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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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                <names>
                    <shortLabel>wang-2010m-1</shortLabel>
                    <fullName>Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development.</fullName>
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                            <shortLabel>mouse-t-cell</shortLabel>
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                                <shortLabel>t-cell</shortLabel>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
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                        <fullName>predetermined participant</fullName>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang H., Holst J., Woo SR., Guy C., Bettini M., Wang Y., Shafer A., Naramura M., Mingueneau M., Dragone LL., Hayes SM., Malissen B., Band H., Vignali DA.</attribute>
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                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
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            <experimentDescription id="917875">
                <names>
                    <shortLabel>wang-2010m-2</shortLabel>
                    <fullName>Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development.</fullName>
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                            <shortLabel>mouse-t-cell</shortLabel>
                            <fullName>Mouse T cell</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>t-cell</shortLabel>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>facs</shortLabel>
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                        <alias typeAc="MI:0303" type="go synonym">FACS</alias>
                        <alias typeAc="MI:0303" type="go synonym">Flow cytometry</alias>
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            <experimentDescription id="917876">
                <names>
                    <shortLabel>wang-2010m-3</shortLabel>
                    <fullName>Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development.</fullName>
                </names>
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                        <names>
                            <shortLabel>mouse-t-cell</shortLabel>
                            <fullName>Mouse T cell</fullName>
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                            <names>
                                <shortLabel>t-cell</shortLabel>
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                        <shortLabel>fluorescence imaging</shortLabel>
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                    <attribute name="author-list" nameAc="MI:0636">Wang H., Holst J., Woo SR., Guy C., Bettini M., Wang Y., Shafer A., Naramura M., Mingueneau M., Dragone LL., Hayes SM., Malissen B., Band H., Vignali DA.</attribute>
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        <interactorList>
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                    <shortLabel>cd3z_mouse</shortLabel>
                    <fullName>T-cell surface glycoprotein CD3 zeta chain</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">Tcrz</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T-cell receptor T3 zeta chain</alias>
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                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
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                    </names>
                </organism>
                <sequence>MKWKVSVLACILHVRFPGAEAQSFGLLDPKLCYLLDGILFIYGVIITALYLRAKFSRSAETAANLQDPNQLYNELNLGRREEYDVLEKKRARDPEMGGKQQRRRNPQEGVYNALQKDKMAEAYSEIGTKGERRRGKGHDGLYQGLSTATKDTYDALHMQTLAPR</sequence>
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                    <shortLabel>ubiq_mouse</shortLabel>
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                    <alias typeAc="MI:0301" type="gene name">Ubc</alias>
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                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_889611.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9CXY4" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-413074" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000008348"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000058838"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019956"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q91887" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000626" secondary="Ubiquitin"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000068240"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001029037.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3A9J"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29742N" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9D8D9" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019955"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9ET23" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ZNV"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_001481004.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634"/>
                    <secondaryRef db="ipi" dbAc="MI:0675" id="IPI00750889"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9D1R5" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q91888" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P02250" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000019505"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q64223" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005515"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8VCH1" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG</sequence>
            </interactor>
            <interactor id="917879">
                <names>
                    <shortLabel>cd3e_mouse</shortLabel>
                    <fullName>T-cell surface glycoprotein CD3 epsilon chain</fullName>
                    <alias typeAc="MI:0301" type="gene name">Cd3e</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T-cell surface antigen T3/Leu-4 epsilon chain</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P22646" version="SP_92" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042101" secondary="T cell receptor complex" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001772" secondary="immunological synapse" version="SP_180"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202433" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001954" secondary="positive regulation of cell-matrix adhesion" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005911" secondary="cell-cell junction" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002669" secondary="positive regulation of T cell anergy" version="SP_180"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" secondary="external side of plasma membrane" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042105" secondary="alpha-beta T cell receptor complex" version="SP_180"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JBJ" version="SP_180"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XMW" version="SP_180"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202427" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007584" secondary="response to nutrient" version="SP_180"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-7895702" refType="intact-secondary"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3R08" version="SP_180"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000099896" version="SP_180" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" secondary="protein heterodimerization activity" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" secondary="apoptotic signaling pathway" version="SP_180"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-389948" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_180"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202424" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045879" secondary="negative regulation of smoothened signaling pathway" version="SP_180"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-198933" version="SP_180"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P22646" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046641" secondary="positive regulation of alpha-beta T cell proliferation" version="SP_180"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202430" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" secondary="endoplasmic reticulum" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017124" secondary="SH3 domain binding" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045060" secondary="negative thymic T cell selection" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050870" secondary="positive regulation of T cell activation" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045059" secondary="positive thymic T cell selection" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_180"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_031674.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_180"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032753" secondary="positive regulation of interleukin-4 production" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_180"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803432" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002250" secondary="adaptive immune response" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050852" secondary="T cell receptor signaling pathway" version="SP_180"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003110" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021549" secondary="cerebellum development" version="SP_180"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000032093" version="SP_180" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015484" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016358" secondary="dendrite development" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043197" secondary="dendritic spine" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046649" secondary="lymphocyte activation" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042102" secondary="positive regulation of T cell proliferation" version="SP_180"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2K4F" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007166" secondary="cell surface receptor signaling pathway" version="SP_180"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003598" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044297" secondary="cell body" version="SP_180"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006510029.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050731" secondary="positive regulation of peptidyl-tyrosine phosphorylation" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032743" secondary="positive regulation of interleukin-2 production" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033634" secondary="positive regulation of cell-cell adhesion mediated by integrin" version="SP_180"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_180"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050850" secondary="positive regulation of calcium-mediated signaling" version="SP_180"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000102832" version="SP_180" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031295" secondary="T cell costimulation" version="SP_180"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MRWNTFWGILCLSLLAVGTCQDDAENIEYKVSISGTSVELTCPLDSDENLKWEKNGQELPQKHDKHLVLQDFSEVEDSGYYVCYTPASNKNTYLYLKARVCEYCVEVDLTAVAIIIIVDICITLGLLMVIYYWSKNRKAKAKPVTRGTGAGSRPRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRAV</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="917880">
                <names>
                    <shortLabel>cd4_mouse</shortLabel>
                    <fullName>T-cell surface glycoprotein CD4</fullName>
                    <alias typeAc="MI:0301" type="gene name">Cd4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T-cell surface antigen T4/Leu-3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T-cell differentiation antigen L3T4</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P06332" version="SP_87" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000024044" version="SP_202" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002250" secondary="adaptive immune response" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990782" secondary="protein tyrosine kinase binding" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015274" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015026" secondary="coreceptor activity" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013151" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_202"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P06332" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045860" secondary="positive regulation of protein kinase activity" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202430" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007155" secondary="cell adhesion" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046598" secondary="positive regulation of viral entry into host cell" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_038516.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050863" secondary="regulation of T cell activation" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042289" secondary="MHC class II protein binding" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1462054" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007166" secondary="cell surface receptor signaling pathway" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050850" secondary="positive regulation of calcium-mediated signaling" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035397" secondary="helper T cell enhancement of adaptive immune response" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR021963" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0023026" secondary="MHC class II protein complex binding" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-449836" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050731" secondary="positive regulation of peptidyl-tyrosine phosphorylation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019865" secondary="immunoglobulin binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000973" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051924" secondary="regulation of calcium ion transport" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202433" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8856828" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000024044" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005788" secondary="endoplasmic reticulum lumen" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030225" secondary="macrophage differentiation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045058" secondary="T cell selection" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042012" secondary="interleukin-16 receptor activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" secondary="external side of plasma membrane" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010524" secondary="positive regulation of calcium ion transport into cytosol" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006948" secondary="induction by virus of host cell-cell fusion" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042102" secondary="positive regulation of T cell proliferation" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000023274" version="SP_202" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097011" secondary="cellular response to granulocyte macrophage colony-stimulating factor stimulus" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202427" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035723" secondary="interleukin-15-mediated signaling pathway" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045657" secondary="positive regulation of monocyte differentiation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032507" secondary="maintenance of protein location in cell" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202424" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008424" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042011" secondary="interleukin-16 binding" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013106" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8856825" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042110" secondary="T cell activation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_202"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1404" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050870" secondary="positive regulation of T cell activation" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-389948" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030217" secondary="T cell differentiation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_202"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MCRAISLRRLLLLLLQLSQLLAVTQGKTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKEEVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSKVLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQSTAITAYKSEGESAEFSFPLNFAEENGWGELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDKGTLHQEVNLVVMKVAQLNNTLTCEVMGPTSPKMRLTLKQENQEARVSEEQKVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVNQTVFLACVLGGSFGFLGFLGLCILCCVRCRHQQRQAARMSQIKRLLSEKKTCQCPHRMQKSHNLI</sequence>
            </interactor>
            <interactor id="917881">
                <names>
                    <shortLabel>cd8a_mouse</shortLabel>
                    <fullName>T-cell surface glycoprotein CD8 alpha chain</fullName>
                    <alias typeAc="MI:0301" type="gene name">Cd8a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Lyt-2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Lyt2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T-cell surface glycoprotein Lyt-2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P01731" version="SP_89" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013106" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0023024" secondary="MHC class I protein complex binding" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DMM" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042110" secondary="T cell activation" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007166" secondary="cell surface receptor signaling pathway" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1BQH" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015468" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-198933" version="SP_194"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P01731" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ARJ" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002456" secondary="T cell mediated immunity" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050850" secondary="positive regulation of calcium-mediated signaling" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3B9K" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ATP" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_194"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001074579.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_194"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1433" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000066747" version="SP_194" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000068123" version="SP_194" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045065" secondary="cytotoxic T cell differentiation" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" secondary="defense response to virus" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NEZ" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044853" secondary="plasma membrane raft" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" secondary="external side of plasma membrane" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_194"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000053977" version="SP_194" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_194"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MASPLTRFLSLNLLLLGESIILGSGEAKPQAPELRIFPKKMDAELGQKVDLVCEVLGSVSQGCSWLFQNSSSKLPQPTFVVYMASSHNKITWDEKLNSSKLFSAMRDTNNKYVLTLNKFSKENEGYYFCSVISNSVMYFSSVVPVLQKVNSTTTKPVLRTPSPVHPTGTSQPQRPEDCRPRGSVKGTGLDFACDIYIWAPLAGICVALLLSLIITLICYHRSRKRVCKCPRPLVRQEGKPRPSEKIV</sequence>
            </interactor>
            <interactor id="917882">
                <names>
                    <shortLabel>lapm5_mouse</shortLabel>
                    <fullName>Lysosomal-associated transmembrane protein 5</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Lysosomal-associated multitransmembrane protein 5</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Retinoic acid-inducible E3 protein</alias>
                    <alias typeAc="MI:0301" type="gene name">Laptm5</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q61168" version="SP_50" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000028581" version="SP_147" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060907" secondary="positive regulation of macrophage cytokine production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005765" secondary="lysosomal membrane" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140311" secondary="protein sequestering activity" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050860" secondary="negative regulation of T cell receptor signaling pathway" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032703" secondary="negative regulation of interleukin-2 production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_147"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-911973" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032689" secondary="negative regulation of interferon-gamma production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032735" secondary="positive regulation of interleukin-12 production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030133" secondary="transport vesicle" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000060" secondary="positive regulation of ubiquitin-dependent protein catabolic process" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061462" secondary="protein localization to lysosome" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002357" secondary="defense response to tumor cell" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031398" secondary="positive regulation of protein ubiquitination" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097214" secondary="positive regulation of lysosomal membrane permeability" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018396" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050869" secondary="negative regulation of B cell activation" version="SP_147"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-37698N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903052" secondary="positive regulation of proteolysis involved in cellular protein catabolic process" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000646" secondary="positive regulation of receptor catabolic process" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018397" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903265" secondary="positive regulation of tumor necrosis factor-mediated signaling pathway" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140036" secondary="ubiquitin-dependent protein binding" version="SP_147"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000151698" version="SP_147" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0012502" secondary="induction of programmed cell death" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005764" secondary="lysosome" version="SP_147"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q60923" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006886" secondary="intracellular protein transport" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050868" secondary="negative regulation of T cell activation" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004687" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904093" secondary="negative regulation of autophagic cell death" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090160" secondary="Golgi to lysosome transport" version="SP_147"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017175490.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990830" secondary="cellular response to leukemia inhibitory factor" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006622" secondary="protein targeting to lysosome" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140646" secondary="negative regulation of pre-B cell receptor expression" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031410" secondary="cytoplasmic vesicle" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046007" secondary="negative regulation of activated T cell proliferation" version="SP_147"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_034816.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000118415" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002720" secondary="positive regulation of cytokine production involved in immune response" version="SP_147"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q61168" version="SP_147"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MASRAAPVRQTCCCFNIRVATIALAIYHIVMSVLLFIEHVVEVARGKVSCRFFKMPYLRMADLLSSFLLIGVLFIISISLLFGVVKNREKYLIPFLSLQIMDFLLCLLTLLGSYIELPAYLKLARPRPGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEGVPHSQFINMMLIFSVAFITVLILKVYMFKCVYTCYKFLKHMNSAMEDSSSKMFLKVALPSYEEALSLPPKTPEGDPAPPPYSEV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-15082-3" id="917883">
                <names>
                    <shortLabel>cd247-rps27a</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895679" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15082-3" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803421" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>917874</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="917884">
                        <names>
                            <shortLabel>cd3z_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CD3 zeta</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895681" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803426" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917877</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="917885">
                        <names>
                            <shortLabel>ubiq_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ubiquitin</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895682" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803429" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917878</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">f1a f1d f1f f2e f3d f5b fs4 fs5b</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-15082-4" id="917886">
                <names>
                    <shortLabel>cd3e-rps27a</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895735" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803469" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15082-4" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>917874</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="917887">
                        <names>
                            <shortLabel>cd3e_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CD3 epsilon</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895737" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803477" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917879</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>cell lysate</shortLabel>
                                    <fullName>cell lysate</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0344" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537757" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="917888">
                        <names>
                            <shortLabel>ubiq_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ubiquitin</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895739" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803474" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917878</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>cell lysate</shortLabel>
                                    <fullName>cell lysate</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0344" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537757" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f1b</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-15082-2" id="917889">
                <names>
                    <shortLabel>cd4-cd8a</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895789" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803506" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" refType="go-definition-ref" refTypeAc="MI:0242"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15082-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>917875</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="917890">
                        <names>
                            <shortLabel>cd4_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CD4</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895792" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803516" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917880</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="917891">
                        <names>
                            <shortLabel>cd8a_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CD8</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895791" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803513" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917881</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">f2b f3a</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-15082-1" id="917892">
                <names>
                    <shortLabel>cd247-laptm5</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895824" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803528" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15082-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" refType="go-definition-ref" refTypeAc="MI:0242"/>
                </xref>
                <experimentList>
                    <experimentRef>917876</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="917893">
                        <names>
                            <shortLabel>cd3z_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CD3 zeta</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895827" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803538" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917877</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>fixed cell</shortLabel>
                                    <fullName>fixed cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0348" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="917894">
                        <names>
                            <shortLabel>lapm5_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Laptm5</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7895826" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7803535" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>917882</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>fixed cell</shortLabel>
                                    <fullName>fixed cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0348" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">fs3</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
