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                    <fullName>Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.</fullName>
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                    <fullName>Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.</fullName>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR</sequence>
            </interactor>
            <interactor id="219796">
                <names>
                    <shortLabel>lck_human</shortLabel>
                    <fullName>Tyrosine-protein kinase Lck</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein YT16</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Proto-oncogene Lck</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T cell-specific protein-tyrosine kinase</alias>
                    <alias typeAc="MI:0301" type="gene name">LCK</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Lymphocyte cell-specific protein-tyrosine kinase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p56-LCK</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Leukocyte C-terminal Src kinase</alias>
                </names>
                <xref>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IIM" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001772" secondary="immunological synapse" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3B2W" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051117" secondary="ATPase binding" version="SP_266"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004715" secondary="non-membrane spanning protein tyrosine kinase activity" version="SP_266"/>
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                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001036236.1"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ZYB" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_266"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ACK" version="SP_266"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-389356" version="SP_266"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1KIK" version="SP_266"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004722" secondary="protein serine/threonine phosphatase activity" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006882" secondary="cellular zinc ion homeostasis" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CWE" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031295" secondary="T cell costimulation" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043548" secondary="phosphatidylinositol 3-kinase binding" version="SP_266"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-553N"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4C3F" version="SP_266"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043274" secondary="phospholipase binding" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051249" secondary="regulation of lymphocyte activation" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Q68" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" secondary="cell differentiation" version="SP_266"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2OG8" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Q69" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050862" secondary="positive regulation of T cell receptor signaling pathway" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BRH" version="SP_266"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001452" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ZM4" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1BHF" version="SP_266"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3AC4" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3AC2" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MTM" version="SP_266"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004714" secondary="transmembrane receptor protein tyrosine kinase activity" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903039" secondary="positive regulation of leukocyte cell-cell adhesion" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_266"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3KMM" version="SP_266"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_266"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019903" secondary="protein phosphatase binding" version="SP_266"/>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP</sequence>
            </interactor>
            <interactor id="219797">
                <names>
                    <shortLabel>cd4_human</shortLabel>
                    <fullName>T-cell surface glycoprotein CD4</fullName>
                    <alias typeAc="MI:0301" type="gene name">CD4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">T-cell surface antigen T4/Leu-3</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A7X" version="SP_238"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-617N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4Q6I" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Q68" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1G9N" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042289" secondary="MHC class II protein binding" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6L1Y" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5THR" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NY3" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VN3" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_238"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DUS5" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-353826" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CDI" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030225" secondary="macrophage differentiation" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GC1" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042012" secondary="interleukin-16 receptor activity" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JL4" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007169" secondary="transmembrane receptor protein tyrosine kinase signaling pathway" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CAY" version="SP_238"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-173107" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CDY" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OPT" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4H8W" version="SP_238"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202433" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_238"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NXY" version="SP_238"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="219798">
                <names>
                    <shortLabel>lck-pik3r1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-66003" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650611" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>219793</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="219799">
                        <names>
                            <shortLabel>p85a_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-1512209" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650621" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>219795</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="219800">
                        <names>
                            <shortLabel>lck_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-1512200" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650618" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>219796</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="219801">
                                <names>
                                    <shortLabel>tagged molecule</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-1512204" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650624" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>tag</shortLabel>
                                        <fullName>tag</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="219802">
                                <names>
                                    <shortLabel>binding site</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="interpro" dbAc="MI:0449" id="IPR001452" secondary="SH3" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1512201" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650627" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="62"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="126"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F4</attribute>
                    <attribute name="comment" nameAc="MI:0612">SHORTLABEL=human HBP-ALL T-cells</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction id="219803">
                <names>
                    <shortLabel>cd4-lck-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-66002" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650638" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>219794</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="219804">
                        <names>
                            <shortLabel>lck_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-1512224" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650648" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>219796</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>polyclonal western</shortLabel>
                                    <fullName>polyclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">polyclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="219805">
                        <names>
                            <shortLabel>cd4_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-1512220" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8650645" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>219797</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>monoclonal western</shortLabel>
                                    <fullName>monoclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">monoclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0072" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-955" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F1C</attribute>
                    <attribute name="comment" nameAc="MI:0612">SHORTLABEL=human HBP-ALL T-cells</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
