UniProt UniProt http://www.uniprot.org shang-2003-2 Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. in vitro In vitro pull down pull down weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Shang C., Hazbun TR., Cheeseman IM., Aranda J., Fields S., Drubin DG., Barnes G. UniProtKB accession numbers could not be found for dad3 and dad4. Authors have shown interactions with these proteins in this study as well. Mol. Biol. Cell (1059-1524) 2003 IMEx Only protein-protein interactions imex curation imex curation shang-2003-1 Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Shang C., Hazbun TR., Cheeseman IM., Aranda J., Fields S., Drubin DG., Barnes G. Mol. Biol. Cell (1059-1524) 2003 IMEx Only protein-protein interactions imex curation imex curation shang-2003-4 Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Shang C., Hazbun TR., Cheeseman IM., Aranda J., Fields S., Drubin DG., Barnes G. Mol. Biol. Cell (1059-1524) 2003 IMEx Only protein-protein interactions imex curation imex curation shang-2003-3 Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. in vitro In vitro pull down pull down predetermined predetermined participant predetermined Shang C., Hazbun TR., Cheeseman IM., Aranda J., Fields S., Drubin DG., Barnes G. UniProtKB accession numbers have not been found for dad3 and dad4. Authors have shown interactions between these proteins in this study using this technique. Mol. Biol. Cell (1059-1524) 2003 IMEx Only protein-protein interactions imex curation imex curation dam1_yeast DASH complex subunit DAM1 YGR113W G6153 DAM1 Outer kinetochore protein DAM1 DUO1 and MPS1-interacting protein 1 Kinetochore assembly protein DAM1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSEDKAKLGTTRSATEYRLSIGSAPTSRRSSMGESSSLMKFADQEGLTSSVGEYNENTIQQLLLPKIRELSDSIITLDSNFTRLNFIHESLADLNESLGSLLYGIMSNSWCVEFSQAPHDIQDDLIAIKQLKSLEDEKNNLVMELSNMERGIKRKKDEQGENDLAKASQNKQFNQPLFPSSQVRKYRSYDNRDKRKPSKIGNNLQVENEEDYEDDTSSEASFVLNPTNIGMSKSSQGHVTKTTRLNNNTNSKLRRKSILHTIRNSIASGADLPIENDNVVNLGDLHPNNRISLGSGAARVVNGPVTKNRNSMFSGRAERKPTESRHSVAKKTEKKINTRPPFR F02DB6EE09BC2284 duo1_yeast DASH complex subunit DUO1 YGL061C DUO1 Outer kinetochore protein DUO1 Death upon overproduction protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSEQSQLDDSTIDKLIPQIFNEMRSNLNNTTNKFPKSTGGGASDNISANSNSIRSFNSITTQSLLKESESLDKITAMIKNVTAALKNNLPVYVNQVHEVCKSTNSILDSWINIHSQAGYIHKLMSDQTYLKLINDRLHNENVNTNDEDGSTLHNVIALKKKEILDLRQKLENRKGEKDAAPAKPPNQGLNPRYGVQSGRRPVPSAGISNNGRVRKTHVPASKRPSGIPRVTNRWTKPTASSSRKMFR 787F8AF869E3C978 spc34_yeast DASH complex subunit SPC34 YKR037C SPC34 34 kDa spindle pole component protein Outer kinetochore protein SPC34 protein protein yeast Saccharomyces cerevisiae Baker's yeast MGESLDRCIDDINRAVDSMSTLYFKPPGIFHNAILQGASNKASIRKDITRLIKDCNHDEAYLLFKVNPEKQSVSRRDGKEGVFDYVIKRDTDMKRNRRLGRPGEKPIIHVPKEVYLNKDRLDLNNKRRRTATTSGGGLNGFIFDTDLIGSSVISNSSSGTFKALSAVFKDDPQIQRLLYALENGSVLMEEESNNQRRKTIFVEDFPTDLILKVMAEVTDLWPLTEFKQDYDQLYHNYEQLSSKLRFIKKEVLLQDDRLKTMSQYHPSSSHDVAKIIRKEKDEIRRLEMEIANLQE C1061B49F6D4D308 ndc80_yeast Kinetochore protein NDC80 NDC80 80 kDa spindle component protein HEC1 Nuclear division cycle protein 80 TID3 Two-hybrid interaction with DMC1 protein 3 YIL144W protein protein yeast Saccharomyces cerevisiae Baker's yeast MQSSTSTDQHVLHHMDPHRFTSQIPTATSSQLRRRNSTNQGLTDMINKSIARNTISGTGIPTGGINKNKRTRSTVAGGTNGTALALNDKSNSRNSVSRLSINQLGSLQQHLSNRDPRPLRDKNFQSAIQEEIYDYLKKNKFDIETNHPISIKFLKQPTQKGFIIIFKWLYLRLDPGYGFTKSIENEIYQILKNLRYPFLESINKSQISAVGGSNWHKFLGMLHWMVRTNIKLDMCLNKVDRSLINQNTQEITILSQPLKTLDEQDQRQERYELMVEKLLIDYFTESYKSFLKLEDNYEPSMQELKLGFEKFVHIINTDIANLQTQNDNLYEKYQEVMKISQKIKTTREKWKALKSDSNKYENYVNAMKQKSQEWPGKLEKMKSECELKEEEIKALQSNISELHKILRKKGISTEQFELQNQEREKLTRELDKINIQSDKLTSSIKSRKLEAEGIFKSLLDTLRQYDSSIQNLTRSRSQLGHNVNDSSLKINISENLLDRDFHEGISYEQLFPKGSGINESIKKSILKLNDEIQERIKTIEKDNITLEKDIKNLKHDINEKTQINEKLELELSEANSKFELSKQENERLLVAQRIEIEKMEKKINDSNLLMKTKISDAEELVTSTELKLEELKVDLNRKRYKLHQQVIHVIDITSKFKINIQSSLENSENELGNVIEELRNLEFETEHNVTN 7DBC492227A80093 cenpp_yeast Inner kinetochore subunit CTF19 CTF19 YPL018W LPB13W MCM18 Chromosome transmission fidelity protein 19 Minichromosome maintenance protein 18 CENP-P homolog Constitutive centromere-associated network protein CTF19 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDFTSDTTNSHDTSNSHLSLEDAVGTHHAGEADVNIDGDEKQQLSLLDDDQVRALKLQEEKDALLTRRNTLLQEIQTYQNILMKENNSKTKNGDILQNDITQDFLNLISISSSNPNSAISDRKRVERINGLTNLQKELVTKYDTLPLLNMNLRLSYLRDHTYPHLQVSVQSRDRVHNDGIEVLVVNYKFCRNTMNPFEIQFKMFYKFEDSTLLKWEILRISTNVRLKAKQLLATRNFQKCLLSLYEFDKIKSKKTGIFQNLINLLKRKTRCYLMNNSDSLIVERVIREGRLTTIKLQINFIITMPGERGKPRNCFLPMSKISIALWKGGERFNQIDLDEICYGLIKEYGVKTGLKEICNVCLFPDMYAR 23B4CBD6AE26E793 cenpq_yeast Inner kinetochore subunit OKP1 OKP1 Outer kinetochore protein 1 YGR179C CENP-Q homolog Constitutive centromere-associated network protein OKP1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MAADRDNFLQNIENDSINNGQAMDLSPNRSSSESDSSILMNVNDIKTLRLDVAPEAKSTQSKKSLFYENSDDAEEGEIEERTNKEEGQYHHKGSKQLRFEVGKESTGKLQSHLSDGSATSGEGNVRPWEFRKVIQAEYRERLPRNYELKHWKKPSKIMIGSILRLLETNTVSALDSVFEKYEKEMNQMTHGDNNEVKRIYSKKERLLEIILTKIKKKLRQAKFPSRISERDLDIEYIYSKRQFIQNRYSQELQNNERLEAILSREQNLLEETRKLCMNLKTNNKKRLTEKLIQKDLHPVLNKAMEYTYGLESTNGFMHPDGPVTFRNDSHELNLMLNDPIKSTADVRLDKEEVLSLLPSLKEYTKKSKELKETMGQMISDSHEEEIKEVFVPHHESHQDKTEEDIH cenpk_yeast Inner kinetochore subunit MCM22 YJR135C J2122 MCM22 Minichromosome maintenance protein 22 CENP-K homolog Constitutive centromere-associated network protein MCM22 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDVEKDVLDVYIKNLENQIGNKRYFLKQAQGAIDEITKRSLDTEGKPVNSEVFTELLRKPMFFSERADPIGFSLTSNFLSLRAQSSSEWLSLMNDQSVDQKAMLLLQNNINSDLKELLRKLQHQMTIMDSKKQDHAHIRTRKARNKELWDSLADFLKGYLVPNLDDNDESIDSLTNEVMLLMKRLIEHDLNLTLNDFSSKTIPIYRLLLRANIITVIEGSTNPGTKYIKLIDFNETSLT cenpn_yeast Inner kinetochore subunit CHL4 CHL4 YDR254W YD9320A.04 CTF17 MCM17 Chromosome loss protein 4 Chromosome transmission fidelity protein 17 Minichromosome maintenance protein 17 CENP-N homolog Constitutive centromere-associated network protein CHL4 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSNELRLEDNYVPTSDTLVVFKQLMKLPVTVLYDLTLSWFAKFGGSFDGDIYLLTETLDLLIEKGVRRNVIVNRILYVYWPDGLNVFQLAEIDCHLMISKPEKFKWLPSKALRGDGKPYVVKLQPAKFIENLQTDLAKIYHCHVYMFKHPSLPVLITRIQLFDSNNLFLSTPNIGSINKESLYNKLDKFQGKPLISRRPYYVAFPLNSPIIFHSVDKDIYARLVLQSISRTISERETIIFKPVQKIPVKSIHNIMTLLGPSRFAESMGPWECYASANFERSPLHDYKKHQGLTGKKVMVREFDDSFLNDDENFYGKEEPEIRRLRLEKNMIKFKGSANGVMDQKYNDLKEFNEHVHNIRNGKKNEDSGEPVYISRYSSLVPIEKVGFTLKNEINSRIITIKLKFNGNDIFGGLHELCDKNLINIDKVPGWLAGENGSFSGTIMNGDFQREQVAKGGLL cbf3a_yeast Centromere DNA-binding protein complex CBF3 subunit A CEP2 CTF14 YGR140W CBF2 CBF3A NDC10 Chromosome transmission fidelity protein 14 Kinetochore protein CTF14 Centromere-binding factor 2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MRSSILFLLKLMKIMDVQQQQEAMSSEDRFQELVDSLKPRTAHQYKTYYTKYIQWCQLNQIIPTPEDNSVNSVPYKDLPISAELIHWFLLDTLITDDKPGEKREETEDLDEEEENSFKIATLKKIIGSLNFLSKLCKVHENPNANIDTKYLESVTKLHTHWIDSQKAITTNETNNTNTQVLCPPLLKVSLNLWNPETNHLSEKFFKTCSEKLRFLVDFQLRSYLNLSFEERSKIRFGSLKLGKRDRDAIIYHKVTHSAEKKDTPGHHQLLALLPQDCPFICPQTTLAAYLYLRFYGIPSVSKGDGFPNLNADENGSLLQDIPILRGKSLTTYPREETFSNYYTTVFRYCHLPYKRREYFNKCNLVYPTWDEDTFRTFFNEENHGNWLEQPEAFAFPDKIPFDFKKIMNFKSPYTSYSTNAKKDPFPPPKDLLVQIFPEIDEYKRHDYEGLSQNSRDFLDLMEVLRERFLSNLPWIYKFFPNHDIFQDPIFGNSDFQSYFNDKTIHSKGSPILSFDILPGFNKIYKNKTNFYSLLIERPSQLTFASSHNPDTHPTQKQESEGPLQMSQLDTTQLNELLKQQSFEYVQFQTLSNFQILLSVFNKIFEKLEMKKSSRGYILHQLNLFKITLDERIKKSKIDDADKFIRDNQPIKKEENIVNEDGPNTSRRTKRPKQIRLLSIADSSDESSTEDSNVFKKDGESIEDGAYGENEDENDSEMQEQLKSMINELINSKISTFLRDQMDQFELKINALLDKILEEKVTRIIEQKLGSHTGKFSTLKRPQLYMTEEHNVGFDMEVPKKLRTSGKYAETVKDNDDHQAMSTTASPSPEQDQEAKSYTDEQEFMLDKSIDSIEGIILEWFTPNAKYANQCVHSMNKSGNKSWRANCEALYKERKSIVEFYIYLVNHESLDRYKAVDICEKLRDQNEGSFSRLAKFLRKWRHDHQNSFDGLLVYLSN cbf3c_yeast Centromere DNA-binding protein complex CBF3 subunit C CTF13 CBF3C YMR094W YM9582.19 YM6543.01 Chromosome transmission fidelity protein 13 Kinetochore protein CTF13 protein protein yeast Saccharomyces cerevisiae Baker's yeast MPSFNPVRFLELPIDIRKEVYFHLDGNFCGAHPYPIDILYKSNDVELPGKPSYKRSKRSKKLLRYMYPVFATYLNIFEYSPQLIEKWLEYAFWLRYDCLVLDCFKVNHLYDGTLIDALEWTYLDNELRLAYFNKASMLEVWYTFKEYKKWVIDSVAFDELDLLNVSNIQFNIDNLTPQLVDKCLSILEQKDLFATIGEVQFGQDEEVGEEKDVDVSGANSDENSSPSSTIKNKKRSASKRSHSDNGNVGATHNQLTSISVIRTIRSMESMKSLRKITVRGEKLYELLINFHGFRDNPGKTISYIVKRRINEIRLSRMNQISRTGLADFTRWDNLQKLVLSRVAYIDLNSIVFPKNFKSLTMKRVSKIKWWNIEENILKELKVDKRTFKSLYIKEDDSKFTKFFNLRHTRIKELDKSEINQITYLRCQAIVWLSFRTLNHIKLQNVSEVFNNIIVPRALFDSKRVEIYRCEKISQVLVI 77B1C012FD74E56F cbf3b_yeast Centromere DNA-binding protein complex CBF3 subunit B CEP3 CBF3 YMR168C YM8520.17C CBF3B CSL1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MFNRTTQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTKLITASSSKEYLPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQKDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNHSVDGKYWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWEDGMQLVMCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLANSLLTQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPRKPIALHTEVSSLLQHAAYLQDLPNVDVYREENSTEVLYWKIISLDRDLDQYLNKSSKPPLKTLDAIRRELDIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWKLFKMYLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRHPMVMQTITRVVSFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTERLSKLKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLVPLNKLRQESLLEEEDENNTEPSDFRTIVEEFQSEYNISDILS 2E24A0508080A09B cenpa_yeast Histone H3-like centromeric protein CSE4 CSE4 Chromosome segregation protein 4 CENP-A homolog CSL2 YKL262 YKL049C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQRTRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVRTHSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI 0170A10060EEC309 bim1_yeast Protein BIM1 BIM1 YER016W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSAGIGESRTELLTWLNGLLNLNYKKIEECGTGAAYCQIMDSIYGDLPMNRVKFNATAEYEFQTNYKILQSCFSRHGIEKTVYVDKLIRCKFQDNLEFLQWLKKHWIRHKDESVYDPDARRKYRPIITNNSATKPRTVSNPTTAKRSSSTGTGSAMSGGLATRHSSLGINGSRKTSVTQGQLVAIQAELTKSQETIGSLNEEIEQYKGTVSTLEIEREFYFNKLRDIEILVHTTQDLINEGVYKFNDETITGHGNGNGGALLRFVKKVESILYATAEGFEMNDGEDELNDKNLGEHGTVPNQGGYANSNGEVNGNEGSNHDVIMQNDEGEVGVSNNLIIDEETF C9087CB46A32BD74 stu2_yeast Protein STU2 STU2 YLR045C L2108 Suppressor of tubulin 2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSGEEEVDYTTLPLEERLTYKLWKARLEAYKELNQLFRNSVGDISRDDNIQIYWRDPTLFAQYITDSNVVAQEQAIVALNSLIDAFASSSLKNAHNITLISTWTPLLVEKGLTSSRATTKTQSMSCILSLCGLDTSITQSVELVIPFFEKKLPKLIAAAANCVYELMAAFGLTNVNVQTFLPELLKHVPQLAGHGDRNVRSQTMNLIVEIYKVTGNNSDLLEEILFKKLKPIQVKDLHKLFAKVGDEPSSSKMLFEWEKRELEKKRSQEEEARKRKSILSNDEGEYQIDKDGDTLMGMETDMPPSKQQSGVQIDTFSMLPEETILDKLPKDFQERITSSKWKDRVEALEEFWDSVLSQTKKLKSTSQNYSNLLGIYGHIIQKDANIQAVALAAQSVELICDKLKTPGFSKDYVSLVFTPLLDRTKEKKPSVIEAIRKALLTICKYYDPLASSGRNEDMLKDILEHMKHKTPQIRMECTQLFNASMKEEKDGYSTLQRYLKDEVVPIVIQIVNDTQPAIRTIGFESFAILIKIFGMNTFVKTLEHLDNLKRKKIEETVKTLPNFSIASGSTHSTIETNKQTGPMENKFLLKKSSVLPSKRVASSPLRNDNKSKVNPIGSVASASKPSMVAANNKSRVLLTSKSLATPKNVVANSTDKNEKLIEEYKYRLQKLQNDEMIWTKERQSLLEKMNNTENYKIEMIKENEMLREQLKEAQSKLNEKNIQLRSKEIDVNKLSDRVLSLENELRNMEIELDRNKKRNDTNLQSMGTISSYSIPSSTVSSNYGVKSLSSALPFKEEEDVRRKEDVNYERRSSESIGDLPHRVNSLNIRPYRKNGTGVSSVSDDLDIDFNDSFASEESYKRAAAVTSTLKARIEKMKAKSRREGTTRT 7A49C3702E21C7BF sli15_yeast Inner centromere protein-related protein SLI15 YBR1206 YBR156C SLI15 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDWAIKAARKKTQRKPGSTRSIIETLDDLNNLTTDAHSEINQRLYESSEWLRNNVYMNTLKYEDKKMEESLISPENTHNKMDVEFPKMKGEYELSNSQNDAAKDVTKTPRNGLHNDKSITPKSLRRKEVTEGMNRFSIHDTNKSPVEPLNSVKVDANESEKSSPWSPYKVEKVLRESSKTSESPINTKRFDNQTWAAKEEMENEPILQALKKAESVKVKPPPNSGIARSQRRSNMFVPLPNKDPLIIQHIPPTKSSGSIPKVRTVKESPIAFKKKSTINSPAIRAVENSDTAGSTKASSVFDRLSSIPTKSFENKISRGNVGHKYSSSSIDLTGSPMKKVSQKFKSINSTDTDMQEALRDIFSVKNKITKNNSPKGKNSRKSSIPRFDKTSLKLTTHKKLAIIAEQKKKSKHSSDVHKTGSRPHSISPTKISVDSSSPSKEVKNYYQSPVRGYLRPTKASISPNKNKNLTTSQTPHRLKIKEKTLRKLSPNIADISKPESRKSKNYRLTNLQLLPPAEAERDDLKKKFDKRLSGIMRSQQEHHRRKQEKQKRMSHLEQDLKKQTSFSNDYKDIRLKESLAPFDNHVRDTINKNTAFSTDNILATINTVDHREIIGNVTPKIASVNDSLPEINTDSEDEASVTLAAWAKSPYLQEQLIRQQDINPQTIFGPIPPLHTDEIFPNPRLNRLKPRQIVPKRS 827AC2AB884BA7D1 bir1_yeast Protein BIR1 J1880 YJR089W BIR1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDGQIDKMEKRYSMTKLENRLRTFQDGVALEKKKLKWSFKVIPYQAMAKLGFYFDPVIDPKTSKLKKDSVRCCYCHRQTYNVRDCRSKRKDVLETLSNIMRQHLTVTDNKQVCLLIYLRNKLLTDYSFHMGVSDWKNDKYFSNPDDENVINLRKFTFQDNWPHSGSQNEHPLGIEKMVNAGLMRYDSSIEGLGDPSMDKTLMNDTCYCIYCKQLLQGWSINDDPMSRHYKVSQNGNCYFFQTRNRFERIKNDNDSITKNCEVSPTLGENGKREVINTKTASQRQCPLFESPPSSTGPQLDDYNEKTDISVIQHNISVLDGAQGENVKRNSVEEKEQINMENGSTTLEEGNINRDVLADKKEVISTPTAKEIKRPNVQLTQSSSPIKKKRKFKRISPRKIFDEEDSEHSLNNNSANGDNKDKDLVIDFTSHIIKNRDVGRKNAILDDSTDEFSFSNQGHNTFDIPIPTSSHLLKGIDSDNDNVIREDDTGINTDTKGASSKHEKFSVNSEEDLNFSEVKLTGRDSSTNILIRTQIVDQNLGDIDRDKVPNGGSPEVPKTHELIRDNSEKREAQNGEFRHQKDSTVRQSPDILHSNKSGDNSSNITAIPKEEQRRGNSKTSSIPADIHPKPRKNLQEPRSLSISGKVVPTERKLDNINIDLNFSASDFSPSSQSEQSSKSSSVISTPVASPKINLTRSLHAVKELSGLKKETDDGKYFTNKQETIKILEDVSVKNETPNNEMLLFETGTPIASQENKSRKLFDEEFSGKELDIPIDSSTVEIKKVIKPEFEPVPSVARNLVSGTSSYPRNSRLEEQRKETSTSLADNSKKGSSFNEGNNEKEPNAAEWFKIDENRHLVKNYFHDLLKYINNNDATLANDKDGDLAFLIKQMPAEELDMTFNNWVNLKVQSIKREFIDDCDKKLDILRRDYYTATNFIETLEDDNQLIDIAKKMGIL 6B20DC16065B4C39 mps1_yeast Serine/threonine-protein kinase MPS1 RPK1 D2785 YDL028C MPS1 Regulatory cell proliferation kinase 1 Monopolar spindle protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSTNSFHDYVDLKSRTNTRQFSDDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAERRSKRFLISNRTTKLGPAKRAMTLTNIFDEDVPNSPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLPTSDLPLISQIYFDKQREENRQAALRKHSSRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSSSSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISRNKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI mad1_yeast Spindle assembly checkpoint component MAD1 MAD1 Mitotic arrest deficient protein 1 YGL086W protein protein yeast Saccharomyces cerevisiae Baker's yeast MDVRAALQCFFSALSGRFTGKKLGLEIYSIQYKMSNSGGSSPFLESPGGSPDVGSTNGQSNRQIQALQFKLNTLQNEYEIEKLQLQKQTNILEKKYKATIDELEKALNDTKYLYESNDKLEQELKSLKERSANSMNDKDKCIEELRTTLQNKDLEMETLRQQYDSKLSKVTNQCDHFKLEAESSHSLLMKYEKEIKRQSVDIKDLQHQVMEKDDELSSVKASKMINSHPNYSTEEFNELTEMNKMIQDQVQYTKELELANMQQANELKKLKQSQDTSTFWKLENEKLQNKLSQLHVLESQYENLQLENIDLKSKLTKWEIYNDSDDDDDNNVNNNDNNNNNKNDNNNDNNNDTSNNNNINNNNRTKNNIRNNPEEIIRDWKLTKKECLILTDMNDKLRLDNNNLKLLNDEMALERNQILDLNKNYENNIVNLKRLNHELEQQKSLSFEECRLLREQLDGLYSAQNNALLEVENSETHASNKNVNEDMNNLIDTYKNKTEDLTNELKKLNDQLLSNSNDVETQRKKRKLTSDQIGLNYSQRLNELQLENVSVSRELSKAQTTIQLLQEKLEKLTKLKEKKIRILQLRDGPFIKDQFIKKNKLLLLEKENADLLNELKKNNPAVETVPISVYDSLNFELKQFEQEVFKSNKRFSRLKQVFNNKSLEFIDVVNSLLGFKLEFQQDSRVKIFSCFKPEKYLIADLNENTLKSNLDADIEGWDDLMNLWVEDRGQLPCFLATITLRLWEQRQAK mad3_yeast Spindle assembly checkpoint component MAD3 MAD3 YJL013C J1341 Mitotic MAD3 protein protein protein yeast Saccharomyces cerevisiae Baker's yeast MKAYAKKRISYMPSSPSQNVINFEEIETQKENILPLKEGRSAAALSKAIHQPLVEINQVKSSFEQRLIDELPALSDPITLYLEYIKWLNNAYPQGGNSKQSGMLTLLERCLSHLKDLERYRNDVRFLKIWFWYIELFTRNSFMESRDIFMYMLRNGIGSELASFYEEFTNLLIQKEKFQYAVKILQLGIKNKARPNKVLEDRLNHLLRELGENNIQLGNEISMDSLESTVLGKTRSEFVNRLELANQNGTSSDVNLTKNNVFVDGEESDVELFETPNRGVYRDGWENFDLKAERNKENNLRISLLEANTNLGELKQHEMLSQKKRPYDEKLPIFRDSIGRSDPVYQMINTKDQKPEKIDCNFKLIYCEDEESKGGRLEFSLEEVLAISRNVYKRVRTNRKHPREANLGQEESANQKEAEAQSKRPKISRKALVSKSLTPSNQGRMFSGEEYINCPMTPKGRSTETSDIISAVKPRQLTPILEMRESNSFSQSKNSEIISDDDKSSSSFISYPPQR 36550249D81BB6D1 bub1_yeast Checkpoint serine/threonine-protein kinase BUB1 YGR188C G7542 BUB1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MNLDLGSTVRGYESDKDTFPQSKGVSSSQKEQHSQLNQTKIAYEQRLLNDLEDMDDPLDLFLDYMIWISTSYIEVDSESGQEVLRSTMERCLIYIQDMETYRNDPRFLKIWIWYINLFLSNNFHESENTFKYMFNKGIGTKLSLFYEEFSKLLENAQFFLEAKVLLELGAENNCRPYNRLLRSLSNYEDRLREMNIVENQNSVPDSRERLKGRLIYRTAPFFIRKFLTSSLMTDDKENRANLNSNVGVGKSAPNVYQDSIVVADFKSETERLNLNSSKQPSNQRLKNGNKKTSIYADQKQSNNPVYKLINTPGRKPERIVFNFNLIYPENDEEFNTEEILAMIKGLYKVQRRGKKHTEDYTSDKNRKKRKLDVLVERRQDLPSSQPPVVPKSTRIEVFKDDDNPSQSTHHKNTQVQVQTTTSILPLKPVVDGNLAHETPVKPSLTSNASRSPTVTAFSKDAINEVFSMFNQHYSTPGALLDGDDTTTSKFNVFENFTQEFTAKNIEDLTEVKDPKQETVSQQTTSTNETNDRYERLSNSSTRPEKADYMTPIKETTETDVVPIIQTPKEQIRTEDKKSGDNTETQTQLTSTTIQSSPFLTQPEPQAEKLLQTAEHSEKSKEHYPTIIPPFTKIKNQPPVIIENPLSNNLRAKFLSEISPPLFQYNTFYNYNQELKMSSLLKKIHRVSRNENKNPIVDFKKTGDLYCIRGELGEGGYATVYLAESSQGHLRALKVEKPASVWEYYIMSQVEFRLRKSTILKSIINASALHLFLDESYLVLNYASQGTVLDLINLQREKAIDGNGIMDEYLCMFITVELMKVLEKIHEVGIIHGDLKPDNCMIRLEKPGEPLGAHYMRNGEDGWENKGIYLIDFGRSFDMTLLPPGTKFKSNWKADQQDCWEMRAGKPWSYEADYYGLAGVIHSMLFGKFIETIQLQNGRCKLKNPFKRYWKKEIWGVIFDLLLNSGQASNQALPMTEKIVEIRNLIESHLEQHAENHLRNVILSIEEELSHFQYKGKPSRRF 6D76FC980775D3F9 cep3_hhv6u Cytoplasmic envelopment protein 3 17R U71 protein protein hhv6u Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) Human B lymphotropic virus MGAKCCKPVSCGMCKKTENTLIDYKGNPILLANEFTVLTDTESEEEGMADLEKPLLEKVVAKCDTEAEKKLPCKSKK spc19_yeast DASH complex subunit SPC19 SPC19 19 kDa spindle pole component protein Outer kinetochore protein SPC19 YDR201W protein protein yeast Saccharomyces cerevisiae Baker's yeast MTDALEQSVLALEGTVSVLKDSVESLKCANEPSTNLASTMLQTKRVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQRELDTLQQTYELNDLRLKKNISMDDDDALNSPDMGQEYEGRDADDVVMMASSTNEELEELKKLKEKKKQLENKLEILKQK 74615FE2186DAFE6 dad1_yeast DASH complex subunit DAD1 DAD1 Outer kinetochore protein DAD1 DUO1 and DAM1-interacting protein 1 YDR016C protein protein yeast Saccharomyces cerevisiae Baker's yeast MMASTSNDEEKLISTTDKYFIEQRNIVLQEINETMNSILNGLNGLNISLESSIAVGREFQSVSDLWKTLYDGLESLSDEAPIDEQPTLSQSKTK dad2_yeast DASH complex subunit DAD2 YKR083C YKR403 HSK1 DAD2 Outer kinetochore protein DAD2 DUO1 and DAM1-interacting protein 2 Helper of ASK1 protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDSIDEQIAIKRKELQSLQKITSLTDGLKIQLTELNEQIKEMGMNADSVAQLMNNWDSIINNISQASLGLLQYAEGDYEIGPWKDSKKKESEQSNETGLEAQENDKNDEDNDEDEDLVPLPETMVRIRVDGNE 82730D4AA5B66951 ady3_yeast Accumulates dyads protein 3 YDL239C ADY3 protein protein yeast Saccharomyces cerevisiae Baker's yeast MNHWLAFLNKPESLKEQNSDCDQQGEMRHVTDGTLTKSPESKPFRERRSQTWIDSEVPTSTEKSNVQESISSDIISKLSNRRSRRNRSESWAGSEASSPSGNISTLENATEKNTLKSPNKFLQRGGLPTVGIGSQALSPAGKPSTLGNVSPGKFTTYKVHNSIEVNRFSSTPTKLLTNPHKVAAISNDEHYVVSNESLEENIEVAHLENVFRSSKTPDEEQSEYMKLGEIRLSSSSYGGSISKENSLPKVLDELQSQNEEIKALRQKLEEKDDRIQELEELNSMNDAKLQRIEDLQKEFHNERKAASKRLNIVQDRFRKEIKKIREEKITDFQNKNASKKEKNEVTSAKTKCKAFSQRNILVSELYRKQKQILNLQQENDKFLKDINESNNSIVKLRSEVEILKSNLQLSQDENKKLHDNGSFYEKRLNDVYSYMQNLSLFEKDLGKFILEEMKCGHSPSMFQNGFAKLYPDFQDIKNLENMEQYKQLKGKIELLEKNDRIRLEKIISVFKLINERLHFMQQQHSHKIKYLQKEALTKEQQFRLEKRRWHDILNLKEENFQKLKSELKEKLILSEKIQKNAEDKLNDYMNEHQEIVEKLQNQALIASRWSTQIQESENTHKKITDELAGKQSEILKLEETILSLKEDVFQEKLNLKKLYGDPSTELNFETVGKSFPHITKEKYDSLGLDILTDLTYVQSQNLIKNLLIVLDIPLKTFLKIVPTIVIQLRCELTLLTKFANDLNLKVFGKQLDFKSRRKVAMNEFLNNHDIAEVKHPLEYDLQALFKYFFS 46F17474F30FD3D9 spo1_yeast Putative meiotic phospholipase SPO1 SPO1 YNL012W N2858 Sporulation-specific protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMNDYGLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEYNDNDLKMKKRQGGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKRNLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWGKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNGLLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSGKAEKCINNFDDLGFITATSSSIFNNVLIFIWNLASQSSREAMKALNMVMGIFGLGKEEIFSISKDSSRLETDYAVYQPNPFYLYPEKDNVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSDIDNYPNGSKLKRIFEKLDEENVHYQFPNNVKTFTHPIVIGCNATKRTGHDSFLPIIIYHANANHGNASNTSTFKITYNQSEVSSMLPTGRGVFSNDYDLYYKNCLGCILTKRTMDRLPRKKKFSPFCLQCFKDYCYS 2861BD03FB19C2D3 ecm11_yeast Protein ECM11 ECM11 YDR446W D9461.31 Extracellular mutant protein 11 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTVIKTEPTTEVTLYSPPSKESLSKDDAHRKKQNNKPPSSINSRSGPNKHKLAAKAPEKKINNTDKQDLSAFLLNPSLIVKPSESKKKENIVAYNDTPGIKTEHTAFQPLTPISKKRALKEKAASEKCDSFDLSRDEKPYIQKKSKTLSSVTEINSSEYKLSLNGENTSSPAKEKSQEPIENPGSYQKTRNYLFEKPDPLDTCLQDYSSMLPSNVAEEDQEYFISVADSTLEEWTNKGQEIIDQQFQLYQEIIKKRIELSYKFKGIISVINDRADALEEQGQQLEGKIKKVKTLANEILNII CB6890F4EE069232 nup82_yeast Nucleoporin NUP82 NUP82 YJL061W J1135 HRB187 Nuclear pore protein NUP82 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSQSSRLSALPIFQASLSASQSPRYIFSSQNGTRIVFIQDNIIRWYNVLTDSLYHSLNFSRHLVLDDTFHVISSTSGDLLCLFNDNEIFVMEVPWGYSNVEDVSIQDAFQIFHYSIDEEEVGPKSSIKKVLFHPKSYRDSCIVVLKEDDTITMFDILNSQEKPIVLNKPNNSFGLDARVNDITDLEFSKDGLTLYCLNTTEGGDIFAFYPFLPSVLLLNEKDLNLILNKSLVMYESLDSTTDVIVKRNVIKQLQFVSKLHENWNSRFGKVDIQKEYRLAKVQGPFTINPFPGELYDYTATNIATILIDNGQNEIVCVSFDDGSLILLFKDLEMSMSWDVDNYVYNNSLVLIERVKLQREIKSLITLPEQLGKLYVISDNIIQQVNFMSWASTLSKCINESDLNPLAGLKFESKLEDIATIERIPNLAYINWNDQSNLALMSNKTLTFQNISSDMKPQSTAAETSISTEKSDTVGDGFKMSFTQPINEILILNDNFQKACISPCERIIPSADRQIPLKNEASENQLEIFTDISKEFLQRIVKAQTLGVSIHNRIHEQQFELTRQLQSTCKIISKDDDLRRKFEAQNKKWDAQLSRQSELMERFSKLSKKLSQIAESNKFKEKKISHGEMKWFKEIRNQILQFNSFVHSQKSLQQDLSYLKSELTRIEAETIKVDKKSQNEWDELRKMLEIDSKIIKECNEELLQVSQEFTTKTQ C379B5E111E26B50 lcp5_yeast U3 small nucleolar ribonucleoprotein protein LCP5 SYGP-ORF43 YER127W LCP5 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSELNALLKDINGSLTATSESLERLSGIYSNSATDEIPESNQLHEHLFYDAKKPAEKVSLLSLKNGSMLGYINSLLMLIGNRLDDECKDPSAMDARERSIQHRVVLERGVKPLEKKLAYQLDKLTRAYVKMEKEYKDAEKRALEKSTLVNHSGNDDSEDDESSEDEIAYRPNTSGIINTNKKSSAYRVEETAKQENGEENDDNETGVYKPPKITAVLPPQQTHFEDRFDAREHKDRSNKSRMQAMEEYIRESSDQPDWSASIGADIVNHGRGGIKSLRDTEKERRVTSFEEDNFTRLNITNKAEKRKQKQRERNARMNVIGGEDFGIFSSKRKLEDSTSRRGAKKTRSAWDRAQRRL 77B7F3F126036489 med21_yeast Mediator of RNA polymerase II transcription subunit 21 SRB7 YDR308C D9740.17 MED21 Mediator complex subunit 21 RNAPII complex component SRB7 Suppressor of RNA polymerase B 7 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTDRLTQLQICLDQMTEQFCATLNYIDKNHGFERLTVNEPQMSDKHATVVPPEEFSNTIDELSTDIILKTRQINKLIDSLPGVDVSAEEQLRKIDMLQKKLVEVEDEKIEAIKKKEKLLRHVDSLIEDFVDGIANSKKST C5B3474AF8DD662A ste50_yeast Protein STE50 STE50 YCL32W YCL032W protein protein yeast Saccharomyces cerevisiae Baker's yeast MEDGKQAINEGSNDASPDLDVNGTILMNNEDFSQWSVDDVITWCISTLEVEETDPLCQRLRENDIVGDLLPELCLQDCQDLCDGDLNKAIKFKILINKMRDSKLEWKDDKTQEDMITVLKNLYTTTSAKLQEFQSQYTRLRMDVLDVMKTSSSSSPINTHGVSTTVPSSNNTIIPSSDGVSLSQTDYFDTVHNRQSPSRRESPVTVFRQPSLSHSKSLHKDSKNKVPQISTNQSHPSAVSTANTPGPSPNEALKQLRASKEDSCERILKNAMKRHNLADQDWRQYVLVICYGDQERLLELNEKPVIIFKNLKQQGLHPAIMLRRRGDFEEVAMMNGSDNVTPGGRL EFC7D14F2940C779 mkk2_yeast MAP kinase kinase MKK2/SSP33 MKK2 SSP33 YPL140C LPI6C protein protein yeast Saccharomyces cerevisiae Baker's yeast MASMFRPPESNRSHQKTPKLTLPVNLVQNAKSTNDGQHLNRSPYSSVNESPYSNNSTSATSTTSSMASNSTLLYNRSSTTTIKNRPVPPPLPPLVLTQKKDGIEYRVAGDSQLSERFSNLHVDITYKELLSSAPISTKLSNIDTTFIKKDLDTPEGEDSYPSTLLSAYDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEEEAWRFGHLKDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQMKKKVNMERFVKKCWEKEKDGI 8EACED6C742E148B bmh1_yeast Protein BMH1 YER177W BMH1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSTSREDSVYLAKLAEQAERYEEMVENMKTVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELICSYRSKIETELTKISDDILSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMSESGQAEDQQQQQQHQQQQPPAAAEGEAPK 0A234167E313688B kel2_yeast Kelch repeat-containing protein 2 KEL2 G8585 YGR238C protein protein yeast Saccharomyces cerevisiae Baker's yeast MVPFKLTNKVPTDTGPSLISAQSVPRPIVFMDNRNNTRIVTPTLPPNQHRGISGASTALPWSPESKNTGKYIWNRVKLKNSPFPRYRHSSSFIVTNDNRIFVTGGLHDQSVYGDVWQIAANADGTSFTSKRIDIDQNTPPPRVGHASTICGNAYVVFGGDTHKLNKNGLLDDDLYLFNINSYKWTIPQPIGRRPLGRYGHKISIIASNPMQTKLYLFGGQVDETYFNDLVVFDLSSFRRPNSHWEFLEPVGDLPPPLTNHTMVAYDNKLWVFGGETPKTISNDTYRYDPAQSEWSKVKTTGEKPPPIQEHASVVYKHLMCVLGGKDTHNAYSNDVYFLNLLSLKWYKLPRMKEGIPQERSGHSLTLMKNEKLLIMGGDKTDYASPNIHDLQTSETDQGEGTLLYTLDLSSLNELCPGIMCESLHAGESFSNSLSGGFTPSKSTESENQEIINILTPRLPDSKVLSYNDIDEGAGSYSSALDDKAFERKSDREEKKPQSSKVDSSINKESPGTGIKVSKKNFPVLRGLTVDSEEYGSSSYKDTSCQKGIPKNLFDDLNLNLQTLRLEAQQKELETARHISQLEKEVQRLMVIKEASKDSNFQTARLKNLEIQKTFLESRINDLKNLLMVKLSQASKLCDQITIQNNGLKTCSEHVTIKRDIIDLENKCDVLKRQNEILVNNMQKITPELHTYLNESSCYLGKLLKSYPTSARPPSSEKDNQIYEKDSLNKIEKVINEMHETVRAKEKLHLETQKLNDERDSLRANLLDNNNKLDALRKLSDGSSKSMDLTKKAIHLSQSELEKYRKNNDDLQKEIDRIKTEQAEQDDKQEQRGAITHGNFDAFHRMKINNLKAELYMSKENRDSLKDELLALKKKLYTLEQKK 63B9772FF017E6D9 bud6_yeast Bud site selection protein 6 BUD6 Actin-interacting protein 3 AIP3 L8543.5 YLR319C protein protein yeast Saccharomyces cerevisiae Baker's yeast MKMAVDDPTYGTPKIKRTASSSSSIETTVTKLLMSTKHLLQVLTQWSKGTTSGRLVSDAYVQLGNDFKVVSKFFMHAKVDMSDVGDVPMALRRVLEVTLREPPSDETLNKHLPKIREIIVTLLDKLKVKQAILKNMQQEHRISVKSHHQQNPSFTSNLSLGSEGTREGTPLSSRKSSIVRDQRQSDSVENSYGEKVNSTSTGTPSAQSAEATLTKPRTNIKQNLKSNNAPNASDDDDALSQLKKGTNLQRRASKRYSAYHMAKLTNQSTTEAAAAAGLMTTPSPSMLHLEETVRKSKLYGNNNNDDDRNINSAENKGKSIDDVSKASPLAKTPLPIENVRASPRRLSSVVTTSPDKAMNGTCPVFLRIGDKTKKCHVQLPTTKNALRLLFIERFAYSPGANSFPDIYIMDPQYGVFYELEELNLLDIKEGFVIELKLEENPNNTIKEFIDTVKMEISNSQNDIIRHLKEMSFGSAISGKQTEVLPQPGLEANKHDLVGQNKKDDDKTIKDIQYELGKIKQVHNINRSNINETIFNILRKVDNFKSLSFSAKNSSNRMYMEKSQTELGDLSDTLLSKVDDLQDVIEIMRKDVAERRSQPAKKKLETVSKDLENAQADVLKLQEFIDTEKPHWKKTWEAELDKVCEEQQFLTLQEELILDLKEDLGKALETFDLIKLCCEEQEKNPSRSKSNPILPIMRPGTFNQVREQVMVAVQSLNPDHDSRVEAIDKAEKMWEMERKLKASNEFDDELENFVGNSNLKKSGGFEEVERIRKQKDEANLRAYFGPGFT 4BAE8F541B8BDF1F not5_yeast General negative regulator of transcription subunit 5 NOT5 YP9499.27 YPR072W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSQRKLQQDIDKLLKKVKEGIEDFDDIYEKFQSTDPSNSSHREKLESDLKREIKKLQKHRDQIKTWLSKEDVKDKQSVLMTNRRLIENGMERFKSVEKLMKTKQFSKEALTNPDIIKDPKELKKRDQVLFIHDCLDELQKQLEQYEAQENEEQTERHEFHIANLENILKKLQNNEMDPEPVEEFQDDIKYYVENNDDPDFIEYDTIYEDMGCEIQPSSSNNEAPKEGNNQTSLSSIRSSKKQERSPKKKAPQRDVSISDRATTPIAPGVESASQSISSTPTPVSTDTPLHTVKDDSIKFDNSTLGTPTTHVSMKKKESENDSEQQLNFPPDRTDEIRKTIQHDVETNAAFQNPLFNDELKYWLDSKRYLMQPLQEMSPKMVSQLESSLLNCPDSLDADSPCLYTKPLSLPHPTSIFFPNEPIRFVYPYDVPLNLTNNENDTDNKFGKDSKAKSKKDDDIYSRTSLARIFMKFDLDTLFFIFYHYQGSYEQFLAARELFKNRNWLFNKVDRCWYYKEIEKLPPGMGKSEEESWRYFDYKKSWLARRCGNDFVYNEEDFEKL 073137119B3E92BC yap7_yeast AP-1-like transcription factor YAP7 YOL028C YAP7 protein protein yeast Saccharomyces cerevisiae Baker's yeast MRQRRSVVAVSVKPKGFKLGHKQGSMSTTSPPPSSPDGNVSTSGPSAIKLSKNWELPQRLKPGRKPKSKRGDASANNDGSSKIKKVQTSNQKDQMTTKDHENEGAKGHEGKSDDEGNGSGDENGVDSVEKRRRQNRDAQRAYRERRTTRIQVLEEKVEMLHNLVDDWQRKYKLLESEFSDTKENLQKSIALNNELQKALPLIVNTPFQQQPENPPDNPISILEMVENFKPIGAVSLKKGKLKAHC EBA1C0C0E868E45C cog3_yeast Conserved oligomeric Golgi complex subunit 3 COG3 GRD20 SEC34 Component of oligomeric Golgi complex 3 Protein SEC34 YER157W protein protein yeast Saccharomyces cerevisiae Baker's yeast MARSRKNSLVRDIASHPTIPESQTIVGLLDDSYLFDKLKKLSLAVENSDSLQRTDVSEGCSEVNGSEATTSADVKKTNKYLYYTTYLDQLNIKIDEYKVVLDQTRQVNDQLDSSIKKFRKISQDTGAFIEETKTIYEKQSKLSNLTESIPKALHYFEVLDPIMRRLNHATSPAIVKKSSFTTMLATIDESLRFLDENSDLKDAAAYRIKFKQCLIRACELISHFLTNLLKQTNQEILDKTKNKNSLTGLPSTTRDAFLYSKFYTIADTFKIQVSEIVKRSNEKAYNKYHDELNSILYECFNHYFQTRLRLLTPVIWSHIDEIVVKDKDQGLVKFIQDGKVYFQQLCADEYKLFVEFFPEKECRFKINQWFLQLCEPLYDSIRVRVLKETDICTLCDSVTLFAPYYEFEEGSEEYVKQFTDIQYDKLFEPIVQKVQARLILRVQIYVQQNILSYRPTRDVFMISNRRRKSKTSLQGGNEDATTSDDNPDPLLESYLSSFKNRSILPISPNDADDKSIDSEESTDKISQLQTYYPPLLKTLALLSKIYEMINSVVFDDLAHHVVHDCIVSLRNAYDMVIKSSAGKSDFNNLDISLAYLKNLLMLRDSIQNFNIQYTVNETYLDFSGVEGFFKSLKENGRNVLKKTKSSSILTLARELVPKVVNNMVDARTELISELRNVIKDFTESTSLELIDDTLDINSDEDLLSKNVKLRENIKARLPRIYEQILNYIDDQEIVTNLLDAVQELITQSYSKYYETITELAENGKFAKDQVADVMYLDVFTDFFAKEVADLLRNGDIDTITK C7AFBE99010FE571 atg17_yeast Autophagy-related protein 17 ATG17 APG17 YLR423C protein protein yeast Saccharomyces cerevisiae Baker's yeast MNEADVTKFVNNARKTLTDAQLLCSSANLRIVDIKKKLSSWQLSISKLNFLIVGLRQQGKFLYTILKEGIGTKLIQKQWNQAVLVVLVDEMKYWQYEITSKVQRLDGIVNELSISEKDDTDPSKLGDYISRDNVNLLNDKLKEVPVIERQIENIKLQYENMVRKVNKELIDTKLTDVTQKFQSKFGIDNLMETNVAEQFSRELTDLEKDLAEIMNSLTQHFDKTLLLQDKKIDNDEREELFKVVQGDDKELYNIFKTLHEVIDDVDKTILNLGQFLQAKIKEKTELHSEVSEIINDFNRNLEYLLIFKDISNLIDSFKNSCTQDIQTTKELCEFYDNFEESYGNLVLEAKRRKDVANRMKTILKDCEKQLQNLDAQDQEERQNFIAENGTYLPETIWPGKIDDFSSLYTLNYNVKNP 71504B6C76549B75 she1_yeast Mitotic spindle-associated protein SHE1 YBL031W YBL0420 SHE1 Sensitive to high expression protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MNDKLQEEHNEKDTTSQINGFTPPHMSIDFHSNNNSNIIETIGVSKRLGNSVLSELDSRASSKFEFLKDQSEQQYNGDKNNEPKSGSYNINEFFQAKHDSQFGQMESLDTHYTLLHTPKRKSQHAIPQDRSDSMKRSRPSRSIPYTTPVVNDITRRIRRLKLRNSLVNGNDIVARARSMQANSNINSIKNTPLSKPKPFMHKPNFLMPTTNSLNKINSAHRNTSSSSTASSIPRSKVHRSISIRDLHAKTKPVERTPVAQGTNSQLKNSVSVFDRLYKQTTFSRSTSMNNLSSGTSAKSKEHTNVKTRLVKSKTSGSLSSNLKQSTATGTKSDRPIWR kxd1_yeast Biogenesis of lysosome-related organelles complex 1 subunit KXD1 YGL079W KXD1 KxDL homolog protein protein yeast Saccharomyces cerevisiae Baker's yeast MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC 61541771FBEC8F8C cenph_yeast Inner kinetochore subunit MCM16 Minichromosome maintenance protein 16 MCM16 YPR046W CENP-H homolog Constitutive centromere-associated network protein MCM16 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTNSSEKQWERIQQLEKEHVEVYRELLITLDRLYLIRKHNHAVILSHTQQRLLEIRHQLQINLEKTALLIRLLEKPDNTNVLFTKLQNLLEESNSLDYELLQSLGAQSSLHKQLIESRAERDELMSKLIELSSKFPKPTIPPDDSDTAGKQVEVEKENETIQELMIALQIHSGYTNISYTI dam1-dam1-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-duo1-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173147 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-spc34-1 Interaction detected by GST pull-down 173142 N/A 173148 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-ndc80-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173149 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-ctf19-1 Interaction detected by GST pull-down 173142 N/A 173150 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-okp1-1 Interaction detected by GST pull-down 173142 N/A 173151 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-mcm22-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173152 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-mcm17-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173153 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-ndc10-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173154 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-ctf13-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173155 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-cep3-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173156 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-cse4-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173157 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-bim1-1 Interaction detected by GST pull-down 173142 N/A 173158 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-stu2-1 Interaction detected by GST pull-down 173142 N/A 173159 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-sli15-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173160 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-bir1-1 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173161 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false dam1-mps1-1 Interaction detected by GST pull-down 173142 N/A 173162 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-mad1-1 Interaction detected by GST pull-down 173142 N/A 173163 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-mad3-1 Interaction detected by GST pull-down 173142 N/A 173164 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-bub1-1 Interaction detected by GST pull-down 173142 N/A 173165 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false dam1-bub2-1 Interaction detected by GST pull-down 173142 N/A 173166 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Dam1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false spc34-dam1-3 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role prey prey in vitro In vitro N/A 173148 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Spc34 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false Spc34 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. spc34-duo1-2 Interaction detected by GST pull-down 173142 N/A 173148 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Spc34 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173147 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false Spc34 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. spc34-spc34-2 Interaction detected by GST pull-down 173142 N/A 173148 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Spc34 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173148 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false Spc34 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. spc34-spc19-2 Interaction detected by GST pull-down 173142 N/A 173148 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Spc34 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173167 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false Spc34 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. spc19-spc34-3 Interaction detected by GST pull-down 173142 N/A 173167 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Spc19 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false ecobb Escherichia coli (strain B / BL21) N/A 173148 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false Spc19 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. duo1-dam1-3 Interaction detected by GST pull-down 173142 N/A 173146 unspecified role unspecified role prey prey in vitro In vitro N/A 173147 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Duo1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false Duo1 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. duo1-duo1-1 Interaction detected by GST pull-down 173142 N/A 173147 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Duo1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173147 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false Duo1 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. duo1-spc34-3 Interaction detected by GST pull-down 173142 N/A 173147 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Duo1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173148 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false Duo1 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. duo1-dad1-2 Interaction detected by GST pull-down 173142 N/A 173168 unspecified role unspecified role prey prey in vitro In vitro N/A 173147 unspecified role unspecified role bait bait n-terminus N-terminus GST tagged protein Duo1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false Duo1 is part of the Dam1 kinetochore subcomplex containig 9 subunits and interacting with several other kinetochore related complexes and proteins. dam1-dam1-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-duo1-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173147 unspecified role unspecified role prey prey physical association physical association false false false dam1-spc34-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173148 unspecified role unspecified role prey prey physical association physical association false false false dam1-spc19-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173167 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-dad1-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173168 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-dad2-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173169 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-ndc80-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173149 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-bim1-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173158 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-sli15-2 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173160 unspecified role unspecified role prey prey physical association physical association false false false dam1-ady3-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173170 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-spo1-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173171 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-ecm11-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173172 unspecified role unspecified role prey prey physical association physical association false false false dam1-nup82-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait P53267:p.[Ser20Ala;Ser257Ala;Ser265Ala;Ser292Ala] mutation causing mutation causing an interaction mutation enabling interaction mutation causing mutation causing an interaction certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false N/A 173173 unspecified role unspecified role prey prey physical association physical association false false false dam1-lpc5-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173174 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-srb7-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait P53267:p.[Ser20Asp;Ser257Asp;Ser265Asp;Ser292Asp] mutation causing mutation causing an interaction mutation enabling interaction mutation causing mutation causing an interaction certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false N/A 173175 unspecified role unspecified role prey prey physical association physical association false false false dam1-ste50-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173176 unspecified role unspecified role prey prey physical association physical association false false false dam1-mkk2-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173177 unspecified role unspecified role prey prey physical association physical association false false false dam1-bmh1-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173178 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait ser20asp,ser257asp,ser265asp,ser292asp mutation causing mutation causing an interaction mutation enabling interaction mutation causing mutation causing an interaction certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false dam1-kel2-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173179 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-bud6-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173180 unspecified role unspecified role prey prey physical association physical association false false false dam1-not5-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173181 unspecified role unspecified role prey prey physical association physical association false false false dam1-yap7-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173182 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-sec34-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173183 unspecified role unspecified role prey prey physical association physical association false false false dam1-apg17-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait N/A 173184 unspecified role unspecified role prey prey physical association physical association false false false dam1-she1-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173185 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-ygl079w-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173186 unspecified role unspecified role prey prey N/A 173146 unspecified role unspecified role bait bait physical association physical association false false false dam1-mcm16-1 Interaction detected by classical yeast two-hybrid 173143 N/A 173146 unspecified role unspecified role bait bait undefined mutation Mutations S20D, S257D, S265D and S292D mimicking constitutive phosphorylation mutation mutation certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false N/A 173187 unspecified role unspecified role prey prey physical association physical association false false false dad1-dam1-1 Interaction detected by coimmunoprecipitation 173144 N/A 173146 unspecified role unspecified role prey prey N/A 173149 unspecified role unspecified role prey prey N/A 173168 unspecified role unspecified role bait bait c-terminus C-terminus protein S tagged Dad1 tag tag certain certain sequence position certain certain certain sequence position certain false association association false false false Fig. 4 spc34-dam1-1 Interaction detected by coimmunoprecipitation 173144 N/A 173146 unspecified role unspecified role prey prey N/A 173148 unspecified role unspecified role bait bait c-terminus C-terminus protein S tagged Spc34 tag tag certain certain sequence position certain certain certain sequence position certain false N/A 173149 unspecified role unspecified role prey prey association association false false false Fig. 4 dam1-cbf2-1 Interaction detected by S protein pull-down 173145 N/A 173155 unspecified role unspecified role prey prey in vitro In vitro N/A 173157 unspecified role unspecified role prey prey in vitro In vitro N/A 173151 unspecified role unspecified role prey prey in vitro In vitro N/A 173150 unspecified role unspecified role prey prey in vitro In vitro N/A 173154 unspecified role unspecified role prey prey in vitro In vitro N/A 173146 unspecified role unspecified role bait bait c-terminus C-terminus protein S tagged Dam1 s tag s tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 173149 unspecified role unspecified role prey prey in vitro In vitro association association false false false Fig. 3