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    <entry>
        <source releaseDate="2011-02-22Z">
            <names>
                <shortLabel>Molecular Connections</shortLabel>
                <fullName>Molecular Connections Pvt. Ltd.</fullName>
            </names>
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            <attributeList>
                <attribute name="postal address">2/2, Kariappa Road, Basavanagudi, Bangalore -560 004</attribute>
                <attribute name="url" nameAc="MI:0614">www.molecularconnections.com</attribute>
                <attribute name="url">www.molecularconnections.com</attribute>
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        <experimentList>
            <experimentDescription id="1012026">
                <names>
                    <shortLabel>yin-2010-1</shortLabel>
                    <fullName>A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis.</fullName>
                </names>
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                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-endothelium</shortLabel>
                            <fullName>Homo sapiens endothelail cells/endothelium</fullName>
                        </names>
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                            <names>
                                <shortLabel>endothelium</shortLabel>
                                <fullName>Endothelial cells [endothelium]</fullName>
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                        <shortLabel>pla</shortLabel>
                        <fullName>proximity ligation assay</fullName>
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                    <names>
                        <shortLabel>antibody detection</shortLabel>
                        <fullName>identification by antibody</fullName>
                        <alias typeAc="MI:1041" type="synonym">antibody detection</alias>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Yin X., Truty J., Lawrence R., Johns SC., Srinivasan RS., Handel TM., Fuster MM.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Cancer - Interactions investigated in the context of cancer</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">hLEC: Primary human lymphatic endothelial cells</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">mfuster@ucsd.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Mol. Cancer (null)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="external curation">Curation by: Molecular Connections Pvt. Ltd</attribute>
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            <interactor id="1012027">
                <names>
                    <shortLabel>ccr7_human</shortLabel>
                    <fullName>C-C chemokine receptor type 7</fullName>
                    <alias typeAc="MI:0301" type="gene name">CCR7</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CMKBR7</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">EBI1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">EVI1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">BLR2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CDw197</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Epstein-Barr virus-induced G-protein coupled receptor 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MIP-3 beta receptor</alias>
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                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
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                <sequence>MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP</sequence>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418594" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097026" secondary="dendritic cell dendrite assembly" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090630" secondary="activation of GTPase activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031295" secondary="T cell costimulation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035759" secondary="mesangial cell-matrix adhesion" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" secondary="cellular response to interferon-gamma" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038116" secondary="chemokine (C-C motif) ligand 21 signaling pathway" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000669" secondary="negative regulation of dendritic cell apoptotic process" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039809" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048245" secondary="eosinophil chemotaxis" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051897" secondary="positive regulation of protein kinase B signaling" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010560" secondary="positive regulation of glycoprotein biosynthetic process" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000406" secondary="positive regulation of T cell migration" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010820" secondary="positive regulation of T cell chemotaxis" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048260" secondary="positive regulation of receptor-mediated endocytosis" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EKI" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000259607" version="SP_185" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001811" version="SP_185"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSKGCKRTERSQTPKGP</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-15304-1" id="1012029">
                <names>
                    <shortLabel>ccl21-ccr7-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-3401601" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15304-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1012026</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1012030">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-3401604" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1012027</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1012031">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-3401605" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1012028</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>proximity</shortLabel>
                        <fullName>proximity</fullName>
                        <alias typeAc="MI:1041" type="synonym">close-contact colocalization</alias>
                        <alias typeAc="MI:1041" type="synonym">neighbourhood interaction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">fig. 6c</attribute>
                    <attribute name="agonist" nameAc="MI:0625">heparan sulfate</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
