IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ takeuchi-1997-1 SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Takeuchi M., Hata Y., Hirao K., Toyoda A., Irie M., Takai Y. Synapse - Interactions of proteins with an established role in the presynapse. J. Biol. Chem. (0021-9258) 1997 takeuchi-1997-3 SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. in vitro In vitro protein array protein array predetermined predetermined participant predetermined Takeuchi M., Hata Y., Hirao K., Toyoda A., Irie M., Takai Y. Synapse - Interactions of proteins with an established role in the presynapse. J. Biol. Chem. (0021-9258) 1997 takeuchi-1997-2 SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. in vitro In vitro anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Takeuchi M., Hata Y., Hirao K., Toyoda A., Irie M., Takai Y. Synapse - Interactions of proteins with an established role in the presynapse. COS cell extract was used but the authors do not specify which strain. J. Biol. Chem. (0021-9258) 1997 takeuchi-1997-4 SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. imaging technique imaging technique microscopy immunostaining immunostaining Takeuchi M., Hata Y., Hirao K., Toyoda A., Irie M., Takai Y. Synapse - Interactions of proteins with an established role in the presynapse. J. Biol. Chem. (0021-9258) 1997 dlg4_rat Disks large homolog 4 Dlg4 Dlgh4 Postsynaptic density protein 95 Synapse-associated protein 90 Psd95 protein protein rat Rattus norvegicus (Rat) Rat MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL dlgp1_rat Disks large-associated protein 1 Dlgap1 Gkap Guanylate kinase-associated protein SAP90/PSD-95-associated protein 1 PSD-95/SAP90-binding protein 1 protein protein rat Rattus norvegicus (Rat) Rat MKGLSGSRSHHHGITCESACDSLSHHSDHKPYLLSPVDHHPADHPYYTQRNSFQAECVGPFSDPLASSTFPRRHYTSQQELKDESALVPRTLATKANRLPTNLLDQFERQLPLSRDGYHTLQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGASKGGVNGGKASPDGSQTVRYGKRSKSKERRSEPKARSNASNASPTSPSWWSSDDNLDGDMCLYHTPSGVMTMGRCPDRSVSQYFMGAYNTISEQAVKASRSNNDVKCSTCANLPVTLDAPLLKKSAWSSTLTVSRAREVYQKASVNMDQAVVKSEACQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTGVIKLSSAVEVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDMISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGSNAAAVTTTTTIATVTTEDRKKDFKKNRCLSIGIQVDDAEESEKMAESKTSSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCKQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL dlgp2_rat Disks large-associated protein 2 Dlgap2 Dap2 SAP90/PSD-95-associated protein 2 PSD-95/SAP90-binding protein 2 protein protein rat Rattus norvegicus (Rat) Rat MGTAQVLPGILQKHCCILPDRNTESQCTLCGEPEEEEGGDLAQPGLSFPGPAEEDIDQQYSWSPTQHFSEERYSPAPRNMKGLTGSRNQPQLCVGHTCGLSPTDECEHPHDHVRHGPDVRQPYLLSPAESCPMDHHRCSPRSSVHSECMMMPVMLGDHVSSSTFPRMHYSSHYDTRDDCATSHASTKVNRIPANLLDQFEKQLPLHRDGFHTLQYHRASAATEQRNESPGRIRHLVHSVQKLFTKSHSLEGSSKSNINGTKSEGRMDDHHQSHLSKHSKRSKSKERKPESKHKSGMSSWWSSDDNLDSDSTYRTPSVAHRHHMDHIPHCYPEALQSPFGDLSLKTSKSNSDVKCSACEGLALTPDTRYMKRSSWSTLTVSQAKEAYRKSSLNLDKPLVHPEIKPSLQPCHYLQVPQDDWGAYPTGGKEEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPTVALRPEPLLKSIIQRPLGDHQTQSYLQAATEVPVGHSLDPSVNYNSPKFRSRNQSYMRAVSTLSQASCVSQMSEAEVNGQFESVCESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIPVMTPSNMTSTIRSTAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGGLYNSMDSLDSNKAMNLALESAAAQRHAADTQSSSTRSIDKAVLVSKAEELLKSRCSSIGVQDSEFPDHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGFPGHVSMEDKGLQFGSSFQRHSEPSTPTQYGALRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPSLDTVETGRMSPCRRDGSWFLKLLHTETKKMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSVEDVSMKFDELHQLKLNDWKIMESPERKEERKIPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSATERADSIEIYIPEAQTRL dlgp3_rat Disks large-associated protein 3 Dlgap3 SAP90/PSD-95-associated protein 3 PSD-95/SAP90-binding protein 3 Dap3 protein protein rat Rattus norvegicus (Rat) Rat MRGYHGDRGSHPRPARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHLSPEGPLSLSEGPSSVGPEGGPGGVGAGGSSSTFPRMYPGQGPFDTCEDCVGHPQGKGATRLLPTFLDQFEKQLPVQQDGFHTLPYQRGPAGPGPGPGSGAAPEARSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRSSSGGDSYSGPGSGGPPTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQTKATGWWSSDDNLDSDSGFLGGRPPGEPGGPFCLDAPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKALARRFASRRSSSVDTARINCCVPPRIHPRSSIPGYSRSLTTGQLSEEFNQQLEAVCGSVFGELESQAVDALDLPGCFRMRSHSYLRAIQAGCSQDDDCLPLLAAPASVSGRPGSSFNFRKAPPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCSSADGLDGPTMGARTLELAPVPPRASPKPPTLIIKTIPGREELRSLARQRKWRPSIGVQVETISDSDTENRSRREFHSIGVQVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKALQFGRPFQRQASEPQPGPRAPTYSVFRTVHTQGQWAYREGYPLPYEPPATDGSPGPPPVPAPGPGSGRRDSWMERGSRSLPDSGRTSPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSLDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEPKEEKKVPPPIPKKPSRGRGVPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL dlgp4_rat Disks large-associated protein 4 Dlgap4 Sapap4 SAP90/PSD-95-associated protein 4 PSD-95/SAP90-binding protein 4 Dap4 protein protein rat Rattus norvegicus (Rat) Rat MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSMEGTTGKVGGNGGKKGVLEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRSGPASGLMTLGRQPERTQPRYFMHAYNTISGHMLKTTKNTTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRDMDSTAEGPIPCRRMRSGSYIKAMGDEDSDESGGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMPLPSKYPSWEEDYNPISDSLNDSGCISQVFGQASLIPQLFGHDQQVREADLSDQYEAACESACSEAESTAAEALDLSLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGITPGPEAPEPPPKHAALKSEHGTLTSSESHSEAVPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTSHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWMETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGICEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKAAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL dlg1_rat Disks large homolog 1 Dlg1 Synapse-associated protein 97 Dlgh1 protein protein rat Rattus norvegicus (Rat) Rat MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVISIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPGNPWESGSLSSAAVTSESLPGGLSPPVEKYRYQDEEVLPSERISPQVPNEVLGPELVHVSEKSLSEIENVHGFVSHSHISPIKPTEAVPPSSPIVPVTPALPVPAESPVVLPSTPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRKAFRKNHEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKAAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSYLGQTPASPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLRETMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYHEYGCSKGGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTDEQARKTFERAVRLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL dlg3_rat Disks large homolog 3 Dlg3 Dlgh3 Synapse-associated protein 102 PSD-95/SAP90-related protein 1 protein protein rat Rattus norvegicus (Rat) Rat MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPSGGNGASSGYGGYSSQTLPSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKNTPKLNGSGPSWWPECTCTNRDWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVTYPAPPQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL dlg1_drome Disks large 1 tumor suppressor protein dlg1 l(1)dlg1 CG1725 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADFIKSSNLNRNCAYEFNNDASSNQTNQSALNQNPIANNVSAQAQAEALSRTFKSELEEILNQRMRIESDTENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQSQSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITREPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTLLRTTQKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEKNEDGSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLSINYTRPVIILGPLKDRINDDLISEYPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL dlg4-dlgap1-1 Interaction of PSD95 and SAPAP1 shown byYeast two hybrid 134627 N/A 134631 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134632 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 430-724 of P31036 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of P31016 (amino acids 534-724). dlg4-dlgap2-1 Interaction of PSD95 and SAPAP2 shown byYeast two hybrid 134627 N/A 134631 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134633 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 430-724 of P31036 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of P31016 (amino acids 534-724). dlg4-dlgap3-1 Interaction of PSD95 and SAPAP3 shown by Yeast two hybrid 134627 N/A 134631 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134634 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 430-724 of P31036 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of P31016 (amino acids 534-724). dlg4-dlgap4-1 Interaction of PSD95 and SAPAP4 shown by yeast two hybrid 134627 N/A 134631 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134635 unspecified role unspecified role prey prey physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 430-724 of P31036 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of P31016 (amino acids 534-724). dlg1-dlg4-1 Interaction of SAP97 and SAPAP4 shown by yeast two hybrid 134627 N/A 134635 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134636 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 587-910 of Q62696 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62696(amino acids 726-910). dlg1-dlgap3-1 Interaction of SAP97 and SAPAP3 shown by yeast two hybrid 134627 N/A 134636 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134634 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 587-910 of Q62696 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62696(amino acids 726-910). dlg1-dlgap2-1 Interaction of SAP97 and SAPAP2 shown by yeast two hybrid 134627 N/A 134636 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134633 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 587-910 of Q62696 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62696(amino acids 726-910). dlg1-dlgap1-1 Interaction of SAP97 and SAPAP1 shown by yeast two hybrid 134627 N/A 134636 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134632 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 587-910 of Q62696 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62696(amino acids 726-910). dlg3-dlgap1-1 Interaction of PSRP1(SAP102) and SAPAP1 shown by yeast two hybrid 134627 N/A 134632 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134637 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 526-835 of Q62936 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62936 (amino acids 645-835). dlg3-dlgap2-1 Interaction of PSRP1(SAP102) and SAPAP2 shown by yeast two hybrid 134627 N/A 134637 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134633 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 526-835 of Q62936 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62936 (amino acids 645-835). dlg3-dlgap3-1 Interaction of PSRP1(SAP102) and SAPAP3 shown by yeast two hybrid 134627 N/A 134637 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134634 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 526-835 of Q62936 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62936 (amino acids 645-835). dlg3-dlgap4-1 Interaction of PSRP1(SAP102) and SAPAP4 shown by yeast two hybrid 134627 N/A 134637 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134635 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated to occur using both of the following baits:1.Amino acids 526-835 of Q62936 containing the SH3 and guanylate kinase domains.2.The guanylate kinase domain of Q62936 (amino acids 645-835). dlgap1-dlg1-1 Interaction of dlg-A and SAPAP1 shown by Yeast two hybrid 134627 N/A 134632 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134638 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated with both of the following baits:1.Amino acids 601-960 of P31007 containing the SH3 and guanylate kinase domains. 2. The guanylate kinase domain of P31007 (amino acids 770-960) dlgap1-dlgap2-1 Interaction of dlg-A and SAPAP2 shown by Yeast two hybrid 134627 N/A 134638 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134633 unspecified role unspecified role prey prey physical association physical association false false false This interaction was demonstrated with both of the following baits:1.Amino acids 601-960 of P31007 containing the SH3 and guanylate kinase domains. 2. The guanylate kinase domain of P31007 (amino acids 770-960) dlg1-dlgap3-2 Interaction of dlg-A and SAPAP3 shown by Yeast two hybrid 134627 N/A 134638 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134634 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated with both of the following baits:1.Amino acids 601-960 of P31007 containing the SH3 and guanylate kinase domains. 2. The guanylate kinase domain of P31007 (amino acids 770-960) dlg1-dlgap4-1 Interaction of dlg-A and SAPAP4 shown by Yeast two hybrid 134627 N/A 134638 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 134635 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false This interaction was demonstrated with both of the following baits:1.Amino acids 601-960 of P31007 containing the SH3 and guanylate kinase domains. 2. The guanylate kinase domain of P31007 (amino acids 770-960) dlgap1-dlg4-1 interaction of PSD95 abd SAPAP1 by biocore. 134628 N/A 134632 unspecified role unspecified role bait bait ecoli Escherichia coli (strain K12) N/A 134631 unspecified role unspecified role prey prey ecoli Escherichia coli (strain K12) direct interaction direct interaction false false false Bait was GST tagged.Prey was the guanylate kinase domain(amino acids 534-724)of PSD95. Dissociation constant was 2.1x10-7M. dlgap2-dlg4-2 Interaction of PSD95 abd SAPAP2 by biocore. 134628 N/A 134631 unspecified role unspecified role prey prey ecoli Escherichia coli (strain K12) N/A 134633 unspecified role unspecified role bait bait ecoli Escherichia coli (strain K12) direct interaction direct interaction false false false Bait was GST tagged.Prey was the guanylate kinase domain(amino acids 534-724)of PSD95. Dissociation constant was 2.3x10-7M. dlg4-dlgap1-2 in vitro interaction of PSD95 and SAPAP 134629 N/A 134631 unspecified role unspecified role bait bait ecoli Escherichia coli (strain K12) N/A 134632 unspecified role unspecified role prey prey chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey physical association physical association false false false PSD95 was full length and GST tagged. The authors demonstrated that the SH3 and guanylate kinase domains of PSD95 (P31016: amino acids 430-724) are sufficient for this interaction. dlgap1-dlg4-2 Co-localisation of PSD95 and SAPAP1 on 293 cells. 134630 N/A 134632 unspecified role unspecified role neutral component neutral component human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 134631 unspecified role unspecified role neutral component neutral component human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. colocalization colocalization false false false The guanylate kinase domain of PSD95 is sufficient for this interaction. This interaction was shown to take place at the plasma membrane.