<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="11762">
                <names>
                    <shortLabel>chan-1999-1</shortLabel>
                    <fullName>14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="10524633" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-375807" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="10524633" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107358" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/44188" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5211905" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-4">
                        <names>
                            <shortLabel>in vivo</shortLabel>
                            <fullName>in vivo</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>coip</shortLabel>
                        <fullName>coimmunoprecipitation</fullName>
                        <alias typeAc="MI:0303" type="go synonym">co-immunoprecipitation</alias>
                        <alias typeAc="MI:0303" type="go synonym">CoIp</alias>
                        <alias typeAc="MI:0303" type="go synonym">immunoprecipitation</alias>
                        <alias typeAc="MI:0303" type="go synonym">Co-IP</alias>
                        <alias typeAc="MI:1041" type="synonym">co-immunoprecipitation</alias>
                        <alias typeAc="MI:1041" type="synonym">CoIp</alias>
                        <alias typeAc="MI:1041" type="synonym">immunoprecipitation</alias>
                        <alias typeAc="MI:1041" type="synonym">Co-IP</alias>
                        <alias typeAc="MI:1041" type="synonym">coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0019" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-98" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Chan TA., Hermeking H., Lengauer C., Kinzler KW., Vogelstein B.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature (0028-0836)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1999</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="11763">
                <names>
                    <shortLabel>chan-1999-2</shortLabel>
                    <fullName>14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="10524633" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-5206894" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="10524633" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107391" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/44188" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-375807" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5211905" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-hct116</shortLabel>
                            <fullName>Human colon carcinoma HCT116 cells</fullName>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>hct116</shortLabel>
                                <fullName>Human colon carcinoma line HCT116</fullName>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:0153" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-727881" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-7718692" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>fluorescence imaging</shortLabel>
                        <fullName>fluorescence microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">fluorescence imaging</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0416" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608494" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Chan TA., Hermeking H., Lengauer C., Kinzler KW., Vogelstein B.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature (0028-0836)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1999</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="11764">
                <names>
                    <shortLabel>cdk1_human</shortLabel>
                    <fullName>Cyclin-dependent kinase 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">p34 protein kinase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cell division protein kinase 1</alias>
                    <alias typeAc="MI:0301" type="gene name">CDK1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CDC2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cell division control protein 2 homolog</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CDC28A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CDKN1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">P34CDC2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P06493" version="SP_118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GU2" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060045" secondary="positive regulation of cardiac muscle cell proliferation" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004693" secondary="cyclin-dependent protein serine/threonine kinase activity" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090166" secondary="Golgi disassembly" version="SP_259"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008271" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4Y72" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030855" secondary="epithelial cell differentiation" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TWN" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106310" secondary="protein serine kinase activity" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031100" secondary="animal organ regeneration" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8878166" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097472" secondary="cyclin-dependent protein kinase activity" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4419969" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016579" secondary="protein deubiquitination" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006260" secondary="DNA replication" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000226" secondary="microtubule cytoskeleton organization" version="SP_259"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O60764" version="SP_118" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046688" secondary="response to copper ion" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030496" secondary="midbody" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030261" secondary="chromosome condensation" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014075" secondary="response to amine" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905448" secondary="positive regulation of mitochondrial ATP synthesis coupled electron transport" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LQF" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006281" secondary="DNA repair" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380284" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2565942" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072686" secondary="mitotic spindle" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-170145" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3301854" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055015" secondary="ventricular cardiac muscle cell development" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174048" version="SP_259"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-35N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042752" secondary="regulation of circadian rhythm" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018107" secondary="peptidyl-threonine phosphorylation" version="SP_259"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001777.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000086" secondary="G2/M transition of mitotic cell cycle" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804114" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014070" secondary="response to organic cyclic compound" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110056" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048511" secondary="rhythmic process" version="SP_259"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GU6" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69205" version="SP_259"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_259"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005270360.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HQ0" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-75035" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-176412" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-176408" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014823" secondary="response to activity" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000307" secondary="cyclin-dependent protein kinase holoenzyme complex" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804757" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070301" secondary="cellular response to hydrogen peroxide" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" secondary="protein kinase activity" version="SP_259"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-444308" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GU4" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674" secondary="protein serine/threonine kinase activity" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007344" secondary="pronuclear fusion" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LC9" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-162658" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GU3" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_259"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000378699" version="SP_259" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045471" secondary="response to ethanol" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380270" version="SP_259"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203698.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K7C4" version="SP_126" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046686" secondary="response to cadmium ion" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042307" secondary="positive regulation of protein import into nucleus" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005876" secondary="spindle microtubule" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8854518" version="SP_259"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000170312" version="SP_259" refType="gene"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="C9J497" version="SP_143" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070371" secondary="ERK1 and ERK2 cascade" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007098" secondary="centrosome cycle" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0065003" secondary="protein-containing complex assembly" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69273" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4YC3" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-176417" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2995383" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2465910" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014038" secondary="regulation of Schwann cell differentiation" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-113507" version="SP_259"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P06493" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1362300" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2514853" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4YC6" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035173" secondary="histone kinase activity" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097125" secondary="cyclin B1-CDK1 complex" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380320" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045995" secondary="regulation of embryonic development" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008353" secondary="RNA polymerase II CTD heptapeptide repeat kinase activity" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106311" secondary="protein threonine kinase activity" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5689896" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69478" version="SP_259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GU7" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5620912" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5687128" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030332" secondary="cyclin binding" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2980767" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009636" secondary="response to toxic substance" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68875" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045740" secondary="positive regulation of DNA replication" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174184" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001618" secondary="virus receptor activity" version="SP_259"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001307847.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900182" secondary="positive regulation of protein localization to nucleus" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010971" secondary="positive regulation of G2/M transition of mitotic cell cycle" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048678" secondary="response to axon injury" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007569" secondary="cell aging" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2299718" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8852276" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034501" secondary="protein localization to kinetochore" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2500257" version="SP_259"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_259"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380259" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018105" secondary="peptidyl-serine phosphorylation" version="SP_259"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007095" secondary="mitotic G2 DNA damage checkpoint signaling" version="SP_259"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000395284" version="SP_259" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM</sequence>
            </interactor>
            <interactor id="11765">
                <names>
                    <shortLabel>1433s_human</shortLabel>
                    <fullName>14-3-3 protein sigma</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Stratifin</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Epithelial cell marker protein 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HME1</alias>
                    <alias typeAc="MI:0301" type="gene name">SFN</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P31947" version="SP_79" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DAU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TLF" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6NV2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XXC" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YOY" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NFW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QHL" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHR" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y3O" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y40" version="SP_222"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023409" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T0L" version="SP_222"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023410" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SIO" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6S39" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y8E" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LTW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4Y32" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6W0L" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AYF" version="SP_222"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000339276" version="SP_222" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N5T" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YPL" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QIU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NQP" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5F" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YP3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6T5H" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NXT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RK8" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BGQ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RWS" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NV4" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NM3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y3V" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MHR" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RP6" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5X" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RL3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OM0" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SLW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JDD" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHN" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6T80" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BI3" version="SP_222"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037435" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LW1" version="SP_222"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6FH30" version="SP_79" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y8A" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BIQ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RWH" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NJA" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RJL" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OKF" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SP5" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010482" secondary="regulation of epidermal cell division" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FAV" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FI5" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ZCJ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RJZ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FBB" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AZ2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1O" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G8K" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GHP" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N5W" version="SP_222"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96DH0" version="SP_79" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LU1" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NJ6" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OEH" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y3R" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TJM" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NXW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SML" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHS" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RKM" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FBW" version="SP_222"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-476295" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BG3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y3W" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6G" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XWD" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y8D" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QDS" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QZS" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HHP" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AOG" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BDT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TL3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BJL" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046827" secondary="positive regulation of protein export from nucleus" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RKK" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NR7" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RM7" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NIG" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QHM" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YP2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BIY" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SIP" version="SP_222"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804114" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043154" secondary="negative regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BGR" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6S3C" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIC" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3IQU" version="SP_222"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5628897" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G8P" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O57" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6K" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NSV" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NK5" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O3R" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1R" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NYE" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BFW" version="SP_222"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P31947" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G8L" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1S" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045606" secondary="positive regulation of epidermal cell differentiation" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QLI" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NJB" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y3S" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y44" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O3Q" version="SP_222"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-28970316" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003334" secondary="keratinocyte development" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SMM" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BDP" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NIX" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NJ9" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G6X" version="SP_222"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000308" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001836" secondary="release of cytochrome c from mitochondria" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3IQV" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6O" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QDT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BGW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NIF" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4Y3B" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QZR" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FI4" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IEA" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SLV" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y1D" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RL6" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FAW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1N" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6F" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHO" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TWZ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BKH" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6S9Q" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5S" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FR3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G8Q" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QDR" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y3M" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YZ5" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N75" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HKB" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YPY" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RWU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4Y5I" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045296" secondary="cadherin binding" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5A" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NM9" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NRL" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6J" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YWT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5BTV" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MOC" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TM7" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NZG" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051219" secondary="phosphoprotein binding" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6T5F" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SIQ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5O" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O3S" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BDY" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O3A" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIB" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N5R" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006469" secondary="negative regulation of protein kinase activity" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6R5L" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OMA" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FCP" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3O8I" version="SP_222"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1445148" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y18" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RX2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NJ8" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5D" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NYF" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BJF" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O3P" version="SP_222"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000340989" version="SP_222" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1Q" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O59" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NZV" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NM1" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XY5" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SMN" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y1J" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NXY" version="SP_222"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9614399" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JC3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RJQ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YOW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YP8" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TCH" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031424" secondary="keratinization" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHP" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FBY" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YQ2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NZK" version="SP_222"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006133.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111447" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HMT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BGV" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QDU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AXN" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DAT" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NLE" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MHC" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NZ6" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3IQJ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YE9" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SIN" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MY9" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y58" version="SP_222"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6FH51" version="SP_79" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G8I" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OK9" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHQ" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MXO" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NK3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HN2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YLU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y8B" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6I" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NRK" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010839" secondary="negative regulation of keratinocyte proliferation" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SMO" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RWI" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008426" secondary="protein kinase C inhibitor activity" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RKI" version="SP_222"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000340989"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T0M" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TLG" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NXS" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NY4" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AEW" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UX0" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NLA" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5P" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5G" version="SP_222"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5625740" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RM5" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O34" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NWS" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIA" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OEG" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HF3" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O6M" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030307" secondary="positive regulation of cell growth" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RHC" version="SP_222"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-75035" version="SP_222"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036815" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FAU" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061436" secondary="establishment of skin barrier" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008630" secondary="intrinsic apoptotic signaling pathway in response to DNA damage" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RL4" version="SP_222"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29861N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6S40" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SPR" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SLX" version="SP_222"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000079" secondary="regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DHM" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NYG" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HMU" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G8J" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1P" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AZ1" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FL5" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y7T" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BJW" version="SP_222"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000175793" version="SP_222" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5U" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3U9X" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HKF" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SMK" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MYC" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YOX" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O3F" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LU2" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVI" version="SP_222"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O5C" version="SP_222"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQEPQS</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="11766">
                <names>
                    <shortLabel>sfn-cdk1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-15829" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107366" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>11762</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="11767">
                        <names>
                            <shortLabel>cdk1_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-375812" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107375" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>11764</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="11768">
                        <names>
                            <shortLabel>1433s_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-375809" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107372" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>11765</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">domino</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction id="11769">
                <names>
                    <shortLabel>cdk1-sfn</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-15830" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107399" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" refType="go-definition-ref" refTypeAc="MI:0242"/>
                </xref>
                <experimentList>
                    <experimentRef>11763</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="11770">
                        <names>
                            <shortLabel>cdk1_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CDC2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-375800" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107410" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>11764</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>subcellular prep</shortLabel>
                                    <fullName>subcellular preparation</fullName>
                                    <alias typeAc="MI:1041" type="synonym">subcellular prep</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0372" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537724" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="11771">
                        <names>
                            <shortLabel>1433s_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-375795" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7107407" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>11765</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F4C</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">domino</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
