UniProt UniProt http://www.uniprot.org sugihara-2001-1 Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Sugihara T., Kaul SC., Kato J., Reddel RR., Nomura H., Wadhwa R. Apoptosis - Interactions involving proteins with a function related to apoptosis Origin of Cdkn2a inferred from sequence length. renu@cimmed.com human testis cDNA J. Biol. Chem. (0021-9258) 2001 Only protein-protein interactions imex curation sugihara-2001-2 Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Sugihara T., Kaul SC., Kato J., Reddel RR., Nomura H., Wadhwa R. Apoptosis - Interactions involving proteins with a function related to apoptosis Origin of Cdkn2a inferred from sequence length. renu@cimmed.com human testis cDNA J. Biol. Chem. (0021-9258) 2001 Only protein-protein interactions imex curation sugihara-2001-3 Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 gal4 vp16 complement gal4 vp16 complementation karyoplasmic interaction ion strategy KISS mammalian two hybrid gal4 vp16 complement predetermined predetermined participant predetermined Sugihara T., Kaul SC., Kato J., Reddel RR., Nomura H., Wadhwa R. Apoptosis - Interactions involving proteins with a function related to apoptosis Origin of Cdkn2a inferred from sequence length. renu@cimmed.com human testis cDNA J. Biol. Chem. (0021-9258) 2001 Only protein-protein interactions imex curation sugihara-2001-4 Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sugihara T., Kaul SC., Kato J., Reddel RR., Nomura H., Wadhwa R. Apoptosis - Interactions involving proteins with a function related to apoptosis Origin of Cdkn2a inferred from sequence length. renu@cimmed.com human testis cDNA J. Biol. Chem. (0021-9258) 2001 Only protein-protein interactions imex curation sugihara-2001-5 Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. mouse-nih_3t3 Mus musculus Swiss NIH 3t3 embryo fibroblast cells nih_3t3 Mouse Swiss NIH embryo contact inhibited fibroblast cells confocal microscopy confocal microscopy anti tag immunost anti tag immunostaining anti tag immunost Sugihara T., Kaul SC., Kato J., Reddel RR., Nomura H., Wadhwa R. Apoptosis - Interactions involving proteins with a function related to apoptosis Origin of Cdkn2a inferred from sequence length. renu@cimmed.com human testis cDNA J. Biol. Chem. (0021-9258) 2001 Only protein-protein interactions imex curation pex19_human Peroxisomal biogenesis factor 19 PEX19 HK33 PXF OK/SW-cl.22 Peroxin-19 Peroxisomal farnesylated protein 33 kDa housekeeping protein protein protein human Homo sapiens Human MAAAEEGCSVGAEADRELEELLESALDDFDKAKPSPAPPSTTTAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDMTSQQEFTSCLKETLSGLAKNATDLQNSSMSEEELTKAMEGLGMDEGDGEGNILPIMQSIMQNLLSKDVLYPSLKEITEKYPEWLQSHRESLPPEQFEKYQEQHSVMCKICEQFEAETPTDSETTQKARFEMVLDLMQQLQDLGHPPKELAGEMPPGLNFDLDALNLSGPPGASGEQCLIM q64364-1 Tumor suppressor ARF p19ARF Cdkn2a p19ARF Alternative reading frame Cyclin-dependent kinase inhibitor 2A protein protein mouse Mus musculus Mouse MGRRFLVTVRIQRAGRPLQERVFLVKFVRSRRPRTASCALAFVNMLLRLERILRRGPHRNPGPGDDDGQRSRSSSSAQLRCRFELRGPHYLLPPGARRSAGRLPGHAGGAARVRGSAGCARCLGSPAARLGPRAGTSRHRAIFAFRWVLFVFRWVVFVYRWERRPDRRA pex19_mouse Peroxisomal biogenesis factor 19 Pex19 Pxf Peroxisomal farnesylated protein Peroxin-19 protein protein mouse Mus musculus Mouse MAAAEEGCGVGVEDDRELEELLESALDDFDKAKPSPEHAPTISAPDASGPQKRAPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQQEFTSCLKETLSGLAKNATELQNSGMSEEELMKAMEGLGMDEGDGEASILPIMQSIMQNLLSKDVLYPSLKEITEKYPEWLQSHQDSTPPEQFEKYQQQHSVMVKICEQFEAETPTDSEATQRARFEAMLDLMQQLQALGHPPKELAGEMPPGLNFDLDALNLSGPPGANGEQCLIM cdkn2a-pex19 765143 N/A 765148 unspecified role unspecified role prey prey N/A 765149 unspecified role unspecified role bait bait physical association physical association false false false no figure cdkn2a-pex19-1 765144 N/A 765150 unspecified role unspecified role prey prey N/A 765149 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false 1A cdkn2a-pex19-2 765145 N/A 765150 unspecified role unspecified role prey prey chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 N/A-x-x 765149 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 physical association physical association false false false 1B cdkn2a-pex19-3 765146 n/a 765150 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 765149 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false 1C cdkn2a-pex19-4 765147 n/a-x-x 765150 unspecified role unspecified role neutral component neutral component region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a-x-x 765149 unspecified role unspecified role neutral component neutral component region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false colocalization colocalization false false false 2A