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                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
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                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
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                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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                <names>
                    <shortLabel>vernocchi-2013-1</shortLabel>
                    <fullName>Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid effects.</fullName>
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                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-u2-os</shortLabel>
                            <fullName>Human U2-OS osteosarcoma cell line</fullName>
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                        <cellType>
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                                <shortLabel>u2-os</shortLabel>
                                <fullName>U2-OS osteocaroma cell line</fullName>
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                        <shortLabel>antibody detection</shortLabel>
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                    <attribute name="author-list" nameAc="MI:0636">Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
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            <experimentDescription id="1546601">
                <names>
                    <shortLabel>vernocchi-2013-3</shortLabel>
                    <fullName>Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid effects.</fullName>
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                            <shortLabel>human-mcf7</shortLabel>
                            <fullName>Homo sapiens  mammary carcinoma cells</fullName>
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                    <shortLabel>gcr_human</shortLabel>
                    <fullName>Glucocorticoid receptor</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Nuclear receptor subfamily 3 group C member 1</alias>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3CLD" version="SP_273"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001409" version="SP_273"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000394464" version="SP_273" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_273"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8849473" version="SP_273"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006325" secondary="chromatin organization" version="SP_273"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-400253" version="SP_273"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000113580" version="SP_273" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DXK" version="SP_273"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902895" secondary="positive regulation of pri-miRNA transcription by RNA polymerase II" version="SP_273"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3H52" version="SP_273"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001191190.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_273"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001723" version="SP_273"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000977" secondary="RNA polymerase II transcription regulatory region sequence-specific DNA binding" version="SP_273"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K23" version="SP_273"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5G5W" version="SP_273"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000167.1"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P04150" version="SP_273"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YMO" version="SP_273"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4P6W" version="SP_273"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NHZ" version="SP_273"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK</sequence>
            </interactor>
            <interactor id="1546603">
                <names>
                    <shortLabel>cav1_human</shortLabel>
                    <fullName>Caveolin-1</fullName>
                    <alias typeAc="MI:0301" type="gene name">CAV1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CAV</alias>
                </names>
                <xref>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043407" secondary="negative regulation of MAP kinase activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010875" secondary="positive regulation of cholesterol efflux" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006816" secondary="calcium ion transport" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015031" secondary="protein transport" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006940" secondary="regulation of smooth muscle contraction" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031410" secondary="cytoplasmic vesicle" version="SP_233"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9035034" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070836" secondary="caveola assembly" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030193" secondary="regulation of blood coagulation" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071360" secondary="cellular response to exogenous dsRNA" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031623" secondary="receptor internalization" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005901" secondary="caveola" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070320" secondary="inward rectifier potassium channel inhibitor activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007595" secondary="lactation" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051001" secondary="negative regulation of nitric-oxide synthase activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903071" secondary="positive regulation of ER-associated ubiquitin-dependent protein catabolic process" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006641" secondary="triglyceride metabolic process" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0052547" secondary="regulation of peptidase activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032092" secondary="positive regulation of protein binding" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046426" secondary="negative regulation of receptor signaling pathway via JAK-STAT" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071455" secondary="cellular response to hyperoxia" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043085" secondary="positive regulation of catalytic activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019065" secondary="receptor-mediated endocytosis of virus by host cell" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034141" secondary="positive regulation of toll-like receptor 3 signaling pathway" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042532" secondary="negative regulation of tyrosine phosphorylation of STAT protein" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048550" secondary="negative regulation of pinocytosis" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051480" secondary="regulation of cytosolic calcium ion concentration" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015485" secondary="cholesterol binding" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050998" secondary="nitric-oxide synthase binding" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006874" secondary="cellular calcium ion homeostasis" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042310" secondary="vasoconstriction" version="SP_233"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8980692" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032507" secondary="maintenance of protein location in cell" version="SP_233"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-203615" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071375" secondary="cellular response to peptide hormone stimulus" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051899" secondary="membrane depolarization" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901380" secondary="negative regulation of potassium ion transmembrane transport" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038016" secondary="insulin receptor internalization" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903361" secondary="protein localization to basolateral plasma membrane" version="SP_233"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013148" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009617" secondary="response to bacterium" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" secondary="angiogenesis" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007519" secondary="skeletal muscle tissue development" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030301" secondary="cholesterol transport" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0086091" secondary="regulation of heart rate by cardiac conduction" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098911" secondary="regulation of ventricular cardiac muscle cell action potential" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030879" secondary="mammary gland development" version="SP_233"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-603614" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031901" secondary="early endosome membrane" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_233"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060355" secondary="positive regulation of cell adhesion molecule production" version="SP_233"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013408" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030674" secondary="protein-macromolecule adaptor activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098909" secondary="regulation of cardiac muscle cell action potential involved in regulation of contraction" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010524" secondary="positive regulation of calcium ion transport into cytosol" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051117" secondary="ATPase binding" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" secondary="apoptotic signaling pathway" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001937" secondary="negative regulation of endothelial cell proliferation" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060090" secondary="molecular adaptor activity" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019915" secondary="lipid storage" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072584" secondary="caveolin-mediated endocytosis" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019217" secondary="regulation of fatty acid metabolic process" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030857" secondary="negative regulation of epithelial cell differentiation" version="SP_233"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9696273" version="SP_233"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-22646-1" id="1546604">
                <names>
                    <shortLabel>cav1-nr3c1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550225" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-22646-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1546600</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1546605">
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                            <shortLabel>n/a</shortLabel>
                        </names>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550233" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1546602</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
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                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
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                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
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                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
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                            <feature id="1546606">
                                <names>
                                    <shortLabel>unknown_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550259" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
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                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                    <participant id="1546607">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550234" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1546603</interactorRef>
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                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>proximity</shortLabel>
                        <fullName>proximity</fullName>
                        <alias typeAc="MI:1041" type="synonym">close-contact colocalization</alias>
                        <alias typeAc="MI:1041" type="synonym">neighbourhood interaction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">4/5</attribute>
                    <attribute name="comment" nameAc="MI:0612">The authors conclude that  at least the first 400 amino acids of the membrane bound Glucocorticoid receptor are the product of the NR3C1 gene.</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-22646-3" id="1546608">
                <names>
                    <shortLabel>cav1-nr3c1-2</shortLabel>
                </names>
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                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550290" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-22646-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1546601</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1546609">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550294" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1546602</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1546610">
                                <names>
                                    <shortLabel>unknown_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550295" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                    <participant id="1546611">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9550293" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1546603</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>proximity</shortLabel>
                        <fullName>proximity</fullName>
                        <alias typeAc="MI:1041" type="synonym">close-contact colocalization</alias>
                        <alias typeAc="MI:1041" type="synonym">neighbourhood interaction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">4</attribute>
                    <attribute name="comment" nameAc="MI:0612">The authors conclude that  at least the first 400 amino acids of the membrane bound Glucocorticoid receptor are the product of the NR3C1 gene.</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
