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                    <shortLabel>evdonin-2006-1</shortLabel>
                    <fullName>Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells.</fullName>
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                            <shortLabel>human-a_431</shortLabel>
                            <fullName>Homo sapiens epidermoid carcinoma</fullName>
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                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
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                        <shortLabel>predetermined</shortLabel>
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                    <attribute name="author-list" nameAc="MI:0636">Evdonin AL., Guzhova IV., Margulis BA., Medvedeva ND.</attribute>
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                    <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2006</attribute>
                    <attribute name="imex-exported">2009-01-08</attribute>
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                    </names>
                </organism>
                <sequence>MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS</sequence>
            </interactor>
            <interactor id="574364">
                <names>
                    <shortLabel>egfr_human</shortLabel>
                    <fullName>Epidermal growth factor receptor</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">ERBB1</alias>
                    <alias typeAc="MI:0301" type="gene name">EGFR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Receptor tyrosine-protein kinase erbB-1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Proto-oncogene c-ErbB-1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ERBB</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HER1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P00533" version="SP_130" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JZ0" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033590" secondary="response to cobalamin" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MOX" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4RJ4" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JX4" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GT8" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JQ7" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3POZ" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051205" secondary="protein insertion into membrane" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GTY" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5SX4" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UGA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Z4D" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043006" secondary="activation of phospholipase A2 activity by calcium-mediated signaling" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J5F" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LZB" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-182971" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007173" secondary="epidermal growth factor receptor signaling pathway" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1IVO" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XWD" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071549" secondary="cellular response to dexamethasone stimulus" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JWL" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005006" secondary="epidermal growth factor-activated receptor activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5X26" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1DNQ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2EXQ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TFW" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WXN" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903800" secondary="positive regulation of production of miRNAs involved in gene silencing by miRNA" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031901" secondary="early endosome membrane" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050730" secondary="regulation of peptidyl-tyrosine phosphorylation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LUB" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ITT" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060252" secondary="positive regulation of glial cell proliferation" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-179812" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TG1" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UV7" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005925" secondary="focal adhesion" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XDL" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZJV" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_958441.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XGN" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043586" secondary="tongue development" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1963640" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007169" secondary="transmembrane receptor protein tyrosine kinase signaling pathway" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3VRP" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J9Z" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CAP" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043406" secondary="positive regulation of MAP kinase activity" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042177" secondary="negative regulation of protein catabolic process" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097708" secondary="intracellular vesicle" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048408" secondary="epidermal growth factor binding" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HCZ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CAQ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5X27" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3G5Y" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005178" secondary="integrin binding" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033594" secondary="response to hydroxyisoflavone" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013507" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LQM" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DUK" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000275493" version="SP_279" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5SX5" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1M14" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J5E" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WRG" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902722" secondary="positive regulation of prolactin secretion" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2EB3" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RF9" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3W2R" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3W33" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006412" secondary="translation" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8857538" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2GS7" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ITN" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032930" secondary="positive regulation of superoxide anion generation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C8K" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046777" secondary="protein autophosphorylation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LV6" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006212" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CZI" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2EXP" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3W2S" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GOP" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AEI" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9609690" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CAV" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6P8Q" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070257" secondary="positive regulation of mucus secretion" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3OP0" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I24" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TG0" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000420316"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HCY" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PFV" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2GS2" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZSE" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V66" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LRM" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5638303" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000342376"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071276" secondary="cellular response to cadmium ion" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I20" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EDQ" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CNN" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5X28" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ARU" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097421" secondary="liver regeneration" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033138" secondary="positive regulation of peptidyl-serine phosphorylation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3W2Q" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3W32" version="SP_279"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-297353" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6S9B" version="SP_279"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000494" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" secondary="double-stranded DNA binding" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010008" secondary="endosome membrane" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000275493"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007202" secondary="activation of phospholipase C activity" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018108" secondary="peptidyl-tyrosine phosphorylation" version="SP_279"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-405N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000275493" version="SP_279" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HCX" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004713" secondary="protein tyrosine kinase activity" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005219.2"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2M0B" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LUD" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001942" secondary="hair follicle development" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4RJ6" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FED" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030307" secondary="positive regulation of cell growth" version="SP_279"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14225" version="SP_130" refType="secondary-ac" refTypeAc="MI:0360"/>
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                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000342916"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6S9C" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CNO" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UG9" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042060" secondary="wound healing" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CAS" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1250196" version="SP_279"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-28985169" refType="intact-secondary"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5637810" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3VJO" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001618" secondary="virus receptor activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JIV" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048812" secondary="neuron projection morphogenesis" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J9Y" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6B3S" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FEE" version="SP_279"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UMD8" version="SP_130" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O00732" version="SP_130" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HG5" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EDR" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003682" secondary="chromatin binding" version="SP_279"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q68GS5" version="SP_142" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009925" secondary="basal plasma membrane" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J6M" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TFZ" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045907" secondary="positive regulation of vasoconstriction" version="SP_279"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010750" secondary="positive regulation of nitric oxide mediated signal transduction" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UG2" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3G5V" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GMP" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KRO" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1236382" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007623" secondary="circadian rhythm" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045739" secondary="positive regulation of DNA repair" version="SP_279"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA</sequence>
            </interactor>
            <interactor id="574365">
                <names>
                    <shortLabel>myd88_human</shortLabel>
                    <fullName>Myeloid differentiation primary response protein MyD88</fullName>
                    <alias typeAc="MI:0301" type="gene name">MYD88</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q99836" version="SP_68" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000157" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050671" secondary="positive regulation of lymphocyte proliferation" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DOM" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042742" secondary="defense response to bacterium" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007254" secondary="JNK cascade" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z5V" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016064" secondary="immunoglobulin mediated immune response" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5602680" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="J3KPU4" version="SP_142" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3134963" version="SP_209"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001166037.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BEQ" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DQ60" version="SP_122" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JS7" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1810476" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050830" secondary="defense response to Gram-positive bacterium" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000341" secondary="regulation of chemokine (C-X-C motif) ligand 2 production" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" secondary="cellular response to mechanical stimulus" version="SP_209"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000396334" version="SP_209" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" secondary="positive regulation of chemokine production" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" secondary="positive regulation of tumor necrosis factor production" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DQ72" version="SP_122" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53XS7" version="SP_84" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010008" secondary="endosome membrane" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070498" secondary="interleukin-1-mediated signaling pathway" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032740" secondary="positive regulation of interleukin-17 production" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070935" secondary="3'-UTR-mediated mRNA stabilization" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="J3KQJ6" version="SP_142" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9020702" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902622" secondary="regulation of neutrophil migration" version="SP_209"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000488" version="SP_209"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000379625" version="SP_209" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002459.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002283" secondary="neutrophil activation involved in immune response" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032747" secondary="positive regulation of interleukin-23 production" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034158" secondary="toll-like receptor 8 signaling pathway" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166058" version="SP_209"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001166039.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005121" secondary="Toll binding" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5602498" version="SP_209"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035897" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900227" secondary="positive regulation of NLRP3 inflammasome complex assembly" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-209543" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070944" secondary="neutrophil-mediated killing of bacterium" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BER" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1257604" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="J3KQ87" version="SP_142" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975871" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" secondary="positive regulation of interleukin-8 production" version="SP_209"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000498360" version="SP_209" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005149" secondary="interleukin-1 receptor binding" version="SP_209"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000172936" version="SP_209" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_209"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q99836" version="SP_209"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_209"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001166040.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034249" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EO7" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7L6W" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032494" secondary="response to peptidoglycan" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6I3N" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048661" secondary="positive regulation of smooth muscle cell proliferation" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006909" secondary="phagocytosis" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014069" secondary="postsynaptic density" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1236974" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900017" secondary="positive regulation of cytokine production involved in inflammatory response" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P78397" version="SP_68" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000650905" version="SP_209" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005123" secondary="death receptor binding" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DKH8" version="SP_98" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140052" secondary="cellular response to oxidised low-density lipoprotein particle stimulus" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042832" secondary="defense response to protozoan" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002755" secondary="MyD88-dependent toll-like receptor signaling pathway" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043621" secondary="protein self-association" version="SP_209"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MOP" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070976" secondary="TIR domain binding" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" secondary="defense response to virus" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060337" secondary="type I interferon signaling pathway" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975110" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009682" secondary="induced systemic resistance" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032481" secondary="positive regulation of type I interferon production" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090557" secondary="establishment of endothelial intestinal barrier" version="SP_209"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DKU4" version="SP_142" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002238" secondary="response to molecule of fungal origin" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031663" secondary="lipopolysaccharide-mediated signaling pathway" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008063" secondary="Toll signaling pathway" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007166" secondary="cell surface receptor signaling pathway" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070555" secondary="response to interleukin-1" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002269" secondary="leukocyte activation involved in inflammatory response" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975155" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975138" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035325" secondary="Toll-like receptor binding" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000338" secondary="regulation of chemokine (C-X-C motif) ligand 1 production" version="SP_209"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017281" version="SP_209"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" secondary="regulation of inflammatory response" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5603041" version="SP_209"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-31349N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_209"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5603037" version="SP_209"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-447677" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP</sequence>
            </interactor>
            <interactor id="574366">
                <names>
                    <shortLabel>tlr4_human</shortLabel>
                    <fullName>Toll-like receptor 4</fullName>
                    <alias typeAc="MI:0301" type="gene name">TLR4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">hToll</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O00206" version="SP_70" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" secondary="cellular response to mechanical stimulus" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" secondary="positive regulation of tumor necrosis factor production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UL8" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" secondary="positive regulation of interleukin-8 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002537" secondary="nitric oxide production involved in inflammatory response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043032" secondary="positive regulation of macrophage activation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010008" secondary="endosome membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z62" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032700" secondary="negative regulation of interleukin-17 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070430" secondary="positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032675" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030890" secondary="positive regulation of B cell proliferation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043406" secondary="positive regulation of MAP kinase activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060907" secondary="positive regulation of macrophage cytokine production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001875" secondary="lipopolysaccharide immune receptor activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032689" secondary="negative regulation of interferon-gamma production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" secondary="immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032707" secondary="negative regulation of interleukin-23 production" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166058" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120163" secondary="negative regulation of cold-induced thermogenesis" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003257.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042742" secondary="defense response to bacterium" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UM57" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5VZI9" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050135" secondary="NAD(P)+ nucleosidase activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" secondary="protein heterodimerization activity" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NAM" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-937041" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ULA" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A9XLQ0" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061809" secondary="NAD+ nucleotidase, cyclic ADP-ribose generating" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000157" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" secondary="early endosome" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" secondary="activation of innate immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014002" secondary="astrocyte development" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4G8A" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FXI" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975163" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D1CS53" version="SP_133" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042116" secondary="macrophage activation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002322" secondary="B cell proliferation involved in immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032727" secondary="positive regulation of interferon-alpha production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001726" secondary="ruffle" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032715" secondary="negative regulation of interleukin-6 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903223" secondary="positive regulation of oxidative stress-induced neuron death" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903428" secondary="positive regulation of reactive oxygen species biosynthetic process" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z65" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K1Y8" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166016" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032728" secondary="positive regulation of interferon-beta production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045671" secondary="negative regulation of osteoclast differentiation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" secondary="amyloid-beta binding" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045429" secondary="positive regulation of nitric oxide biosynthetic process" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032733" secondary="positive regulation of interleukin-10 production" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_612564.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050729" secondary="positive regulation of inflammatory response" version="SP_218"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5602498" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904466" secondary="positive regulation of matrix metallopeptidase secretion" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001530" secondary="lipopolysaccharide binding" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903974" secondary="positive regulation of cellular response to macrophage colony-stimulating factor stimulus" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5686938" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002224" secondary="toll-like receptor signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900227" secondary="positive regulation of NLRP3 inflammasome complex assembly" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900017" secondary="positive regulation of cytokine production involved in inflammatory response" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1236974" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002755" secondary="MyD88-dependent toll-like receptor signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071223" secondary="cellular response to lipoteichoic acid" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000343" secondary="positive regulation of chemokine (C-X-C motif) ligand 2 production" version="SP_218"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="O00206" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003591" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2562578" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031226" secondary="intrinsic component of plasma membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070434" secondary="positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140052" secondary="cellular response to oxidised low-density lipoprotein particle stimulus" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UL7" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007252" secondary="I-kappaB phosphorylation" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001611" version="SP_218"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-528701" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-140534" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" secondary="cellular response to interferon-gamma" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032497" secondary="detection of lipopolysaccharide" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" secondary="external side of plasma membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z63" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A9XLQ1" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070373" secondary="negative regulation of ERK1 and ERK2 cascade" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" secondary="response to lipopolysaccharide" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UK78" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5VZI8" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UL9" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051770" secondary="positive regulation of nitric-oxide synthase biosynthetic process" version="SP_218"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017241" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035666" secondary="TRIF-dependent toll-like receptor signaling pathway" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E194" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002730" secondary="regulation of dendritic cell cytokine production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032735" secondary="positive regulation of interleukin-12 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046696" secondary="lipopolysaccharide receptor complex" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006909" secondary="phagocytosis" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NAO" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z66" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_612567.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" secondary="positive regulation of chemokine production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060729" secondary="intestinal epithelial structure maintenance" version="SP_218"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-34769N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001891" secondary="phagocytic cup" version="SP_218"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9707616" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5603041" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042088" secondary="T-helper 1 type immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D1CS52" version="SP_134" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000483" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045348" secondary="positive regulation of MHC class II biosynthetic process" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000136869" version="SP_218" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000363089" version="SP_218" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000355622" version="SP_218" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031663" secondary="lipopolysaccharide-mediated signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010572" secondary="positive regulation of platelet activation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034142" secondary="toll-like receptor 4 signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016046" secondary="detection of fungus" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032720" secondary="negative regulation of tumor necrosis factor production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032732" secondary="positive regulation of interleukin-1 production" version="SP_218"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-10912-1" id="574367">
                <names>
                    <shortLabel>tlr2-egfr</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981822" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127435" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-10912-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>574362</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="574368">
                        <names>
                            <shortLabel>tlr2_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981823" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127458" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574363</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="574369">
                        <names>
                            <shortLabel>egfr_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981824" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127451" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574364</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F4A</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-10912-2" id="574370">
                <names>
                    <shortLabel>tlr2-myd88-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981836" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-10912-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127473" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>574362</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="574371">
                        <names>
                            <shortLabel>myd88_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981840" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127482" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574365</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="574372">
                        <names>
                            <shortLabel>tlr2_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981837" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127480" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574363</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F4A</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-10912-3" id="574373">
                <names>
                    <shortLabel>tlr4-myd88-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981845" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-10912-3" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127500" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>574362</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="574374">
                        <names>
                            <shortLabel>myd88_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981846" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127509" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574365</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="574375">
                        <names>
                            <shortLabel>tlr4_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981849" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127507" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574366</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F4B</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-10912-4" id="574376">
                <names>
                    <shortLabel>tlr4-egfr</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981896" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127511" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-10912-4" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>574362</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="574377">
                        <names>
                            <shortLabel>tlr4_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981897" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127520" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574366</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="574378">
                        <names>
                            <shortLabel>egfr_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-3981900" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7127518" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>574364</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F4B</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
