IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ sessa-2005-1 Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Sessa F., Mapelli M., Ciferri C., Tarricone C., Areces LB., Schneider TR., Stukenberg PT., Musacchio A. PDBe - Data obtained from the Protein Data Bank Europe Mol. Cell (1097-2765) 2005 incea_xenla Inner centromere protein A incenp-a Mitotic phosphoprotein 130 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MNDAECLSHLLQVCARKTEEFVRTLDSKHMVWLLEIEEEARKMFSSDFNAEPELMPKTPSQKRRRKKRTSILPDENRDPSGRRISRRQSNASWSSSVRRLSVRNQNKANDDSIQEEPAQLKRMTRARAQASIKSTPVLETALPESPSQICQKNAQVKISEQERRSAEQKLIESDFELKTVPEITKDNVSETVNSAVPAVPVTPENKSRAAGKLKIAASSTPEQKAEMVDLTCESPRPANEQQLNLSNQSATPTGSKSDRRSVRRSLVVRKSSSRRASLASQFSLASKRESMTREAVRKSIRQSISQKKAAMEISSTSSQRSYQSSIEMVDDEITIKIRPETVPSETVSEEAPAAESPRRSLRSRAFKKIAISNLPDSEEPPRKVTRQMVAGNAEPTPETTEDAQNIRRKSYKRAVDELSDDERPSEEERSPPRKKTPSPPCPPSKIVRPPPHMKSFLHTVQKNQLLMMTPGSIGKNIIMKSFIKRNTPLKTDPKTEEKERQRLDALRKKEEAELQRKQKIEEGKKRKQEELKVRREERLRKVLQARERVEQLEEEKKKKIEQKFAQIDEKSEKVREDRMAEEKAKKKMTAKKQEEVECRRKQEEEARRLKVKQMEEEERRHQELLQKKREEEELERQKKIAEAKRLAEQERERQLLAEKERLRAEREKERIEKEKALQLQRELERAAQEKEQQRREAEERKKREQQERLEQERLRKEQEAKRLQEEEQRKAKEQAAVAASAPVMNVTVDMQNSPACESYEMTPKSCKVPSVKVNEDNYGMDLNSDDSTDDESQPRKPIPAWASGNLLTQAIRQQYYKPIDVDRMYGTIDSPKLEELFNKSKPRYFKRTSSAVWHSPPLSSNRHHLAVGYGLKY aukba_xenla Aurora kinase B-A aurkb-a airk2-a Aurora/IPL1-related kinase 2-A Serine/threonine-protein kinase 12-A Serine/threonine-protein kinase aurora-B-A protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MSYKENLNPSSYTSKFTTPSSATAAQRVLRKEPYVSTFTTPSDNLLAQRTQLSRITPSASSSVPGRVAVSTEMPSQNTALAEMPKRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVKANSRRVLPPVYQSTQSK loc398457-xl_incenp- Mechanism of aurora-b activation by incenp and inhibition by hesperidin. 515820 N/A 515821 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecoli Escherichia coli (strain K12) Stoichiometry: 2.0 N/A 515822 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) Stoichiometry: 2.0 direct interaction direct interaction false false false dimeric, multimeric working 80.300%, free 77.400% 1.8A