UniProt UniProt http://www.uniprot.org corda-1999-1 Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Corda Y., Schramke V., Longhese MP., Smokvina T., Paciotti V., Brevet V., Gilson E., Geli V. geli@ibsm.cnrs-mrs.fr Nat. Genet. (1061-4036) 1999 Chromatin - Epigenetic interactions resulting in chromatin modulation Only protein-protein interactions imex curation corda-1999-2 Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions. in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Corda Y., Schramke V., Longhese MP., Smokvina T., Paciotti V., Brevet V., Gilson E., Geli V. geli@ibsm.cnrs-mrs.fr Nat. Genet. (1061-4036) 1999 Chromatin - Epigenetic interactions resulting in chromatin modulation Only protein-protein interactions imex curation corda-1999-3 Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Corda Y., Schramke V., Longhese MP., Smokvina T., Paciotti V., Brevet V., Gilson E., Geli V. geli@ibsm.cnrs-mrs.fr Nat. Genet. (1061-4036) 1999 Chromatin - Epigenetic interactions resulting in chromatin modulation Only protein-protein interactions imex curation mec3_yeast DNA damage checkpoint control protein MEC3 MEC3 PIP3 YLR288C L8003.15 PSO9 protein protein yeast Saccharomyces cerevisiae Baker's yeast MKLKLIVNGCEAPDDYKLLRTTINTVASLRKTAILRFNSERLTIISTPKSSLNSSNNGTILRGDTGQLWCTIPHDVFRLYTVISARELNTITMECNCDSLLSVFKRYDRVMNQGSSSNMTIKLQSMPEWNTNNGTLSGGTAGGVDTTSKPNPICALGITFEEIVHTSGPNDAIVMNGGVDEHNGLPTTVGTGNLLASNKVIMHSFKVPVKLLFRAQDTRIQEPMINYIQLMMYKLPPISGEFGSAFHGFIRRVERYSNVNHIHLMGVKKKEHGNEGDDVELKIIVNELDWHLEICWNGPLDSVIQRQEGLTDNPSQNQHIDTDGRQEEGSLPIIEADKPMSSLYTNTRDREMEENIRYDEDLLRIEDSSIADTRGNIYTADTSGDTEFNDISVMVEKAEQESSSTHEVIIRCKDWKVCSKLYAAFEEVVLAISHDESCVFHCSLDRGSLEDSEDVEKPRERGQIIYYIARSKGL 4385CEFA9130FEA3 set1_yeast Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 YTX1 KMT2 COMPASS component SET1 SET domain-containing protein 1 Lysine N-methyltransferase 2 YHR119W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSNYYRRAHASSGSYRQPQEQPQYSRSGHYQYSNGHSHQQYSSQYNQRRRYNHNDGTRRRYNDDRPHSSNNASTRQYYATNNSQSGPYVNKKSDISSRRGMSQSRYSNSNVHNTLASSSGSLPTESALLLQQRPPSVLRYNTDNLKSKFHYFDPIKGEFFNKDKMLSWKATDKEFSETGYYVVKELQDGQFKFKIKHRHPEIKASDPRNENGIMTSGKVATHRKCRNSLILLPRISYDRYSLGPPPSCEIVVYPAQDSTTTNIQDISIKNYFKKYGEISHFEAFNDPNSALPLHVYLIKYASSDGKINDAAKAAFSAVRKHESSGCFIMGFKFEVILNKHSILNNIISKFVEINVKKLQKLQENLKKAKEKEAENEKAKELQGKDITLPKEPKVDTLSHSSGSEKRIPYDLLGVVNNRPVLHVSKIFVAKHRFCVEDFKYKLRGYRCAKFIDHPTGIYIIFNDIAHAQTCSNAESGNLTIMSRSRRIPILIKFHLILPRFQNRTRFNKSSSSSNSTNVPIKYESKEEFIEATAKQILKDLEKTLHVDIKKRLIGPTVFDALDHANFPELLAKRELKEKEKRQQIASKIAEDELKRKEEAKRDFDLFGLYGGYAKSNKRNLKRHNSLALDHTSLKRKKLSNGIKPMAHLLNEETDSKETTPLNDEGITRVSKEHDEEDENMTSSSSEEEEEEAPDKKFKSESEPTTPESDHLHGIKPLVPDQNGSSDVLDASSMYKPTATEIPEPVYPPEEYDLKYSQTLSSMDLQNAIKDEEDMLILKQLLSTYTPTVTPETSAALEYKIWQSRRKVLEEEKASDWQIELNGTLFDSELQPGSSFKAEGFRKIADKLKINYLPHRRRVHQPLNTVNIHNERNEYTPELCQREESSNKEPSDSVPQEVSSSRDNRASNRRFQQDIEAQKAAIGTESELLSLNQLNKRKKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN B7FA5D60F71063FD set1-mec3 507593 N/A 507596 unspecified role unspecified role prey prey region C-terminal region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false N/A 507597 unspecified role unspecified role bait bait region SET domain binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false 1A set1-mec3-1 507594 N/A 507596 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) N/A 507597 unspecified role unspecified role prey prey region SET domain binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) direct interaction direct interaction false false false 1C set1-mec3-2 507595 N/A 507596 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 507597 unspecified role unspecified role prey prey physical association physical association false false false 1E