UniProt UniProt http://www.uniprot.org kops-2005-4 ZW10 links mitotic checkpoint signaling to the structural kinetochore. xenla Xenopus laevis (African clawed frog) African clawed frog fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Kops GJ., Kim Y., Weaver BA., Mao Y., McLeod I., Yates JR., Tagaya M., Cleveland DW. Apoptosis - Interactions involving proteins with a function related to apoptosis dcleveland@ucsd.edu J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation kops-2005-3 ZW10 links mitotic checkpoint signaling to the structural kinetochore. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Kops GJ., Kim Y., Weaver BA., Mao Y., McLeod I., Yates JR., Tagaya M., Cleveland DW. Apoptosis - Interactions involving proteins with a function related to apoptosis dcleveland@ucsd.edu J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation kops-2005-1 ZW10 links mitotic checkpoint signaling to the structural kinetochore. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 tap tandem affinity purification TAP TAP tap mudpit multidimensional protein identification technology mudpit Kops GJ., Kim Y., Weaver BA., Mao Y., McLeod I., Yates JR., Tagaya M., Cleveland DW. Apoptosis - Interactions involving proteins with a function related to apoptosis dcleveland@ucsd.edu J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation kops-2005-5 ZW10 links mitotic checkpoint signaling to the structural kinetochore. xenla-oocyte Xenopus laevis oocyte Oocyte anti bait coip anti bait coimmunoprecipitation anti bait coip polyclonal western polyclonal antibody western blot polyclonal western Kops GJ., Kim Y., Weaver BA., Mao Y., McLeod I., Yates JR., Tagaya M., Cleveland DW. Apoptosis - Interactions involving proteins with a function related to apoptosis dcleveland@ucsd.edu J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation kops-2005-2 ZW10 links mitotic checkpoint signaling to the structural kinetochore. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti tag coip anti tag coimmunoprecipitation anti tag coip polyclonal western polyclonal antibody western blot polyclonal western Kops GJ., Kim Y., Weaver BA., Mao Y., McLeod I., Yates JR., Tagaya M., Cleveland DW. Apoptosis - Interactions involving proteins with a function related to apoptosis dcleveland@ucsd.edu J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation q8jgt8_xenla bub1b.L BUBR1 bub1b protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MAQAGDEWELSKENVQPLRQGRVMSTLQEVLSQQESASHTAVQQQKQAFELELRFYAGDDPLDVWDRYIKWAEQAFPQGGKESNLCPLLERGVKIFHEEQRYYDDLRYLNICLKFANFCSEPLDLYSYLHSQGIGVSHSLLYITWAEQFEARGNFKKADSMFQQGMQCKAEPLEKLEIHHRQFQARVSRQVLQGISEGPDVEEPELSEPQRSSLADLKSRGKTKAKVPVNRVGDSIKSRPQGLGLQAAPPQQIPNRSRFSVFDENAAMSAAQELPSLTPQQWTAPPPARSKENEQRARPWNSGRPSRNGHQAPVSELPQSLPSFTPYVDEGAQHQTVTPCKINPAVTSVLSSRKPGKDEDPLQRVQNNSQGKEETVMYCKDKVYAGVEEFSLEEIRAEIYMAKVRRKREDDLQASALRRQDMERQIEEMERQLKGSCIGSKETVIEQPAHNVEPIITPCNSKTSESICAPQQEPGMEFPLCFEMADAAPTLPRMGILPVSDVLGNNHNSSGLSPALSCDMPFTIFDESSEALPSMSVPKTIAAPVRRPLAVVSKTKSESQLTDTLDGIEHLNEEAIVCGSGKNKSLFPDPEDTCDFVRAAHLASTPFHRARDESEESLQRNSAERLPLQEKTPVCEESYRQELCIKKLSPILEASQEDTRTSVSSVSSISSTTSMFTSKTLPLSEKLELATQITGVYESEPTTEELPQAEEIAELHRQLLELLPELLVSPEIQHEVGTMPDLKEQEELVLGCETYSLKNEVILHPNSKLFMGAPVDWDMEEMKAFALKVDYQPVPWDLYVTLQLKERLGDLFETFFMEQTNCFLYQNGCISLYKDINRFSIQEILLDSEELIKEVIVLVTYNLLSLVEKLHSVEIVHGDLRPETLLLDDKIFDLSSSLELEGLFKMVDFSHSMDLKLCPTMSSLRGFPIAQSESGQQFLNPQSSPYQVDILGIADLVHLMIFRKPLQLNQENSVWTICKEVPRLRGGNLWNQFFTKILNAEGPSTCVLRELKGEMMELFDSGFQDKLCNYFIQLEMRLNPL q498i0_xenla zw10.L LOC445850 zw10 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MASFVTEVLANSGRLEKEDLGTKIRRLSRRVDELKGEVCDTINKKYDEFLPSMQSAEDLVTQVHGLVSDVDVLKSRIETEVKSDLKVAVNEFTELKQQLEKNTVILGVLKQLQEFDSAIEKYNCALTGKNYISAARHLEKAHSCLKVLKSRKGCELKLLKSFGIELTVQKQNLLYHLGEEWQQLAVWKLPPSKENSSMEMIMKTELHLCTLPSNDESTTVPLLGSVLQAFAILGELNTKLKFFSQLLLNYILKPLVSYPSLHAQMETQQQGVILRFERIETQLEHPPPAEVFIKLRLVFELLHKHLLDVPVEDSPQTGETGKVVLADVLGEMIWEEISEAIIKDCLVYSIPNNSSKLVQYEEVINATEEFENALKGMNYLKGDATELLKYARNVNAHFASKKCQDVIVVARNLMTSEIHNTVKITPDSKITLPVLPKCEDSEKVIKKEKKLSQEAPGLENDVKLNQHTFALPTCRISESVQKLMELAYQTLSEATASSKPCSIQLFYTVRNIFHLFYDVVPTYHKENLQKLPQLSAIHHNNCMYIAHHLLTLGHQFRYHLPSPLSDGAATFVDMVPGFRRLGTESFLAQMRSQKGDLLERLSNARNLSNMEDEDNYTAAHKAIRQVVHQLSRLGKVWQDVLPVAIYCKAMGTLLNTTIVEMIGKITALEDISTEDGERLYTLCRTMIEEGPLLFTPMAEEIKNKKFQEEVPLYVQKWMKFKEQLIILQASLQEIVDRWADGKGPLAVEFSTSEVKNLIRALFQNTERRAAALAKIK kntc1_xenla protein protein xenla Xenopus laevis (African clawed frog) African clawed frog GTRASKHVFEKNLRPKALKLKNAEHCSIITKETARTVLTIQSYLQSISNPEWAAAIAHKIAQELPTGPDKIHALKFCLHLAEKWKKNVSSENDAHEKADVFIKKLSVQYQRSATENVLITHKLNTPELLKQIGKPANLIVSLYEHSSVEQRIRHPTGRDYPDIHTAAKQISEVNNLNMSKICTLLLEKWICPPAVPQADKNKDVFGDIHGDEDLRRVIYLLQPYPVDYSSRMLYAIATSATS An amino acid sequence which is not represented in UniProt q6gpd1_xenla mad1l1.L Xmad1 mad1-A mad1l1 XELAEV_18045235mg protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MDDSEDNTTVISTLRSFNKFLSQPLEGTAPSLGTSTSTGASLQMQFQQRFLLEDQAAQIRSKSNLIQVEREKMQMELSHKRARIELEKAASTNAKNYEREADRNQGLHTRIKALEEKENEFQNKLQEQNEMIKSYKKTIEAQSKKLLEKEDKLSESNENISVLKGKASELQWKIMNQEMQIKTQETEKQELTEQLEIHRKKLQESNEKMQALHELQAQNADNEQKIKSLEQKLSAQEQDAAIVKSMKSDLTKLPKLERELQQLRDENAYHREMKENNALLKEEVEGLRRAAERFNKMKEDLVGSEIEKEQLVKKLKLWENLEHTTGLNIRTPDDFSRQIMAVQQRELKLKEENMTIHNSARMLETSRQQLQEELLKVQSGFLEEKKRREHQEALVRRLQKRVLLLTKERDGMRAILDSYDSELTPTEHSPQLSRRLKEAEDILQKVQDHNAEMETQLSEALEDAGIQKQKSELLTAELKVLKSQMGSSDQTMSFTNEAMSALRLKIEELEAERGRLEEENKILEMRLESLNLQGCYDPSRTKVIHLSLNPASKAKQQRTDTVRHLQEECDKLREIVRILEGGAQIPDKLEATGSPQSSQELAELKKQVESAELKNQRLREVFQTKIHEFRTACYMLTGYRIDITTENQYRLTSMYGEHKEDNLLFKASGSSGGKMQLLETDFSLTLRDFIDLHLHHQNSIPAFLSAVTLDLFSRQTFA p79935_xenla mad2l1.S mad2l1 XELAEV_18009381mg protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MAGQLTREGITLKGSAEIVSEFFFCGINSILYQRGIYPSETFTRIQKYGLTLLVSTDPALKEYLNKVTDQLKDWLYKCQVQKLVVVITSIDSNEILERWQFDIECDKTVKDGIVREKSQKVIQEEIRSVIRQITATVTFLPLLETACAFDLLIYTDKDLEVPEKWEESGPQFVSNSEEVRLRSFTTTIHKVNSMVAYKKIDTF kif2c_xenla Kinesin-like protein KIF2C Kinesin central motor 1 kif2c kcm1 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MERLVATRLVTGLAVKIMRSNGVIHNANITSVNMDRSSVNVEWKEGEANKGKEISFADVISVNPELLDAVLAPTNVKENMPPQRNVSSQNHKRKTISKIPAPKEVAAKNSLLSESGAQSVLRERSTRMTAIHETLPYENEMEAESTPLPIQQNSVQARSRSTKVSIAEEPRLQTRISEIVEESLPSGRNNQGRRKSNIVKEMEKMKNKREEQRAQNYERRMKRAQDYDTSVPNWEFGKMIKEFRATMDCHRISMADPAEEHRICVCVRKRPLNKQELSKKEIDIISVPSKNIVLVHEPKLKVDLTKYLENQAFRFDFSFDETATNEVVYRFTARPLVQSIFEGGKATCFAYGQTGSGKTHTMGGDFSGKSQNVSKGVYAFASRDVFLLLDQPRYKHLDLDVFVTFFEIYNGKVFDLLNKKTKLRVLEDAKQEVQVVGLLEKQVISADDVFKMIEIGSACRTSGQTFANTSSSRSHACLQIILRRGSKLHGKFSLVDLAGNERGVDTASADRITRMEGAEINRSLLALKECIRALGQNKSHTPFRESKLTQILRDSFIGENSRTCMIAMLSPGFNSCEYTLNTLRYADRVKELSPQNAETNDDNLQMEDSGGSHASIEGLQLQDDFLLKDEELSTHNSFQDALNRVGELEDKAVDELRELVQKEPEWTNLLQMTEQPDYDLENFVMQAEYLIQERSKVLIALGDSINSLRLALQVEEQASKQISKKKRSNK cenpa_xenla Histone H3-like centromeric protein A cenpa Centromere protein A protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MRPGSTPPSRRKSRPPRRVSPPLPTTSRTSPRRPHAQQQRRASRASPKKRFRPGTRALMEIRKYQKSTELLIRKAPFSRLVREVCMTYACGMNYNWQSMALMALQEASEAFLVRLFEDSYLCSLHAKRVTLYVQDIQLARRIRGVNEGLG zwint_human ZW10 interactor ZW10-interacting protein 1 ZWINT protein protein human Homo sapiens Human MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDRVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP zw10_human Centromere/kinetochore protein zw10 homolog ZW10 protein protein human Homo sapiens Human MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK md1l1_human Mitotic spindle assembly checkpoint protein MAD1 Mitotic arrest deficient 1-like protein 1 Mitotic checkpoint MAD1 protein homolog Tax-binding protein 181 MAD1L1 MAD1 TXBP181 protein protein human Homo sapiens Human MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA bub1_human Mitotic checkpoint serine/threonine-protein kinase BUB1 BUB1A BUB1 BUB1L protein protein human Homo sapiens Human MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGNNMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPPVVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSGAEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTLPDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGLPQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLECKRSRK bub1b_human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta MAD3/BUB1-related protein kinase Mitotic checkpoint kinase MAD3L SSK1 BUB1B BUBR1 MAD3L Protein SSK1 protein protein human Homo sapiens Human MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETARQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVTICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIYSQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQSPWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKLFWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSHLNKALWKVGKLTSPGALLFQ dc1i1_human Cytoplasmic dynein 1 intermediate chain 1 DYNC1I1 DNCIC1 Cytoplasmic dynein intermediate chain 1 Dynein intermediate chain 1, cytosolic DNCI1 protein protein human Homo sapiens Human MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA mis12_human Protein MIS12 homolog MIS12 protein protein human Homo sapiens Human MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQIRKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKEIEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVSLVQNSRKLQNIRDNVEKESKRLKIS spc24_human Kinetochore protein Spc24 SPBC24 SPC24 protein protein human Homo sapiens Human MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLYLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQLSRKFISDYLWSLVDTEW knl1_human Kinetochore scaffold 1 KNL1 ALL1-fused gene from chromosome 15q14 protein Bub-linking kinetochore protein CASC5 Cancer susceptibility candidate gene 5 protein Cancer/testis antigen 29 KIAA1570 Kinetochore-null protein 1 Protein CASC5 Protein D40/AF15q14 protein protein human Homo sapiens Human MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVSFADTIKVFQTESHMKIVRKSEMEGCSAMVPSQLQLLPPGFKRFSCLSLPETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCRQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH dsn1_human Kinetochore-associated protein DSN1 homolog DSN1 C20orf172 MIS13 protein protein human Homo sapiens Human MTSVTRSEIIDEKGPVMSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ ndc80_human Kinetochore protein NDC80 homolog Kinetochore protein Hec1 Kinetochore-associated protein 2 Highly expressed in cancer protein Retinoblastoma-associated protein HEC NDC80 HEC KNTC2 HEC1 protein protein human Homo sapiens Human MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLSINKPTSERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQEREKEPNRLESLRKLKASLQGDVQKYQAYMSNLESHSAILDQKLNGLNEEIARVELECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELKYARGKEAIETQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRAQVYVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITESKRSVRTLKEEVQKLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSENIKEIRDKYEKKATLIKSSEE cetn3_human Centrin-3 CETN3 CEN3 protein protein human Homo sapiens Human MSLALRSELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI pmf1_human Polyamine-modulated factor 1 PMF1 protein protein human Homo sapiens Human MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTDCYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKEPAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQVQAQQQAWQALHREQRELVAVLREPE kntc1_human Kinetochore-associated protein 1 Rough deal homolog KNTC1 KIAA0166 protein protein human Homo sapiens Human MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISSEKASLNPKIQACSLSDGFIIVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLLTNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVDFSTAKKLQGQIKSSFISTENYHTLGCLSLVAGDLASEVPVIIGGTGNCAFSKWEPDSSKKGMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLTTEADSPSSVTWQGITNLKLIALTASANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGISTDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQWITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKLCPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTDELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIVFRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHIKAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNIKTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAATICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSEDGIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQNLQESSQWELALRFVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAVIFIRENATTLLHKVFNCRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISLVGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENIDMDTSLILEYCSTFQLDCDAVLQLFIETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALEMVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSILKHLKSYRRISPPVDLEYQYMLEHVITLPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTLLLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLSIVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLHIQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAAAKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPSELFELQEDEALRRVQYLLLSRPIDYSSRMLFVFATSTTTTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDCSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMNTNNITELVNYLANDLSLDEASVLITEYSKHCGKPVPPDTAPCEILKMFLSGLS zwilc_human Protein zwilch homolog ZWILCH protein protein human Homo sapiens Human MWERLNCAAEDFYSRLLQKFNEEKKGIRKDPFLYEADVQVQLISKGQPNPLKNILNENDIVFIVEKVPLEKEETSHIEELQSEETAISDFSTGENVGPLALPVGKARQLIGLYTMAHNPNMTHLKINLPVTALPPLWVRCDSSDPEGTCWLGAELITTNNSITGIVLYVVSCKADKNYSVNLENLKNLHKKRHHLSTVTSKGFAQYELFKSSALDDTITASQTAIALDISWSPVDEILQIPPLSSTATLNIKVESGEPRGPLNHLYRELKFLLVLADGLRTGVTEWLEPLEAKSAVELVQEFLNDLNKLDGFGDSTKKDTEVETLKHDTAAVDRSVKRLFKVRSDLDFAEQLWCKMSSSVISYQDLVKCFTLIIQSLQRGDIQPWLHSGSNSLLSKLIHQSYHGTMDTVSLSGTIPVQMLLEIGLDKLKKDYISFFIGQELASLNHLEYFIAPSVDIQEQVYRVQKLHHILEILVSCMPFIKSQHELLFSLTQICIKYYKQNPLDEQHIFQLPVRPTAVKNLYQSEKPQKWRVEIYSGQKKIKTVWQLSDSSPIDHLNFHKPDFSELTLNGSLEERIFFTNMVTCSQVHFK cs025_human UPF0449 protein C19orf25 C19orf25 protein protein human Homo sapiens Human MGSKAKKRVLLPTRPAPPTVEQILEDVRGAPAEDPVFTILAPEDPPVPFRMMEDAEAPGEQLYQQSRAYVAANQRLQQAGNVLRQRCELLQRAGEDLEREVAQMKQAALPAAEAASSG rint1_human RAD50-interacting protein 1 RAD50 interactor 1 RINT1 protein protein human Homo sapiens Human MLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLMTNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKDKLTSDFEEILAQLHWPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASPSVILPIQVMLTPLQKRFRYHFRGNRQTNVLSKPEWYLAQVLMWIGNHTEFLDEKIQPILDKVGSLVNARLEFSRGLMMLVLEKLATDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPGTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDITDVDEMKVPDCAETFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRASLGFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLERLKHDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLLQLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLPATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK zw10_bub1b_1 colocalization of zw10 and bubr1 by immunofluorescence microscopy 507787 N/A 507792 unspecified role unspecified role neutral component neutral component N/A 507793 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 3E, 5A, 5E kntc1_bub1b_1 colocalization of kntc1 and bubr1 by immunofluorescence microscopy 507787 N/A 507794 unspecified role unspecified role neutral component neutral component N/A 507792 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 3E, 5A, 5E mad1_bub1b_1 colocalization of mad1and bubr1 by immunofluorescence microscopy 507787 N/A 507792 unspecified role unspecified role neutral component neutral component N/A 507795 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 5 mad2_bub1b_1 colocalization of mad2 and bubr1 by immunofluorescence microscopy 507787 N/A 507792 unspecified role unspecified role neutral component neutral component N/A 507796 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 5A kcm1_bub1b_1 colocalization of kcm1 and bubr1 by immunofluorescence microscopy 507787 N/A 507792 unspecified role unspecified role neutral component neutral component N/A 507797 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 5A cenpa_bub1b_1 colocalization of cenpa and bubr1 by immunofluorescence microscopy 507787 N/A 507792 unspecified role unspecified role neutral component neutral component N/A 507798 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 5A zwint_zw10_2 colocalization of zwint and zw10 by immunofluorescence microscopy 507788 N/A 507799 unspecified role unspecified role neutral component neutral component N/A 507800 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 2C mad1l1_zw10_1 colocalization of mad1 and zw10 by immunofluorescence microscopy 507788 N/A 507800 unspecified role unspecified role neutral component neutral component N/A 507801 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 7B zw10_bub1_1 colocalization of zw10 and bub1 by immunofluorescence microscopy 507788 N/A 507800 unspecified role unspecified role neutral component neutral component N/A 507802 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 7D zw10_bub1b_2 colocalization of zw10 and bubr1 by immunofluorescence microscopy 507788 N/A 507803 unspecified role unspecified role neutral component neutral component N/A 507800 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 7F zw10_dync1l1_1 colocalization of zw10 and dync1l1 by immunofluorescence microscopy 507788 N/A 507800 unspecified role unspecified role neutral component neutral component N/A 507804 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Fig. 7A zwint_kntc2_1 coIP; bait=zwint, preys=c20orf172, casc5, cetn3, kntc2, mis12, pmf1 and spbc24 507789 N/A 507805 unspecified role unspecified role prey prey N/A 507806 unspecified role unspecified role prey prey N/A 507807 unspecified role unspecified role prey prey N/A 507808 unspecified role unspecified role prey prey N/A 507799 unspecified role unspecified role bait bait n-terminal tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false N/A 507809 unspecified role unspecified role prey prey N/A 507810 unspecified role unspecified role prey prey N/A 507811 unspecified role unspecified role prey prey association association false false false Fig. 1D zw10_zwilch_1 coIP; bait=zw10, preys=c19orf25, kntc1, rint1 and zwilch 507789 N/A 507812 unspecified role unspecified role prey prey N/A 507813 unspecified role unspecified role prey prey N/A 507800 unspecified role unspecified role bait bait n-terminal tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false N/A 507814 unspecified role unspecified role prey prey N/A 507815 unspecified role unspecified role prey prey association association false false false Fig. 1E kntc1_zw10_1 coIP: bait=kntc1, prey=zw10 507790 N/A 507793 unspecified role unspecified role prey prey N/A 507794 unspecified role unspecified role bait bait physical association physical association false false false 4A zw10_kntc1_1 coIP: bait=zw10, prey=kntc1 507790 N/A 507793 unspecified role unspecified role bait bait N/A 507794 unspecified role unspecified role prey prey physical association physical association false false false 4A zwint_zw10_1 coIP; bait=zwint, prey=zw10 507791 N/A 507800 unspecified role unspecified role prey prey N/A 507799 unspecified role unspecified role bait bait n-terminal tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false physical association physical association false false false 2A