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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
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            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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        </source>
        <experimentList>
            <experimentDescription id="986078">
                <names>
                    <shortLabel>maekawa-2006-1</shortLabel>
                    <fullName>Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury.</fullName>
                </names>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-3">
                        <names>
                            <shortLabel>unknown</shortLabel>
                            <fullName>Unknown</fullName>
                        </names>
                    </hostOrganism>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>coip</shortLabel>
                        <fullName>coimmunoprecipitation</fullName>
                        <alias typeAc="MI:0303" type="go synonym">co-immunoprecipitation</alias>
                        <alias typeAc="MI:0303" type="go synonym">CoIp</alias>
                        <alias typeAc="MI:0303" type="go synonym">immunoprecipitation</alias>
                        <alias typeAc="MI:0303" type="go synonym">Co-IP</alias>
                        <alias typeAc="MI:1041" type="synonym">co-immunoprecipitation</alias>
                        <alias typeAc="MI:1041" type="synonym">CoIp</alias>
                        <alias typeAc="MI:1041" type="synonym">immunoprecipitation</alias>
                        <alias typeAc="MI:1041" type="synonym">Co-IP</alias>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Maekawa N., Abe J., Shishido T., Itoh S., Ding B., Sharma VK., Sheu SS., Blaxall BC., Berk BC.</attribute>
                    <attribute name="journal" nameAc="MI:0885">Circulation (0009-7322)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2006</attribute>
                    <attribute name="partial coverage" nameAc="MI:0958">partial coverage</attribute>
                    <attribute name="rapid curation" nameAc="MI:0961">rapid curation</attribute>
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            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="986079">
                <names>
                    <shortLabel>1433b_human</shortLabel>
                    <fullName>14-3-3 protein beta/alpha</fullName>
                    <alias typeAc="MI:0301" type="gene name">YWHAB</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein kinase C inhibitor protein 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein 1054</alias>
                </names>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
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                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN</sequence>
            </interactor>
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                <names>
                    <shortLabel>sl9a1_human</shortLabel>
                    <fullName>Sodium/hydrogen exchanger 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Na(+)/H(+) exchanger 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Solute carrier family 9 member 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Na(+)/H(+) antiporter, amiloride-sensitive</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">APNH</alias>
                    <alias typeAc="MI:0301" type="gene name">SLC9A1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">APNH1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">NHE1</alias>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030011" secondary="maintenance of cell polarity" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2HTG" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_226"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B1ALD6" version="SP_114" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071872" secondary="cellular response to epinephrine stimulus" version="SP_226"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000090020" version="SP_226" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_226"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006153" version="SP_226"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004709" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y4E" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7DSW" version="SP_226"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P19634" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010882" secondary="regulation of cardiac muscle contraction by calcium ion signaling" version="SP_226"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2160916" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_226"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DPL4" version="SP_124" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006883" secondary="cellular sodium ion homeostasis" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098719" secondary="sodium ion import across plasma membrane" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015385" secondary="sodium:proton antiporter activity" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051893" secondary="regulation of focal adhesion assembly" version="SP_226"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000263980" version="SP_226" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-743635" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048306" secondary="calcium-dependent protein binding" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051492" secondary="regulation of stress fiber assembly" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BJF" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030307" secondary="positive regulation of cell growth" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071257" secondary="cellular response to electrical stimulus" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902600" secondary="proton transmembrane transport" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2YGG" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060090" secondary="molecular adaptor activity" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7DSX" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006811" secondary="ion transport" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903281" secondary="positive regulation of calcium:sodium antiporter activity" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036376" secondary="sodium ion export across plasma membrane" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005546" secondary="phosphatidylinositol-4,5-bisphosphate binding" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010447" secondary="response to acidic pH" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071468" secondary="cellular response to acidic pH" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071805" secondary="potassium ion transmembrane transport" version="SP_226"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSEPPRERSIGDVTTAPPEVTPESRPVNHSVTDHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="986081">
                <names>
                    <shortLabel>slc9a1-ywhab-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8007529" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8529837" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>986078</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="986082">
                        <names>
                            <shortLabel>1433b_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">1433B_HUMAN</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8007530" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8529846" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P31946" refType="original identifier" refTypeAc="MI:0869"/>
                        </xref>
                        <interactorRef>986079</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="986083">
                        <names>
                            <shortLabel>sl9a1_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">SL9A1_HUMAN</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8007533" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P19634" refType="original identifier" refTypeAc="MI:0869"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8529842" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>986080</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">domino</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
