IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ roguev-2001-1 The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast tap tandem affinity purification TAP TAP tap fingerprinting peptide massfingerprinting fingerprinting Roguev A., Schaft D., Shevchenko A., Pijnappel WW., Wilm M., Aasland R., Stewart AF. Chromatin - Epigenetic interactions resulting in chromatin modulation stewart@mpi-cbg.de EMBO J. (0261-4189) 2001 Only protein-protein interactions imex curation roguev-2001-2 The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast methyltransferase as methyltransferase assay methyltransferase as predetermined predetermined participant predetermined Roguev A., Schaft D., Shevchenko A., Pijnappel WW., Wilm M., Aasland R., Stewart AF. Chromatin - Epigenetic interactions resulting in chromatin modulation stewart@mpi-cbg.de EMBO J. (0261-4189) 2001 Only protein-protein interactions imex curation shg1_yeast COMPASS component SHG1 CPS15 YBR258C YBR1726 SHG1 Complex proteins associated with SET1 protein SHG1 Set1C component SHG1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MAYNQEDSKRLSDKYKKEGHFDKLKREILSNPWNNTEENSESFEQALRKRVASTVKEMVNEDEELIFKNRGLTSALIESQLVKDNYLKLGSKMEGDNGDGEKKFDLDVYVRSKLQDPKLLEMIKGQLQETLNSYEEEANGST set1_yeast Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 YTX1 KMT2 COMPASS component SET1 SET domain-containing protein 1 Lysine N-methyltransferase 2 YHR119W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSNYYRRAHASSGSYRQPQEQPQYSRSGHYQYSNGHSHQQYSSQYNQRRRYNHNDGTRRRYNDDRPHSSNNASTRQYYATNNSQSGPYVNKKSDISSRRGMSQSRYSNSNVHNTLASSSGSLPTESALLLQQRPPSVLRYNTDNLKSKFHYFDPIKGEFFNKDKMLSWKATDKEFSETGYYVVKELQDGQFKFKIKHRHPEIKASDPRNENGIMTSGKVATHRKCRNSLILLPRISYDRYSLGPPPSCEIVVYPAQDSTTTNIQDISIKNYFKKYGEISHFEAFNDPNSALPLHVYLIKYASSDGKINDAAKAAFSAVRKHESSGCFIMGFKFEVILNKHSILNNIISKFVEINVKKLQKLQENLKKAKEKEAENEKAKELQGKDITLPKEPKVDTLSHSSGSEKRIPYDLLGVVNNRPVLHVSKIFVAKHRFCVEDFKYKLRGYRCAKFIDHPTGIYIIFNDIAHAQTCSNAESGNLTIMSRSRRIPILIKFHLILPRFQNRTRFNKSSSSSNSTNVPIKYESKEEFIEATAKQILKDLEKTLHVDIKKRLIGPTVFDALDHANFPELLAKRELKEKEKRQQIASKIAEDELKRKEEAKRDFDLFGLYGGYAKSNKRNLKRHNSLALDHTSLKRKKLSNGIKPMAHLLNEETDSKETTPLNDEGITRVSKEHDEEDENMTSSSSEEEEEEAPDKKFKSESEPTTPESDHLHGIKPLVPDQNGSSDVLDASSMYKPTATEIPEPVYPPEEYDLKYSQTLSSMDLQNAIKDEEDMLILKQLLSTYTPTVTPETSAALEYKIWQSRRKVLEEEKASDWQIELNGTLFDSELQPGSSFKAEGFRKIADKLKINYLPHRRRVHQPLNTVNIHNERNEYTPELCQREESSNKEPSDSVPQEVSSSRDNRASNRRFQQDIEAQKAAIGTESELLSLNQLNKRKKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN B7FA5D60F71063FD swd3_yeast COMPASS component SWD3 CPS30 YBR175W YBR1237 SWD3 SAF35 Complex proteins associated with SET1 protein SWD3 Set1C component SWD3 protein protein yeast Saccharomyces cerevisiae Baker's yeast MFQFVTPVGTQNGLKATCAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLYHHSSPVMSIHCFGNIMCSLALNGDCCLWRWV E8E88C483D1CD776 bre2_yeast COMPASS component BRE2 Complex proteins associated with SET1 protein BRE2 Set1C component BRE2 Brefeldin-A sensitivity protein 2 CPS60 YLR015W BRE2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MKLGIIPYQEGTDIVYKNALQGQQEGKRPNLPQMEATHQIKSSVQGTSYEFVRTEDIPLNRRHFVYRPCSANPFFTILGYGCTEYPFDHSGMSVMDRSEGLSISRDGNDLVSVPDQYGWRTARSDVCIKEGMTYWEVEVIRGGNKKFADGVNNKENADDSVDEVQSGIYEKMHKQVNDTPHLRFGVCRREASLEAPVGFDVYGYGIRDISLESIHEGKLNCVLENGSPLKEGDKIGFLLSLPSIHTQIKQAKEFTKRRIFALNSHMDTMNEPWREDAENGPSRKKLKQETTNKEFQRALLEDIEYNDVVRDQIAIRYKNQLFFEATDYVKTTKPEYYSSDKRERQDYYQLEDSYLAIFQNGKYLGKAFENLKPLLPPFSELQYNEKFYLGYWQHGEARDESNDKNTTSAKKKKQQQKKKKGLILRNKYVNNNKLGYYPTISCFNGGTARIISEEDKLEYLDQIRSAYCVDGNSKVNTLDTLYKEQIAEDIVWDIIDELEQIALQQ D5B33221E9F10379 swd1_yeast COMPASS component SWD1 CPS50 YAR003W FUN16 SWD1 SAF49 Complex proteins associated with SET1 protein SWD1 Set1C component SWD1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MNILLQDPFAVLKEHPEKLTHTIENPLRTECLQFSPCGDYLALGCANGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDGRLLLTSSRDWSIKLWDLSKPSKPLKEIRFDSPIWGCQWLDAKRRLCVATIFEESDAYVIDFSNDPVASLLSKSDEKQLSSTPDHGYVLVCTVHTKHPNIIIVGTSKGWLDFYKFHSLYQTECIHSLKITSSNIKHLIVSQNGERLAINCSDRTIRQYEISIDDENSAVELTLEHKYQDVINKLQWNCILFSNNTAEYLVASTHGSSAHELYIWETTSGTLVRVLEGAEEELIDINWDFYSMSIVSNGFESGNVYVWSVVIPPKWSALAPDFEEVEENVDYLEKEDEFDEVDEAEQQQGLEQEEEIAIDLRTREQYDVRGNNLLVERFTIPTDYTRIIKMQSS 90C389612AB66231 swd2_yeast COMPASS component SWD2 CPS35 YKL018W SWD2 SAF37 Complex proteins associated with SET1 protein SWD2 Set1C component SWD2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLTSSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLETNQYLRYFSGHGALVNDLKMNPVNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIAYDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLVGSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAIWNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADETVDFYVYDE 5453C193A5C0AEEC sdc1_yeast COMPASS component SDC1 SDC1 SAF19 CPS25 YDR469W Complex proteins associated with SET1 protein SDC1 Set1C component SDC1 Suppressor of CDC25 protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MNESENSPQHNEVTVPMVEDTSSNADIPMEQIQREDNKNYDKHDNECFDMNGNHNNNSDNLQFDSVPSSATKDLKNIKSVTNQNVKIEESSSTNSVIEESSEPKISKLENVNLAATVGGSQTRKYLNTNVTPHLLAGMRLIAVQQPEDPLRVLGEYLIEQSNILKSGEKESNASK B40247D641124306 spp1_yeast COMPASS component SPP1 SPP1 SAF41 Complex proteins associated with SET1 protein SPP1 Set1C component SPP1 Suppressor of PRP protein 1 CPS40 YPL138C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSLPQWCPPHSTLKRNPTTGEDVYCICKRPDYGELMVGCDGCDDWFHFTCLHIPEQFKDLVFSFYCPYCQAGITGKNKDAIINGEGSLPKTLWKRKCRISDCYKPCLQDSKYCSEEHGREFVNDIWSRLKTDEDRAVVKKMVEQTGHIDKFKKFGQLDFIDNNIVVKTDDEKEIFDQIVVRDMTLKTLEDDLQEVQEISLPLFKKKLELLEVYLGWLDNVYTEMRKLDDDAASHVECGKEDSKGTKRKKKKNSSRSRARKNICGYCSTYERIPCSVEEFVRDFGSNEEATKIHEVCTKWKCNRHLDWVSTNQEQYLQQIDSLESMQERLQHLIQARKKQLNIQYYEEILRRGL F4B8DFE0CB358CA4 ref2_yeast RNA end formation protein 2 YD9346.06 YDR195W REF2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSAPVPQLVNISHALQASTIQQIRLDMVDFNKDCKLSSIQLARIDKYIDSLQAALNQFTKDNLHIERKEKNVTEADIQLYSGLKSMYLDYLNQLIKLKHEKQHHSTPPIANDVSLDFFVNQLPKFSPEERKNYIDNLILNKNSHNRLSKMDGLVDAVINLCVLDTSVAENVRSYMKLLDTLGFQKGSNSTGTKANLKKKLASSKAKIKDSEKEKEKEKDKSKVKMKTKLKPSPLLNNDDKNSSPSPTASTSSMKKLKSGLFNKNEAKSTESLPTSSKKKLSFSKYLNKDDADMTKLGTKRSIDVDFKVNPEASTVASNIISSSTSGSSTTTVATPASSEEPLKKKTKISVQDSNVQSILRNGKPKKARISSIKFLDDSQLIKVYGDDLPNQGLQVSPTQLKKILKPFKEGEPKEIILFEDMSIKLKPLDLMFLKNTNSDDYMDISETKGGPIHCETRTPLIYRKNFNHFNPDLNKRPPREPIEFDLNGNTNSTPTIAKAFGKNSLLLRKDRGGLPYKHVPIVKRNKYPPRPVH 36B0982B005697C4 ysh1_yeast Endoribonuclease YSH1 YSH1 BRR5 Yeast 73 kDa homolog 1 YLR277C mRNA 3'-end-processing protein YSH1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHEPRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSVMLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIKEENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHDHNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGKSTAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC 901582F0C33AD6F7 pta1_yeast Pre-tRNA-processing protein PTA1 PTA1 FUN39 YAL043C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSSAEMEQLLQAKTLAMHNNPTEMLPKVLETTASMYHNGNLSKLKLPLAKFFTQLVLDVVSMDSPIANTERPFIAAQYLPLLLAMAQSTADVLVYKNIVLIMCASYPLVLDLVAKTSNQEMFDQLCMLKKFVLSHWRTAYPLRATVDDETDVEQWLAQIDQNIGVKLATIKFISEVVLSQTKSPSGNEINSSTIPDNHPVLNKPALESEAKRLLDMLLNYLIEEQYMVSSVFIGIINSLSFVIKRRPQTTIRILSGLLRFNVDAKFPLEGKSDLNYKLSKRFVERAYKNFVQFGLKNQIITKSLSSGSGSSIYSKLTKISQTLHVIGEETKSKGILNFDPSKGNSKKTLSRQDKLKYISLWKRQLSALLSTLGVSTKTPTPVSAPATGSSTENMLDQLKILQKYTLNKASHQGNTFFNNSPKPISNTYSSVYSLMNSSNSNQDVTQLPNDILIKLSTEAILQMDSTKLITGLSIVASRYTDLMNTYINSVPSSSSSKRKSDDDDDGNDNEEVGNDGPTANSKKIKMETEPLAEEPEEPEDDDRMQKMLQEEESAQEISGDANKSTSAIKEIAPPFEPDSLTQDEKLKYLSKLTKKLFELSGRQDTTRAKSSSSSSILLDDDDSSSWLHVLIRLVTRGIEAQEASDLIREELLGFFIQDFEQRVSLIIEWLNEEWFFQTSLHQDPSNYKKWSLRVLESLGPFLENKHRRFFIRLMSELPSLQSDHLEALKPICLDPARSSLGFQTLKFLIMFRPPVQDTVRDLLHQLKQEDEGLHKQCDSLLDRLK E2AB1F468B7BC8D0 mpe1_yeast Protein MPE1 YKL316 YKL059C MPE1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGTDFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNATRYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFFKSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFEGKRIRRTTGIPKKFLKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENRQIDGDETIWRKGHFKDLPDDLKCPLTGGLLRQPVKTSKCCNIDFSKEALENALVESDFVCPNCETRDILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSLPTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK 487567F6FD2C3F61 cft1_yeast Protein CFT1 CFT1 Cleavage factor two protein 1 YHH1 YDR301W protein protein yeast Saccharomyces cerevisiae Baker's yeast MNVYDDVLDATVVSHSLATHFTTSDYEELLVVRTNILSVYRPTRDGKLYLTDEFKFHGLITDIGLIPQKDSPLSCLLLCTGVAKISILKFNTLTNSIDTLSLHYYEGKFKGKSLVELAKISTLRMDPGSSCALLFNNDIIAFLPFHVNKNDDDEEEEDEDENIDDSELIHSMNQKSQGTNTFNKRKRTKLGDKFTAPSVVLVASELYEGAKNIIDIQFLKNFTKPTIALLYQPKLVWAGNTTISKLPTQYVILTLNIQPAESATKIESTTIAFVKELPWDLHTIVPVSNGAIIVGTNELAFLDNTGVLQSTVLLNSFADKELQKTKIINNSSLEIMFREKNTTSIWIPSSKSKNGGSNNDETLLLMDLKSNIYYIQMEAEGRLLIKFDIFKLPIVNDLLKENSNPKCITRLNATNSNKNMDLFIGFGSGNALVLRLNNLKSTIETREAHNPSSGTNSLMDINDDDDEEMDDLYADEAPENGLTTNDSKGTVETVQPFDIELLSSLRNVGPITSLTVGKVSSIDDVVKGLPNPNKNEYSLVATSGNGSGSHLTVIQTSVQPEIELALKFISITQIWNLKIKGRDRYLITTDSTKSRSDIYESDNNFKLHKGGRLRRDATTVYISMFGEEKRIIQVTTNHLYLYDTHFRRLTTIKFDYEVIHVSVMDPYILVTVSRGDIKIFELEEKNKRKLLKVDLPEILNEMVITSGLILKSNMCNEFLIGLSKSQEEQLLFTFVTADNQIIFFTKDHNDRIFQLNGVDQLNESLYISTYQLGDEIVPDPSIKQVMINKLGHDNKEEYLTILTFGGEIYQYRKLPQRRSRFYRNVTRNDLAITGAPDNAYAKGVSSIERIMHYFPDYNGYSVIFVTGSVPYILIKEDDSTPKIFKFGNIPLVSVTPWSERSVMCVDDIKNARVYTLTTDNMYYGNKLPLKQIKISNVLDDYKTLQKLVYHERAQLFLVSYCKRVPYEALGEDGEKVIGYDENVPHAEGFQSGILLINPKSWKVIDKIDFPKNSVVNEMRSSMIQINSKTKRKREYIIAGVANATTEDTPPTGAFHIYDVIEVVPEPGKPDTNYKLKEIFQEEVSGTVSTVCEVSGRFMISQSQKVLVRDIQEDNSVIPVAFLDIPVFVTDSKSFGNLLIIGDAMQGFQFIGFDAEPYRMISLGRSMSKFQTMSLEFLVNGGDMYFAATDADRNVHVLKYAPDEPNSLSGQRLVHCSSFTLHSTNSCMMLLPRNEEFGSPQVPSFQNVGGQVDGSVFKIVPLSEEKYRRLYVIQQQIIDRELQLGGLNPRMERLANDFYQMGHSMRPMLDFNVIRRFCGLAIDRRKSIAQKAGRHAHFEAWRDIINIEFSMRSLCQGK BC50D3770E9E758E pp12_yeast Serine/threonine-protein phosphatase PP1-2 GLC7 CID1 DIS2 YER133W protein protein yeast Saccharomyces cerevisiae Baker's yeast MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSLPRQAGGRKKK 71B20E3A4ED93235 ady1_yeast Prospore formation at selected spindle poles protein 1 Accumulates dyads protein 1 PFS1 ADY1 YHR185C protein protein yeast Saccharomyces cerevisiae Baker's yeast MNQGYTQLSAPELKETKTSKLNKMNNFRSSPIAEIINKIPPDCGKIQNTTFPEFNPALRRRQHEQWPAYEKPIRVTDSMSPQLSSINCLPNLYPHGTLPLPNPYLSYLNHIEKVNCQDVKFSNWSVLHNSNNGFEIPTYFSPRTTQNMPCSEKVESWLERLPIFVGFDGYLFTNCFDYEYMLDWEETEFTFEKTSCMETDYSKALTDTDIIYIQEKKIEALIRNQYLKEYEFSQKDF syc1_yeast Protein SYC1 YOR179C SYC1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDLPKDKSDRTHQRINLNNSGTDRTNDLYLHIVQTFGCIETTATENATKLLMLGDVEVEISASSVSIEWTQKSMISQTIADSIVIMIIGLCASDKNVLSESELKERNHNVWKIQELQNLFREQFGDSFSIDEGIGKKENVKNGSVTIGKSKATIDFSTMKLIDCNSNPLKGRVESILSIGQKLTTPLC 6FB2B030A983065D h3_yeast Histone H3 SIN2 YNL031C N2749 HHT1 YBR010W YBR0201 HHT2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS A6115FEB480AC67A set1-bre2-1 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654914 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654915 unspecified role unspecified role bait bait c-terminal tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false Stoichiometry: 2.0 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654918 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654919 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654921 unspecified role unspecified role prey prey Stoichiometry: 2.0 association association false false false Figure 1 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations. set1-bre2-2 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654915 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654918 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654914 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654917 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 2.0 N/A 654921 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654919 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 association association false false false Figure 2 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations . set1-bre2-3 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654914 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654919 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654921 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654915 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654918 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 1.0 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 association association false false false Figure 2 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations . set1-bre2-4 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654921 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 2.0 N/A 654914 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654915 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654919 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654918 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 association association false false false Figure 2 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations . set1-bre2-5 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654922 unspecified role unspecified role prey prey N/A 654923 unspecified role unspecified role prey prey N/A 654924 unspecified role unspecified role prey prey N/A 654925 unspecified role unspecified role prey prey N/A 654926 unspecified role unspecified role prey prey N/A 654917 unspecified role unspecified role prey prey N/A 654919 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 654915 unspecified role unspecified role prey prey N/A 654921 unspecified role unspecified role prey prey N/A 654927 unspecified role unspecified role prey prey N/A 654928 unspecified role unspecified role prey prey N/A 654929 unspecified role unspecified role prey prey association association false false false Figure 2 set1-bre2-6 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654915 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654918 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654916 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 1.0 N/A 654919 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654914 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654921 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 association association false false false Figure 2 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations . set1-bre2-7 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654920 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 1.0 N/A 654918 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654914 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654921 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654915 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 association association false false false Figure 2 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations . set1-bre2-8 Components of the Compass/Set1 complex identified by TAP 654912 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654921 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654918 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654919 unspecified role unspecified role prey prey Stoichiometry: 1.0 N/A 654914 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 1.0 N/A 654915 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 association association false false false Figure 2 Stoichiometry estimated from Coomassie staining intensities from each of the affinity purified preparations . sdc1-bre2-1 Interaction between Bre2 and Sdc1 determined by TAP 654912 N/A 654917 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 2.0 N/A 654920 unspecified role unspecified role prey prey Stoichiometry: 1.0 physical association physical association false false false Figure 4 Interaction observed in cells lacking Set1. sdc1-bre2-2 Interaction between Bre2 and Sdc1 determined by TAP 654912 N/A 654917 unspecified role unspecified role prey prey Stoichiometry: 2.0 N/A 654920 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 1.0 physical association physical association false false false Figure 4 Interaction detected in cells lacking Set1. swd1-swd3-1 Interaction between Swd1 and Swd3 determined by TAP 654912 N/A 654918 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Stoichiometry: 1.0 N/A 654916 unspecified role unspecified role prey prey Stoichiometry: 1.0 physical association physical association false false false Figure 4 Interaction observed in cells lacking Set1 set1-h3-1 Set1 shows methyltransferase activity towards Histone N3 654913 N/A 654915 enzyme enzyme unspecified role unspecified role N/A 654930 enzyme target enzyme target substrate substrate unspecified role unspecified role region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false methylation methylation reaction methylation false false false Methylation of Lys-5 of histone H3