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                    <shortLabel>fan-2001a-1</shortLabel>
                    <fullName>Role of direct interaction in BRCA1 inhibition of estrogen receptor activity.</fullName>
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                        <shortLabel>predetermined</shortLabel>
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                    <shortLabel>fan-2001a-2</shortLabel>
                    <fullName>Role of direct interaction in BRCA1 inhibition of estrogen receptor activity.</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">RING finger protein 53</alias>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693616" version="SP_263"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9699150" version="SP_263"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-349905" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000931" secondary="gamma-tubulin large complex" version="SP_263"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8953750" version="SP_263"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JLU" version="SP_263"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006349" secondary="regulation of gene expression by genetic imprinting" version="SP_263"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006633" secondary="fatty acid biosynthetic process" version="SP_263"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q7KYU9" version="SP_122" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046600" secondary="negative regulation of centriole replication" version="SP_263"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OQA" version="SP_263"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PXA" version="SP_263"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051865" secondary="protein autoubiquitination" version="SP_263"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4Y2G" version="SP_263"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K0H" version="SP_263"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY</sequence>
            </interactor>
            <interactor id="1944">
                <names>
                    <shortLabel>esr1_human</shortLabel>
                    <fullName>Estrogen receptor</fullName>
                    <alias typeAc="MI:0301" type="gene name">ESR1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ESR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">NR3A1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Estradiol receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ER-alpha</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Nuclear receptor subfamily 3 group A member 1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P03372" version="SP_136" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5AAV" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FAI" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5689896" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3OS8" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DYB" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2G44" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FQS" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5WGQ" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010863" secondary="positive regulation of phospholipase C activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2P15" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1QKT" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2G5O" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CHZ" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1G50" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PFM" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000387500" version="SP_279" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TLP" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TM1" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VPK" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZN9" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939211" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TM8" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DP0" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MGB" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GTR" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PPS" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001628" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ACC" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048863" secondary="stem cell differentiation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TMV" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TN7" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4XI3" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VGH" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YIN" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DZH" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KRI" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BJ4" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DXK" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043627" secondary="response to estrogen" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013088" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001116212.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T1Z" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JFA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DID" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TMO" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" secondary="DNA-binding transcription factor activity" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071391" secondary="cellular response to estrogen stimulus" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007204" secondary="positive regulation of cytosolic calcium ion concentration" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4TUZ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DZ1" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DF6" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GWR" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DI7" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DMC" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FQT" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DWG" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HKF" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2R6W" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IWC" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011533846.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DKG" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060745" secondary="mammary gland branching involved in pregnancy" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ERE" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PSJ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6C42" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060523" secondary="prostate epithelial cord elongation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TM2" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IUI" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EHJ" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034056" secondary="estrogen response element binding" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000338799" version="SP_279" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HYR" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6D0F" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939256" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024178" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2B1V" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QH6" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DIE" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PIT" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QR9" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DT3" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DKB" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035327" secondary="transcriptionally active chromatin" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KRJ" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DK9" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PP6" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E0W" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MGA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KRA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QA6" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KCC" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035500" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001278159.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DZI" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1R5K" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TMW" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TN8" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048146" secondary="positive regulation of fibroblast proliferation" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5AAU" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TLV" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TM7" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OWC" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HMU" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UUA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VPF" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E15" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TN1" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5W9C" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051000" secondary="positive regulation of nitric-oxide synthase activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SQ0" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TM3" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MG5" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1251985" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TJM" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024736" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZNT" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UFW" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UOM" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8866910" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008584" secondary="male gonad development" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JMM" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HHP" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IOG" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VJ1" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2I0J" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DUH" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KCW" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PET" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000405330" version="SP_279" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IV2" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TL3" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IU7" version="SP_279"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14276" version="SP_136" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZNW" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XQC" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043124" secondary="negative regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006715438.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006338" secondary="chromatin remodeling" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KCD" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GS4" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004879" secondary="nuclear receptor activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DZ3" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1HCQ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KR9" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DMA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7KCA" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903799" secondary="negative regulation of production of miRNAs involved in gene silencing by miRNA" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A52" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KRK" version="SP_279"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Q70" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UU7" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DXE" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SUO" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TMQ" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000405330"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2YJA" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001547" secondary="antral ovarian follicle growth" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FQR" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DWE" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DXR" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XP1" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2POG" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000091831" version="SP_279" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000440973" version="SP_279" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DKE" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" secondary="positive regulation of DNA-binding transcription factor activity" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LLQ" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TML" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MGC" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JF9" version="SP_279"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000443427" version="SP_279" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7KCD" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TMU" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TN6" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_279"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939902" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2AYR" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TLX" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TM9" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060749" secondary="mammary gland alveolus development" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4TV1" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TLO" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JDD" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DZ0" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DMF" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TLF" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001292" version="SP_279"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EI1" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_279"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001723" version="SP_279"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-5965N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VVP" version="SP_279"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060687" secondary="regulation of branching involved in prostate gland morphogenesis" version="SP_279"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016865865.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="1945">
                <names>
                    <shortLabel>brca1-esr1-6</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-13785" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795238" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1941</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1946">
                        <names>
                            <shortLabel>brca1_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">BRCA1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-723393" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795247" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1943</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1947">
                                <names>
                                    <shortLabel>binding site</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-723394" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795251" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>deletion analysis</shortLabel>
                                        <fullName>deletion analysis</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="302"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1948">
                        <names>
                            <shortLabel>esr1_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">ESR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-723398" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795243" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1944</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1949">
                                <names>
                                    <shortLabel>binding site</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-723399" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795255" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>deletion analysis</shortLabel>
                                        <fullName>deletion analysis</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="242"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="420"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction id="1950">
                <names>
                    <shortLabel>brca1-esr1-7</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-13786" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795266" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1942</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1951">
                        <names>
                            <shortLabel>esr1_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">ESR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-723412" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795275" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1944</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1952">
                                <names>
                                    <shortLabel>binding site</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-723413" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795283" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>deletion analysis</shortLabel>
                                        <fullName>deletion analysis</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="242"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="420"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1953">
                        <names>
                            <shortLabel>brca1_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">BRCA1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-723407" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795271" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1943</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1954">
                                <names>
                                    <shortLabel>binding site</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-723408" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7795279" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>deletion analysis</shortLabel>
                                        <fullName>deletion analysis</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="302"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
