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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="910506">
                <names>
                    <shortLabel>drosten-2010-1</shortLabel>
                    <fullName>Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="20150892" refType="primary-reference" refTypeAc="MI:0358"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-embryonic_fibroblast</shortLabel>
                            <fullName>Mus musculus embryonic fibroblasts</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>embryonic_fibroblast</shortLabel>
                                <fullName>Embryonic fibroblast</fullName>
                            </names>
                            <xref>
                                <primaryRef db="mint" dbAc="MI:0471" id="MINT-2983518" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="brenda" dbAc="MI:0864" id="BTO:0004725" refType="identity" refTypeAc="MI:0356"/>
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                            <attributeList>
                                <attribute name="comment" nameAc="MI:0612">Fibroblasts taken from an embryonic as opposed to a foetal or adult source. Foetus is defined as the stage at which tissue diferentiation is initiated.</attribute>
                                <attribute name="comment" nameAc="MI:0612">Tissue taken from an embryonic as opposed to a foetal or adult source. Embryo is defined as the development stage prior to organ formation.</attribute>
                            </attributeList>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Drosten M., Dhawahir A., Sum EY., Urosevic J., Lechuga CG., Esteban LM., Castellano E., Guerra C., Santos E., Barbacid M.</attribute>
                    <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
                    <attribute name="imex-exported"/>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="910507">
                <names>
                    <shortLabel>ccnd1_mouse</shortLabel>
                    <fullName>G1/S-specific cyclin-D1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ccnd1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cyl-1</alias>
                </names>
                <xref>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-187577" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031965" secondary="nuclear membrane" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033601" secondary="positive regulation of mammary gland epithelial cell proliferation" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070064" secondary="proline-rich region binding" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045737" secondary="positive regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900087" secondary="positive regulation of G1/S transition of mitotic cell cycle" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016538" secondary="cyclin-dependent protein serine/threonine kinase regulator activity" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097421" secondary="liver regeneration" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042826" secondary="histone deacetylase binding" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032026" secondary="response to magnesium ion" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8849470" version="SP_194"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004367" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030968" secondary="endoplasmic reticulum unfolded protein response" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010243" secondary="response to organonitrogen compound" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016055" secondary="Wnt signaling pathway" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006671" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000079" secondary="regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045444" secondary="fat cell differentiation" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017053" secondary="transcription repressor complex" version="SP_194"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8934593" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013763" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030857" secondary="negative regulation of epithelial cell differentiation" version="SP_194"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MEHQLLCCEVETIRRAYPDTNLLNDRVLRAMLKTEETCAPSVSYFKCVQKEIVPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQTIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTTHFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNVDPKATEEEGEVEEEAGLACTPTDVRDVDI</sequence>
            </interactor>
            <interactor id="910508">
                <names>
                    <shortLabel>cdk4_mouse</shortLabel>
                    <fullName>Cyclin-dependent kinase 4</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Cell division protein kinase 4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PSK-J3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CRK3</alias>
                    <alias typeAc="MI:0301" type="gene name">Cdk4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Crk3</alias>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060612" secondary="adipose tissue development" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008353" secondary="RNA polymerase II CTD heptapeptide repeat kinase activity" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" secondary="transcription regulator complex" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_199"/>
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                    <secondaryRef db="mint" dbAc="MI:0471" id="P30285" version="SP_199"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097129" secondary="cyclin D2-CDK4 complex" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106310" secondary="protein serine kinase activity" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000082" secondary="G1/S transition of mitotic cell cycle" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010033" secondary="response to organic substance" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050994" secondary="regulation of lipid catabolic process" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_199"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000006911" version="SP_199" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008271" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" secondary="protein kinase activity" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046626" secondary="regulation of insulin receptor signaling pathway" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8849470" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9616222" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004693" secondary="cyclin-dependent protein serine/threonine kinase activity" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031100" secondary="animal organ regeneration" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002088" secondary="lens development in camera-type eye" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904628" secondary="cellular response to phorbol 13-acetate 12-myristate" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016301" secondary="kinase activity" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0040014" secondary="regulation of multicellular organism growth" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045727" secondary="positive regulation of translation" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007623" secondary="circadian rhythm" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" secondary="regulation of cell cycle" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048146" secondary="positive regulation of fibroblast proliferation" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-75815" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033574" secondary="response to testosterone" version="SP_199"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPREVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEESDAE</sequence>
            </interactor>
            <interactor id="910509">
                <names>
                    <shortLabel>cdk2_mouse</shortLabel>
                    <fullName>Cyclin-dependent kinase 2</fullName>
                    <alias typeAc="MI:0301" type="gene name">Cdk2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cell division protein kinase 2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cdkn2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P97377" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097135" secondary="cyclin E2-CDK2 complex" version="SP_197"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24176N"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-176408" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804756" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051321" secondary="meiotic cell cycle" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-187577" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" secondary="regulation of gene expression" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106311" secondary="protein threonine kinase activity" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030332" secondary="cyclin binding" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000806" secondary="Y chromosome" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000287" secondary="magnesium ion binding" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000805" secondary="X chromosome" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2559582" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097123" secondary="cyclin A1-CDK2 complex" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-68949" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006813" secondary="potassium ion transport" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-171319" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_197"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_058036.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5693607" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69200" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69273" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69656" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000307" secondary="cyclin-dependent protein kinase holoenzyme complex" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010389" secondary="regulation of G2/M transition of mitotic cell cycle" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051591" secondary="response to cAMP" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060968" secondary="regulation of gene silencing" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097124" secondary="cyclin A2-CDK2 complex" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804757" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032869" secondary="cellular response to insulin stimulus" version="SP_197"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-847048" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" secondary="transcription regulator complex" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_197"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000026416" version="SP_197" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097134" secondary="cyclin E1-CDK2 complex" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1538133" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674" secondary="protein serine/threonine kinase activity" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69231" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008271" version="SP_197"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O55105" version="SP_67" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69017" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018105" secondary="peptidyl-serine phosphorylation" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000082" secondary="G1/S transition of mitotic cell cycle" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-68911" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9616222" version="SP_197"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_904326.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097472" secondary="cyclin-dependent protein kinase activity" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69563" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032298" secondary="positive regulation of DNA-dependent DNA replication initiation" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804116" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004693" secondary="cyclin-dependent protein serine/threonine kinase activity" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69202" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" secondary="protein kinase activity" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-68962" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8849470" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016572" secondary="histone phosphorylation" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2559586" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051602" secondary="response to electrical stimulus" version="SP_197"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P97377" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016301" secondary="kinase activity" version="SP_197"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000025358" version="SP_197" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000793" secondary="condensed chromosome" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106310" secondary="protein serine kinase activity" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006281" secondary="DNA repair" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-176187" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007099" secondary="centriole replication" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015030" secondary="Cajal body" version="SP_197"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000026416" version="SP_197" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSAPHPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL</sequence>
            </interactor>
            <interactor id="910510">
                <names>
                    <shortLabel>ccne1_mouse</shortLabel>
                    <fullName>G1/S-specific cyclin-E1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ccne1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ccne</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q61457" version="SP_59" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q05BA1" version="SP_66" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000082" secondary="G1/S transition of mitotic cell cycle" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036915" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_172"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000103658" version="SP_172" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69563" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69202" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804116" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016301" secondary="kinase activity" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8849470" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028858" version="SP_172"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-643090" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69017" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000723" secondary="telomere maintenance" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2559586" version="SP_172"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q05BB7" version="SP_66" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004367" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902462" secondary="positive regulation of mesenchymal stem cell proliferation" version="SP_172"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-45868N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070192" secondary="chromosome organization involved in meiotic cell cycle" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_031659.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016055" secondary="Wnt signaling pathway" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006671" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000079" secondary="regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9706019" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013763" version="SP_172"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000002068" version="SP_172" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044772" secondary="mitotic cell cycle phase transition" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-187577" version="SP_172"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q05BA6" version="SP_66" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_172"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q61457" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045597" secondary="positive regulation of cell differentiation" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" secondary="regulation of cell cycle" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016538" secondary="cyclin-dependent protein serine/threonine kinase regulator activity" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903827" secondary="regulation of cellular protein localization" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039361" version="SP_172"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000108023" version="SP_172" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007129" secondary="homologous chromosome pairing at meiosis" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69200" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000307" secondary="cyclin-dependent protein kinase holoenzyme complex" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006270" secondary="DNA replication initiation" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1538133" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69231" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097134" secondary="cyclin E1-CDK2 complex" version="SP_172"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MPRERDSTDHSNMKEEGGSDLSVRSRKRKANVAVFLQDPDEEIAKIDKTVKSEDSSQPWDDNSACVDPCSFIPTPNKEEDNELEYPRTAFQPRKIRPPRASPLPVLNWGNREEVWRIMLNKEKTYLRDEHFLQRHPLLQARMRAVLLDWLMEVCEVYKLHRETFYLAQDFFDRYMASQHNIIKTLLQLIGISALFIASKLEEIYPPKLHQFAYVTDGACSGDEILTMELMMMKALKWRLSPLTIVSWLNVYVQVAYVNDTGEVLMPQYPQQVFVQIAELLDLCVLDVGCLEFPYGVLAASALYHFSSLELMQKVSGYQWCDIEKCVKWMVPFAMVIREMGSSKLKHFRGVPMEDSHNIQTHTNSLDLLDKAQAKKAILSEQNRISPPPSVVLTPPPSSKKQSSEQETE</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-15100-1" id="910511">
                <names>
                    <shortLabel>ccnd1-cdk4-13</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-7893437" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7800636" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15100-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>910506</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="910512">
                        <names>
                            <shortLabel>ccnd1_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Cyclin D1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7893439" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7800644" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>910507</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="910513">
                        <names>
                            <shortLabel>cdk4_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Cdk4</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7893440" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7800641" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>910508</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">f8b</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-15100-2" id="910514">
                <names>
                    <shortLabel>ccne1-cdk2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-7893446" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15100-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7800665" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>910506</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="910515">
                        <names>
                            <shortLabel>cdk2_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Cdk2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7893450" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7800674" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>910509</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="910516">
                        <names>
                            <shortLabel>ccne1_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Cyclin E1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-7893448" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7800671" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>910510</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">f8b</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
