IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ siaud-2004-1 Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Siaud N., Dray E., Gy I., Gerard E., Takvorian N., Doutriaux MP. EMBO J. (0261-4189) 2004 siaud-2004-2 Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Siaud N., Dray E., Gy I., Gerard E., Takvorian N., Doutriaux MP. Directed yeast two hybrid Figure 2 doutriau@ibp.u-psud.fr EMBO J. (0261-4189) 2004 brc2a_arath Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A BRCA2A BRCA5(IV) F6N15.14/F6N15.15 At4g00020/At4g00010 protein protein arath Arabidopsis thaliana (Mouse-ear cress) Mouse-ear cress MSTWQLFPDSSGDGFRWEVAGRILQSVSDSTPTKALESTAPLPSMADLLLQGCSKLIAREEAMPGEIPMFRTGLGKSVVLKESSIAKAKSILAEKVTYSDLRNTNCSIPQMRQVDTAETLPMFRTASGKSVPLKESSIAKAMSILGSDKIIDSDNVLPRESGFGVSNSLFQTASNKKVNVSSAGLARAKALLGLEEDDLNGFNHVNQSSSSSQQHGWSGLKTHEEFDATVVKHHSGTPGQYEDYVSGKRSEVLNPSLKVPPTKFQTAGGKSLSVSAEALKRARNLLGDPELGSFFDDVAGGDQFFTPEKDERLSDIAINNGSANRGYIAHEEKTSNKHTPNSFVSPLWSSSKQFSSVNLENLASGGNLIKKFDAAVDETDCALNATHGLSNNRSLASDMAVNNSKVNGFIPRGRQPGRPADQPLVDITNRRDTAYAYNKQDSTQKKRLGKTVSVSPFKRPRISSFKTPSKKHALQASSGLSVVSCDTLTSKKVLSTRYPEKSPRVYIKDFFGMHPTATTRMDYVPDHVRRIKSSNADKYVFCDESSSNKVGAETFLQMLAESGASLQHASRKWVTNHYRWIVWKLACYDIYYPAKCRGNFLTITNVLEELKYRYEREVNHGHCSAIKRILSGDAPASSMMVLCISAINPKTDNDSQEAHCSDSCSNVKVELTDGWYSMNAALDVVLTKQLNAGKLFVGQKLRILGAGLSGWATPTSPLEAVISSTICLLLNINGTYRAHWADRLGFCKEIGVPLALNCIKCNGGPVPKTLAGIKRIYPILYKERLGEKKSIVRSERIESRIIQLHNQRRSALVEGIMCEYQRGINGVHSQNDTDSEEGAKIFKLLETAAEPEFLMAEMSPEQLRSFTTYKAKFEAAQQMRKEKSVAETLEDAGLGERNVTPFMRIRLVGLTSLSYEGEHNPKEGIVTIWDPTERQRTELTEGKIYMMKGLVPINSDSEILYLHARGSSSRWQPLSPKDSENFQPFFNPRKPISLSNLGEIPLSSEFDIAAYVVYVGNAYTDVLQKKQWVFVTDGSAQHSGEISNSLLAISFSTSFMDDSSVSHISHNLVGSVVGFCNLIKRAKDVTNEIWVAEAAENSVYFINAEAAYSSHLKTSSAHIQTWAKLSSSKSVIHELRQRVLSIIGACKSPSC rad51_arath DNA repair protein RAD51 homolog 1 RAD51 Rad51-like protein 1 At5g20850 F22D1.20 protein protein arath Arabidopsis thaliana (Mouse-ear cress) Mouse-ear cress MTTMEQRRNQNAVQQQDDEETQHGPFPVEQLQAAGIASVDVKKLRDAGLCTVEGVAYTPRKDLLQIKGISDAKVDKIVEAASKLVPLGFTSASQLHAQRQEIIQITSGSRELDKVLEGGIETGSITELYGEFRSGKTQLCHTLCVTCQLPMDQGGGEGKAMYIDAEGTFRPQRLLQIADRFGLNGADVLENVAYARAYNTDHQSRLLLEAASMMIETRFALLIVDSATALYRTDFSGRGELSARQMHLAKFLRSLQKLADEFGVAVVITNQVVAQVDGSALFAGPQFKPIGGNIMAHATTTRLALRKGRAEERICKVISSPCLPEAEARFQISTEGVTDCKD brc2b_arath Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B BRCA2B BRCA2(V) F7A7.150 At5g01630 protein protein arath Arabidopsis thaliana (Mouse-ear cress) Mouse-ear cress MSTWHLFSDSSGDGFRWEVAGRILQSVSDSTPTKALESTAPLPSMADLLLQGCSKLIEREESMPGEIPMFRTGLGKSVVLKESSIAKAKSILAENVAYSDLQNTNCSIPQTRQVDTAETMPMFRTALGKTVPLKESSIAKPLSILGSDMIIDSDNVLPRESGFGVPNSLFQTASNKKVNVSSAGLARAKALLGLEEDDLNGFNHVNQSSSSLQQHGWSGLKTHEEFDATVVKHHSGTPGQYENYVSGKRSEILNPSLKVPPTKFQTAGGKSLSVSAEALKRARNLLGDPELGSFFDDVAGGDQFFTPQKDERLSDIAINNGSVNTGYIAHEEKTSNKHTSNSFVSPLHSSSKQFRSVNLENLASGGNLIKKFDTAVDETNCALNISKPATHGLSNNRPLASDMAVNNSKGNGFIPRARQLGRPADQPLVDITNRRDTAYANNKQDSTQKKRLGKTVSVSPFKRPRISSFKTPLKKNAQQASSGLSVVSCDTLTSKKVLSTRYPEKSPRVYIKEFFGMHPTATTRMDYVPDHVRRIKSSNADKYVFCDESSSNKVGAETFLQMLAESGASLQHASRKWVTNHYRWIVWKLACYDIYYPAKCRGNFLTITNVLEELKYRYEREVNHGHCSAIKRILSGDAPASSMMVLCISAINPRTDNGSQEAHCSDNCSNVKVELTDGWYSMNAALDVVLTKQLNAGKLFVGQKLRILGAGLSGWATPTSPLEAVISSTICLLLNINGTYRAHWADRLGFCKEIGVPLAFNCIKCNGGPVPKTLAGITRIYPILYKERLGEKKSIVRSERIESRIIQLHNQRRSALVEGIMCEYQRGINGVHSQNDTDSEEGAKVFKLLETAAEPELLMAEMSLEQLTSFTTYKAKFEAAKQMQMEKSVAKALEDAGLGERNVTPFMRIRLVGLTSLSNEGEHNPKEGIVTIWDPTERQRTELTEGKIYIMKGLVPMNSDSETLYLHARGSSSRWQPLSPKDSENFQPFFNPRKPISLSNLGEIPLSSEFDIAAYVVYVGDAYTDVLQKKQWVFVTDGSTQHSGEISNSLLAISFSTPFMDDSSVSHISHNLVGSVVGFCNLIKRAKDATNEMWVAETTENSVYFINAEAAYSSHLKTRSAHIQTWAKLYSSKSVIHELRQRVLFIIGACKSPSC dmc1_arath Meiotic recombination protein DMC1 homolog DMC1 LIM15 F5N5.6 At3g22880 protein protein arath Arabidopsis thaliana (Mouse-ear cress) Mouse-ear cress MMASLKAEETSQMQLVEREENDEDEDLFEMIDKLIAQGINAGDVKKLQEAGIHTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKIVNFGYMTGSDALIKRKSVVKITTGCQALDDLLGGGIETSAITEAFGEFRSGKTQLAHTLCVTTQLPTNMKGGNGKVAYIDTEGTFRPDRIVPIAERFGMDPGAVLDNIIYARAYTYEHQYNLLLGLAAKMSEEPFRILIVDSIIALFRVDFTGRGELADRQQKLAQMLSRLIKIAEEFNVAVYMTNQVIADPGGGMFISDPKKPAGGHVLAHAATIRLLFRKGKGDTRVCKVYDAPNLAEAEASFQITQGGIADAKD f6n15_14-rad51-1 Interaction detected by Y2H 105353 N/A 105355 unspecified role unspecified role bait bait N/A 105356 unspecified role unspecified role prey prey physical association physical association false false false AA 1-784 of Brca2(IV) showed interaction with Rad51. at5g01630-rad51-1 Interaction detected by Y2H 105353 N/A 105357 unspecified role unspecified role bait bait N/A 105356 unspecified role unspecified role prey prey physical association physical association false false false f6n15_14-lim15-1 Interaction detected by Y2H 105353 N/A 105355 unspecified role unspecified role bait bait N/A 105358 unspecified role unspecified role prey prey physical association physical association false false false at5g01630-dmc1-1 Interaction detected by Y2H 105353 N/A 105357 unspecified role unspecified role bait bait N/A 105358 unspecified role unspecified role prey prey physical association physical association false false false rad51-rad51-3 Interaction detected by Y2H 105353 N/A 105356 unspecified role unspecified role bait bait N/A 105356 unspecified role unspecified role prey prey physical association physical association false false false rad51-dmc1-1 Interaction detected by Y2H 105353 N/A 105358 unspecified role unspecified role prey prey N/A 105356 unspecified role unspecified role bait bait physical association physical association false false false lim15-lim15-1 Interaction detected by Y2H 105353 N/A 105358 unspecified role unspecified role bait bait N/A 105358 unspecified role unspecified role prey prey physical association physical association false false false lim15-rad51-1 Interaction detected by Y2H 105353 N/A 105358 unspecified role unspecified role bait bait N/A 105356 unspecified role unspecified role prey prey physical association physical association false false false f6n15_14-rad15 Yeast 2 hybrid analysis reveals interaction between the F6N15.14 protein and RAD15 protein 105354 N/A 105356 unspecified role unspecified role prey prey N/A 105355 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false f6n15_14-dmc1 Yeast 2 hybrid analysis reveals interaction between the F6N15.14 protein and DMC1 protein 105354 N/A 105358 unspecified role unspecified role prey prey N/A 105355 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false brca2b-dmc1-1 Yeast 2 hybrid analysis reveals interaction between the BRCA2b protein and DMC1 protein 105354 N/A 105358 unspecified role unspecified role prey prey n/a 105357 unspecified role unspecified role bait bait physical association physical association false false false brca2b-rad15 Yeast 2 hybrid analysis reveals interaction between the BRCA2b protein and RAD15 protein 105354 n/a 105357 unspecified role unspecified role bait bait N/A 105356 unspecified role unspecified role prey prey physical association physical association false false false