MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint li-2003g-1 Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon). in vitro In vitro phosphatase assay phosphatase assay predetermined predetermined participant predetermined Li MG., Katsura K., Nomiyama H., Komaki K., Ninomiya-Tsuji J., Matsumoto K., Kobayashi T., Tamura S. J. Biol. Chem. (0021-9258) 2003 partial coverage rapid curation li-2003g-2 Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon). human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Li MG., Katsura K., Nomiyama H., Komaki K., Ninomiya-Tsuji J., Matsumoto K., Kobayashi T., Tamura S. J. Biol. Chem. (0021-9258) 2003 partial coverage rapid curation ppm1l_mouse Protein phosphatase 1L Protein phosphatase 1-like Protein phosphatase 2C isoform epsilon Ppm1l Kiaa4175 protein protein mouse Mus musculus Mouse MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKSHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLTYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEH mint homomint Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6 mark3_human MAP/microtubule affinity-regulating kinase 3 Cdc25C-associated protein kinase 1 C-TAK1 Serine/threonine-protein kinase p78 Ser/Thr protein kinase PAR-1 Protein kinase STK10 MARK3 CTAK1 EMK2 ELKL motif kinase 2 protein protein human Homo sapiens Human MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL ppm1b_human Protein phosphatase 1B Protein phosphatase 2C isoform beta PPM1B PP2CB protein protein human Homo sapiens Human MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI mark3-ppm1l 1230397 ppm1l_mouse pp2c epsilon 1230399 enzyme enzyme neutral component neutral component mark3_human TAK1 1230400 enzyme target enzyme target substrate substrate neutral component neutral component physical association physical association false false false f4b homomint mint mark3-ppm1b 1230397 mark3_human TAK1 1230400 enzyme target enzyme target substrate substrate neutral component neutral component ppm1b_human PP2C beta 1230401 enzyme enzyme neutral component neutral component physical association physical association false false false f4a homomint mint mark3-ppm1l-1 1230397 ppm1l_mouse pp2c epsilon 1230399 enzyme enzyme neutral component neutral component mark3_human TAK1 1230400 enzyme target enzyme target substrate substrate neutral component neutral component Resulting Phenotypic qualities (properties)[PATO]: PATO:0002221 (increased phosphorylation) physical association physical association false false false f5 homomint mint mark3-ppm1l-2 1230398 ppm1l_mouse pp2c epsilon 1230399 unspecified role unspecified role prey prey mark3_human TAK1 1230400 unspecified role unspecified role bait bait physical association physical association false false false f6a homomint mint