#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14585	uniprotkb:O45346	intact:EBI-326049|ensemblmetazoa:R107.8.1	intact:EBI-6540076|ensemblmetazoa:F11C7.5.1|ensemblmetazoa:F11C7.5.2	psi-mi:lin12_caeel(display_long)|uniprotkb:lin-12(gene name)|psi-mi:lin-12(display_short)|uniprotkb:Abnormal cell lineage protein 12(gene name synonym)|uniprotkb:Notch-like protein lin-12(gene name synonym)|uniprotkb:R107.8(orf name)	psi-mi:osm11_caeel(display_long)|uniprotkb:osm-11(gene name)|psi-mi:osm-11(display_short)|uniprotkb:Osmotic avoidance abnormal protein 11(gene name synonym)|uniprotkb:F11C7.5(orf name)	psi-mi:"MI:0018"(two hybrid)	Komatsu et al. (2008)	pubmed:18700817|doi:10.1371/journal.pbio.0060196|imex:IM-9310	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15721604|imex:IM-9310-1|dip:DIP-87794E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_499007.1|wormbase:R107.8|ensemblmetazoa:R107.8.1(transcript)|ensemblmetazoa:WBGene00003001(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042661"(regulation of mesodermal cell fate specification)|go:"GO:0043054"(dauer exit)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|dip:DIP-25208N|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR035993|interpro:IPR036770|rcsb pdb:2FO1|rcsb pdb:3BRD|rcsb pdb:3BRF	ensemblmetazoa:F11C7.5.1(transcript)|ensemblmetazoa:F11C7.5.2(transcript)|ensemblmetazoa:WBGene00003891(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0005112"(Notch binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0040025"(vulval development)|go:"GO:0045177"(apical part of cell)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|refseq:NP_510823.1|wormbase:F11C7.5|dip:DIP-46050N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:s+lJ4eptcr8dmCYg+ZxLxPCPX1c6239	rogid:Jjcad53yq8TvgQrst0Gl4VJaLRM6239	rigid:JtiNjcMksK445nian2m4pgiPDdY	false	binding-associated region:20-323	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O45201	uniprotkb:P14585	intact:EBI-15721623|ensemblmetazoa:W09G12.4.1	intact:EBI-326049|ensemblmetazoa:R107.8.1	psi-mi:dsl1_caeel(display_long)|uniprotkb:DSL-domain containing protein dsl-1(gene name synonym)|uniprotkb:W09G12.4(orf name)|uniprotkb:dsl-1(gene name)|psi-mi:dsl-1(display_short)	psi-mi:lin12_caeel(display_long)|uniprotkb:lin-12(gene name)|psi-mi:lin-12(display_short)|uniprotkb:Abnormal cell lineage protein 12(gene name synonym)|uniprotkb:Notch-like protein lin-12(gene name synonym)|uniprotkb:R107.8(orf name)	psi-mi:"MI:0018"(two hybrid)	Komatsu et al. (2008)	pubmed:18700817|doi:10.1371/journal.pbio.0060196|imex:IM-9310	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15721641|imex:IM-9310-2|dip:DIP-87795E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:W09G12.4.1(transcript)|ensemblmetazoa:WBGene00001103(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0005112"(Notch binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007154"(cell communication)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR039178|refseq:NP_500054.1|wormbase:W09G12.4|dip:DIP-46052N	refseq:NP_499007.1|wormbase:R107.8|ensemblmetazoa:R107.8.1(transcript)|ensemblmetazoa:WBGene00003001(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042661"(regulation of mesodermal cell fate specification)|go:"GO:0043054"(dauer exit)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|dip:DIP-25208N|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR035993|interpro:IPR036770|rcsb pdb:2FO1|rcsb pdb:3BRD|rcsb pdb:3BRF	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:qONuNZdyOYH6S1pFrsRXn+qJTkg6239	rogid:s+lJ4eptcr8dmCYg+ZxLxPCPX1c6239	rigid://Mv79iKDV8ZeXE7+2RZxyPr5fc	false	-	binding-associated region:20-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45442	uniprotkb:P14585	intact:EBI-15721660|ensemblmetazoa:Y73C8B.4.1	intact:EBI-326049|ensemblmetazoa:R107.8.1	psi-mi:lag2_caeel(display_long)|uniprotkb:lag-2(gene name)|psi-mi:lag-2(display_short)|uniprotkb:let-461(gene name synonym)|uniprotkb:Y73C8B.4(orf name)|uniprotkb:Lethal protein 461(gene name synonym)	psi-mi:lin12_caeel(display_long)|uniprotkb:lin-12(gene name)|psi-mi:lin-12(display_short)|uniprotkb:Abnormal cell lineage protein 12(gene name synonym)|uniprotkb:Notch-like protein lin-12(gene name synonym)|uniprotkb:R107.8(orf name)	psi-mi:"MI:0018"(two hybrid)	Komatsu et al. (2008)	pubmed:18700817|doi:10.1371/journal.pbio.0060196|imex:IM-9310	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15721685|imex:IM-9310-3|dip:DIP-87796E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007154"(cell communication)|go:"GO:0008406"(gonad development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0043055"(maintenance of dauer)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR039178|ensemblmetazoa:WBGene00002246(gene)|ensemblmetazoa:Y73C8B.4.1(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005112"(Notch binding)|go:"GO:0005887"(integral component of plasma membrane)|refseq:NP_503877.1|wormbase:Y73C8B.4|dip:DIP-46051N	refseq:NP_499007.1|wormbase:R107.8|ensemblmetazoa:R107.8.1(transcript)|ensemblmetazoa:WBGene00003001(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042661"(regulation of mesodermal cell fate specification)|go:"GO:0043054"(dauer exit)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|dip:DIP-25208N|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR035993|interpro:IPR036770|rcsb pdb:2FO1|rcsb pdb:3BRD|rcsb pdb:3BRF	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:PCbTuy7cFbl5F1f6HWBW50GxAvI6239	rogid:s+lJ4eptcr8dmCYg+ZxLxPCPX1c6239	rigid:X1VmyUTMYDLzSmsxbpSCnESfk5o	false	binding-associated region:16-279	binding-associated region:20-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)