IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ muratoglu-2003-1 Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Muratoglu S., Georgieva S., Papai G., Scheer E., Enunlu I., Komonyi O., Cserpan I., Lebedeva L., Nabirochkina E., Udvardy A., Tora L., Boros I. Chromatin - Epigenetic interactions resulting in chromatin modulation Beta-Gal activity on x-gal plates was used to determine the strength of interaction. ++ indicated intermediate activity and +++ indicated strong activity. The mapping of dADA3 to dik was done from Flybase records. The Ada2a Rpb4 and Ada2b accessions were from the legend to figure 2. boros@nucleus.szbk.u-szeged.hu Mol. Cell. Biol. (0270-7306) 2003 Only protein-protein interactions imex curation muratoglu-2003-2 Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes. drome Drosophila melanogaster (Fruit fly) Fruit fly anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Muratoglu S., Georgieva S., Papai G., Scheer E., Enunlu I., Komonyi O., Cserpan I., Lebedeva L., Nabirochkina E., Udvardy A., Tora L., Boros I. Chromatin - Epigenetic interactions resulting in chromatin modulation boros@nucleus.szbk.u-szeged.hu Mol. Cell. Biol. (0270-7306) 2003 Only protein-protein interactions imex curation Beta-Gal activity on x-gal plates was used to determine the strength of interaction. ++ indicated intermediate activity and +++ indicated strong activity. The mapping of dADA3 to dik was done from Flybase records. The Ada2a Rpb4 and Ada2b accessions were from the legend to figure 2. muratoglu-2003-3 Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes. drome-embryo drosophilla melanogaster embryo embryo Embryo Defined as the development stage prior to the initiation of tissue differentiation. solution sedimentati cosedimentation in solution solution sedimentati western blot western blot Immuno blot Immuno blot Muratoglu S., Georgieva S., Papai G., Scheer E., Enunlu I., Komonyi O., Cserpan I., Lebedeva L., Nabirochkina E., Udvardy A., Tora L., Boros I. Chromatin - Epigenetic interactions resulting in chromatin modulation Drosophila nuclear extract was centrifuged through a 10 to 30% glycerol gradient. boros@nucleus.szbk.u-szeged.hu Mol. Cell. Biol. (0270-7306) 2003 Only protein-protein interactions imex curation Beta-Gal activity on x-gal plates was used to determine the strength of interaction. ++ indicated intermediate activity and +++ indicated strong activity. The mapping of dADA3 to dik was done from Flybase records. The Ada2a Rpb4 and Ada2b accessions were from the legend to figure 2. muratoglu-2003-4 Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes. drome Drosophila melanogaster (Fruit fly) Fruit fly affinity chrom affinity chromatography technology Affinity purification Affinity purification affinity chrom western blot western blot Immuno blot Immuno blot Muratoglu S., Georgieva S., Papai G., Scheer E., Enunlu I., Komonyi O., Cserpan I., Lebedeva L., Nabirochkina E., Udvardy A., Tora L., Boros I. Chromatin - Epigenetic interactions resulting in chromatin modulation Drosophila nuclear extract was chromatographed on a heparin-ultrogel column. Bound proteins were eluted from the column with stepwise elution using buffers containing 0.1, 0.24, 0.5, and 1 M KCl. boros@nucleus.szbk.u-szeged.hu Mol. Cell. Biol. (0270-7306) 2003 Only protein-protein interactions imex curation Beta-Gal activity on x-gal plates was used to determine the strength of interaction. ++ indicated intermediate activity and +++ indicated strong activity. The mapping of dADA3 to dik was done from Flybase records. The Ada2a Rpb4 and Ada2b accessions were from the legend to figure 2. muratoglu-2003-5 Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes. drome Drosophila melanogaster (Fruit fly) Fruit fly molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column western blot western blot Immuno blot Immuno blot Muratoglu S., Georgieva S., Papai G., Scheer E., Enunlu I., Komonyi O., Cserpan I., Lebedeva L., Nabirochkina E., Udvardy A., Tora L., Boros I. Chromatin - Epigenetic interactions resulting in chromatin modulation Drosophila nuclear extract was chromatographed on a heparin-ultrogel column. Bound proteins were eluted from the column with stepwise elution using buffers containing 0.1, 0.24, 0.5, and 1 M KCl. The two fractions eluted at 0.24 and 0.5 M KCl were further analysed by Superose 6 column chromatography. boros@nucleus.szbk.u-szeged.hu Mol. Cell. Biol. (0270-7306) 2003 Only protein-protein interactions imex curation Beta-Gal activity on x-gal plates was used to determine the strength of interaction. ++ indicated intermediate activity and +++ indicated strong activity. The mapping of dADA3 to dik was done from Flybase records. The Ada2a Rpb4 and Ada2b accessions were from the legend to figure 2. tad2b_drome Transcriptional adapter 2B dADA2b Ada2b CG9638 Ada2S protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MTTIADLFTKYNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVFRGKGAWTAREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNGTIGRATWTPAQSQRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNISLSSEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFFRNRNYAQQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGPYGHGKTDHTHTSNGSHRPPSSSLHSPQPNLRKVEMSSGGEASSNSIAPRNTLHIADPTCSGALLPSKNYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPTNSAKGSQQHLQPLQQHPQLLQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLPQPPGSELLSHNELDLCKKHNITPTTYLSVKTVCLSGAPSLGSPMETSLRKFFIKCGWLSH o76216_drome Histone acetyltransferase Gcn5 Pcaf CG4107 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSGGPSITIKSQPIDGNNTGNAAAQQQQQAANGAATAGASGAAGSAQNPGHGGAASGAGSVPAEGTRQNSLQRIQQRKQKVFNLPVPQKLAKLSMYSACQSEGCRCTGWKTPQENRHRDVESSYCPEFNEECRNTSCRHSLRSHIAHLDNISSSSMNELLGAIIDMENLFMSMQRVEDEDTKKVYQYLFRLLRQCVLTRQQAVIRGPLGDPPFETPCITKAVLSLVFYKYNHLSTPELQTMTEVAKTFLNFLNHYNFESPSTRRGDLTHEDASNYKINYTRWLVFCHVPAFCNSLRQCETSLVFGRTLLRTVFQCVSQQLKKKCISERDRFPEDKRSIITLMPKFLETLRAELLKDDSPIWDTSYRPSNSFVIQQRKRNQEVASVPIGPSAASIGGNKRTSVGEPLHKRIKKEPTDRPSSENLDDLPADVVMRAMKSVSESKTTNKAEILFPVNVSRDENVKAEEQKRAIEFHVVGNSLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIKENQPIGGICFRPFPSQGFTEIVFCAVTMSEQVKGYGTHLMNHLKDYSIQRGIKHLLTFADCDAIGYFKKQGFSKDVKLARPVYAGYIKEYDSATLMHCELHPSIVNTQFIAVIRSQSEILKELIAQRHNEVQKVRPGLTCFKEGLPVIPVESIPGLREIGWKPQNRPARSSRPLEESTDPEKLATSFASVLQSVRQHTTAWPFLRPVTAAEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQTKMRELGLWDK q7ksd8-4 Transcriptional adapter 2A Ada2a Rpb4 dADA2a CG43663 ADA2A-SV1 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSFMNPVDMVDEDAADLQFPKVALLHIFTTLNCLFAVEPLGPQVKRFIHAHQNEHTRNSMVLYNPHTLHRYLEEMEEKTRDQNSSVPSATKDANRCATCRCSLTEPYIKCSECLDTLLCLQCFSRGKEAFSHRNNHAYIIVRDNIQVFADEPHWTARDERILLKTLRTHGYGNWEAVSQALDQRHEPAEVRRHYHDCYFGGIFERLLNLKHARDSYVPERMPYVFKMRSLDPPRHDDIASMQFRLSAGYRCARGDFDTPYDTSAESLLSIMVDHRGRDDDNEASESEFEREVTEELQLGLVRAYNNRLRERQRRYKIMRQHGLIMPNRTVSWISKYVHAFGSDASCMRFLGFMQICPDPIKFDMLLESLRYYRELHSQLHKLYDLREHGVRTLSGAKLYARLSKERQQAQRDYSRLKQTDAFDWQQLVQHYESNRSGDPGPLAINSKLYVMNTRRKASPIEIGDLPGYSKLDDGERKLCSVARLVPQSYLDYKNQLVTEQAKLGYLRLADARRLIKIDVNKTRQIYDFLLEHGHISRPPSYG q9vwz1_drome dAda3 CG7098 Ada3 dik Dmel_CG7098 DADA3 Dmel\CG7098 HL-XIV ADA3 dADA3 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSANLKNIKLAHFSGSLGSGGFGISASSGGAGKLPTNGTGGGKSAPTSTFLDSEVLATPGGVVIPIIRTRDVPKLLPTIAAALQRPADDHLAAEDLDAVQLELEQMLSNVALRTRVLKAEYDSLDKDEKRQDRRKLDRVPGSPPCPASMLNGLLGIGSNSSTSLGSPLGGGGASSSSQSKRKRDEPTGVRKKHSSMTILKQQGVSGGTSKHQAKNSPLVVHTDDSMDYLPTLAAANASGSVLPHHQPLPQLPKMTVPKNDTPNKFWLSVEPYCMPLTNEDLRLIDDLLEQYWGPLVPPVPPLGPHYSTVWAQEDIKALQPGGARIKSNNSSGMLKKAEGMVDESITGPLTQRLVSALMEESLMTLPSEQAAVGEHSNSTTSSSNENTHSHSSSSANAAAAAASGNFRSLAMMKHGVGIEQRLKKTLIENGLIDASEFAAHEDVDEVLMEIKRVTTEISTISQFNSEELKRLRAVASEEIKRIAIKQKLDMVDQEILECYKRMLQYRAKRKGHTIEEKQEILRLTNEQRLLADQLERMQMHLPCIGGSGNSLLEPKM q9vea5-1 DNA-directed RNA polymerase II subunit Rpb4 Rpb4 CG43662 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSFMNPVDMVDEDAADLQFPKEFENAETLLISEVHMLLDHRKRQNESADEEQEFSEVFMKTYAYTDSFRKFKNKETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGRFEDEELRQILDDIGTKRSLQY q95u32_drome Rpb7 Dmel\CG31344 anon-WO0118547.636 Dmel_CG31344 CG6572 CG31344 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MQVDGCTSSSSEIPHPAKRETWISGKMQSSSHSKDGHNAAGASKLLQDHQEPEDYLEHLMKEGSQEGDSGADLELPSWYDEQLFRRGQSYFSTYRFVMNAGMLAGLIAVLAIPSILRVLSCTRQSSTAFTAYRRYVRTIFHTQAWYNHNIADRGSRFWTSIAAVRRAHSRSSHACARQGAGQITQKDLALTQFGFIGFITMGAHRIKLKDQDFLEATTHMWRVLGYLLGIKDEYNICGRNWAESKLRLDIVMRKVYEPALANTGEDFKRMTEALINGLWHINTMLSVNANIFFAKRLACVKGYEYYSFDHENGVAQDPQQKLHYYDMGWWDRFIVSYGLFLVTYLHRYALVRWYLNFRVWLVDIFTYYLPYVAIWKFGPKSAYVRIFRNGGEAQDFALGLKDD q92830-2 Histone acetyltransferase KAT2A GCN5-S KAT2A GCN5 GCN5L2 General control of amino acid synthesis protein 5-like 2 Histone acetyltransferase GCN5 Lysine acetyltransferase 2A STAF97 Histone succinyltransferase KAT2A Histone glutaryltransferase KAT2A protein protein human Homo sapiens Human MGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK kat2a_human Histone acetyltransferase KAT2A Histone acetyltransferase GCN5 STAF97 General control of amino acid synthesis protein 5-like 2 GCN5L2 Lysine acetyltransferase 2A KAT2A GCN5 Histone succinyltransferase KAT2A Histone glutaryltransferase KAT2A protein protein human Homo sapiens Human MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK tad2a_human Transcriptional adapter 2-alpha TADA2A TADA2L Transcriptional adapter 2-like KL04P protein protein human Homo sapiens Human MDRLGPFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFDNYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLMERRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSARTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDSGLSPSIPMASNSGRRSAPPLNLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALLNECNKQGGLRLAQARALIKIDVNKTRKIYDFLIREGYITKG gcn5_yeast Histone acetyltransferase GCN5 YGR252W GCN5 ADA4 SWI9 protein protein yeast Saccharomyces cerevisiae Baker's yeast MVTKHQIEEDHLDGATTDPEVKRVKLENNVEEIQPEQAETNKQEGTDKENKGKFEKETERIGGSEVVTDVEKGIVKFEFDGVEYTFKERPSVVEENEGKIEFRVVNNDNTKENMMVLTGLKNIFQKQLPKMPKEYIARLVYDRSHLSMAVIRKPLTVVGGITYRPFDKREFAEIVFCAISSTEQVRGYGAHLMNHLKDYVRNTSNIKYFLTYADNYAIGYFKKQGFTKEITLDKSIWMGYIKDYEGGTLMQCSMLPRIRYLDAGKILLLQEAALRRKIRTISKSHIVRPGLEQFKDLNNIKPIDPMTIPGLKEAGWTPEMDALAQRPKRGPHDAAIQNILTELQNHAAAWPFLQPVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFNNKVKEIPEYSHLID 3200730DDC7EF70D tafab_drome Transcription initiation factor TFIID subunit 10b Taf10b Taf16 CG3069 Transcription initiation factor TFIID 16 kDa subunit dTAF(II)16 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MVGSNFGIIYHNSAGGASSHGQSSGGGGGGDRDRTTPSSHLSDFMSQLEDYTPLIPDAVTSHYLNMGGFQSDDKRIVRLISLAAQKYMSDIIDDALQHSKARTHMQTTNTPGGSKAKDRKFTLTMEDLQPALADYGINVRKVDYSQ taf9_drome Transcription initiation factor TFIID subunit 9 e(y)1 TAF40 CG6474 Transcription initiation factor TFIID 42 kDa subunit TAFII40 p42 Protein enhancer of yellow 1 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKTIDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEEFEFVTN taf10_drome Transcription initiation factor TFIID subunit 10 Taf10 Transcription initiation factor TFIID 24 kDa subunit dTAF(II)24 CG2859 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MASDGEDISVTPAESVTSATDTEEEDIDSPLMQSELHSDEEQPDVEEVPLTTEESEMDELIKQLEDYSPTIPDALTMHILKTAGFCTVDPKIVRLVSVSAQKFISDIANDALQHCKTRTTNIQHSSGHSSSKDKKNPKDRKYTLAMEDLVPALADHGITMRKPQYFV taf4_drome Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID 110 kDa subunit 110 kDa TBP-associated factor Taf4 TAF110 CG5444 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MNTSQTAAGNRITFTSQPLPNGTISIAGNPGAVISTAQLPNTTTIKTIQAGIGGQHQGLQQVHHVQQQQQSQQQQQQQQQTQSAGQPLLNSMLPAGVVVGMRQQAPSQQQQKNVPTNPLSRVVINSHMAGVRPQSPSITLSTLNTGQTPALLVKTDNGFQLLRVGTTTGPPTVTQTITNTSNNSNTTSTTNHPTTTQIRLQTVPAAASMTNTTATSNIIVNSVASSGYANSSQPPHLTQLNAQAPQLPQITQIQTIPAQQSQQQQVNNVSSAGGTATAVSSTTAATTTQQGNTKEKCRKFLANLIELSTREPKPVEKNVRTLIQELVNANVEPEEFCDRLERLLNASPQPCLIGFLKKSLPLLRQALYTKELVIEGIKPPPQHVLGLAGLSQQLPKIQAQIRPIGPSQTTTIGQTQVRMITPNALGTPRPTIGHTTISKQPPNIRLPTAPRLVNTGGIRTQIPSLQVPGQANIVQIRGPQHAQLQRTGSVQIRATTRPPNSVPTANKLTAVKVGQTQIKAITPSLHPPSLAAISGGPPPTPTLSVLSTLNSASTTTLPIPSLPTVHLPPEALRAREQMQNSLNHNSNHFDAKLVEIKAPSLHPPHMERINASLTPIGAKTMARPPPAINKAIGKKKRDAMEMDAKLNTSSGGAASAANSFFQQSSMSSMYGDDDINDVAAMGGVNLAEESQRILGCTENIGTQIRSCKDEVFLNLPSLQARIRAITSEAGLDEPSQDVAVLISHACQERLKNIVEKLAVIAEHRIDVIKLDPRYEPAKDVRGQIKFLEELDKAEQKRHEELEREMLLRAAKSRSRVEDPEQAKMKARAKEMQRAEMEELRQRDANLTALQAIGPRKKLKLDGETVSSGAGSSGGGVLSSSGSAPTTLRPRIKRVNLRDMLFYMEQEREFCRSSMLFKTYLK tbp_drome TATA-box-binding protein Tbp BTF1 TFIID CG9874 TATA-box factor TATA-binding factor TATA sequence-binding protein Transcription initiation factor TFIID TBP subunit protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MDQMLSPNFSIPSIGTPLHQMEADQQIVANPVYHPPAVSQPDSLMPAPGSSSVQHQQQQQQSDASGGSGLFGHEPSLPLAHKQMQSYQPSASYQQQQQQQQLQSQAPGGGGSTPQSMMQPQTPQSMMAHMMPMSERSVGGSGAGGGGDALSNIHQTMGPSTPMTPATPGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEDDSRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNFSSYEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKKQS taf1_drome Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID 230 kDa subunit TAFII250 TBP-associated factor 230 kDa Taf1 TAF250 CG17603 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MEMESDNSDDEGSIGNGLDLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDLEDAIPASKVEAKLTKDDKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLLGDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTSSQPQLKDERRVKSPEDDVEDPSIADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGPMAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTGCGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDLEELGKNLENMLSNKKTSTQLSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQGRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEMTMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAMGKKKRRVGGDLHCDYLQRHNKTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDKLHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQAYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDDGSRVRIKKEVFDDGDYALQHQQMGQAASQSQIYMVDSSNEPTTLDYQQPPQLDFQQVQEMEQLQHQVMPPMQSEQLQQQQTPQGDNDYAWTF rpb1_drome DNA-directed RNA polymerase II subunit RPB1 RpII215 CG1554 DNA-directed RNA polymerase III largest subunit protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSTPTDSKAPLRQVKRVQFGILSPDEIRRMSVTEGGVQFAETMEGGRPKLGGLMDPRQGVIDRTSRCQTCAGNMTECPGHFGHIDLAKPVFHIGFITKTIKILRCVCFYCSKMLVSPHNPKIKEIVMKSRGQPRKRLAYVYDLCKGKTICEGGEDMDLTKENQQPDPNKKPGHGGCGHYQPSIRRTGLDLTAEWKHQNEDSQEKKIVVSAERVWEILKHITDEECFILGMDPKYARPDWMIVTVLPVPPLAVRPAVVMFGAAKNQDDLTHKLSDIIKANNELRKNEASGAAAHVIQENIKMLQFHVATLVDNDMPGMPRAMQKSGKPLKAIKARLKGKEGRIRGNLMGKRVDFSARTVITPDPNLRIDQVGVPRSIAQNLTFPELVTPFNIDRMQELVRRGNSQYPGAKYIVRDNGERIDLRFHPKSSDLHLQCGYKVERHLRDDDLVIFNRQPTLHKMSMMGHRVKVLPWSTFRMNLSCTSPYNADFDGDEMNLHVPQSMETRAEVENIHITPRQIITPQANKPVMGIVQDTLTAVRKMTKRDVFITREQVMNLLMFLPTWDAKMPQPCILKPRPLWTGKQIFSLIIPGNVNMIRTHSTHPDEEDEGPYKWISPGDTKVMVEHGELIMGILCKKSLGTSAGSLLHICFLELGHDIAGRFYGNIQTVINNWLLFEGHSIGIGDTIADPQTYNEIQQAIKKAKDDVINVIQKAHNMELEPTPGNTLRQTFENKVNRILNDARDKTGGSAKKSLTEYNNLKAMVVSGSKGSNINISQVIACVGQQNVEGKRIPYGFRKRTLPHFIKDDYGPESRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRRLIKAMESVMVNYDGTVRNSVGQLIQLRYGEDGLCGELVEFQNMPTVKLSNKSFEKRFKFDWSNERLMKKVFTDDVIKEMTDSSEAIQELEAEWDRLVSDRDSLRQIFPNGESKVVLPCNLQRMIWNVQKIFHINKRLPTDLSPIRVIKGVKTLLERCVIVTGNDRISKQANENATLLFQCLIRSTLCTKYVSEEFRLSTEAFEWLVGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTAIYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEKINVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLSDMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDPIRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAITRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLLLDAEKCRFGIEIPNTLGNSMLGGAAMFIGGGSTPSMTPPMTPWANCNTPRYFSPPGHVSAMTPGGPSFSPSAASDASGMSPSWSPAHPGSSPSSPGPSMSPYFPASPSVSPSYSPTSPNYTASSPGGASPNYSPSSPNYSPTSPLYASPRYASTTPNFNPQSTGYSPSSSGYSPTSPVYSPTVQFQSSPSFAGSGSNIYSPGNAYSPSSSNYSPNSPSYSPTSPSYSPSSPSYSPTSPCYSPTSPSYSPTSPNYTPVTPSYSPTSPNYSASPQYSPASPAYSQTGVKYSPTSPTYSPPSPSYDGSPGSPQYTPGSPQYSPASPKYSPTSPLYSPSSPQHSPSNQYSPTGSTYSATSPRYSPNMSIYSPSSTKYSPTSPTYTPTARNYSPTSPMYSPTAPSHYSPTSPAYSPSSPTFEESED ada2b-pcaf 594658 N/A 594663 unspecified role unspecified role prey prey N/A 594664 unspecified role unspecified role bait bait physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. ++ Table 2 ++ ada2a-pcaf 594658 N/A 594665 unspecified role unspecified role prey prey N/A 594664 unspecified role unspecified role bait bait physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. ++ Table 2 ++ dik-ada2b 594658 N/A 594666 unspecified role unspecified role prey prey N/A 594663 unspecified role unspecified role bait bait physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. +++ Table 2 +++ rpb4-rpb7 594658 N/A 594667 unspecified role unspecified role bait bait N/A 594668 unspecified role unspecified role prey prey physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. ++ Table 2 ++ ada2b-gcn5 594658 N/A 594669 unspecified role unspecified role bait bait N/A 594670 unspecified role unspecified role prey prey physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. +++ Table 2 +++ ada2a-gcn5 594658 N/A 594665 unspecified role unspecified role bait bait N/A 594669 unspecified role unspecified role prey prey physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. +++ Table 2 +++ ada2l-gcn5 594658 n/a 594671 unspecified role unspecified role bait bait N/A 594669 unspecified role unspecified role prey prey physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. +++ Table 2 +++ ada2a-gcn5-2 594658 N/A 594665 unspecified role unspecified role bait bait N/A 594672 unspecified role unspecified role prey prey physical association physical association false false false author score author-based confidence author score A score generated by an author, usually only relevant for that particular dataset. +++ Table 2 +++ taf10-gcn5 594659 N/A 594673 unspecified role unspecified role prey prey N/A 594663 unspecified role unspecified role prey prey N/A 594674 unspecified role unspecified role prey prey N/A 594675 unspecified role unspecified role bait bait N/A 594676 unspecified role unspecified role prey prey N/A 594677 unspecified role unspecified role prey prey N/A 594664 unspecified role unspecified role prey prey association association false false false 4A taf10b-tbp 594659 N/A 594676 unspecified role unspecified role prey prey N/A 594674 unspecified role unspecified role prey prey N/A 594675 unspecified role unspecified role prey prey N/A 594673 unspecified role unspecified role bait bait N/A 594677 unspecified role unspecified role prey prey association association false false false 4A ada2a-gcn5-3 594659 N/A 594665 unspecified role unspecified role bait bait N/A 594663 unspecified role unspecified role prey prey N/A 594674 unspecified role unspecified role prey prey N/A 594677 unspecified role unspecified role prey prey N/A 594664 unspecified role unspecified role prey prey association association false false false 4A ada2b-gcn5-1 594659 N/A 594674 unspecified role unspecified role prey prey N/A 594675 unspecified role unspecified role prey prey N/A 594676 unspecified role unspecified role prey prey N/A 594664 unspecified role unspecified role prey prey N/A 594663 unspecified role unspecified role bait bait N/A 594677 unspecified role unspecified role prey prey association association false false false 4A ada2a-ada2b 594660 N/A 594665 unspecified role unspecified role neutral component neutral component N/A 594678 unspecified role unspecified role neutral component neutral component N/A 594674 unspecified role unspecified role neutral component neutral component N/A 594664 unspecified role unspecified role neutral component neutral component N/A 594663 unspecified role unspecified role neutral component neutral component N/A 594677 unspecified role unspecified role neutral component neutral component N/A 594675 unspecified role unspecified role neutral component neutral component physical association physical association false false false 4B 400 - 800 kDa gcn5-ada2b-2 594660 N/A 594674 unspecified role unspecified role neutral component neutral component N/A 594676 unspecified role unspecified role neutral component neutral component N/A 594678 unspecified role unspecified role neutral component neutral component N/A 594664 unspecified role unspecified role neutral component neutral component N/A 594663 unspecified role unspecified role neutral component neutral component N/A 594677 unspecified role unspecified role neutral component neutral component N/A 594675 unspecified role unspecified role neutral component neutral component physical association physical association false false false 4B Complex size was higher than 2 MDa. ada2a-tbp 594661 N/A 594665 unspecified role unspecified role neutral component neutral component N/A 594673 unspecified role unspecified role neutral component neutral component N/A 594674 unspecified role unspecified role neutral component neutral component N/A 594664 unspecified role unspecified role neutral component neutral component N/A 594677 unspecified role unspecified role neutral component neutral component association association false false false 5A, B ada2b-tbp 594661 N/A 594663 unspecified role unspecified role neutral component neutral component N/A 594678 unspecified role unspecified role neutral component neutral component N/A 594675 unspecified role unspecified role neutral component neutral component N/A 594673 unspecified role unspecified role neutral component neutral component N/A 594676 unspecified role unspecified role neutral component neutral component N/A 594664 unspecified role unspecified role neutral component neutral component N/A 594677 unspecified role unspecified role neutral component neutral component N/A 594674 unspecified role unspecified role neutral component neutral component association association false false false 5A, B gcn5-ada2a-2 594662 N/A 594665 unspecified role unspecified role neutral component neutral component N/A 594664 unspecified role unspecified role neutral component neutral component physical association physical association false false false 5C Complex size between 0.2 and 0.7 MDa Complex was a further elution from a 0.24M KCl fraction of Heparin-UG column. gcn5-ada2b-3 594662 N/A 594676 unspecified role unspecified role neutral component neutral component N/A 594679 unspecified role unspecified role neutral component neutral component N/A 594663 unspecified role unspecified role neutral component neutral component N/A 594674 unspecified role unspecified role neutral component neutral component N/A 594664 unspecified role unspecified role neutral component neutral component physical association physical association false false false 5D Complex size higher than 2 MDa Complex was a further elution from a 0.5M KCl fraction of Heparin-UG column.