UniProt UniProt http://www.uniprot.org majoul-2001-1 KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET. chlae-vero Chlorocebus (Cercopithecus) aethiops kidney cells Grivet vero Chlorocebus (Cercopithecus) aethiops kidney cells similar to cos-7 cells but these are not trasnformed fret fluorescent resonance energy transfer FRET RET FRET analysis FRET RET FRET analysis fret tag fluorescence tag visualisation by fluorescence tag fluorescence Majoul I., Straub M., Hell S.W., Duden R., Soling H.D. Origin of KDELR1/ERD2 as human according pmid:9074641 hsoelin@gwdg.de Dev. Cell (1534-5807) 2001 mimix curation majoul-2001-2 KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET. chlae-vero Chlorocebus (Cercopithecus) aethiops kidney cells Grivet vero Chlorocebus (Cercopithecus) aethiops kidney cells similar to cos-7 cells but these are not trasnformed fluorescence imaging fluorescence microscopy fluorescence imaging anti tag immunost anti tag immunostaining anti tag immunost Majoul I., Straub M., Hell S.W., Duden R., Soling H.D. Origin of KDELR1/ERD2 as human according pmid:9074641 hsoelin@gwdg.de Dev. Cell (1534-5807) 2001 mimix curation chta_vibch Cholera enterotoxin subunit A ctxA toxA VC_1457 Cholera enterotoxin, A chain protein protein vibch Vibrio cholerae MVKIIFVFFIFLSSFSYANDDKLYRADSRPPDEIKQSGGLMPRGQSEYFDRGTQMNINLYDHARGTQTGFVRHDDGYVSTSISLRSAHLVGQTILSGHSTYYIYVIATAPNMFNVNDVLGAYSPHPDEQEVSALGGIPYSQIYGWYRVHFGVLDEQLHRNRGYRDRYYSNLDIAPAADGYGLAGFPPEHRAWREEPWIHHAPPGCGNAPRSSMSNTCDEKTQSLGVKFLDEYQSKVKRQIFSGYQSDIDTHNRIKDEL erd21_human ER lumen protein-retaining receptor 1 KDELR1 ERD2.1 KDEL endoplasmic reticulum protein retention receptor 1 Putative MAPK-activating protein PM23 protein protein human Homo sapiens Human MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA arfg1_rat ADP-ribosylation factor GTPase-activating protein 1 Arfgap1 Arf1gap ADP-ribosylation factor 1 GTPase-activating protein ARF1-directed GTPase-activating protein protein protein rat Rattus norvegicus (Rat) Rat MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW arf1_bovin ADP-ribosylation factor 1 ARF1 protein protein bovin Bos taurus (Bovine) Bovine MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK tmeda_rat Transmembrane emp24 domain-containing protein 10 21 kDa transmembrane-trafficking protein Transmembrane protein Tmp21 Tmed10 Tmp21 p24 family protein delta-1 protein protein rat Rattus norvegicus (Rat) Rat MSGLSGPLSWPGPLLSALLFLFLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE tmed2_human Transmembrane emp24 domain-containing protein 2 TMED2 RNP24 Membrane protein p24A p24 family protein beta-1 p24 protein protein human Homo sapiens Human MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV copb_rat Coatomer subunit beta Beta-coat protein Copb1 Copb protein protein rat Rattus norvegicus (Rat) Rat MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFENLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNVTDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL ctxa-kdelr1 1182071 n/a 1182073 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept n/a 1182074 unspecified role unspecified role fluorescence donor fluorescence donor proximity proximity close-contact colocalization neighbourhood interaction false false false 2c kdelr1-kdelr1 1182071 n/a 1182074 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept n/a 1182074 unspecified role unspecified role fluorescence donor fluorescence donor proximity proximity close-contact colocalization neighbourhood interaction false false false 2e Induced by KDELR1/ERD2 ligand arfgap1-kdelr1 1182071 n/a 1182075 unspecified role unspecified role fluorescence donor fluorescence donor n/a 1182074 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept proximity proximity close-contact colocalization neighbourhood interaction false false false 3c and d Induced by KDELR1/ERD2 ligand arf1-kdelr1 1182071 n/a 1182076 unspecified role unspecified role fluorescence donor fluorescence donor n/a 1182074 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept proximity proximity close-contact colocalization neighbourhood interaction false false false 4c Enhanced by KDELR1/ERD2 ligand tmed10-tmed2-2 1182071 n/a 1182077 unspecified role unspecified role fluorescence donor fluorescence donor n/a 1182078 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept proximity proximity close-contact colocalization neighbourhood interaction false false false 4d Not affected by KDELR1/ERD2 ligand arf1-arfgap1 1182071 n/a 1182076 unspecified role unspecified role fluorescence donor fluorescence donor n/a 1182075 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept proximity proximity close-contact colocalization neighbourhood interaction false false false 4b and c Requires ligand binding to KDELR1/ERD2 kdelr1-tmed10 1182071 n/a 1182074 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept n/a 1182077 unspecified role unspecified role fluorescence donor fluorescence donor proximity proximity close-contact colocalization neighbourhood interaction false false false 6 Impaired by KDELR1/ERD2 ligand copb1-kdelr1 1182071 n/a 1182079 unspecified role unspecified role fluorescence donor fluorescence donor n/a 1182074 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept proximity proximity close-contact colocalization neighbourhood interaction false false false 7a Impaired by KDELR1/ERD2 ligand arf1-tmed10 1182071 n/a 1182076 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept n/a 1182077 unspecified role unspecified role fluorescence donor fluorescence donor proximity proximity close-contact colocalization neighbourhood interaction false false false 7b arf1-tmed2 1182071 n/a 1182078 unspecified role unspecified role fluorescence donor fluorescence donor n/a 1182076 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept proximity proximity close-contact colocalization neighbourhood interaction false false false 7c arfgap1-tmed2 1182071 n/a 1182075 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept n/a 1182078 unspecified role unspecified role fluorescence donor fluorescence donor proximity proximity close-contact colocalization neighbourhood interaction false false false 7e kdelr1-kdelr1-1 1182072 n/a 1182074 unspecified role unspecified role neutral component neutral component n/a 1182074 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2a