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                <shortLabel>bhf-ucl</shortLabel>
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            <experimentDescription id="1476922">
                <names>
                    <shortLabel>tanaka-1998-1</shortLabel>
                    <fullName>A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.</fullName>
                </names>
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                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-kyse150</shortLabel>
                            <fullName>Homo sapiens</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>human-kyse150</shortLabel>
                                <fullName>human-kyse150 esophageal carcinoma</fullName>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
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                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Tanaka S., Akiyoshi T., Mori M., Wands J.R., Sugimachi K.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">shinji@tsurumi.beppu.kyushu-u.ac.jp.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">shinji@tsurumi.beppu.kyushu-u.ac.jp</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proc. Natl. Acad. Sci. U.S.A. (0027-8424)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1998</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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                    <attribute name="imex curation" nameAc="MI:0959"/>
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                    <shortLabel>apc_human</shortLabel>
                    <fullName>Adenomatous polyposis coli protein</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">DP2.5</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Deleted in polyposis 2.5</alias>
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                    </names>
                </organism>
                <sequence>MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV</sequence>
            </interactor>
            <interactor id="1476924">
                <names>
                    <shortLabel>ctnb1_human</shortLabel>
                    <fullName>Catenin beta-1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Beta-catenin</alias>
                    <alias typeAc="MI:0306" type="orf name">OK/SW-cl.35</alias>
                    <alias typeAc="MI:0306" type="orf name">PRO2286</alias>
                    <alias typeAc="MI:0301" type="gene name">CTNNB1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CTNNB</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P35222" version="SP_106" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AR4" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046332" secondary="SMAD binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034394" secondary="protein localization to cell surface" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000791" secondary="euchromatin" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048643" secondary="positive regulation of skeletal muscle tissue development" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001711" secondary="endodermal cell fate commitment" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072053" secondary="renal inner medulla development" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2GL7" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035050" secondary="embryonic heart tube development" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060066" secondary="oviduct development" version="SP_252"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K1L7" version="SP_129" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060789" secondary="hair follicle placode formation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003713" secondary="transcription coactivator activity" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3769402" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000496385" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-195253" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061549" secondary="sympathetic ganglion development" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495719" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000643992" version="SP_252" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" secondary="DNA-binding transcription factor binding" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495360" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" secondary="protein C-terminus binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005911" secondary="cell-cell junction" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005925" secondary="focal adhesion" version="SP_252"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-491563" refType="intact-secondary"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8951430" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032993" secondary="protein-DNA complex" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032212" secondary="positive regulation of telomere maintenance via telomerase" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060742" secondary="epithelial cell differentiation involved in prostate gland development" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002053" secondary="positive regulation of mesenchymal cell proliferation" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000643031" version="SP_252" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000401599" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045177" secondary="apical part of cell" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048599" secondary="oocyte development" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042733" secondary="embryonic digit morphogenesis" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4411364" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358752" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030539" secondary="male genitalia development" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048538" secondary="thymus development" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000496021" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000209" secondary="protein polyubiquitination" version="SP_252"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-122N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000493533" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033234" secondary="negative regulation of protein sumoylation" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SLA" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030997" secondary="regulation of centriole-centriole cohesion" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032968" secondary="positive regulation of transcription elongation from RNA polymerase II promoter" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036023" secondary="embryonic skeletal limb joint morphogenesis" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990909" secondary="Wnt signalosome" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" secondary="transcription factor binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098609" secondary="cell-cell adhesion" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FQR" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000441708" version="SP_252" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031641" secondary="regulation of myelination" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016600" secondary="flotillin complex" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5339716" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019900" secondary="kinase binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050808" secondary="synapse organization" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060070" secondary="canonical Wnt signaling pathway" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000904" secondary="cell morphogenesis involved in differentiation" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M91" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042129" secondary="regulation of T cell proliferation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099092" secondary="postsynaptic density, intracellular component" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097091" secondary="synaptic vesicle clustering" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" secondary="transcription regulator complex" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" secondary="positive regulation of DNA-binding transcription factor activity" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WLX" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051973" secondary="positive regulation of telomerase activity" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8876493" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-201681" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000493610" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495076" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045743" secondary="positive regulation of fibroblast growth factor receptor signaling pathway" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-525793" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000379486" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098831" secondary="presynaptic active zone cytoplasmic component" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DIW" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5218920" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044336" secondary="canonical Wnt signaling pathway involved in negative regulation of apoptotic process" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6O9B" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051884" secondary="regulation of timing of anagen" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000349496" version="SP_252" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061550" secondary="cranial ganglion development" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3TX7" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061324" secondary="canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5358747" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000494914" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" secondary="beta-catenin binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030054" secondary="cell junction" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044338" secondary="canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001221" secondary="transcription coregulator binding" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000645320" version="SP_252" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045765" secondary="regulation of angiogenesis" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071363" secondary="cellular response to growth factor stimulus" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050767" secondary="regulation of neurogenesis" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061198" secondary="fungiform papilla formation" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495244" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-381771" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035112" secondary="genitalia morphogenesis" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-196299" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LUJ" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1TH1" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001837" secondary="epithelial to mesenchymal transition" version="SP_252"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000225" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000643977" version="SP_252" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045296" secondary="cadherin binding" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M94" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001764" secondary="neuron migration" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000494411" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990791" secondary="dorsal root ganglion development" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000405570" version="SP_252" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AFW" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005923" secondary="bicellular tight junction" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000494845" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045294" secondary="alpha-catenin binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045976" secondary="negative regulation of mitotic cell cycle, embryonic" version="SP_252"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016024" version="SP_252"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-491549" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005264943.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495992" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007398" secondary="ectoderm development" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1G3J" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000396185" version="SP_252" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000646369" version="SP_252" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035315" secondary="hair cell differentiation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090279" secondary="regulation of calcium ion import" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JPW" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000168036" version="SP_252" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000496180" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042475" secondary="odontogenesis of dentin-containing tooth" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000494053" version="SP_252" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904798" secondary="positive regulation of core promoter binding" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030316" secondary="osteoclast differentiation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035116" secondary="embryonic hindlimb morphogenesis" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043161" secondary="proteasome-mediated ubiquitin-dependent protein catabolic process" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6O9C" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051571" secondary="positive regulation of histone H3-K4 methylation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060492" secondary="lung induction" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045211" secondary="postsynaptic membrane" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009954" secondary="proximal/distal pattern formation" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010909" secondary="positive regulation of heparan sulfate proteoglycan biosynthetic process" version="SP_252"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000644867" version="SP_252" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-201722" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001658" secondary="branching involved in ureteric bud morphogenesis" version="SP_252"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4641262" version="SP_252"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048660" secondary="regulation of smooth muscle cell proliferation" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M90" version="SP_252"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2G57" version="SP_252"/>
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                        <fullName>protein</fullName>
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                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
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                                <fullName>unspecified role</fullName>
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                                    <fullName>prey</fullName>
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                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
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                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig. 4B</attribute>
                    <attribute name="antagonist" nameAc="MI:0626">human FzE3DeltaC, a mutant form of FzE3 (O75084) lacking the extracellular domain.</attribute>
                    <attribute name="agonist" nameAc="MI:0625">humanFzE3: O75084</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
