MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint hanson-2006-1 Visual arrestin binding to microtubules involves a distinct conformational change. in vitro In vitro biochemical biochemical predetermined predetermined participant predetermined Hanson SM., Francis DJ., Vishnivetskiy SA., Klug CS., Gurevich VV. J. Biol. Chem. (0021-9258) 2006 hanson-2006-2 Visual arrestin binding to microtubules involves a distinct conformational change. in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined Hanson SM., Francis DJ., Vishnivetskiy SA., Klug CS., Gurevich VV. J. Biol. Chem. (0021-9258) 2006 arrs_bovin S-arrestin SAG Retinal S-antigen 48 kDa protein Rod photoreceptor arrestin protein protein bovin Bos taurus (Bovine) Bovine MKANKPAPNHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHPQPEDPDTAKESFQDENFVFEEFARQNLKDAGEYKEEKTDQEAAMDE mint S-antigen induces autoimmune uveitis Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade tbb2b_bovin Tubulin beta-2B chain TUBB2B protein protein bovin Bos taurus (Bovine) Bovine MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA mint Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain tba4a_bovin Tubulin alpha-4A chain TUBA1 TUBA4A Tubulin alpha-1 chain Alpha-tubulin 1 protein protein bovin Bos taurus (Bovine) Bovine MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSYEDEDEGEE mint Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain sag-tuba4a 793783 arrs_bovin Arrestin 793785 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified tbb2b_bovin tubulin beta 793786 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified tba4a_bovin tubulin alpha 793787 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified association association false false false F1A homomint mint sag-tuba4a-1 793783 tbb2b_bovin tubulin beta 793786 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified arrs_bovin Arrestin 793785 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component in vitro translated in vitro translated protein in vitro translated tba4a_bovin tubulin alpha 793787 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified association association false false false homomint F1B F2 F3 F4 F5 mint sag-tuba4a-2 793784 tbb2b_bovin tubulin beta 793786 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified arrs_bovin Arrestin 793785 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified tba4a_bovin tubulin alpha 793787 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified physical association physical association false false false homomint F6 F7 F8 mint