IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ carroll-2003-1 Analysis of the subunit composition of complex I from bovine heart mitochondria. bovin-heart Bos taurus heast heart Heart [Cardiac; Cardiac tissue] chromatography chromatography technology column chromatography chromatography fingerprinting peptide massfingerprinting fingerprinting Carroll J., Fearnley IM., Shannon RJ., Hirst J., Walker JE. Apoptosis - Interactions involving proteins with a function related to apoptosis Complexes isolated from bovine heart and purified by ammonium sulphate precipitation followed by gel filtration. Sub-complexes were further separated on a salt gradient over an ion exchange column. Proteins were separated by 2D gel electrophoresis and identified following MALD-TOF and Q-TOF mass spectometry. jh@mrc-dunn.cam.ac.uk Mol. Cell Proteomics (1535-9476) 2003 Only protein-protein interactions imex curation nduaa_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 NADH-ubiquinone oxidoreductase 42 kDa subunit Complex I-42kD protein protein bovin Bos taurus (Bovine) Bovine MALRLLRLVPPRVGGIHTSVQFKLQYGPLAYILGEKATKKMTEKSKLITVDGNICSGKSKLAKEIAEKLGLKHFPEAGIHYVDSTTGDGKPLPVQFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTICEYLPPHVVVYVDVPVPEVQSRIQKKGNPHEMKITSAYLQDIENAYKGTFLPEMSEKCEVLQYSAWEAQDAEKVVEDIEYLKYDKGPWLDQNDRNLHKLRMLVQDKLEVLNYTSIPVFLPEVTVGAHQSDQVFQEFTELPGRKYRAGYNEDVGDKWIWLK nduac_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 NADH-ubiquinone oxidoreductase subunit B17.2 Complex I-B17.2 protein protein bovin Bos taurus (Bovine) Bovine MELLQVLKRGLQQVSGHGGLRGYLRVLFRANDVRVGTLVGEDKYGNKYYEDNKQFFGRHRWVIYTTEMNGKNTFWDVDGSMVPPEWHRWLHCMTDDPPTVKPPTARKFIWTNHKFNLSGTPQQYVPYSTTRKKIQEWVPPSTPYK ndua3_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 NADH-ubiquinone oxidoreductase B9 subunit Complex I-B9 protein protein bovin Bos taurus (Bovine) Bovine MAERVAAFLKNVWAKEPVLVASFAIAGLAVILPTLSPYTKYSLMINRATPYNYPVPLRDDGNMPDVPSHPQDPQGPSLEWLKRL ndub3_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 NADH-ubiquinone oxidoreductase B12 subunit Complex I-B12 protein protein bovin Bos taurus (Bovine) Bovine MAHGHGHEHGPSKMELPDYKQWKIEGTPLETVQEKLAARGLRDPWGRNEAWRYMGGFANNVSFVGALLKGFKWGFAAFVVAIGAEYYLESQKKDKKHH nu2m_bovin NADH-ubiquinone oxidoreductase chain 2 MT-ND2 MTND2 NADH2 ND2 NADH dehydrogenase subunit 2 protein protein bovin Bos taurus (Bovine) Bovine MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLMKKMTFLPTMVVLSTMMLPLTPMLSVLE nu4m_bovin NADH-ubiquinone oxidoreductase chain 4 MT-ND4 MTND4 NADH4 ND4 NADH dehydrogenase subunit 4 protein protein bovin Bos taurus (Bovine) Bovine MLKYIIPTIMLMPLTWLSKNNMIWVNSTAHSLLISFTSLLLMNQFGDNSLNFSLLFFSDSLSTPLLILTMWLLPLMLMASQHHLSKENLTRKKLFITMLISLQLFLIMTFTAMELILFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALIYIQNTVGSLNFLMLQYWVQPVHNSWSNVFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMLRITLILNPMTDFMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVVMSTFSWSNITIILMGVNMVITALYSLYMLIMTQRGKYTYHINNISPSFTRENALMSLHILPLLLLTLNPKIILGPLY ndub7_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 NADH-ubiquinone oxidoreductase B18 subunit Complex I-B18 protein protein bovin Bos taurus (Bovine) Bovine MGAHLARRYLGDASVEPDPLRMPTFPPDYGFPERKEREMVATQQEMNDAQLVLQQRDYCAHYLIRFLKCKRDSFPNFLACKHERHDWDYCEHLDYVKRMKEFERERRLLQRKKRREQREADMAKGLGPGEVAPEVAL nduab_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 NADH-ubiquinone oxidoreductase subunit B14.7 Complex I-B14.7 protein protein bovin Bos taurus (Bovine) Bovine MAKTVLRQYWDIPEGTECHRKTYATTSIGGAAGLVVSAYSVALKTPTSFLEGVARTGRYTFTAAAIGAIFGLTSCISAQVREKPDDPLNYLIGGCAGGLILGARTRSYGIGAAACAYMGLTAALVKMGQLEGWQVFAEPKV ndua7_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 CI-B14-5A NADH-ubiquinone oxidoreductase subunit B14.5a Complex I-B14.5a protein protein bovin Bos taurus (Bovine) Bovine MASATRFIQWLRNWASGRDLQAKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRREAMPPSIVMSSQKVLVAGKPAESSAVAASEKKAVSPAPPIKRWELSQDEPYL nduc2_bovin NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 NADH-ubiquinone oxidoreductase subunit B14.5b Complex I-B14.5b protein protein bovin Bos taurus (Bovine) Bovine MMTGRQGRATFQFLPDEARSLPPPKLTDPRLAFVGFLGYCSGLIDNAIRRRPVLLAGLHRQLLYITSFVFVGYYLLKRQDYMYAVRDHDMFSYIKSHPEDFPEKDKKTYGEVFEEFHPVR ndub4_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 NADH-ubiquinone oxidoreductase B15 subunit Complex I-B15 protein protein bovin Bos taurus (Bovine) Bovine MSFPKYEASRLSSLPTTLDPAEYDISSETRKAQAERLAIRSRLKREYQLQYYDPSRRGVIEDPALVRWTYARSANIYPNFRPNTKTSLLGALFGIGPLVFWYYVFKTDRDRKEKLIQEGKLDRTFNISY ndua2_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 NADH-ubiquinone oxidoreductase B8 subunit Complex I-B8 protein protein bovin Bos taurus (Bovine) Bovine MAAAAAIRGVRGKLGLREIRIHLCQRSPGSQGVRDFIEKRYVELKKANPDLPILIRECSDVQPKLWARYAFGQEKNVSLNNFSADQVTRALENVLSSKA ndub6_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 NADH-ubiquinone oxidoreductase B17 subunit Complex I-B17 protein protein bovin Bos taurus (Bovine) Bovine MSGYTPEEKLRLQQLRELRRRWLKDQELSPREPVLPPQRVSPVERFWNKFLQDGALWKNVIYKTYRHSIFAFTHVLIPVWIIHYYLKYHVTTKPYTIVEKKPRIFPGDTILETGEVIPPMKEFPDQHH ndua5_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 NADH-ubiquinone oxidoreductase 13 kDa-B subunit Complex I-13kD-B Complex I subunit B13 protein protein bovin Bos taurus (Bovine) Bovine MAGLLKKTTGLVGLAVCETPHERLKILYTKILDVLGHIPKNAAYRKYTEQITNEKLSMVKAEPDVKKLEERLQGGQIEEVILQAENELSLARKMIQWKPWEPLVEEPPASQWKWPI nduad_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 GRIM19 NADH-ubiquinone oxidoreductase B16.6 subunit Complex I-B16.6 Gene associated with retinoic-interferon-induced mortality 19 protein Cell death regulatory protein GRIM-19 protein protein bovin Bos taurus (Bovine) Bovine MAASKVKQDMPPVGGYGPIDYKRNLPRRGLSGYSMFAVGIGALLFGYWSMMKWNRERRRLQIEDFEARIALMPLLQAEKDRRVLQMLRENLEEEATVMKDVPGWKVGESVFHTTRWVTPMMGELYGLRASEEVLSATYGFIWYT nu1m_bovin NADH-ubiquinone oxidoreductase chain 1 MT-ND1 MTND1 NADH1 ND1 NADH dehydrogenase subunit 1 protein protein bovin Bos taurus (Bovine) Bovine MFMINILMLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEPLRPATSSASMFILAPIMALGLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLITTQEQMWLILPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYANIIMMNIFTAILFLGTSHNPHMPELYTINFTIKSLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSLPILTSGIPPQT nu3m_bovin NADH-ubiquinone oxidoreductase chain 3 MT-ND3 MTND3 NADH3 ND3 NADH dehydrogenase subunit 3 protein protein bovin Bos taurus (Bovine) Bovine MNLMLALLTNFTLATLLVIIAFWLPQLNVYSEKTSPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQTANLNTMLTMALFLIILLAVSLAYEWTQKGLEWTE ndua6_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 NADH-ubiquinone oxidoreductase B14 subunit Complex I-B14 protein protein bovin Bos taurus (Bovine) Bovine MAASGLRQAAVAASTSVKPIFSRDMNEAKRRVRELYRAWYREVPNTVHLFQLDISVKQGRDKVREMFKKNAHITDPRVVDLLVIKGKMELEETIKVWKQRTHVMRFFHETEAPRPKDFLSKFYVGHDP nu5m_bovin NADH-ubiquinone oxidoreductase chain 5 MT-ND5 MTND5 NADH5 ND5 NADH dehydrogenase subunit 5 protein protein bovin Bos taurus (Bovine) Bovine MNMFSSLSLVTLLLLTMPIMMMSFNTYKPSNYPLYVKTAISYAFITSMIPTMMFIHSGQELIISNWHWLTIQTLKLSLSFKMDYFSMMFIPVALFVTWSIMEFSMWYMYSDPNINKFFKYLLLFLITMLILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRIGDIGFILAMAWFLTNLNTWDLQQIFMLNPSDSNMPLIGLALAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLTENNKYIQSITLCLGAITTLFTAMCALTQNDIKKIIAFSTSSQLGLMMVTIGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGGLFKAMPFTTTALIVGSLALTGMPFLTGFYSKDLIIEAANTSYTNAWALLMTLIATSFTAIYSTRIIFFALLGQPRFPTLVNINENNPLLINSIKRLLIGSLFAGYIISNNIPPTTIPQMTMPYYLKTTALIVTILGFILALEISNMTKNLKYHYPSNAFKFSTLLGYFPTIMHRLAPYMNLSMSQKSASSLLDLIWLEAILPKTISLAQMKASTLVTNQKGLIKLYFLSFLITILISMILFNFHE acpm_bovin Acyl carrier protein, mitochondrial NDUFAB1 NADH-ubiquinone oxidoreductase 9.6 kDa subunit CI-SDAP protein protein bovin Bos taurus (Bovine) Bovine MAVRVLCACVRRLPTAFAPLPRLPTLAAARPLSTTLFAAETRTRPGAPLPALVLAQVPGRVTQLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE ndub5_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 NADH-ubiquinone oxidoreductase SGDH subunit Complex I-SGDH protein protein bovin Bos taurus (Bovine) Bovine MAAMSLLHRASVSAVAALSGRRLGTRLGFGGFLTRDFPKTVAPVRHSGDHGKRLFIIKPSGFYDKRFLKLLRFYILLTGIPVAIGITLINVFIGEAELAEIPEGYVPEHWEYFKHPISRWIARTFFDGPEKNYERTMAILQIEAEKAELRLKELEVRRLMRARGDGPWFHYPTIDKELIDHSPKATPDN nduv3_bovin NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 NADH-ubiquinone oxidoreductase 9 kDa subunit Complex I-9kD protein protein bovin Bos taurus (Bovine) Bovine MAASLLLRQGRAGALKTVLLEAGVFRGVAPAVSLSAESGKNEKGLPPNPKKQSPPKKPVSAAPTEPFDNTTYKNLQHHDYSTYTFLDLNLDLSKFRMPQPSSGRESPRH ndub1_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 NADH-ubiquinone oxidoreductase MNLL subunit Complex I-MNLL protein protein bovin Bos taurus (Bovine) Bovine MNLLQVVRDHWVHVLVPMGFVFGYYLDRKNDEKLTAFRNKSLLYKRELKPNEEVTWK ndua1_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 NADH-ubiquinone oxidoreductase MWFE subunit Complex I-MWFE protein protein bovin Bos taurus (Bovine) Bovine MWFEVLPGIAVMGVCLFIPGMATARIHRFSNGGKEKRVAHYPYQWYLMERDRRVSGVNRSYVSKGLENID nduv2_bovin NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 NADH-ubiquinone oxidoreductase 24 kDa subunit NADH dehydrogenase subunit II protein protein bovin Bos taurus (Bovine) Bovine MFLSAALRARAAGLAAHWGKHIRNLHKTAVQNGAGGALFVHRDTPENNPETPFDFTPENYKRIEAIVKNYPEGHKAAAVLPVLDLAQRQNGWLPISAMNKVAEILQVPPMRVYEVATFYTMYNRKPVGKYHIQVCTTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVNAPMVQINDNYYEDLTPKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLTEPPKGPGFGVQAGL ndus7_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 NADH-ubiquinone oxidoreductase 20 kDa subunit Complex I-20kD PSST subunit protein protein bovin Bos taurus (Bovine) Bovine MAALAALRLLHPILAVRSGVGAALQVRGVHSSMAADSPSSTQPAVSQARAVVPKPAALPSSRGEYVVAKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQKKIKREKRLRIWYRR ndua9_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 NADH-ubiquinone oxidoreductase 39 kDa subunit Complex I-39kD protein protein bovin Bos taurus (Bovine) Bovine MAAAVHPRVVRVLPMSRSSVPALAASVFHSPPQRQLHHAVIPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPHRCEPYDTMHLRPMGDLGQIIFMDWNGRDKDSIRRAVEHSSVVINLVGREWETQNFDFEDVFVKIPQAIAQVSKEAGVEKFIHISHLNADIKSSSKYLRSKAVGEKEVRETFPEATIIKPAEIFGREDRFLNYFANIRWFGGVPLISLGKKTVKQPVYIVDVTKGIINAIKDPDARGKTFAFVGPSRYLLFDLVQYVFAVAHRPFLPYPLPHFAYRWIGRLFEISPFEPWTTRDKVERIHTTDKILPHLPGLEDLGVEATPLELKAIEVLRRHRTYRWLSSEIEDVQPAKTIPTSGP ndub9_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 UQOR22 NADH-ubiquinone oxidoreductase B22 subunit Complex I-B22 protein protein bovin Bos taurus (Bovine) Bovine MAFLSSGAYLTHQQKVLRLYKRALRHLESWCIHRDKYRYFACLLRARFDEHKNEKDMVKATQLLREAEEEFWHGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWHPSEKAMYPDYFAKREQWKKLRRESWEREVKQLQEETPVGGPRTEALPPARKQGDLPPLWWHIVTRPRERPM nduc1_bovin NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 NADH-ubiquinone oxidoreductase KFYI subunit Complex I-KFYI protein protein bovin Bos taurus (Bovine) Bovine MAPSALLRPFWKLLAPARFPSVSSSRSKFYIQEPPHGSPNWLKVGLTLGTSVFLWIYLIKQHNEDVLEYKRRNGLE ndus2_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 NADH-ubiquinone oxidoreductase 49 kDa subunit Complex I-49kD protein protein bovin Bos taurus (Bovine) Bovine MAALRALCRLRGAAAQVLRPGAGVRLPIQPSRGARQWQPDVEWAEQYGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGLMDDIYEFSKNFSLRIDELEEMLTNNRIWRNRTVDIGIVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSIRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR ndus6_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 NADH-ubiquinone oxidoreductase 13 kDa-A subunit Complex I-13kD-A protein protein bovin Bos taurus (Bovine) Bovine MAAVLTFLRFLGRGGAVTRGLPGGARCFGVRTSPTGEKVTHTGQVYDDGDYRKVRFVGRQKEVNENFAIDLIAEQPVSQVGSRVISCDGGGGALGHPRVYINLDKETKTGTCGYCGLQFRQQHH ndub8_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 NADH-ubiquinone oxidoreductase ASHI subunit Complex I-ASHI protein protein bovin Bos taurus (Bovine) Bovine MAAARAGVLGVRWLQKAARNVVPLGARTASHITKDMLPGPYPKTPEERAAAAKKYNMRVEDYEPYPDDGTGYGDYPKLPDRSQQERDPWYDWDHPDLRLNWGEPMHWDLDMYIRNRVDTSPTPVNWNLMCKHLFGFVAFMLFMFWVGETYPAYQPVGPKQYPYNNLYLERGGDPNKEPEPVVHYEI ndubb_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NDUFB11 NADH-ubiquinone oxidoreductase ESSS subunit Complex I-ESSS protein protein bovin Bos taurus (Bovine) Bovine MAARMLGLCGRRLLAVAATRGLPAARVRWESSSSRAVIAPSTLAGKRPSEPTLRWQEDPEPEDENLYEKNPDSHGYDKDPAVDIWNMRVVFFFGFSIVLVLGSTFVAYLPDYRMQEWARREAERLVKYREAHGLPIMESNCFDPSKIQLPEDED ndub2_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 NADH-ubiquinone oxidoreductase AGGG subunit Complex I-AGGG protein protein bovin Bos taurus (Bovine) Bovine MAGMSALKRLAPFAHVGGHLFRGRCARAAGARGVRRAGGGAHIEPRYRQFPQLTRSQVIQAEFFSATMWFWILWRFWHDSDAVLGHFPYPDPSQWTDEELGIPPDDED ndua8_bovin NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 NADH-ubiquinone oxidoreductase 19 kDa subunit Complex I-19kD Complex I-PGIV protein protein bovin Bos taurus (Bovine) Bovine MPGIVELPSLEDLKVQEVKVSSSVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNQCALEFFRQIKRHCAEPFTEYWTCIDYSGLQLFRRCRKQQAQFDECVLDKLGWVRPDLGDLSKVTKVKTDRPLPENPYHSRARPEPNPEVEGDLKPARHGSRLFFWTM ndus8_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 NADH-ubiquinone oxidoreductase 23 kDa subunit Complex I-23kD TYKY subunit protein protein bovin Bos taurus (Bovine) Bovine MRCLTMPMLLRALAQAQAARAGHASVRGLHSSAVAATYKYVNLREPSMDMKSVTDRAAQTLLWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR ndus5_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 NADH-ubiquinone oxidoreductase 15 kDa subunit Complex I-15 kDa protein protein bovin Bos taurus (Bovine) Bovine MPFFDVQKRLGVDLDRWMTIQSAEQPHKIPSRCHAFEKEWIECAHGIGSIRAEKECKIEFEDFRECLLRQKTMKRLHAIRRQREKLIKEGKYTPPPHHSGQEEPRS ndus4_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 NADH-ubiquinone oxidoreductase 18 kDa subunit Complex I-18 kDa Complex I-AQDQ protein protein bovin Bos taurus (Bovine) Bovine MAAVSMSVALRQALWGRRVATVAAVSVSKVSTRSLSTSTWRLAQDQTRDTQLITVDEKLDITTITGVPEEHIKTRKARIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADPLSNLVLTFSTKEDAVAFAEKNGWSYDVEERKVPKPKSKSYGANFSWNKRTRVSTK ndus3_bovin NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 NADH-ubiquinone oxidoreductase 30 kDa subunit Complex I-30kD protein protein bovin Bos taurus (Bovine) Bovine MAAAVAAAARGCWQRLVGSAAPARVAGRPSVLLLPVRRESSAADTRPTVRPRNDVAHKQLSAFGEYVAEILPKYVQQVQVSCFNELEICIHPDGVIPVLTFLRDHSNAQFKSLADLTAVDIPTRQNRFEIVYNLLSLRFNSRIRVKTYTDELTPIESSVPVYKAANWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPAYRQPPESLKLEAGDTKPEAK nduba_bovin NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 NADH-ubiquinone oxidoreductase PDSW subunit Complex I-PDSW protein protein bovin Bos taurus (Bovine) Bovine MPDSWDKDVYPEPPRRTPAPSPQTSLPNPITYLTKAFDLLVDRPVTLVREFIERQHAKNKYYYYHREFRRVPDITECQEKDVLCMFEAEMQWRRDYKVDQEIVNIIQERLKACQQREGESHRQNCAKELEQFTQVVKAYQDRYHDLGAHYSARKCLAKQKQRMLAERKAAKEAAAA nduv1_bovin NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 UQOR1 NADH-ubiquinone oxidoreductase 51 kDa subunit Complex I-51kD NADH dehydrogenase flavoprotein 1 protein protein bovin Bos taurus (Bovine) Bovine MLAARRLLGGSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSRGDWYKTKEILLKGPDWILGEVKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIIRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVNNPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALIQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEERMQQFAQQHQARQAAF ndus1_bovin NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 Complex I-75kD protein protein bovin Bos taurus (Bovine) Bovine MLRIPVRKALVGLSKSSKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTHTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALIALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLQEAKKPMVILGSSALQRNDGAAILAAVSNIAQKIRTSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIQKNPPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVEGANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAHAVEEPSIC ndufs1-ndufv1-1 Bovine heart complex I components identified by mass spectrometry 599624 N/A 599625 unspecified role unspecified role neutral component neutral component N/A 599626 unspecified role unspecified role neutral component neutral component N/A 599627 unspecified role unspecified role neutral component neutral component N/A 599628 unspecified role unspecified role neutral component neutral component N/A 599629 unspecified role unspecified role neutral component neutral component N/A 599630 unspecified role unspecified role neutral component neutral component N/A 599631 unspecified role unspecified role neutral component neutral component N/A 599632 unspecified role unspecified role neutral component neutral component N/A 599633 unspecified role unspecified role neutral component neutral component N/A 599634 unspecified role unspecified role neutral component neutral component N/A 599635 unspecified role unspecified role neutral component neutral component N/A 599636 unspecified role unspecified role neutral component neutral component N/A 599637 unspecified role unspecified role neutral component neutral component N/A 599638 unspecified role unspecified role neutral component neutral component N/A 599639 unspecified role unspecified role neutral component neutral component N/A 599640 unspecified role unspecified role neutral component neutral component N/A 599641 unspecified role unspecified role neutral component neutral component N/A 599642 unspecified role unspecified role neutral component neutral component N/A 599643 unspecified role unspecified role neutral component neutral component N/A 599644 unspecified role unspecified role neutral component neutral component N/A 599645 unspecified role unspecified role neutral component neutral component N/A 599646 unspecified role unspecified role neutral component neutral component N/A 599647 unspecified role unspecified role neutral component neutral component N/A 599648 unspecified role unspecified role neutral component neutral component N/A 599649 unspecified role unspecified role neutral component neutral component N/A 599650 unspecified role unspecified role neutral component neutral component N/A 599651 unspecified role unspecified role neutral component neutral component N/A 599652 unspecified role unspecified role neutral component neutral component N/A 599653 unspecified role unspecified role neutral component neutral component N/A 599654 unspecified role unspecified role neutral component neutral component N/A 599655 unspecified role unspecified role neutral component neutral component N/A 599656 unspecified role unspecified role neutral component neutral component N/A 599657 unspecified role unspecified role neutral component neutral component N/A 599658 unspecified role unspecified role neutral component neutral component N/A 599659 unspecified role unspecified role neutral component neutral component N/A 599660 unspecified role unspecified role neutral component neutral component N/A 599661 unspecified role unspecified role neutral component neutral component N/A 599662 unspecified role unspecified role neutral component neutral component N/A 599663 unspecified role unspecified role neutral component neutral component N/A 599664 unspecified role unspecified role neutral component neutral component N/A 599665 unspecified role unspecified role neutral component neutral component N/A 599666 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table 1, Table 2, Sup Table S1-4 ndub5-ndub2-1 Bovine heart complex I-beta components identified by mass spectrometry 599624 N/A 599634 unspecified role unspecified role neutral component neutral component N/A 599647 unspecified role unspecified role neutral component neutral component N/A 599628 unspecified role unspecified role neutral component neutral component N/A 599657 unspecified role unspecified role neutral component neutral component N/A 599630 unspecified role unspecified role neutral component neutral component N/A 599643 unspecified role unspecified role neutral component neutral component N/A 599637 unspecified role unspecified role neutral component neutral component N/A 599652 unspecified role unspecified role neutral component neutral component N/A 599656 unspecified role unspecified role neutral component neutral component N/A 599631 unspecified role unspecified role neutral component neutral component N/A 599664 unspecified role unspecified role neutral component neutral component N/A 599635 unspecified role unspecified role neutral component neutral component N/A 599644 unspecified role unspecified role neutral component neutral component N/A 599658 unspecified role unspecified role neutral component neutral component N/A 599645 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table 2, Sup Table S1-2 ndufs1-nduad-1 Bovine heart complex I-alpha components identified by mass spectrometry 599624 N/A 599663 unspecified role unspecified role neutral component neutral component N/A 599632 unspecified role unspecified role neutral component neutral component N/A 599659 unspecified role unspecified role neutral component neutral component N/A 599636 unspecified role unspecified role neutral component neutral component N/A 599654 unspecified role unspecified role neutral component neutral component N/A 599642 unspecified role unspecified role neutral component neutral component N/A 599661 unspecified role unspecified role neutral component neutral component N/A 599626 unspecified role unspecified role neutral component neutral component N/A 599660 unspecified role unspecified role neutral component neutral component N/A 599635 unspecified role unspecified role neutral component neutral component N/A 599666 unspecified role unspecified role neutral component neutral component N/A 599638 unspecified role unspecified role neutral component neutral component N/A 599646 unspecified role unspecified role neutral component neutral component N/A 599633 unspecified role unspecified role neutral component neutral component N/A 599648 unspecified role unspecified role neutral component neutral component N/A 599625 unspecified role unspecified role neutral component neutral component N/A 599662 unspecified role unspecified role neutral component neutral component N/A 599650 unspecified role unspecified role neutral component neutral component N/A 599651 unspecified role unspecified role neutral component neutral component N/A 599649 unspecified role unspecified role neutral component neutral component N/A 599627 unspecified role unspecified role neutral component neutral component N/A 599655 unspecified role unspecified role neutral component neutral component N/A 599639 unspecified role unspecified role neutral component neutral component N/A 599644 unspecified role unspecified role neutral component neutral component N/A 599665 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table 2 ndufs1-nduad-2 Bovine heart complex I-lambda components identified by mass spectrometry 599624 N/A 599649 unspecified role unspecified role neutral component neutral component N/A 599666 unspecified role unspecified role neutral component neutral component N/A 599633 unspecified role unspecified role neutral component neutral component N/A 599646 unspecified role unspecified role neutral component neutral component N/A 599665 unspecified role unspecified role neutral component neutral component N/A 599655 unspecified role unspecified role neutral component neutral component N/A 599660 unspecified role unspecified role neutral component neutral component N/A 599663 unspecified role unspecified role neutral component neutral component N/A 599636 unspecified role unspecified role neutral component neutral component N/A 599654 unspecified role unspecified role neutral component neutral component N/A 599638 unspecified role unspecified role neutral component neutral component N/A 599650 unspecified role unspecified role neutral component neutral component N/A 599626 unspecified role unspecified role neutral component neutral component N/A 599632 unspecified role unspecified role neutral component neutral component N/A 599639 unspecified role unspecified role neutral component neutral component N/A 599662 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table 2