IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ figueroa-2001-4 Prenylated Rab acceptor protein is a receptor for prenylated small GTPases. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Figueroa C., Taylor J., Vojtek AB. Synapse - Interactions of proteins with an established role in the presynapse. This experiment relates to a negative interaction. J. Biol. Chem. (0021-9258) 2001 IMEx Only protein-protein interactions imex curation imex curation rap1a_human Ras-related protein Rap-1A GTP-binding protein smg p21A Ras-related protein Krev-1 C21KG G-22K RAP1A KREV1 protein protein human Homo sapiens Human MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL praf1_mouse Prenylated Rab acceptor protein 1 PRA1 family protein 1 Prenylin Rabac1 Pra Pra1 Praf1 protein protein mouse Mus musculus Mouse MAAQKDQQKDAEGEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQMEPADGEELQMEPV rap1a-rabac1-2 169390 N/A 169391 unspecified role unspecified role bait bait P62834:p.Gly12Val mutation mutation certain certain sequence position certain certain certain sequence position certain false N/A 169392 unspecified role unspecified role prey prey physical association physical association false false true The interaction does not occur under these experimental conditions. The mutation from gly-val makes the GTP-bound Ras mutant constitutively active. GTP required for activity.