#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412873|imex:IM-16609-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:64E0E71AC10323CB|rigid:280SIoSiZayxk9iqTHTf+V4a5uE false his tag:?-? his tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412871|imex:IM-16609-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:2477B219B0E7118D|rigid:280SIoSiZayxk9iqTHTf+V4a5uE false maltose binding protein tag:n-n|his tag:?-? his tag:?-?|maltose binding protein tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412920|imex:IM-16609-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 1C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:EBA85D2C1D7B705D|rigid:280SIoSiZayxk9iqTHTf+V4a5uE false mutation:644-646|his tag:?-?|maltose binding protein tag:n-n mutation:644-646|his tag:?-?|maltose binding protein tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412908|imex:IM-16609-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:B7E64ECFF9623FD5|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false his tag:?-?|maltose binding protein tag:n-n his tag:?-?|maltose binding protein tag:n-n 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412976|imex:IM-16609-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:7FF32B6ADBFCCD0A|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-5 uniprotkb:O88898-5 intact:EBI-2338240|ensembl:ENSMUSP00000110963 intact:EBI-2338240|ensembl:ENSMUSP00000110963 psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412936|imex:IM-16609-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative splicing of isoform 1. isoform-comment:Produced by alternative splicing of isoform 1. figure legend:Supp. Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 intact-crc:BFC9313302ED440F|rigid:ImsvWv6BN+DxMynsYt8xRSnC8qM false his tag:c-c|maltose binding protein tag:n-n maltose binding protein tag:n-n|his tag:c-c - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-5 uniprotkb:O88898-5 intact:EBI-2338240|ensembl:ENSMUSP00000110963 intact:EBI-2338240|ensembl:ENSMUSP00000110963 psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:"MI:0030"(cross-linking study) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412869|imex:IM-16609-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative splicing of isoform 1. isoform-comment:Produced by alternative splicing of isoform 1. figure legend:Supp. Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 intact-crc:5752DA25F00BFB15|rigid:srbBxn3q8ZYuAawhbYFK/7ixQbk false his tag:c-c|maltose binding protein tag:n-n his tag:c-c|maltose binding protein tag:n-n 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412969|imex:IM-16609-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 1E|comment:A small peak indicating tetrameric protein was also observed.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:2CD25A8E45AD9C1B|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false maltose binding protein tag:n-n|his tag:?-? maltose binding protein tag:n-n|his tag:?-? 2 0 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412991|imex:IM-16609-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Figs. 1F, 1G, Table 1|comment:A small peak indicating tetrameric protein was also observed.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:1A324C674B24D732|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false his tag:?-?|maltose binding protein tag:n-n his tag:?-?|maltose binding protein tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413007|imex:IM-16609-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Figs. 1F, 1G, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:741ECAD272BE8075|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false his tag:?-?|maltose binding protein tag:n-n|mutation:644-646 his tag:?-?|maltose binding protein tag:n-n|mutation:644-646 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-5 uniprotkb:O88898-5 intact:EBI-2338240|ensembl:ENSMUSP00000110963 intact:EBI-2338240|ensembl:ENSMUSP00000110963 psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:"MI:0028"(cosedimentation in solution) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412999|imex:IM-16609-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative splicing of isoform 1. isoform-comment:Produced by alternative splicing of isoform 1. figure legend:Supp. Figs. 1F, 1H, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 intact-crc:53E42D7985CECEFF|rigid:srbBxn3q8ZYuAawhbYFK/7ixQbk false maltose binding protein tag:n-n|his tag:c-c maltose binding protein tag:n-n|his tag:c-c 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898 uniprotkb:O88898 intact:EBI-2338025|uniprotkb:O88897|uniprotkb:O88899|uniprotkb:O89097|uniprotkb:Q8C826|uniprotkb:Q9QWY9|uniprotkb:Q9QWZ0|ensembl:ENSMUSP00000110965 intact:EBI-2338025|uniprotkb:O88897|uniprotkb:O88899|uniprotkb:O89097|uniprotkb:Q8C826|uniprotkb:Q9QWY9|uniprotkb:Q9QWZ0|ensembl:ENSMUSP00000110965 psi-mi:p63_mouse(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:p63_mouse(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413041|imex:IM-16609-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120731.1|refseq:NP_001120732.1|refseq:NP_001120733.1|refseq:NP_001120734.1|refseq:NP_001120736.1|refseq:NP_001120737.1|refseq:NP_035771.1|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0010481"(epidermal cell division)|go:"GO:0001501"(skeletal system development)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001942"(hair follicle development)|go:"GO:0002039"(p53 binding)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007389"(pattern specification process)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0098773"(skin epidermis development)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:O88898|rcsb pdb:5N2O|reactome:R-MMU-6804759 refseq:NP_001120731.1|refseq:NP_001120732.1|refseq:NP_001120733.1|refseq:NP_001120734.1|refseq:NP_001120736.1|refseq:NP_001120737.1|refseq:NP_035771.1|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0010481"(epidermal cell division)|go:"GO:0001501"(skeletal system development)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001942"(hair follicle development)|go:"GO:0002039"(p53 binding)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007389"(pattern specification process)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0098773"(skin epidermis development)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:O88898|rcsb pdb:5N2O|reactome:R-MMU-6804759 psi-mi:"MI:0469"(intact) - - figure legend:Figs 2A, 2D, 2E, 3d|variable_condition:0.52|comment:lambda-phosphatase-treated TAp63alpha obtained from irradiated oocytes showed a high percentage of tetramers and only a relatively small increase in the dimer concentration compared with phosphorylated TAp63alpha|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-oocyte)|taxid:10090(Mus musculus) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:20DAD0903CBACFB8|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false - - 4 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88898 uniprotkb:O88898 intact:EBI-2338025|uniprotkb:O88897|uniprotkb:O88899|uniprotkb:O89097|uniprotkb:Q8C826|uniprotkb:Q9QWY9|uniprotkb:Q9QWZ0|ensembl:ENSMUSP00000110965 intact:EBI-2338025|uniprotkb:O88897|uniprotkb:O88899|uniprotkb:O89097|uniprotkb:Q8C826|uniprotkb:Q9QWY9|uniprotkb:Q9QWZ0|ensembl:ENSMUSP00000110965 psi-mi:p63_mouse(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:p63_mouse(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413036|imex:IM-16609-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120731.1|refseq:NP_001120732.1|refseq:NP_001120733.1|refseq:NP_001120734.1|refseq:NP_001120736.1|refseq:NP_001120737.1|refseq:NP_035771.1|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0010481"(epidermal cell division)|go:"GO:0001501"(skeletal system development)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001942"(hair follicle development)|go:"GO:0002039"(p53 binding)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007389"(pattern specification process)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0098773"(skin epidermis development)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:O88898|rcsb pdb:5N2O|reactome:R-MMU-6804759 refseq:NP_001120731.1|refseq:NP_001120732.1|refseq:NP_001120733.1|refseq:NP_001120734.1|refseq:NP_001120736.1|refseq:NP_001120737.1|refseq:NP_035771.1|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0010481"(epidermal cell division)|go:"GO:0001501"(skeletal system development)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001942"(hair follicle development)|go:"GO:0002039"(p53 binding)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007389"(pattern specification process)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0098773"(skin epidermis development)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:O88898|rcsb pdb:5N2O|reactome:R-MMU-6804759 psi-mi:"MI:0469"(intact) - - figure legend:Figs 2A|variable_condition:0|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-oocyte)|taxid:10090(Mus musculus) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:14220F244B89D5E2|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false - - 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420335|imex:IM-16609-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 4A, 4E, 6G, 6H Supp. Fig. 5A|comment:"Mutants met413gln/ile417arg cause the protein to become a dimer. The phe55ala/trp23ala/leu62ala (FWL) mutation results in the formation of tetramers. TAp63aFWL behaves similar to DeltaNp63α, which lacks the N-terminal part of the TA domain."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:70B192D0EB06CBBF|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false myc tag:n-n myc tag:n-n 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420341|imex:IM-16609-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 4C, 4G|comment:Deletion of a helical domain within the oligermerisation domain prevents tetramer formation but not dimerization.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:A139121CEED6BE68|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false myc tag:n-n|mutation:644-646 myc tag:n-n|mutation:644-646 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4413045 uniprotkb:O88898-1 - intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:p21_promoter_human_dna(display_short)|psi-mi:EBI-4413045(display_long) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413800|imex:IM-16609-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) - - isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.8x10^-7(molar) 2011/03/23 2014/10/16 - rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:689B9C92EF4FAB64 false - mutation:644-646|maltose binding protein tag:n-n|his tag:?-? - 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4413858 uniprotkb:O88898-1 - intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:cctattctagacatgtgaggacatgtcgatacttattcc(display_short)|psi-mi:EBI-4413858(display_long) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413971|imex:IM-16609-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) - - isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.8x10^-7(molar) 2011/03/23 2014/10/16 - rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:BDE83A247D546387 false - his tag:?-?|maltose binding protein tag:n-n|mutation:644-646 - 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4413045 uniprotkb:O88898-1 - intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:p21_promoter_human_dna(display_short)|psi-mi:EBI-4413045(display_long) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413786|imex:IM-16609-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) - - isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 3a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:7.5x10^-6(molar) 2011/03/23 2014/10/16 - rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:585022429179C26B false - maltose binding protein tag:n-n|his tag:?-? - 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4413858 uniprotkb:O88898-1 - intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:cctattctagacatgtgaggacatgtcgatacttattcc(display_short)|psi-mi:EBI-4413858(display_long) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413933|imex:IM-16609-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) - - isoform-comment:Produced by alternative promoter usage. figure legend:Supp. Fig. 3a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.5x10^-6(molar) 2011/03/23 2014/10/16 - rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:64A9AF92B8D1F41F false - maltose binding protein tag:n-n|his tag:?-?|mutation decreasing interaction:318-318 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4413045 uniprotkb:O88898-5 - intact:EBI-2338240|ensembl:ENSMUSP00000110963 psi-mi:p21_promoter_human_dna(display_short)|psi-mi:EBI-4413045(display_long) psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413820|imex:IM-16609-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) - - isoform-comment:Produced by alternative splicing of isoform 1. figure legend:Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.4x10^-7(molar) 2011/03/23 2014/10/16 - rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 intact-crc:2F2B6DF0A1CEB372 false - his tag:n-n|maltose binding protein tag:n-n - 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-5 intact:EBI-4413858 intact:EBI-2338240|ensembl:ENSMUSP00000110963 - psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:cctattctagacatgtgaggacatgtcgatacttattcc(display_short)|psi-mi:EBI-4413858(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4413913|imex:IM-16609-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) - - isoform-comment:Produced by alternative splicing of isoform 1. - figure legend:Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.4x10^-7(molar) 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 - intact-crc:D64CE6100CD6B2C6 false his tag:c-c|maltose binding protein tag:n-n - 4 - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0096"(pull down) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420394|imex:IM-16609-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 5H, 5I, 6I, 6J|comment:Deletion of a helical domain within the oligermerisation domain prevents tetramer formation but not dimerization.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:6D95CEDD3A23DE55|rigid:280SIoSiZayxk9iqTHTf+V4a5uE false glutathione s tranferase tag:?-?|sufficient binding region:1-136 mutation increasing interaction:55-55,59-59,62-62|mutation increasing interaction:413-413,417-417|myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0096"(pull down) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420362|imex:IM-16609-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 5F|comment:Deletion of a helical domain within the oligermerisation domain prevents tetramer formation but not dimerization.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:A08F2347D8865BBF|rigid:280SIoSiZayxk9iqTHTf+V4a5uE false myc tag:?-?|mutation increasing interaction:413-413,417-417 sufficient binding region:569-616|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88898-5 uniprotkb:O88898-1 intact:EBI-2338240|ensembl:ENSMUSP00000110963 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0096"(pull down) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420383|imex:IM-16609-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative splicing of isoform 1. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 5F|comment:Deletion of a helical domain within the oligermerisation domain prevents tetramer formation but not dimerization.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:49777113491B1E07|rigid:pwf0wOWkWiF/Vv/YittseMVIdak false myc tag:c-c sufficient binding region:608-655|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0067"(light scattering) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412867|imex:IM-16609-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:1E41D0C30E3396B2|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false mutation:644-646|maltose binding protein tag:n-n mutation:644-646|maltose binding protein tag:n-n 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0067"(light scattering) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3864015|imex:IM-16609-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:C618D58336AB2053|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false maltose binding protein tag:n-n|mutation:644-646|his tag:?-? maltose binding protein tag:n-n|mutation:644-646|his tag:?-? 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0067"(light scattering) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412841|imex:IM-16609-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:F6F462007B17F0B1|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0067"(light scattering) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412848|imex:IM-16609-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:DD7F7425C026F760|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false maltose binding protein tag:n-n|his tag:?-? maltose binding protein tag:n-n|his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-5 uniprotkb:O88898-5 intact:EBI-2338240|ensembl:ENSMUSP00000110963 intact:EBI-2338240|ensembl:ENSMUSP00000110963 psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:"MI:0067"(light scattering) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3864029|imex:IM-16609-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative splicing of isoform 1. isoform-comment:Produced by alternative splicing of isoform 1. figure legend:Fig. 1G|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 intact-crc:F53D6F1914E1059F|rigid:srbBxn3q8ZYuAawhbYFK/7ixQbk false maltose binding protein tag:n-n|his tag:c-c maltose binding protein tag:n-n|his tag:c-c 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412817|imex:IM-16609-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1B, S2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:04601D4FCFAC4956|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false maltose binding protein tag:n-n|his tag:?-? maltose binding protein tag:n-n|his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3864002|imex:IM-16609-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1B, S2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:BD118E4EE8F9204C|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-1 uniprotkb:O88898-1 intact:EBI-3863990|ensembl:ENSMUSP00000110965 intact:EBI-3863990|ensembl:ENSMUSP00000110965 psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:o88898-1(display_long)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TA*p63alpha(isoform synonym)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4412822|imex:IM-16609-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 1B, S2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 intact-crc:F561BDECBBC363C0|rigid:ogwXpfF21NUz+NSOUSPckLNidAk false maltose binding protein tag:n-n|mutation:644-646|his tag:?-? maltose binding protein tag:n-n|mutation:644-646|his tag:?-? 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-5 uniprotkb:O88898-5 intact:EBI-2338240|ensembl:ENSMUSP00000110963 intact:EBI-2338240|ensembl:ENSMUSP00000110963 psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:o88898-5(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:TA*-gamma(isoform synonym)|uniprotkb:TA*p63gamma(isoform synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4370591|imex:IM-16609-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115308(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative splicing of isoform 1. isoform-comment:Produced by alternative splicing of isoform 1. figure legend:Fig. 1B, S2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 rogid:C+x+VgJkqXLjyxngrnOzdpyqz5k10090 intact-crc:24601C98A7ED6AD8|rigid:srbBxn3q8ZYuAawhbYFK/7ixQbk false maltose binding protein tag:n-n|his tag:c-c maltose binding protein tag:n-n|his tag:c-c 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88898-2 uniprotkb:O88898-2 intact:EBI-2338228|intact:EBI-7854591|intact:MINT-4585104|intact:EBI-7854545|intact:EBI-7854480|intact:EBI-7854641|intact:EBI-7854686|ensembl:ENSMUSP00000038117 intact:EBI-2338228|intact:EBI-7854591|intact:MINT-4585104|intact:EBI-7854545|intact:EBI-7854480|intact:EBI-7854641|intact:EBI-7854686|ensembl:ENSMUSP00000038117 psi-mi:o88898-2(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:DeltaN-alpha(isoform synonym) psi-mi:o88898-2(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:DeltaN-alpha(isoform synonym) psi-mi:"MI:0071"(molecular sieving) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420477|imex:IM-16609-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000040231(transcript) intact:EBI-2338025(isoform-parent)|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000040231(transcript) psi-mi:"MI:0469"(intact) isoform-comment:Produced by alternative promoter usage. isoform-comment:Produced by alternative promoter usage. figure legend:Fig. 6A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2011/03/23 2014/10/16 rogid:eGJx8ApGG0Vk5hHN0Ye2wyFnvGM10090 rogid:eGJx8ApGG0Vk5hHN0Ye2wyFnvGM10090 intact-crc:E76157EED71C3637|rigid:BvBTE1+NtqVcpBsMtp874u3QTYo false sufficient binding region:1-561|his tag:n-n|maltose binding protein tag:n-n sufficient binding region:1-561|his tag:n-n|maltose binding protein tag:n-n 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H3D4 uniprotkb:Q9H3D4 intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731 intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731 psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym) psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Deutsch et al. (2011) pubmed:21335238|imex:IM-16609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4420514|imex:IM-16609-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway) refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6B-D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/23 2014/10/16 rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606 rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606 intact-crc:03DC0DE64517C200|rigid:QJEN0K4S99C0GvglLyZzGyusRfg false mutation decreasing interaction:59-59,55-55,62-62|sufficient binding region:48-71 15n label:?-?|sufficient binding region:397-430 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)