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    <entry>
        <source releaseDate="2020-09-28+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3730963">
                <names>
                    <shortLabel>kern-2020-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="32587976" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-25816818" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28289" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1101/2020.06.17.156554" refType="see-also" refTypeAc="MI:0361"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="7108">
                        <names>
                            <shortLabel>spofr-sf_9</shortLabel>
                            <fullName>Spodoptera frugiperda insect cells</fullName>
                            <alias typeAc="MI:1041" type="synonym">Fall armyworm</alias>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>sf_9</shortLabel>
                                <fullName>insect cells</fullName>
                            </names>
                            <xref>
                                <primaryRef db="cabri" dbAc="MI:0246" id="ACC 125" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-86941" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-346407" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0078" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                            <attributeList>
                                <attribute name="comment" nameAc="MI:0612">Derived from pupal ovarian tissue of the fall armyworm</attribute>
                                <attribute name="comment" nameAc="MI:0612">Cloned from the parent cell line, IPLB-SF-21-AE (SF-21)</attribute>
                                <attribute name="comment" nameAc="MI:0612">derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae</attribute>
                                <attribute name="comment" nameAc="MI:0612">cells are susceptible to Baculovirus infection</attribute>
                            </attributeList>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>3d-em</shortLabel>
                        <fullName>3D electron microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">3D-EM</alias>
                        <alias typeAc="MI:1041" type="synonym">electron tomog</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0410" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="12160704" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608522" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>structure determination</shortLabel>
                        <fullName>identification by structure determination</fullName>
                        <alias typeAc="MI:1041" type="synonym">identification by structure determination</alias>
                        <alias typeAc="MI:1041" type="synonym">structure determination</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2287" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7877166" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-20597534" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Kern DM., Sorum B., Hoel CM., Sridharan S., Remis JP., Toso DB., Brohawn SG.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">brohawn@berkeley.edu</attribute>
                    <attribute name="curation request" nameAc="MI:0873">by Birgit</attribute>
                    <attribute name="journal" nameAc="MI:0885">bioRxiv : the preprint server for biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2020</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Coronavirus - Interactions investigated in the context of Coronavirus</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3730964">
                <names>
                    <shortLabel>ap3a_sars2</shortLabel>
                    <fullName>ORF3a protein</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Accessory protein 3a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein U274</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein X1</alias>
                    <alias typeAc="MI:0306" type="orf name">3a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein 3a</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P0DTC3" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XDC"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0039707" secondary="pore formation by virus in membrane of host cell" version="SP_9"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044187" secondary="host cell lysosome" version="SP_9"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055036" secondary="virion membrane" version="SP_9"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9694635"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_9"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9694614"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024407"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005216" secondary="ion channel activity" version="SP_9"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0020002" secondary="host cell plasma membrane" version="SP_9"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9694322"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044174" secondary="host cell endosome" version="SP_9"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9694719"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005788" secondary="endoplasmic reticulum lumen" version="SP_9"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_9"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="YP_009724391.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033116" secondary="endoplasmic reticulum-Golgi intermediate compartment membrane" version="SP_9"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7KJR"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-25475894" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="2697049">
                    <names>
                        <shortLabel>SARS-CoV-2</shortLabel>
                        <fullName>SARS-CoV-2</fullName>
                        <alias typeAc="MI:1041" type="synonym">SARS-CoV-2</alias>
                        <alias typeAc="MI:1041" type="synonym">Severe acute respiratory syndrome coronavirus 2</alias>
                        <alias typeAc="MI:1041" type="synonym">2019-nCoV</alias>
                    </names>
                </organism>
                <sequence>MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-28289-1" id="3730965">
                <names>
                    <shortLabel>ap3a_sars2-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="6XDC" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28289-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="emdb" dbAc="MI:0936" id="EMD-22139" refType="see-also" refTypeAc="MI:0361"/>
                    <secondaryRef db="emdb" dbAc="MI:0936" id="EMD-22138" refType="see-also" refTypeAc="MI:0361"/>
                    <secondaryRef db="emdb" dbAc="MI:0936" id="EMD-22136" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-25816826" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3730963</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3730966">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-25816832" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3730964</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="3730967">
                                <names>
                                    <shortLabel>post-cleavage</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-25816833" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>tag</shortLabel>
                                        <fullName>tag</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 2.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table S1</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
