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    <entry>
        <source releaseDate="2006-09-22+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
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                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
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                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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        </source>
        <experimentList>
            <experimentDescription id="514097">
                <names>
                    <shortLabel>liu-2003a-1</shortLabel>
                    <fullName>The structure of a Bcl-xL/Bim fragment complex: implications for Bim function.</fullName>
                </names>
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                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Liu X., Dai S., Zhu Y., Marrack P., Kappler JW.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
                    <attribute name="journal" nameAc="MI:0885">Immunity (1074-7613)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2003</attribute>
                    <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
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            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="514098">
                <names>
                    <shortLabel>b2cl1_mouse</shortLabel>
                    <fullName>Bcl-2-like protein 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Apoptosis regulator Bcl-X</alias>
                    <alias typeAc="MI:0301" type="gene name">Bcl2l1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Bcl2l</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Bclx</alias>
                </names>
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                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEAERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK</sequence>
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                <names>
                    <shortLabel>b2l11_mouse</shortLabel>
                    <fullName>Bcl-2-like protein 11</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Bcl2-interacting mediator of cell death</alias>
                    <alias typeAc="MI:0301" type="gene name">Bcl2l11</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Bim</alias>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042475" secondary="odontogenesis of dentin-containing tooth" version="SP_190"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-111446" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010942" secondary="positive regulation of cell death" version="SP_190"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-193648" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007283" secondary="spermatogenesis" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035148" secondary="tube formation" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043583" secondary="ear development" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048070" secondary="regulation of developmental pigmentation" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048536" secondary="spleen development" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060139" secondary="positive regulation of apoptotic process by virus" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902110" secondary="positive regulation of mitochondrial membrane permeability involved in apoptotic process" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008017" secondary="microtubule binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" secondary="positive regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008584" secondary="male gonad development" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_997564.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" secondary="in utero embryonic development" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019898" secondary="extrinsic component of membrane" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030879" secondary="mammary gland development" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048563" secondary="post-embryonic animal organ morphogenesis" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008630" secondary="intrinsic apoptotic signaling pathway in response to DNA damage" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043029" secondary="T cell homeostasis" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A2ALQ6" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014771" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090200" secondary="positive regulation of release of cytochrome c from mitochondria" version="SP_190"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000110341" version="SP_190" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1PQ1" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043525" secondary="positive regulation of neuron apoptotic process" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O54920" version="SP_72" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045787" secondary="positive regulation of cell cycle" version="SP_190"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29214N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000027381" version="SP_190" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_033884.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001822" secondary="kidney development" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007127" secondary="meiosis I" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015040" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002260" secondary="lymphocyte homeostasis" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002262" secondary="myeloid cell homeostasis" version="SP_190"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000105970" version="SP_190" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007160" secondary="cell-matrix adhesion" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034263" secondary="positive regulation of autophagy in response to ER overload" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001776" secondary="leukocyte homeostasis" version="SP_190"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAKQPSDVSSECDREGGQLQPAERPPQLRPGAPTSLQTEPQGNPDGEGDRCPHGSPQGPLAPPASPGPFATRSPLFIFVRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASIRQSQEEPEDLRPEIRIAQELRRIGDEFNETYTRRVFANDYREAEDHPQMVILQLLRFIFRLVWRRH</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="514100">
                <names>
                    <shortLabel>bcl2l1-bcl2l11-1</shortLabel>
                    <fullName>Crystal structure of bcl-xl-bim</fullName>
                </names>
                <xref>
                    <primaryRef db="rcsb pdb" dbAc="MI:0460" id="1PQ1" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1037127" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>514097</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="514101">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1037131" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>514098</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="514102">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1037132" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="196"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="7111">
                                <names>
                                    <shortLabel>trini</shortLabel>
                                    <fullName>Trichoplusia ni (Cabbage looper)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Cabbage looper</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="514103">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1037128" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>514099</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="514104">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1037129" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="139"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="171"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="7111">
                                <names>
                                    <shortLabel>trini</shortLabel>
                                    <fullName>Trichoplusia ni (Cabbage looper)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Cabbage looper</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="assembly">dimeric, multimeric</attribute>
                    <attribute name="3d-r-factors" nameAc="MI:0631">working 78.100%, free 76.300%</attribute>
                    <attribute name="3d-resolution" nameAc="MI:0632">1.65A</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
