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                    <shortLabel>papakonstan-2007-1</shortLabel>
                    <fullName>The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN.</fullName>
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                            <shortLabel>mouse-bmm</shortLabel>
                            <fullName>mouse bone marrow derived macrophages</fullName>
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                                <shortLabel>bmm</shortLabel>
                                <fullName>bone marrow derived macrophages</fullName>
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                                <attribute name="comment" nameAc="MI:0612">Bone marrow derived macrophages (BMM) were generated in vitro from precursor cells harvested from the femurs of C57BL/6 mice (7�8 weeks) by proliferation and differentiation in the presence of L-cell conditioned medium.  as a source of CSF-1</attribute>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
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                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Papakonstanti EA., Ridley AJ., Vanhaesebroeck B.</attribute>
                    <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="imex-exported">2009-01-08</attribute>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007229" secondary="integrin-mediated signaling pathway" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098794" secondary="postsynapse" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007163" secondary="establishment or maintenance of cell polarity" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030027" secondary="lamellipodium" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030036" secondary="actin cytoskeleton organization" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090051" secondary="negative regulation of cell migration involved in sprouting angiogenesis" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-193634" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038027" secondary="apolipoprotein A-I-mediated signaling pathway" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000177" secondary="regulation of neural precursor cell proliferation" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8849471" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048812" secondary="neuron projection morphogenesis" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007266" secondary="Rho protein signal transduction" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030334" secondary="regulation of cell migration" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8980692" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001300891.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043200" secondary="response to amino acid" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903673" secondary="mitotic cleavage furrow formation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033144" secondary="negative regulation of intracellular steroid hormone receptor signaling pathway" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003100" secondary="regulation of systemic arterial blood pressure by endothelin" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9013106" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-4086400" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5627117" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045198" secondary="establishment of epithelial cell apical/basal polarity" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045665" secondary="negative regulation of neuron differentiation" version="SP_206"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL</sequence>
            </interactor>
            <interactor id="665223">
                <names>
                    <shortLabel>cdn1b_mouse</shortLabel>
                    <fullName>Cyclin-dependent kinase inhibitor 1B</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Cyclin-dependent kinase inhibitor p27</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p27Kip1</alias>
                    <alias typeAc="MI:0301" type="gene name">Cdkn1b</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P46414" version="SP_65" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007507" secondary="heart development" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000082" secondary="G1/S transition of mitotic cell cycle" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69202" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69563" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004860" secondary="protein kinase inhibitor activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031116" secondary="positive regulation of microtubule polymerization" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046686" secondary="response to cadmium ion" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000003115" version="SP_174" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051087" secondary="chaperone binding" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804116" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000003031" version="SP_174" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000145056" version="SP_174" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9634638" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043200" secondary="response to amino acid" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071407" secondary="cellular response to organic cyclic compound" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-198323" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045930" secondary="negative regulation of mitotic cell cycle" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045786" secondary="negative regulation of cell cycle" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8849470" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2559586" version="SP_174"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8BG74" version="SP_102" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009749" secondary="response to glucose" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904706" secondary="negative regulation of vascular associated smooth muscle cell proliferation" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_174"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-445N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050680" secondary="negative regulation of epithelial cell proliferation" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902746" secondary="regulation of lens fiber cell differentiation" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031464" secondary="Cul4A-RING E3 ubiquitin ligase complex" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060770" secondary="negative regulation of epithelial cell proliferation involved in prostate gland development" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904030" secondary="negative regulation of cyclin-dependent protein kinase activity" version="SP_174"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P46414" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045736" secondary="negative regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" secondary="regulation of cell cycle" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004861" secondary="cyclin-dependent protein serine/threonine kinase inhibitor activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007346" secondary="regulation of mitotic cell cycle" version="SP_174"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1005742" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000079" secondary="regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030544" secondary="Hsp70 protein binding" version="SP_174"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029843" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9607240" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007605" secondary="sensory perception of sound" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043434" secondary="response to peptide hormone" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045737" secondary="positive regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000003115" version="SP_174" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030332" secondary="cyclin binding" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-187577" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000204807" version="SP_174" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008219" secondary="cell death" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000065832" version="SP_174" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071285" secondary="cellular response to lithium ion" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010942" secondary="positive regulation of cell death" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042326" secondary="negative regulation of phosphorylation" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905179" secondary="negative regulation of cardiac muscle tissue regeneration" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051271" secondary="negative regulation of cellular component movement" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007096" secondary="regulation of exit from mitosis" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2559582" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006813" secondary="potassium ion transport" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048102" secondary="autophagic cell death" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048839" secondary="inner ear development" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071236" secondary="cellular response to antibiotic" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033673" secondary="negative regulation of kinase activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902806" secondary="regulation of cell cycle G1/S phase transition" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000067327" version="SP_174" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69656" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030308" secondary="negative regulation of cell growth" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007219" secondary="Notch signaling pathway" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001890" secondary="placenta development" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032355" secondary="response to estradiol" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_174"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003175" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69231" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045732" secondary="positive regulation of protein catabolic process" version="SP_174"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_034005.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019903" secondary="protein phosphatase binding" version="SP_174"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVNHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGRYEWQEVERGSLPEFYYRPPRPPKSACKVLAQESQDVSGSRQAVPLIGSQANSEDRHLVDQMPDSSDNPAGLAEQCPGMRKRPAAEDSSSQNKRANRTEENVSDGSPNAGTVEQTPKKPGLRRQT</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-11238-1" id="665224">
                <names>
                    <shortLabel>rhoa-cdkn1b</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-4981092" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-11238-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7467584" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>665221</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="665225">
                        <names>
                            <shortLabel>rhoa_mouse</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-4981093" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7467593" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>665222</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>monoclonal western</shortLabel>
                                    <fullName>monoclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">monoclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0072" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-955" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="665226">
                        <names>
                            <shortLabel>cdn1b_mouse</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">p27</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-4981117" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7467590" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>665223</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F6B</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
