<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="493173">
                <names>
                    <shortLabel>zhang-2006k-1</shortLabel>
                    <fullName>Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="16362041" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-2738777" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="16362041" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-11483" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7949589" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/sj.emboj.7600913" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5218126" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-raw264_7</shortLabel>
                            <fullName>Mus musculus monocyte macrophage cell line RAW264</fullName>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>raw264_7</shortLabel>
                                <fullName>Mouse monocyte macrophage cellline RAW264.7</fullName>
                            </names>
                            <xref>
                                <primaryRef db="cabri" dbAc="MI:0246" id="ICLC ATL02001" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-2516175" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0321" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="cabri" dbAc="MI:0246" id="ECACC 91062702" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-959866" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Zhang D., Facchinetti V., Wang X., Huang Q., Qin J., Su B.</attribute>
                    <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2006</attribute>
                    <attribute name="imex-exported">2009-01-08</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="493174">
                <names>
                    <shortLabel>m3k3_mouse</shortLabel>
                    <fullName>Mitogen-activated protein kinase kinase kinase 3</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">MAPK/ERK kinase kinase 3</alias>
                    <alias typeAc="MI:0301" type="gene name">Map3k3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Mekk3</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q61084" version="SP_64" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090050" secondary="positive regulation of cell migration involved in sprouting angiogenesis" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001568" secondary="blood vessel development" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035556" secondary="intracellular signal transduction" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071864" secondary="positive regulation of cell proliferation in bone marrow" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_036077.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106311" secondary="protein threonine kinase activity" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106310" secondary="protein serine kinase activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000773" secondary="negative regulation of cellular senescence" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900745" secondary="positive regulation of p38MAPK cascade" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" secondary="protein kinase activity" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034879" version="SP_179"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q61084" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000270" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000020700" version="SP_179" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000002044" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004709" secondary="MAP kinase kinase kinase activity" version="SP_179"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-446250" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046777" secondary="protein autophosphorylation" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000002044" version="SP_179" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9020702" version="SP_179"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MDEQEALDSIMKDLVALQMSRRTRLSGYETMKNKDTGHPNRQSDVRIKFEHNGERRIIAFSRPVRYEDVEHKVTTVFGQPLDLHYMNNELSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHTSSSPHSGVSRQVRIKPSQSAGDINTIYQAPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSQMSRARSFPDNRKECSDRETQLYDKGVKGGTYPRRYHVSVHHKDYNDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGVAVQYLDPRGRLRSADSENALTVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLVY</sequence>
            </interactor>
            <interactor id="493175">
                <names>
                    <shortLabel>traf6_mouse</shortLabel>
                    <fullName>TNF receptor-associated factor 6</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">RING-type E3 ubiquitin transferase TRAF6</alias>
                    <alias typeAc="MI:0301" type="gene name">Traf6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">E3 ubiquitin-protein ligase TRAF6</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P70196" version="SP_76" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-937042" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002637" secondary="regulation of immunoglobulin production" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" secondary="in utero embryonic development" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5689880" version="SP_212"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_033450.2"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001290202.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043211" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000679" secondary="positive regulation of transcription regulatory region DNA binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070498" secondary="interleukin-1-mediated signaling pathway" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041310" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017907" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001841" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8BLV2" version="SP_76" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042826" secondary="histone deacetylase binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" secondary="immune response" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-975138" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-975871" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6811558" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035631" secondary="CD40 receptor complex" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016567" secondary="protein ubiquitination" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032735" secondary="positive regulation of interleukin-12 production" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037309" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-450302" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-937039" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031624" secondary="ubiquitin conjugating enzyme binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061630" secondary="ubiquitin protein ligase activity" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1257604" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5607764" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031435" secondary="mitogen-activated protein kinase kinase kinase binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6P9M0" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043011" secondary="myeloid dendritic cell differentiation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048468" secondary="cell development" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043422" secondary="protein kinase B binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" secondary="tumor necrosis factor-mediated signaling pathway" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030316" secondary="osteoclast differentiation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043507" secondary="positive regulation of JUN kinase activity" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-450321" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904996" secondary="positive regulation of leukocyte adhesion to vascular endothelial cell" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-166058" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071345" secondary="cellular response to cytokine stimulus" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032813" secondary="tumor necrosis factor receptor superfamily binding" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2871837" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005164" secondary="tumor necrosis factor receptor binding" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000027164" version="SP_212" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019221" secondary="cytokine-mediated signaling pathway" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004842" secondary="ubiquitin-protein transferase activity" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-202424" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043122" secondary="regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097400" secondary="interleukin-17-mediated signaling pathway" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5689896" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-937041" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000004949" version="SP_212" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-205043" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042475" secondary="odontogenesis of dentin-containing tooth" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051865" secondary="protein autoubiquitination" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-193692" version="SP_212"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P70196" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005811" secondary="lipid droplet" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048661" secondary="positive regulation of smooth muscle cell proliferation" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013083" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047485" secondary="protein N-terminus binding" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002083" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002726" secondary="positive regulation of T cell cytokine production" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012227" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-168638" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001293" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-445989" version="SP_212"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29812N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9020702" version="SP_212"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448028" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045453" secondary="bone resorption" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-937072" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009887" secondary="animal organ morphogenesis" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9645460" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-975144" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000209" secondary="protein polyubiquitination" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042981" secondary="regulation of apoptotic process" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046849" secondary="bone remodeling" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050852" secondary="T cell receptor signaling pathway" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000004949" version="SP_212" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045672" secondary="positive regulation of osteoclast differentiation" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-209543" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009898" secondary="cytoplasmic side of plasma membrane" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032743" secondary="positive regulation of interleukin-2 production" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042088" secondary="T-helper 1 type immune response" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001503" secondary="ossification" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" secondary="cellular response to DNA damage stimulus" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031996" secondary="thioesterase binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070534" secondary="protein K63-linked ubiquitination" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007249" secondary="I-kappaB kinase/NF-kappaB signaling" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031666" secondary="positive regulation of lipopolysaccharide-mediated signaling pathway" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070555" secondary="response to interleukin-1" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-975163" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001843" secondary="neural tube closure" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019886" secondary="antigen processing and presentation of exogenous peptide antigen via MHC class II" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008974" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-209560" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032147" secondary="activation of protein kinase activity" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042102" secondary="positive regulation of T cell proliferation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007250" secondary="activation of NF-kappaB-inducing kinase activity" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007254" secondary="JNK cascade" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" secondary="positive regulation of DNA-binding transcription factor activity" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027139" version="SP_212"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MSLLNCENSCGSSQSSSDCCAAMAASCSAAVKDDSVSGSASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEKEIHDQSCPLANIICEYCGTILIREQMPNHYDLDCPTAPIPCTFSVFGCHEKMQRNHLARHLQENTQLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQCNGIYIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEALIRQNHEEVMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQGTFIKDDTLLVRCEVSTRFDMGGLRKEGFQPRSTDAGV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-11483-1" id="493176">
                <names>
                    <shortLabel>traf6-map3k3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-2738771" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7949599" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-11483-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>493173</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="493177">
                        <names>
                            <shortLabel>m3k3_mouse</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-2738773" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7949610" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>493174</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="493178">
                        <names>
                            <shortLabel>traf6_mouse</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-2738772" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7949607" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>493175</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F5E</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
