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                <shortLabel>IntAct</shortLabel>
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                    <shortLabel>russo-1996-1</shortLabel>
                    <fullName>Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.</fullName>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL</sequence>
            </interactor>
            <interactor id="511354">
                <names>
                    <shortLabel>ccna2_human</shortLabel>
                    <fullName>Cyclin-A2</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Cyclin A</alias>
                    <alias typeAc="MI:0301" type="gene name">CCNA2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CCN1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CCNA</alias>
                </names>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-170145" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EOM" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006275" secondary="regulation of DNA replication" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000086" secondary="G2/M transition of mitotic cell cycle" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071392" secondary="cellular response to estradiol stimulus" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WEV" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2UZL" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IW9" version="SP_217"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69656" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097124" secondary="cyclin A2-CDK2 complex" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RIJ" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6P3W" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H26" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WIP" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EOP" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OL1" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WMA" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C5O" version="SP_217"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000274026" version="SP_217" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IW6" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WPA" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Q6G" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016572" secondary="histone phosphorylation" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1E9H" version="SP_217"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-176408" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ATH" version="SP_217"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6LER8" version="SP_79" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7B5L" version="SP_217"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804757" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JST" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4CFV" version="SP_217"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-187577" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H1S" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H24" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GY3" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C5X" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IF1" version="SP_217"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-171319" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_217"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-457097" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68949" version="SP_217"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000307" secondary="cyclin-dependent protein kinase holoenzyme complex" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EOI" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EOR" version="SP_217"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OIU" version="SP_217"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIILEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL</sequence>
            </interactor>
            <interactor id="511355">
                <names>
                    <shortLabel>cdn1b_human</shortLabel>
                    <fullName>Cyclin-dependent kinase inhibitor 1B</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Cyclin-dependent kinase inhibitor p27</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p27Kip1</alias>
                    <alias typeAc="MI:0301" type="gene name">CDKN1B</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">KIP1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P46527" version="SP_86" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559582" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048102" secondary="autophagic cell death" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030544" secondary="Hsp70 protein binding" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2AST" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7B5R" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9634638" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048839" secondary="inner ear development" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045736" secondary="negative regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_224"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33341N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019903" secondary="protein phosphatase binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045786" secondary="negative regulation of cell cycle" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003175" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032355" secondary="response to estradiol" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030332" secondary="cyclin binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001890" secondary="placenta development" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007605" secondary="sensory perception of sound" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046686" secondary="response to cadmium ion" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090398" secondary="cellular senescence" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004860" secondary="protein kinase inhibitor activity" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051087" secondary="chaperone binding" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007219" secondary="Notch signaling pathway" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8849470" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006977" secondary="DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071236" secondary="cellular response to antibiotic" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904706" secondary="negative regulation of vascular associated smooth muscle cell proliferation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071407" secondary="cellular response to organic cyclic compound" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9617828" version="SP_224"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P46527" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7B5M" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559586" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804116" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6P8G" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006813" secondary="potassium ion transport" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043434" secondary="response to peptide hormone" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007507" secondary="heart development" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5674400" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045737" secondary="positive regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000082" secondary="G1/S transition of mitotic cell cycle" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69202" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69563" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904030" secondary="negative regulation of cyclin-dependent protein kinase activity" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000614874" version="SP_224" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007096" secondary="regulation of exit from mitosis" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045930" secondary="negative regulation of mitotic cell cycle" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9607240" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031464" secondary="Cul4A-RING E3 ubiquitin ligase complex" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6P8E" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030308" secondary="negative regulation of cell growth" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902806" secondary="regulation of cell cycle G1/S phase transition" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060770" secondary="negative regulation of epithelial cell proliferation involved in prostate gland development" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033673" secondary="negative regulation of kinase activity" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045732" secondary="positive regulation of protein catabolic process" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902746" secondary="regulation of lens fiber cell differentiation" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000111276" version="SP_224" refType="gene"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-187577" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ATH" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" secondary="regulation of cell cycle" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JSU" version="SP_224"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029843" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000228872" version="SP_224" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UQ3" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043200" secondary="response to amino acid" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000507272" version="SP_224" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5U0H2" version="SP_101" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905179" secondary="negative regulation of cardiac muscle tissue regeneration" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004055.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010942" secondary="positive regulation of cell death" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5625900" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051271" secondary="negative regulation of cellular component movement" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071285" secondary="cellular response to lithium ion" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H27" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_224"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-519280" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7B5L" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6P8F" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9661069" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000079" secondary="regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_224"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16307" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198323" version="SP_224"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BUS6" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004861" secondary="cyclin-dependent protein serine/threonine kinase inhibitor activity" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69656" version="SP_224"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000228872" version="SP_224" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042326" secondary="negative regulation of phosphorylation" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009749" secondary="response to glucose" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69231" version="SP_224"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031116" secondary="positive regulation of microtubule polymerization" version="SP_224"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="511356">
                <names>
                    <shortLabel>ccna2-cdk2-1</shortLabel>
                    <fullName>P27(kip1)/cyclin a/cdk2 complex</fullName>
                </names>
                <xref>
                    <primaryRef db="rcsb pdb" dbAc="MI:0460" id="1JSU" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1026119" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>511352</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="511357">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026126" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>511353</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="511358">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026127" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="298"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="7108">
                                <names>
                                    <shortLabel>spofr</shortLabel>
                                    <fullName>Spodoptera frugiperda (Fall armyworm)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Fall armyworm</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="511359">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026123" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>511354</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="511360">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026124" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="173"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="432"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="511361">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026120" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>511355</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="511362">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026121" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="23"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="106"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="assembly">trimeric, multimeric</attribute>
                    <attribute name="3d-resolution" nameAc="MI:0632">2.3A</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
