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        <source releaseDate="2006-09-22+01:00">
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                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
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                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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                <names>
                    <shortLabel>armache-2005-1</shortLabel>
                    <fullName>Structures of complete RNA polymerase II and its subcomplex, Rpb4/7.</fullName>
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                            <fullName>In vitro</fullName>
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                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
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                        <shortLabel>predetermined</shortLabel>
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                    <attribute name="author-list" nameAc="MI:0636">Armache KJ., Mitterweger S., Meinhart A., Cramer P.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
                    <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2005</attribute>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060213" secondary="positive regulation of nuclear-transcribed mRNA poly(A) tail shortening" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OQJ" version="SP_194"/>
                    <secondaryRef db="ensemblfungi" id="YDR404C" version="SP_194" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003899" secondary="DNA-directed 5'-3' RNA polymerase activity" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HOU" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BY1" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3I" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5U5Q" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JA8" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-6796648" version="SP_194"/>
                    <secondaryRef db="sgd" dbAc="MI:0484" id="S000002812"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001172" secondary="transcription, RNA-templated" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-76042" version="SP_194"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_010692.3"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3I4M" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y1V" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y14" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FZ5" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2VUM" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3B" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QT1" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BBR" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2R93" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-77075" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3F" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GYM" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-73776" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1PQV" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3J1N" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A93" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022967" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O75" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HOZ" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3D" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GYK" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3M" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BXZ" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FYW" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O73" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2B8K" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031369" secondary="translation initiation factor binding" version="SP_194"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012340" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FKI" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HOX" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OT2" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O4K" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PO2" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JA6" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4V1N" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-674695" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C3E" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-113418" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005665" secondary="RNA polymerase II, core complex" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000932" secondary="P-body" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JA7" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HOV" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-6781823" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BXX" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3L" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3J0K" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045948" secondary="positive regulation of translational initiation" version="SP_194"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6VT36" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C4X" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-73779" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K1F" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VVR" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y1Y" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7O4I" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BY7" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-6782210" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-75955" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5SVA" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BBS" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-72086" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3C" version="SP_194"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-6807505" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GYL" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003727" secondary="single-stranded RNA binding" version="SP_194"/>
                    <secondaryRef db="ensemblfungi" id="YDR404C_mRNA" version="SP_194" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A3J" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6I84" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3H3V" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NT9" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3I4N" version="SP_194"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006366" secondary="transcription by RNA polymerase II" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1WCM" version="SP_194"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y1W" version="SP_194"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="559292">
                    <names>
                        <shortLabel>yeast</shortLabel>
                        <fullName>Saccharomyces cerevisiae</fullName>
                        <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                    </names>
                </organism>
                <sequence>MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI</sequence>
                <attributeList>
                    <attribute name="crc64">44C85603A93CDE67</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="515492">
                <names>
                    <shortLabel>rpb4-rpb7-1</shortLabel>
                    <fullName>Crystal structure of yeast subcomplex of rpb4 and rpb7</fullName>
                </names>
                <xref>
                    <primaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y14" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1041332" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>515489</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="515493">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041336" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>515490</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="515494">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041337" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="35"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="221"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 2.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="515495">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041333" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>515491</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="515496">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041334" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="171"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 2.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="assembly">tetrameric, multimeric</attribute>
                    <attribute name="3d-resolution" nameAc="MI:0632">2.3A</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
