#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:G5EG44	uniprotkb:G5EEH5	intact:EBI-1182971|ensemblmetazoa:R03E9.1.1	intact:EBI-1182982|ensemblmetazoa:T19B10.11.1	psi-mi:mdl1_caeel(display_long)|uniprotkb:mdl-1(gene name)|psi-mi:mdl-1(display_short)|uniprotkb:R03E9.1(orf name)	psi-mi:mxl1_caeel(display_long)|uniprotkb:mxl-1(gene name)|psi-mi:mxl-1(display_short)|uniprotkb:T19B10.11(orf name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182993	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q21663(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_509136.1|ensemblmetazoa:R03E9.1.1(transcript)|ensemblmetazoa:WBGene00003163(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|wormbase:R03E9.1	uniprotkb:P90982(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR037933|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_505856.1|ensemblmetazoa:T19B10.11.1(transcript)|ensemblmetazoa:WBGene00003509(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0071339"(MLL1 complex)|wormbase:T19B10.11	-	-	-	figure legend:2 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2014/10/16	rogid:QFcUT/YNFv92SM6ifvWU+LRUe306239	rogid:PbI7adE3kxBOJAPSolRoA5wI1yo6239	intact-crc:1864F4CDFDD8DFC3	false	sufficient binding region:89-191|his tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:G5EG44	intact:EBI-1182969	intact:EBI-1182971|ensemblmetazoa:R03E9.1.1	-	psi-mi:mdl1_caeel(display_long)|uniprotkb:mdl-1(gene name)|psi-mi:mdl-1(display_short)|uniprotkb:R03E9.1(orf name)	psi-mi:myc_max_consensus(display_short)|psi-mi:EBI-1182969(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182993	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	uniprotkb:Q21663(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_509136.1|ensemblmetazoa:R03E9.1.1(transcript)|ensemblmetazoa:WBGene00003163(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|wormbase:R03E9.1	-	-	-	-	figure legend:2 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2014/10/16	rogid:QFcUT/YNFv92SM6ifvWU+LRUe306239	crc64:8EFDDCBDE33E5DDB	intact-crc:1864F4CDFDD8DFC3	false	sufficient binding region:89-191|his tag:n-n	32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P28574	uniprotkb:G5EG44	intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903	intact:EBI-1182971|ensemblmetazoa:R03E9.1.1	psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym)	psi-mi:mdl1_caeel(display_long)|uniprotkb:mdl-1(gene name)|psi-mi:mdl-1(display_short)|uniprotkb:R03E9.1(orf name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183018	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N	uniprotkb:Q21663(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_509136.1|ensemblmetazoa:R03E9.1.1(transcript)|ensemblmetazoa:WBGene00003163(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|wormbase:R03E9.1	-	-	-	figure legend:2 B|comment:The DNA binding of the MDL-1/MAX heterodimer was weaker than that of MDL-1/MXL-1. MDL-1 did not heterodimerize with mouse c-MYC.|caution:It is not specified what cell type the mouse MAX was expressed in.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2018/06/01	rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090	rogid:QFcUT/YNFv92SM6ifvWU+LRUe306239	intact-crc:9F3ADCC36B0AA96B	false	-	sufficient binding region:89-191|his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P28574	intact:EBI-1182969	intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903	-	psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym)	psi-mi:myc_max_consensus(display_short)|psi-mi:EBI-1182969(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183018	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N	-	-	-	-	figure legend:2 B|comment:The DNA binding of the MDL-1/MAX heterodimer was weaker than that of MDL-1/MXL-1. MDL-1 did not heterodimerize with mouse c-MYC.|caution:It is not specified what cell type the mouse MAX was expressed in.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2018/06/01	rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090	crc64:8EFDDCBDE33E5DDB	intact-crc:9F3ADCC36B0AA96B	false	-	32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P28574	intact:EBI-1182969	intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903	-	psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym)	psi-mi:myc_max_consensus(display_short)|psi-mi:EBI-1182969(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183044	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N	-	-	-	-	figure legend:2 B, C|caution:It is not specified what cell type the mouse MAX and MYC were expressed in.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2018/06/01	rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090	crc64:8EFDDCBDE33E5DDB	intact-crc:D85052D1C3BD357D	false	-	32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P28574	uniprotkb:P01108	intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903	intact:EBI-1183114|uniprotkb:P70247|uniprotkb:Q3UM70|uniprotkb:Q61422|ensembl:ENSMUSP00000123821|ensembl:ENSMUSP00000123852|ensembl:ENSMUSP00000124758	psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym)	psi-mi:myc_mouse(display_long)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:Myc(gene name)|psi-mi:Myc(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183044	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N	refseq:NP_001170823.1|refseq:NP_001170824.1|refseq:NP_001170825.1|ensembl:ENSMUSG00000022346(gene)|ensembl:ENSMUST00000159327(transcript)|ensembl:ENSMUST00000160009(transcript)|ensembl:ENSMUST00000161976(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006848"(pyruvate transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009314"(response to radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016485"(protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043473"(pigmentation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044337"(canonical Wnt signaling pathway involved in positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046722"(lactic acid secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-MMU-5689880|reactome:R-MMU-8866911|reactome:R-MMU-9018519|dip:DIP-1064N	-	-	-	figure legend:2 B, C|caution:It is not specified what cell type the mouse MAX and MYC were expressed in.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2018/06/01	rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090	rogid:nmDkyD4dlB5zKDpuzjv+JEpHZS410090	intact-crc:D85052D1C3BD357D	false	-	sufficient binding region:182-439	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-1182969	uniprotkb:P28574	-	intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903	psi-mi:myc_max_consensus(display_short)|psi-mi:EBI-1182969(display_long)	psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Yuan et al. (1998)	pubmed:9764821	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N	-	-	-	figure legend:2 B, C|caution:It is not specified what cell type the mouse MAX was expressed in.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2018/06/01	crc64:8EFDDCBDE33E5DDB	rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090	intact-crc:99A4550DAB2E54EB	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:G5EEH5	uniprotkb:G5EG44	intact:EBI-1182982|ensemblmetazoa:T19B10.11.1	intact:EBI-1182971|ensemblmetazoa:R03E9.1.1	psi-mi:mxl1_caeel(display_long)|uniprotkb:mxl-1(gene name)|psi-mi:mxl-1(display_short)|uniprotkb:T19B10.11(orf name)	psi-mi:mdl1_caeel(display_long)|uniprotkb:mdl-1(gene name)|psi-mi:mdl-1(display_short)|uniprotkb:R03E9.1(orf name)	psi-mi:"MI:0047"(far western blotting)	Yuan et al. (1998)	pubmed:9764821	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P90982(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR037933|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_505856.1|ensemblmetazoa:T19B10.11.1(transcript)|ensemblmetazoa:WBGene00003509(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0071339"(MLL1 complex)|wormbase:T19B10.11	uniprotkb:Q21663(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_509136.1|ensemblmetazoa:R03E9.1.1(transcript)|ensemblmetazoa:WBGene00003163(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|wormbase:R03E9.1	-	-	-	figure legend:3 B|comment:The 32P-labeled MXL-1 does not bind the filter-bound MXL-1.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2014/10/16	rogid:PbI7adE3kxBOJAPSolRoA5wI1yo6239	rogid:QFcUT/YNFv92SM6ifvWU+LRUe306239	intact-crc:B34F6BD5D03CBE4D|rigid:yN0HdlwIypSA/2A2xlAapg16CJc	false	his tag:n-n|tag:n-n|32p radiolabel:?-?	sufficient binding region:89-191|his tag:n-n|tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:G5EG44	uniprotkb:G5EEH5	intact:EBI-1182971|ensemblmetazoa:R03E9.1.1	intact:EBI-1182982|ensemblmetazoa:T19B10.11.1	psi-mi:mdl1_caeel(display_long)|uniprotkb:mdl-1(gene name)|psi-mi:mdl-1(display_short)|uniprotkb:R03E9.1(orf name)	psi-mi:mxl1_caeel(display_long)|uniprotkb:mxl-1(gene name)|psi-mi:mxl-1(display_short)|uniprotkb:T19B10.11(orf name)	psi-mi:"MI:0047"(far western blotting)	Yuan et al. (1998)	pubmed:9764821	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1183217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q21663(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_509136.1|ensemblmetazoa:R03E9.1.1(transcript)|ensemblmetazoa:WBGene00003163(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|wormbase:R03E9.1	uniprotkb:P90982(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR037933|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_505856.1|ensemblmetazoa:T19B10.11.1(transcript)|ensemblmetazoa:WBGene00003509(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0071339"(MLL1 complex)|wormbase:T19B10.11	-	-	-	figure legend:3 C|comment:The 32P-labeled MDL-1 does not bind the filter-bound MDL-1.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/01/10	2014/10/16	rogid:QFcUT/YNFv92SM6ifvWU+LRUe306239	rogid:PbI7adE3kxBOJAPSolRoA5wI1yo6239	intact-crc:0DCE31A14FF47799|rigid:yN0HdlwIypSA/2A2xlAapg16CJc	false	his tag:n-n|tag:n-n|sufficient binding region:89-191|32p radiolabel:?-?	his tag:n-n|tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)