#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14925	uniprotkb:O88869	intact:EBI-1395008|uniprotkb:P70710|uniprotkb:Q64616|uniprotkb:Q64668|ensembl:ENSRNOP00000046774	intact:EBI-1395057	psi-mi:amd_rat(display_long)|uniprotkb:Pam(gene name)|psi-mi:Pam(display_short)	psi-mi:rasf9_rat(display_long)|uniprotkb:Rassf9(gene name)|psi-mi:Rassf9(display_short)|uniprotkb:Pcip1(gene name synonym)|uniprotkb:Pamci(gene name synonym)|uniprotkb:Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor(gene name synonym)|uniprotkb:PAM COOH-terminal interactor protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (1998)	pubmed:9837933|imex:IM-19058	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1395064|imex:IM-19058-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037132.2|rgd:3252|refseq:XP_006245660.1|refseq:XP_006245661.1|ensembl:ENSRNOG00000033280(gene)|ensembl:ENSRNOT00000043451(transcript)|go:"GO:0001519"(peptide amidation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004504"(peptidylglycine monooxygenase activity)|go:"GO:0004598"(peptidylamidoglycolate lyase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009268"(response to pH)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018032"(protein amidation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022602"(ovulation cycle process)|go:"GO:0030141"(secretory granule)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0046688"(response to copper ion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060173"(limb development)|go:"GO:0062112"(fatty acid primary amide biosynthetic process)|interpro:IPR000323(Copper type II, ascorbate-dependent monooxygenase, N-terminal)|interpro:IPR000720(Peptidyl-glycine alpha-amidating monooxygenase)|interpro:IPR001258(NHL repeat)|interpro:IPR008977(PHM/PNGase F-fold)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR014783(Copper type II, ascorbate-dependent monooxygenase, C-terminal)|interpro:IPR014784(Copper type II, ascorbate-dependent monooxygenase-like, C-terminal)|interpro:IPR020611|interpro:IPR024548|interpro:IPR036939|rcsb pdb:1OPM|rcsb pdb:1PHM|rcsb pdb:1SDW|rcsb pdb:1YI9|rcsb pdb:1YIP|rcsb pdb:1YJK|rcsb pdb:1YJL|rcsb pdb:3FVZ|rcsb pdb:3FW0|rcsb pdb:3MIB|rcsb pdb:3MIC|rcsb pdb:3MID|rcsb pdb:3MIE|rcsb pdb:3MIF|rcsb pdb:3MIG|rcsb pdb:3MIH|rcsb pdb:3MLJ|rcsb pdb:3MLK|rcsb pdb:3MLL|rcsb pdb:3PHM|rcsb pdb:4E4Z|rcsb pdb:5WJA|rcsb pdb:5WKW|rcsb pdb:5WM0|rcsb pdb:6ALA|rcsb pdb:6ALV|rcsb pdb:6AMP|rcsb pdb:6AN3|rcsb pdb:6AO6|rcsb pdb:6AY0|rcsb pdb:6NCK	interpro:IPR029071|rgd:621329|refseq:NP_075248.1|interpro:IPR000159(Ras-association)|interpro:IPR033593|interpro:IPR033633|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0012510"(trans-Golgi network transport vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0055037"(recycling endosome)	-	-	-	figure legend:1|comment:PAM-1 fragments 1-936 and DEL928-945 did not interact.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/13	2014/10/16	rogid:KC0fM5sPQvFZ41m8CKKqFyhOAFc10116	rogid:YnaekxNZKUKzvBI+qw+eINiIsbE10116	intact-crc:48F47C8686F594E6|rigid:XNSCmyavhhfnhBBJE/kJXEkAMCs	false	binding-associated region:928-976	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P14925	uniprotkb:O88869	intact:EBI-1395008|uniprotkb:P70710|uniprotkb:Q64616|uniprotkb:Q64668|ensembl:ENSRNOP00000046774	intact:EBI-1395057	psi-mi:amd_rat(display_long)|uniprotkb:Pam(gene name)|psi-mi:Pam(display_short)	psi-mi:rasf9_rat(display_long)|uniprotkb:Rassf9(gene name)|psi-mi:Rassf9(display_short)|uniprotkb:Pcip1(gene name synonym)|uniprotkb:Pamci(gene name synonym)|uniprotkb:Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor(gene name synonym)|uniprotkb:PAM COOH-terminal interactor protein 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chen et al. (1998)	pubmed:9837933|imex:IM-19058	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1395075|imex:IM-19058-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037132.2|rgd:3252|refseq:XP_006245660.1|refseq:XP_006245661.1|ensembl:ENSRNOG00000033280(gene)|ensembl:ENSRNOT00000043451(transcript)|go:"GO:0001519"(peptide amidation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004504"(peptidylglycine monooxygenase activity)|go:"GO:0004598"(peptidylamidoglycolate lyase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009268"(response to pH)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018032"(protein amidation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022602"(ovulation cycle process)|go:"GO:0030141"(secretory granule)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0046688"(response to copper ion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060173"(limb development)|go:"GO:0062112"(fatty acid primary amide biosynthetic process)|interpro:IPR000323(Copper type II, ascorbate-dependent monooxygenase, N-terminal)|interpro:IPR000720(Peptidyl-glycine alpha-amidating monooxygenase)|interpro:IPR001258(NHL repeat)|interpro:IPR008977(PHM/PNGase F-fold)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR014783(Copper type II, ascorbate-dependent monooxygenase, C-terminal)|interpro:IPR014784(Copper type II, ascorbate-dependent monooxygenase-like, C-terminal)|interpro:IPR020611|interpro:IPR024548|interpro:IPR036939|rcsb pdb:1OPM|rcsb pdb:1PHM|rcsb pdb:1SDW|rcsb pdb:1YI9|rcsb pdb:1YIP|rcsb pdb:1YJK|rcsb pdb:1YJL|rcsb pdb:3FVZ|rcsb pdb:3FW0|rcsb pdb:3MIB|rcsb pdb:3MIC|rcsb pdb:3MID|rcsb pdb:3MIE|rcsb pdb:3MIF|rcsb pdb:3MIG|rcsb pdb:3MIH|rcsb pdb:3MLJ|rcsb pdb:3MLK|rcsb pdb:3MLL|rcsb pdb:3PHM|rcsb pdb:4E4Z|rcsb pdb:5WJA|rcsb pdb:5WKW|rcsb pdb:5WM0|rcsb pdb:6ALA|rcsb pdb:6ALV|rcsb pdb:6AMP|rcsb pdb:6AN3|rcsb pdb:6AO6|rcsb pdb:6AY0|rcsb pdb:6NCK	interpro:IPR029071|rgd:621329|refseq:NP_075248.1|interpro:IPR000159(Ras-association)|interpro:IPR033593|interpro:IPR033633|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0012510"(trans-Golgi network transport vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0055037"(recycling endosome)	-	-	-	figure legend:6a|comment:Co-localization occured in perinuclear vesicles, which might be endosomes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2007/09/13	2014/10/16	rogid:KC0fM5sPQvFZ41m8CKKqFyhOAFc10116	rogid:YnaekxNZKUKzvBI+qw+eINiIsbE10116	intact-crc:E80544C5502D4334|rigid:XNSCmyavhhfnhBBJE/kJXEkAMCs	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)