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                <names>
                    <shortLabel>rivera_calz-2007-1</shortLabel>
                    <fullName>Structural model of full-length human Ku70-Ku80 heterodimer and its recognition of DNA and DNA-PKcs.</fullName>
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                        <shortLabel>predetermined</shortLabel>
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                    <attribute name="author-list" nameAc="MI:0636">Rivera-Calzada A., Spagnolo L., Pearl LH., Llorca O.</attribute>
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                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
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                    <shortLabel>riveraca-2007-1</shortLabel>
                    <fullName>Structural model of full-length human Ku70-Ku80 heterodimer and its recognition of DNA and DNA-PKcs.</fullName>
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                            <shortLabel>human-hela</shortLabel>
                            <fullName>Homo sapiens epitheloid cervix carcinoma cells</fullName>
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                                <shortLabel>hela</shortLabel>
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                    <shortLabel>xrcc5_human</shortLabel>
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                    <alias typeAc="MI:0302" type="gene name synonym">ATP-dependent DNA helicase II 80 kDa subunit</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Lupus Ku autoantigen protein p86</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">86 kDa subunit of Ku antigen</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ku86</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ku80</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Thyroid-lupus autoantigen</alias>
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                    <alias typeAc="MI:0302" type="gene name synonym">DNA repair protein XRCC5</alias>
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                    <alias typeAc="MI:0302" type="gene name synonym">ATP-dependent DNA helicase 2 subunit 2</alias>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006302" secondary="double-strand break repair" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JEQ" version="SP_237"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_066964.1"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-357997" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071475" secondary="cellular hyperosmotic salinity response" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ERF" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_237"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036465" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070419" secondary="nonhomologous end joining complex" version="SP_237"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFGTDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQHETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGDGPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLVYVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTTKIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLIEAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRVLVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFEEGGDVDDLLDMI</sequence>
            </interactor>
            <interactor id="575949">
                <names>
                    <shortLabel>xrcc6_human</shortLabel>
                    <fullName>X-ray repair cross-complementing protein 6</fullName>
                    <alias typeAc="MI:0301" type="gene name">XRCC6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">G22P1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ATP-dependent DNA helicase II 70 kDa subunit</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Lupus Ku autoantigen protein p70</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">70 kDa subunit of Ku antigen</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Thyroid-lupus autoantigen</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CTC box-binding factor 75 kDa subunit</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DNA repair protein XRCC6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">X-ray repair complementing defective repair in Chinese hamster cells 6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ATP-dependent DNA helicase 2 subunit 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">5'-deoxyribose-5-phosphate lyase Ku70</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P12956" version="SP_110" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000352257" version="SP_244" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001275906.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006266" secondary="DNA ligation" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071475" secondary="cellular hyperosmotic salinity response" version="SP_244"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UCQ3" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070419" secondary="nonhomologous end joining complex" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003034" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7K1J" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071481" secondary="cellular response to X-ray" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_244"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8456785" refType="intact-secondary"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ERG" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005160" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7K0Y" version="SP_244"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000384257" version="SP_244" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000723" secondary="telomere maintenance" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006164" version="SP_244"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-8429298" refType="intact-secondary"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-164843" version="SP_244"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000196419" version="SP_244" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027388" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ZHE" version="SP_244"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3270619" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042162" secondary="telomeric DNA binding" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071480" secondary="cellular response to gamma radiation" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008094" secondary="ATPase, acting on DNA" version="SP_244"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6FG89" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000405878" version="SP_244" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016787" secondary="hydrolase activity" version="SP_244"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693571" version="SP_244"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B1AHC8" version="SP_180" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097680" secondary="double-strand break repair via classical nonhomologous end joining" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034774" secondary="secretory granule lumen" version="SP_244"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001275905.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003684" secondary="damaged DNA binding" version="SP_244"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000353192" version="SP_244" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RZX" version="SP_244"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000359308" version="SP_244" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000360079" version="SP_244" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7K1N" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" secondary="protein C-terminus binding" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JEY" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016194" version="SP_244"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_244"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-353208" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043564" secondary="Ku70:Ku80 complex" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045860" secondary="positive regulation of protein kinase activity" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AXZ" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006303" secondary="double-strand break repair via nonhomologous end joining" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" secondary="transcription regulator complex" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" secondary="activation of innate immune response" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048660" secondary="regulation of smooth muscle cell proliferation" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ERF" version="SP_244"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2843064" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000783" secondary="nuclear telomere cap complex" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005161" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904813" secondary="ficolin-1-rich granule lumen" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" secondary="RNA binding" version="SP_244"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UCQ2" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7K1K" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006165" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036361" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ZHA" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JJR" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ERH" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045621" secondary="positive regulation of lymphocyte differentiation" version="SP_244"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001460.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JEQ" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032993" secondary="protein-DNA complex" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7LSY" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_244"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24188N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051575" secondary="5'-deoxyribose-5-phosphate lyase activity" version="SP_244"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036465" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006310" secondary="DNA recombination" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003678" secondary="DNA helicase activity" version="SP_244"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1834949" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" secondary="double-stranded DNA binding" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030332" secondary="cyclin binding" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5Y3R" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_244"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P12956" version="SP_244"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007420" secondary="brain development" version="SP_244"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7LT3" version="SP_244"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-11282-1" id="575950">
                <names>
                    <shortLabel>xrcc5-xrcc6</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-4051838" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-11282-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7162081" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>575946</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="575951">
                        <names>
                            <shortLabel>xrcc5_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ku80</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-4051839" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7162092" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>575948</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="575952">
                        <names>
                            <shortLabel>ku70_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ku70</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-4051843" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7162089" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>575949</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F2</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-11282-2" id="575953">
                <names>
                    <shortLabel>xrcc5-xrcc6-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-4051792" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-11282-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7162105" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>575947</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="575954">
                        <names>
                            <shortLabel>ku70_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ku70</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-4051793" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7162116" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>575949</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="575955">
                        <names>
                            <shortLabel>xrcc5_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ku80</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-4051794" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7162113" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>575948</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F1F</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
