Molecular Connections Molecular Connections Pvt. Ltd. 2/2, Kariappa Road, Basavanagudi, Bangalore -560 004 www.molecularconnections.com www.molecularconnections.com el_haibi-2013-1 Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5. human-c4-2b human prostate cells derived from lncap c4-2b human prostate cells derived from lncap prostate_carcinoma Prostate carcinoma (cancer) anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot El-Haibi C.P., Sharma P., Singh R., Gupta P., Taub D.D., Singh S., Lillard J.W. Cancer - Interactions investigated in the context of cancer jlillard@msm.e du jlillard@msm.edu Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. el_haibi-2013-3 Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5. human-pc3 Human PC3 Caucasian prostate adenocarcinoma pc3 Human Caucasian prostate adenocarcinoma anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot El-Haibi C.P., Sharma P., Singh R., Gupta P., Taub D.D., Singh S., Lillard J.W. Cancer - Interactions investigated in the context of cancer jlillard@msm.e du jlillard@msm.edu Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. el_haibi-2013-2 Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5. human-lncap Human caucasian prostate carcinoma lncap Human caucasian prostate adenocarcinoma anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot El-Haibi C.P., Sharma P., Singh R., Gupta P., Taub D.D., Singh S., Lillard J.W. Cancer - Interactions investigated in the context of cancer jlillard@msm.e du jlillard@msm.edu Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. cxcr4_human C-X-C chemokine receptor type 4 Stromal cell-derived factor 1 receptor Fusin Leukocyte-derived seven transmembrane domain receptor LCR1 FB22 NPYRL HM89 CXCR4 Lipopolysaccharide-associated protein 3 protein protein human Homo sapiens Human MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS cxcr5_human C-X-C chemokine receptor type 5 CXCR5 BLR1 MDR15 Burkitt lymphoma receptor 1 Monocyte-derived receptor 15 protein protein human Homo sapiens Human MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF gnai2_human Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 GNAI2B Adenylate cyclase-inhibiting G alpha protein protein protein human Homo sapiens Human MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF gna13_human Guanine nucleotide-binding protein subunit alpha-13 GNA13 protein protein human Homo sapiens Human MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ gbb3_human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GNB3 Transducin beta chain 3 protein protein human Homo sapiens Human MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN gbg8_human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 GNG9 GNGT9 Gamma-9 protein protein human Homo sapiens Human MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCVLL par1_human Proteinase-activated receptor 1 CF2R PAR1 TR Coagulation factor II receptor Thrombin receptor F2R protein protein human Homo sapiens Human MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT cxcr5-cxcr4-1 1474834 n/a 1474837 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait physical association physical association false false false 2b cxcr5-gnai2-2 1474834 n/a 1474838 unspecified role unspecified role bait bait n/a 1474839 unspecified role unspecified role prey prey physical association physical association false false false 2c cxcl13 cxcr5-gna13 1474834 n/a 1474838 unspecified role unspecified role bait bait n/a 1474840 unspecified role unspecified role prey prey physical association physical association false false false 2c cxcl13 cxcr5-gnb3 1474834 n/a 1474838 unspecified role unspecified role bait bait n/a 1474841 unspecified role unspecified role prey prey physical association physical association false false false 2d cxcl13 cxcr5-gng8 1474834 n/a 1474842 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait physical association physical association false false false 2d cxcl13 gnai2-cxcr5-1 1474834 n/a 1474839 unspecified role unspecified role bait bait n/a 1474838 unspecified role unspecified role prey prey physical association physical association false false false 3b cxcl13 gna13-cxcr4 1474834 n/a 1474840 unspecified role unspecified role bait bait n/a 1474837 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role prey prey physical association physical association false false false 3c cxcl13 gna13-cxcr5 1474834 n/a 1474843 unspecified role unspecified role prey prey n/a 1474840 unspecified role unspecified role bait bait n/a 1474838 unspecified role unspecified role prey prey physical association physical association false false false 4a cxcl13 cxcr5-cxcr4 1474835 n/a 1474838 unspecified role unspecified role bait bait n/a 1474837 unspecified role unspecified role prey prey physical association physical association false false false 2b cxcr5-gnai2-3 1474835 n/a 1474839 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait physical association physical association false false false cxcl13 2c cxcr5-gna13-2 1474835 n/a 1474840 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait physical association physical association false false false 2c cxcl13 cxcr5-gnb3-4 1474835 n/a 1474841 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait n/a 1474842 unspecified role unspecified role prey prey physical association physical association false false false 2d cxcl13 gnai2-cxcr5-2 1474835 n/a 1474838 unspecified role unspecified role prey prey n/a 1474839 unspecified role unspecified role bait bait physical association physical association false false false 3b cxcl13 gna13-cxcr4-2 1474835 n/a 1474838 unspecified role unspecified role prey prey n/a 1474837 unspecified role unspecified role prey prey n/a 1474840 unspecified role unspecified role bait bait physical association physical association false false false 3c cxcl13 gna13-cxcr5-2 1474835 n/a 1474840 unspecified role unspecified role bait bait n/a 1474843 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role prey prey physical association physical association false false false 4a cxcl13 cxcr4-cxcr5 1474836 n/a 1474838 unspecified role unspecified role bait bait n/a 1474837 unspecified role unspecified role prey prey physical association physical association false false false 2b cxcr5-gna13-1 1474836 n/a 1474840 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait physical association physical association false false false 2c cxcl13 Interaction of cxcr5 with gnaq/gna11 has not been entered due to lack of antibody specificity. cxcr5-gnb3-3 1474836 n/a 1474842 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role bait bait n/a 1474841 unspecified role unspecified role prey prey physical association physical association false false false 2d cxcl13 gna13-cxcr4-1 1474836 n/a 1474840 unspecified role unspecified role bait bait n/a 1474837 unspecified role unspecified role prey prey n/a 1474838 unspecified role unspecified role prey prey physical association physical association false false false 3c cxcl13 gna13-cxcr5-1 1474836 n/a 1474843 unspecified role unspecified role prey prey n/a 1474840 unspecified role unspecified role bait bait n/a 1474838 unspecified role unspecified role prey prey physical association physical association false false false 4a cxcl13