole body" version="SP_145"/>
                    <secondaryRef db="ensemblfungi" id="SPBC20F10.06.1" version="SP_145" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4AEZ" version="SP_145"/>
                    <secondaryRef db="ensemblfungi" id="SPBC20F10.06" version="SP_145" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_145"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1269310" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027097" version="SP_145"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SPO-141430"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033597" secondary="mitotic checkpoint complex" version="SP_145"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_596370.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044779" secondary="meiotic spindle checkpoint signaling" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000776" secondary="kinetochore" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010997" secondary="anaphase-promoting complex binding" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905318" secondary="meiosis I spindle assembly checkpoint signaling" version="SP_145"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="284812">
                    <names>
                        <shortLabel>schpo</shortLabel>
                        <fullName>Schizosaccharomyces pombe (strain ATCC 38366 / 972)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                    </names>
                </organism>
                <sequence>MSSVPIRTNFSLKGSSKLVSEFFEYAVNSILFQRGIYPAEDFKVVRKYGLNMLVSVDEEVKTYIRKIVSQLHKWMFAKKIQKLILVITSKCSGEDLERWQFNVEMVDTADQFQNIGNKEDELRVQKEIQALIRQITATVTFLPQLEEQCTFNVLVYADKDSEVPTDWVDSDPRILRDAEQVQLRSFSTSMHKIDCQVAYRVNP</sequence>
                <attributeList>
                    <attribute name="crc64">DC9D1D213450C925</attribute>
                </attributeList>
            </interactor>
            <interactor id="1021585">
                <names>
                    <shortLabel>mad3_schpo</shortLabel>
                    <fullName>Mitotic spindle checkpoint component mad3</fullName>
                    <alias typeAc="MI:0301" type="gene name">mad3</alias>
                    <alias typeAc="MI:0306" type="orf name">SPCC1795.01c</alias>
                    <alias typeAc="MI:0306" type="orf name">SPCC895.02</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O59767" version="SP_41" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblfungi" id="SPCC1795.01c.1:pep" version="SP_139" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-39397N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010997" secondary="anaphase-promoting complex binding" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990948" secondary="ubiquitin ligase inhibitor activity" version="SP_139"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4AEZ" version="SP_139"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013212" version="SP_139"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1269284" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033597" secondary="mitotic checkpoint complex" version="SP_139"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011990" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007094" secondary="mitotic spindle assembly checkpoint signaling" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_139"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_588043.2"/>
                    <secondaryRef db="ensemblfungi" id="SPCC1795.01c.1" version="SP_139" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000776" secondary="kinetochore" version="SP_139"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015661" version="SP_139"/>
                    <secondaryRef db="ensemblfungi" id="SPCC1795.01c" version="SP_139" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045841" secondary="negative regulation of mitotic metaphase/anaphase transition" version="SP_139"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="284812">
                    <names>
                        <shortLabel>schpo</shortLabel>
                        <fullName>Schizosaccharomyces pombe (strain ATCC 38366 / 972)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                    </names>
                </organism>
                <sequence>MEPLDAGKNWVHMDVIEQSKENIEPRKAGHSASALAKSSSRNHTEKEVAGLQKERMGHERKIETSESLDDPLQVWIDYIKWTLDNFPQGETKTSGLVTLLERCTREFVRNPLYKDDVRYLRIWMQYVNYIDEPVELFSFLAHHHIGQESSIFYEEYANYFESRGLFQKADEVYQKGKRMKAKPFLRFQQKYQQFTHRWLEFAPQSFSSNTNSVNPLQTTFESTNIQEISQSRTKISKPKFKFSVYSDADGSGKDGQPGTWQTLGTVDQRRKENNISATSWVGEKLPLKSPRKLDPLGKFQVHCDEEVSKE</sequence>
                <attributeList>
                    <attribute name="crc64">EEC3EA6D3790C4BF</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-16942-1" id="1021586">
                <names>
                    <shortLabel>mad3-mad2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-3647420" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16942-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1021583</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1021587">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-3647422" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1021584</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1021588">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-3647421" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1021585</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1021589">
                                <names>
                                    <shortLabel>c-terminus</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-3647423" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>gfp tag</shortLabel>
                                        <fullName>green fluorescent protein tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">GFP</alias>
                                        <alias typeAc="MI:0303" type="go synonym">green fluorescent protein</alias>
                                        <alias typeAc="MI:1041" type="synonym">GFP</alias>
                                        <alias typeAc="MI:1041" type="synonym">green fluorescent protein</alias>
                                        <alias typeAc="MI:1041" type="synonym">gfp tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0367" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7491768" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608965" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">The interaction requires ask1 expression to occur.</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">Fig. 4B</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
