IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ mingorance-1997-1 Recombinant rat liver S-adenosyl-L-methionine synthetase tetramers and dimers are in equilibrium. in vitro In vitro reverse phase chrom reverse phase chromatography reverse phase chrom predetermined predetermined participant predetermined Mingorance J., Alvarez L., Pajares MA., Mato JM. Separated on phenyl-sepharose. Participants identified by molecular weight confirmed by enzymic activity. Int. J. Biochem. Cell Biol. (1357-2725) 1997 Only protein-protein interactions imex curation metk1_rat S-adenosylmethionine synthase isoform type-1 Mat1a Ams1 Methionine adenosyltransferase 1 Methionine adenosyltransferase I/III protein protein rat Rattus norvegicus (Rat) Rat MNGPVDGLCDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMIDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRMADLRRSGVLPWLRPDSKTQVTVQYVQDNGAVIPVRVHTIVISVQHNEDITLEAMREALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSKKTERDELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF metk1-metk1-1 Homodimerization of Mat1a identified by hydrophobic interaction chromatography 492902 N/A 492903 unspecified role unspecified role neutral component neutral component ecobb Escherichia coli (strain B / BL21) Stoichiometry: 2.0 physical association physical association false false false Figs. 1 and 2. metk1-metk1-2 Homotetramerization of Mat1a identified by hydrophobic interaction chromatography 492902 N/A 492903 unspecified role unspecified role neutral component neutral component ecobb Escherichia coli (strain B / BL21) Stoichiometry: 4.0 physical association physical association false false false Fig. 1.