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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="13586">
                <names>
                    <shortLabel>holden-2001-1</shortLabel>
                    <fullName>Cartilage oligomeric matrix protein interacts with type IX collagen, and disruptions to these interactions identify a pathogenetic mechanism in a bone dysplasia family.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="11087755" refType="primary-reference" refTypeAc="MI:0358"/>
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                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-434592" refType="identity" refTypeAc="MI:0356"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Holden P., Meadows RS., Chapman KL., Grant ME., Kadler KE., Briggs MD.</attribute>
                    <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2001</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="13587">
                <names>
                    <shortLabel>q90800_chick</shortLabel>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q90800" version="TrEMBL_44" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_990636.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008160" version="TrEMBL_113"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005581" secondary="collagen trimer" version="TrEMBL_113"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7447242" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-151160" refType="intact-secondary"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9031">
                    <names>
                        <shortLabel>chick</shortLabel>
                        <fullName>Gallus gallus (Chicken)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Chicken</alias>
                    </names>
                </organism>
                <sequence>MTVFPTLGLLFLCQLLATTSAQRVGPQGPPGPRGPPGPSGKDGIDGEPGPSGLPGPPGPKGAPGKPGAAGEAGLPGLPGVDGLTGTDGPPGPNGPPGDRGALGPAGPPGPAGKGLPGPPGPPGPSGLPGGNGFRGPPGPSGLPGFPGPPGPPGPPGLAGIIPEGGGDLQCPALCPPGPPGPPGMPGFKGHTGHKGEPGEIGKEGEKGSPGPPGPPGIPGSVGLQGPRGLRGLPGPMGPAGDRGDIGFRGPPGIPGPPGRAGDQGNKGPQGFRGPKGDTGRPGPKGNPGARGLIGEPGIPGKDGRDGAPGLDGEKGDAARMGVPGEKGPNGLPGLPGRAGIKGSKGEPGSPGEMGEAGPSGEPGIPGDVGIPGDRGLPGPRGATGPVGLPGPIGAPGVRGFQGPKGASGEPGLPGPTGIRGESGDRGPAGVIGAKGSQGIAGADGLPGDKGELGPFGPPGQKGEPGKRGELGPKGAQGPNGTAGAPGIPGHPGPMGHQGEQGVPGITGKPGPPGKEASEQHIRELCGEMINDQIAQLAANLRKPLSPGMTGRPGPAGPPGPPGATGSVGHPGARGPPGYRGPTGELGDPGPRGDTGEKGDKGPAGQGIDGPDGDQGPQGLPGVPGISKNGRDGAQGEPGLPGDPGTPGAVGAQGTPGICDTSACMGAVGASTSKKS</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="13588">
                <names>
                    <shortLabel>comp_bovin</shortLabel>
                    <fullName>Cartilage oligomeric matrix protein</fullName>
                    <alias typeAc="MI:0301" type="gene name">COMP</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P35445" version="SP_84" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097084" secondary="vascular associated smooth muscle cell development" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009306" secondary="protein secretion" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050881" secondary="musculoskeletal movement" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008859" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028974" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024665" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039081" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028492" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002063" secondary="chondrocyte development" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" secondary="regulation of gene expression" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902732" secondary="positive regulation of chondrocyte proliferation" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030509" secondary="BMP signaling pathway" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010259" secondary="multicellular organism aging" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005178" secondary="integrin binding" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014829" secondary="vascular associated smooth muscle contraction" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043395" secondary="heparan sulfate proteoglycan binding" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006986" secondary="response to unfolded protein" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048844" secondary="artery morphogenesis" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003367" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018097" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017897" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003417" secondary="growth plate cartilage development" version="SP_146"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSBTAP00000006074" version="SP_146" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035264" secondary="multicellular organism growth" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008201" secondary="heparin binding" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320" version="SP_146"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSBTAG00000004630" version="SP_146" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070527" secondary="platelet aggregation" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035988" secondary="chondrocyte proliferation" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001881" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060173" secondary="limb development" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005518" secondary="collagen binding" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030282" secondary="bone mineralization" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030199" secondary="collagen fibril organization" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000742" version="SP_146"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010260" secondary="animal organ senescence" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0062023" secondary="collagen-containing extracellular matrix" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035989" secondary="tendon development" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" secondary="protease binding" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036122" secondary="BMP binding" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030500" secondary="regulation of bone mineralization" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900047" secondary="negative regulation of hemostasis" version="SP_146"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSBTAT00000006074" version="SP_146" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016485" secondary="protein processing" version="SP_146"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9913">
                    <names>
                        <shortLabel>bovin</shortLabel>
                        <fullName>Bos taurus (Bovine)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Bovine</alias>
                    </names>
                </organism>
                <sequence>MVLAAARVLLLTLAALGASGQGQMPLGGDLGPQMLRELQETNAALQDVRDLLRQQVKEITFLKNTVMECDACGMQPARTPKLTVRPLSQCSPGFCFPGVACTETANGARCGPCPEGFTGNGSHCADVNECTAHPCFPRVRCINTSPGFRCEACPPGFSGPTHEGVGLAFAKANKQVCTDINECETGQHNCVPNSVCVNTVGSFQCGPCQPGFVGDQASGCRRRPQRFCPDGTPSPCHEKADCVLERDGSRSCVCAVGWAGNGLICGRDTDLDGFPDEKLRCSERQCRKDNCVTVPNSGQEDVDQDGIGDACDPDADGDGVLNEKDNCPLVRNPDQRNTDGDKWGDACDNCRSQKNDDQKDTDKDGRGDACDDDIDGDRIRNPVDNCPKVPNSDQKDTDGDGVGDACDNCPQKSNADQRDVDHDFVGDACDSDQDQDGDGHQDSKDNCPTVPNSAQQDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDMDRDGVGDACQGDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTATDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTASQVRLLWKDPRNVGWKDKTSYRWFLQHRPQVGYIRVRFYEGPELVADSNVILDTTMRGGRLGVFCFSQENIIWANLRYRCNDTIPEDYEAQRLLQA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="13589">
                <names>
                    <shortLabel>comp-q90800</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-18923" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7447239" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>13586</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="13590">
                        <names>
                            <shortLabel>q90800_chick</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-434598" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7447254" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>13587</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="13591">
                        <names>
                            <shortLabel>comp_bovin</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-434594" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7447251" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>13588</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
